Cancer is a class of diseases characterized by abnormal cell growth that begins in the cells on the surface of the inner lining of the tissue of an organ caused by the alternation of cell DNA with unknown nature.
Under normal circumstances, cell growth is a natural process that happens daily to replace millions of dead cells. In some cases, acceleration of cell growth is necessary to prevent further damage to the body organ, such as cut, injure, etc., but after fulfilling their purposes, the growth of cells are back to a normal rate again regulated growth inhibitors.
In other words, healthy cell division is limited to a number of cycles. Comapred to normal cells, cells with alternation of DNA or cancer cells can grow indefinitely.
Unfortunately, skin cells sometimes overgrow while healing, leading to scar to the skin.
At the early, most people with cancer are asymptomatic, however, at the later, due to the size and the tumor, patients may experience the general cancer symptoms such as unintended weight loss, fatigue, gastrointestinal discomfort and loss of appetite and localized symptoms such as severe pain and bleeding.
Cancer can be classified by the types of cells that have become malignant.
* Carcinoma
Carcinoma is a malignant tumor found in anywhere of epithelial tissues lining the cavities, surfaces of structures and glands.
* Sarcoma
Sarcoma is a type of cancer that arises from malignantly connective tissue cells that originated from embryonic germ cells or bone, cartilage, and fat tissues and cells.
* Lymphoma and leukemia
Hematopoietic cells are multipotent stem cells that give rise to all types of blood cell, including red blood cells, white blood cells, and platelets become cancerous.
* Germ cell tumor
Cancer derived from pluripotent cells. In adults, these are most often found in the testicle and ovary but are more common in babies and young children.
* Blastoma
Blastoma is cancer derived from immature "precursor" or embryonic tissue, mostly in children.
The causes of cancer are not identified. However, most prevalent factors associated with the cancer onset include age, family history, long-term exposure to certain cancer-induced chemicals, use of tobacco and excessive alcohol drinking,..... the list goes on and on, depending on the types of cancer.
Some researchers suggested that the most common risk factor that causes cancer in the Western world may be associated with widespread obesity.
Dr. Karen Basen-Engquist, in the evaluation of obesity risk of cancer, said, "In the United States, approximately 85,000 new cancer cases per year are related to obesity. Recent research has found that as the body mass index increases by 5 kg/m2, cancer mortality increases by 10%".And, "High priorities for future research involve additional work on the underlying mechanisms, and trials to examine the effect of lifestyle behavior change and weight loss interventions on cancer and intermediate biomarkers".
The findings strong indicated the risk of cancer is increased substantially in obese.
Cranberry is an evergreen dwarf shrub, genus Vaccinium, belongings to the family Ericaceae, native to Northern America and Southern Asia. Because of its health benefits, cranberry has been cultivated in some parts of the world for commercial profit and used in traditional and herbal medicine to treat wounds, urinary disorders, diarrhea, diabetes, stomach ailments, and liver problems.
On finding a potential compound for the treatment of invasive tumors, researchers examined the potential effects of cranberry on cancer prevention and treatment.
According to the review of the medical literature by searching the database of PubMed, cranberry and/or its components may act as chemopreventive agents, that diminish the parameters associated with the onset of cancer, including the inhibition of cells oxidation and inflammatory-related processes, in vitro.
Cell proliferation and angiogenesis and metastasis involved in cancer cell invasion were also attenuated by the administration of cranberry's apoptotic activity.
Dr. Mantzorou M, the lead scientist, after taking other factors into account wrote, " Cranberry could be considered as a conglomeration of potential effective anticancer drug-like compounds".
Additionally, in chemical constituents analysis, cranberry showed inhibitory action against cancers of the esophagus, stomach, colon, bladder, prostate, glioblastoma and lymphoma.
The efficacy of anti-cancer activity was attributed to the chemical compounds that works synergistically to result in cellular death induction via apoptosis, necrosis, and autophagy, reduction of cellular proliferation, the elevation of reactive oxygen species, and modification of cytokine and signal transduction pathways, similar to those of aforementioned study.
Taken altogether, cranberry may be considered a remedy for the prevention and treatment of cancer, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Cranberries and Cancer: An Update of Preclinical Studies Evaluating the CancerInhibitory Potential of Cranberry and Cranberry Derived Constituents by Weh KM1, Clarke J2,3,4, Kresty LA. (PubMed)
(2)Cranberry as a Promising Natural Source of Potential Nutraceuticals with Anticancer Activity by Mantzorou M1, Zarros A2, Theocharis S3, Pavlidou E1, Giaginis C. (PubMed)
(3) Obesity and Cancer Risk: Recent Review and Evidence by Karen
Ovarian Cyst Miracle (tm)
Permanently and Naturally, Eliminate All Types of Ovarian Cysts Within 2 Months
Sunday, November 3, 2019
Saturday, November 2, 2019
Ashwagandha Protects the Neuron Against Brain Dysfunction
The central system is the complex of nerve tissues including the brain and spinal cord with functions to respond to the integrating sensory information.
Neuroinflammation is a process of the immune system response to harmful pathogens that induced oxidative stress to the brain.
Neuroinflammation is also the inflammation of nervous tissue associated with the immune response in the first phase of infection including infection, traumatic brain injury, toxic metabolites, or autoimmunity.
Neurological disorders are class of diseases associated with the brain, the spinal cord including the nerves that connect them.
Most common diseases of neurological disorders are dementia, including ALS. PD, Alzheimer's disease, birth defects of the brain and spinal cord, brain injury and tumor.
Back pain associated with the related nerve damage is one of the common complaints in the US that send many patients to seek help from their doctor. Believe it or not, 80% of the US population will experience back pain at some time in their lives.
There is no single cause of neuro-dysfunction. Lifestyle, infections, genetics, and nutrition-related disease, environment, and physical injuries have been found to some major prevalent factors that induce the onset of neurological abnormalities.
Furthermore, neurological disorders have been found to facilitate psychological symptoms such as anxiety and depression and physical symptoms, depending totally on the neurons affected, including partial or complete paralysis muscle weakness seen on post-stroke patients, difficulty reading and writing and poor cognitive abilities such as patients with dementia.
According to the American Addiction Center, if you experience some of the below symptoms persistently, inclduing headaches, blurry vision, persistent fatigue, changes in behavior, numbness in the legs or arms, changes in coordination or balance weakness, slurred speech and tremors, you should seek help from the professionals immediately, as these may be the first signs of neurological disorders.
Neurodegenerative diseases are the most common forms of low-grade chronic neuroinflammation, including Alzheimer's disease, vascular dementia, and dementia with Lewy bodies.
Dr. WEI-WEI CHEN, the lead scientist at the Xuzhou Central Hospital in the investigation of inflammatory cytokines and chronic neuroinflammation wrote, "Accordingly, pro-inflammatory cytokines are important in the pathophysiology of depression and dementia"
And, "These data suggest that the role of neuroinflammation in neurodegeneration must be fully elucidated, since pro-inflammatory agents, which are the causative effects of neuroinflammation, occur widely, particularly in the elderly in whom inflammatory mechanisms are linked to the pathogenesis of functional and mental impairments.".
Ashwagandha also is known as Withania somnifera is a nightshade plant in the genus of Withania, belonging to the family Solanaceae, native to the dry parts of India, North Africa, Middle East, and the Mediterranean.
The herbal medicine has been considered as Indian ginseng and used in Ayurvedic medicine over 3000 years to treat tumors and tubercular glands, carbuncles, memory loss, and ulcers and considered as anti-stress, cognition-facilitating, anti-inflammatory, and anti-aging herbal medicine.
On finding a potent compound for enhancing brain performance, researchers examined the ashwagandha effects on the neurons.
Epidemiologically, environmental stressors have been found to cause global concerns of the modern society, by rapidly increasing the incidence of a variety of pathological conditions including brain tumors, neurodegenerative & neuropsychiatric disorders.
Ashwagandha used in Indian traditional home medicine showed to process the anti-stress and remedial potential for the treatment of aging and neurodegenerative pathologies, including the environmental toxins.
Furthermore, Ashwagandha extracts and its active principles also exerted the underlying molecular mechanism(s) that inhibits the brain pathologies through the herb nootropic potency.
Moreover, in the examing the Ashwagandha leaf extracts effects, researchers found that the Ashwagandha inhibited neuroblastoma and glioma cell initiation, and reversal of Alzheimer's and Parkinson's pathologies, protection against environmental neurotoxins and enhancement of memory.
Based on the findings, researchers said, "ashwagandha supplementation is associated with significant increases in muscle mass and strength and suggests that ashwagandha supplementation may be useful in conjunction with a resistance training program".
Taken altogether, Ashwagandha may be considered a functional herb that increases body mass and strength in resistance training, pending to the result of larger sample size and multicenter study
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Nootropic potential of Ashwagandha leaves: Beyond traditional root extracts by Wadhwa R1, Konar A1, Kaul SC. (PubMed)
(2) Role of neuroinflammation in neurodegenerative diseases (Review) by Chen WW1, Zhang X1, Huang WJ. (PubMed)
Neuroinflammation is a process of the immune system response to harmful pathogens that induced oxidative stress to the brain.
Neuroinflammation is also the inflammation of nervous tissue associated with the immune response in the first phase of infection including infection, traumatic brain injury, toxic metabolites, or autoimmunity.
Neurological disorders are class of diseases associated with the brain, the spinal cord including the nerves that connect them.
Most common diseases of neurological disorders are dementia, including ALS. PD, Alzheimer's disease, birth defects of the brain and spinal cord, brain injury and tumor.
Back pain associated with the related nerve damage is one of the common complaints in the US that send many patients to seek help from their doctor. Believe it or not, 80% of the US population will experience back pain at some time in their lives.
There is no single cause of neuro-dysfunction. Lifestyle, infections, genetics, and nutrition-related disease, environment, and physical injuries have been found to some major prevalent factors that induce the onset of neurological abnormalities.
Furthermore, neurological disorders have been found to facilitate psychological symptoms such as anxiety and depression and physical symptoms, depending totally on the neurons affected, including partial or complete paralysis muscle weakness seen on post-stroke patients, difficulty reading and writing and poor cognitive abilities such as patients with dementia.
According to the American Addiction Center, if you experience some of the below symptoms persistently, inclduing headaches, blurry vision, persistent fatigue, changes in behavior, numbness in the legs or arms, changes in coordination or balance weakness, slurred speech and tremors, you should seek help from the professionals immediately, as these may be the first signs of neurological disorders.
Neurodegenerative diseases are the most common forms of low-grade chronic neuroinflammation, including Alzheimer's disease, vascular dementia, and dementia with Lewy bodies.
Dr. WEI-WEI CHEN, the lead scientist at the Xuzhou Central Hospital in the investigation of inflammatory cytokines and chronic neuroinflammation wrote, "Accordingly, pro-inflammatory cytokines are important in the pathophysiology of depression and dementia"
And, "These data suggest that the role of neuroinflammation in neurodegeneration must be fully elucidated, since pro-inflammatory agents, which are the causative effects of neuroinflammation, occur widely, particularly in the elderly in whom inflammatory mechanisms are linked to the pathogenesis of functional and mental impairments.".
Ashwagandha also is known as Withania somnifera is a nightshade plant in the genus of Withania, belonging to the family Solanaceae, native to the dry parts of India, North Africa, Middle East, and the Mediterranean.
The herbal medicine has been considered as Indian ginseng and used in Ayurvedic medicine over 3000 years to treat tumors and tubercular glands, carbuncles, memory loss, and ulcers and considered as anti-stress, cognition-facilitating, anti-inflammatory, and anti-aging herbal medicine.
On finding a potent compound for enhancing brain performance, researchers examined the ashwagandha effects on the neurons.
Epidemiologically, environmental stressors have been found to cause global concerns of the modern society, by rapidly increasing the incidence of a variety of pathological conditions including brain tumors, neurodegenerative & neuropsychiatric disorders.
Ashwagandha used in Indian traditional home medicine showed to process the anti-stress and remedial potential for the treatment of aging and neurodegenerative pathologies, including the environmental toxins.
Furthermore, Ashwagandha extracts and its active principles also exerted the underlying molecular mechanism(s) that inhibits the brain pathologies through the herb nootropic potency.
Moreover, in the examing the Ashwagandha leaf extracts effects, researchers found that the Ashwagandha inhibited neuroblastoma and glioma cell initiation, and reversal of Alzheimer's and Parkinson's pathologies, protection against environmental neurotoxins and enhancement of memory.
Based on the findings, researchers said, "ashwagandha supplementation is associated with significant increases in muscle mass and strength and suggests that ashwagandha supplementation may be useful in conjunction with a resistance training program".
Taken altogether, Ashwagandha may be considered a functional herb that increases body mass and strength in resistance training, pending to the result of larger sample size and multicenter study
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Nootropic potential of Ashwagandha leaves: Beyond traditional root extracts by Wadhwa R1, Konar A1, Kaul SC. (PubMed)
(2) Role of neuroinflammation in neurodegenerative diseases (Review) by Chen WW1, Zhang X1, Huang WJ. (PubMed)
Herbal Turmeric, a Natural and Potential Treatment of Uveitis with No Side Effects
Uveitis is a type of eye inflammation, affecting the middle layer of tissue in the eye wall (uvea).
The condition has been found to onset suddenly and get worse quickly. Most common symptoms of uveitis are eye redness, pain, and blurred vision that can affect one or both eyes.
In some cases, patients with the condition also experience symptoms of light sensitivity, floaters and decreased vision.
If you have some of the aforementioned symptoms, please check with your doctor to rule out the possibility.
The exact cause of uveitis is unknown. However, some researchers suggested that people with a compromised immune system associated with inflammatory disease and infected diseases are at an increased risk of uveitis.
Other risk factors, epidemiologically such as eye injury, diseases that affect the eye such as diabetes are also found in patients with uveitis.
Most cases of uveitis are treated by prescription eye drops in combination with anti-inflammatory medications. If all fail, surgery may be necessary.
Untreated uveitis has been found to induce complications of glaucoma, cataracts, optic nerve damage and retinal detachment.
Out of the prevalent factors of uveitis, some researchers suggested that aging associated with the weakened immune system may be the major factor that causes uveitis.
Dr, Marwan R. Abdulaal, the lead scientist said, "Uveitis is a vision-threatening inflammation of the eye that carries considerable morbidity. It is responsible for 10% of legal blindness in the United States and up to 25% in the developing world".
And. "The aging body has a changing response of the immune system, which might reflect a different pattern of uveitis in the elderly population".
Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.
The herb has been used in traditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.
On finding a natural compound for the treatment of uveitis, researchers examined the effect on turmeric administered 4 h after induction of E. coli lipopolysaccharide-induced uveitis in rats.
Compared to the control group, turmeric showed significantly suppressed inflammation with a significantly lower mean clinical grade, histopathological grade, and aqueous humor (AH) protein level, second to the conventional medicine prednisolone.
The turmeric administered 4 h did not affect proinflammatory cytokines levels of TNF-alpha levels.
However, when the aqueous extract was administered starting from 3 days before induction of uveitis, treatment group not only showed a similar effect on the mean clinical and histopathological grade, as well as AH protein but also reduced TNF-alpha levels, comparable to treatment group.
Based on the findings, researchers said, "topically applied a standardized aqueous extract of C. longa suppresses endotoxin-induced uveitis in rats by reducing TNF-alpha activity".
In order to reveal more information about turmeric anti-uveitis property, researchers examined the anterior uveitis induced in rabbits by intravitreal injection of lipopolysaccharide from Escherichia coli after pretreatment with C. longa and B. aristata aqueous extracts.
According to the clinical and histopathologic grading, anterior segment inflammation in the control group was significantly higher compared to both the extract-treated groups.
More precisely, the inflammatory cell count in the control group was 30.75 cells/mL compared to 2.39 and 11.56 cells/mL in the C. longa- and B. aristata-treated groups, respectively.
Similarly, C. longa- and B. aristata-treated groups also exerted strong effects on the protein content and TNF-alpha level as of that on the aforementioned study.
Taken altogether, turmeric may be considered supplements for the prevention and treatment of uveitis, pending to the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Topically applied standardized aqueous extract of Curcuma longa Linn. suppresses endotoxin-induced uveal inflammation in rats by Agarwal R1, Gupta SK, Agarwal P, Srivastava S. (PubMed)
(2) The anti-inflammatory effects of Curcuma longa and Berberis aristata in endotoxin-induced uveitis in rabbits by Gupta SK1, Agarwal R, Srivastava S, Agarwal P, Agrawal SS, Saxena R, Galpalli N. (PubMed)
(3) Uveitis in the Aging Eye: Incidence, Patterns, and Differential Diagnosis by Marwan R. Abdulaal, Bachir H. Abiad, and Rola N. Hamam. (PMC)
The condition has been found to onset suddenly and get worse quickly. Most common symptoms of uveitis are eye redness, pain, and blurred vision that can affect one or both eyes.
In some cases, patients with the condition also experience symptoms of light sensitivity, floaters and decreased vision.
If you have some of the aforementioned symptoms, please check with your doctor to rule out the possibility.
The exact cause of uveitis is unknown. However, some researchers suggested that people with a compromised immune system associated with inflammatory disease and infected diseases are at an increased risk of uveitis.
Other risk factors, epidemiologically such as eye injury, diseases that affect the eye such as diabetes are also found in patients with uveitis.
Most cases of uveitis are treated by prescription eye drops in combination with anti-inflammatory medications. If all fail, surgery may be necessary.
Untreated uveitis has been found to induce complications of glaucoma, cataracts, optic nerve damage and retinal detachment.
Out of the prevalent factors of uveitis, some researchers suggested that aging associated with the weakened immune system may be the major factor that causes uveitis.
Dr, Marwan R. Abdulaal, the lead scientist said, "Uveitis is a vision-threatening inflammation of the eye that carries considerable morbidity. It is responsible for 10% of legal blindness in the United States and up to 25% in the developing world".
And. "The aging body has a changing response of the immune system, which might reflect a different pattern of uveitis in the elderly population".
Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.
The herb has been used in traditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.
On finding a natural compound for the treatment of uveitis, researchers examined the effect on turmeric administered 4 h after induction of E. coli lipopolysaccharide-induced uveitis in rats.
Compared to the control group, turmeric showed significantly suppressed inflammation with a significantly lower mean clinical grade, histopathological grade, and aqueous humor (AH) protein level, second to the conventional medicine prednisolone.
The turmeric administered 4 h did not affect proinflammatory cytokines levels of TNF-alpha levels.
However, when the aqueous extract was administered starting from 3 days before induction of uveitis, treatment group not only showed a similar effect on the mean clinical and histopathological grade, as well as AH protein but also reduced TNF-alpha levels, comparable to treatment group.
Based on the findings, researchers said, "topically applied a standardized aqueous extract of C. longa suppresses endotoxin-induced uveitis in rats by reducing TNF-alpha activity".
In order to reveal more information about turmeric anti-uveitis property, researchers examined the anterior uveitis induced in rabbits by intravitreal injection of lipopolysaccharide from Escherichia coli after pretreatment with C. longa and B. aristata aqueous extracts.
According to the clinical and histopathologic grading, anterior segment inflammation in the control group was significantly higher compared to both the extract-treated groups.
More precisely, the inflammatory cell count in the control group was 30.75 cells/mL compared to 2.39 and 11.56 cells/mL in the C. longa- and B. aristata-treated groups, respectively.
Similarly, C. longa- and B. aristata-treated groups also exerted strong effects on the protein content and TNF-alpha level as of that on the aforementioned study.
Taken altogether, turmeric may be considered supplements for the prevention and treatment of uveitis, pending to the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Topically applied standardized aqueous extract of Curcuma longa Linn. suppresses endotoxin-induced uveal inflammation in rats by Agarwal R1, Gupta SK, Agarwal P, Srivastava S. (PubMed)
(2) The anti-inflammatory effects of Curcuma longa and Berberis aristata in endotoxin-induced uveitis in rabbits by Gupta SK1, Agarwal R, Srivastava S, Agarwal P, Agrawal SS, Saxena R, Galpalli N. (PubMed)
(3) Uveitis in the Aging Eye: Incidence, Patterns, and Differential Diagnosis by Marwan R. Abdulaal, Bachir H. Abiad, and Rola N. Hamam. (PMC)
Healthy Food Cucumber Reduces Pain and Symptoms of Osteoarthritis
Osteoarthritis (OA) is a chronic condition affecting the joints in the hands, knees, hips, and spine mostly occurred in older adults.
More precisely, OA is a result in which the protective cartilage on the ends of your bones wears down over time due to repetitive movement of the same joints that cause the thinning cartilage, leading to bone rubbing on bone.
According to the statistics, in the US, over 25 million people are living with OA.
The precisive characteristics of osteoarthritis are aching pain(5), stiffness(6), or difficulty of moving the joint or joints(7). The pain usually gets worse in a change of weather, at night and in the advanced diseases, the pain can occur even at rest(8).
Today management of osteoarthritis (OA) focuses on pain relief and improved physical function through pharmacological, nonpharmacological, and surgical treatments(4).
Believe it or not, other causes of OA also include
1. Process of wear and repair
Osteoarthritis (OA), widespread degenerative disease of skeletal joints(34) and is often associated with senescence invertebrates. arising from long term wear and tear, heavy long-term use or specific injuries(35).
The improper repair process of injuring of joints can also result in symptoms of Osteoarthritis (OA)(36) in old age(37), according to TCM.
2. Nutrient deficiency and overload
Poor nutritional conditions experienced early in life are linked to the greater prevalence of osteoarthritis (OA)(35)(38), such as vitamin D.
On the other hand, nutrient overload and metabolic surplus, such as obesity may contribute to the early onset of osteoarthritis (OA)(38).
3. Cartilage
Cartilage is a flexible connective tissue cushioned the ends of bones in your joints and allowed the joints to move smoothly. Rough or wears down cartilage due to aging or damage can cause pain due to the bone in the joint rubbing against another bone(39)(40).
In other words, osteoarthritis (OA) may also be the result of injuring (35), overuse(15)(16), Rheumatoid Arthritis(41), etc.
The cucumber plant is a species of Cucumis Sativus, belongs to the family Cucurbitaceae and native to Western Asia. It is a creeping vine with roots in the ground and grows up with the support of frames.
With an aim to find a potential compound for the treatment of osteoarthritis, researchers evaluated the efficacy of Q-Actin™, an aqueous extract of Cucumis sativus (cucumber; CSE) against glucosamine-chondroitin (GC) in the management of moderate knee OA.
The randomized double-blind, parallel-group clinical trial that took place in three different centers. included 122 patients (56 males and 66 females) aged between 40 and 75 years and diagnosed with moderate knee OA assigned to 2 groups (n= 61).
Among the groups, the GC group received orally the generally prescribed dose of 1,350 mg of GC twice daily and the CSE group received orally10 mg twice daily of CSE.
According to the assays, on days 30, 60, 90, 120, 150, and 180 compared to the baseline (Day 0), the WOMAC score in the CSE group was decreased by 22.44% and 70.29% on days 30 and 180, respectively, compared to a 14.80% and 32.81% respectively decrease in the GC group.
The pain scores also showed similar trends in flavor to the CSE group. There was no adverse effect on the course of the experiment.
In other words, CSE is more effective for the treatment of OA compared to that of GC.
Dr. the lead scientists wrote, "The use of 10 mg CSE, twice daily, was effective in reducing pain related to moderate knee OA and can be potentially used in the management of knee pain, stiffness, and physical functions related to OA".
Taken altogether, cucumber extract may be used for the treatment of OA, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Effectiveness of Cucumis sativus extract versus glucosamine-chondroitin in the management of moderate osteoarthritis: a randomized controlled trial by Nash RJ1, Azantsa BK2, Sharp H1, Shanmugham V. (PubMed)
(2) Most Common Disease of elder: The Clinical Trials and Studies of musculoskeletal disorders(MSDs) - Osteoarthritis: The Causes and Risk Factors by Kyle J. Norton
More precisely, OA is a result in which the protective cartilage on the ends of your bones wears down over time due to repetitive movement of the same joints that cause the thinning cartilage, leading to bone rubbing on bone.
According to the statistics, in the US, over 25 million people are living with OA.
The precisive characteristics of osteoarthritis are aching pain(5), stiffness(6), or difficulty of moving the joint or joints(7). The pain usually gets worse in a change of weather, at night and in the advanced diseases, the pain can occur even at rest(8).
Today management of osteoarthritis (OA) focuses on pain relief and improved physical function through pharmacological, nonpharmacological, and surgical treatments(4).
Believe it or not, other causes of OA also include
1. Process of wear and repair
Osteoarthritis (OA), widespread degenerative disease of skeletal joints(34) and is often associated with senescence invertebrates. arising from long term wear and tear, heavy long-term use or specific injuries(35).
The improper repair process of injuring of joints can also result in symptoms of Osteoarthritis (OA)(36) in old age(37), according to TCM.
2. Nutrient deficiency and overload
Poor nutritional conditions experienced early in life are linked to the greater prevalence of osteoarthritis (OA)(35)(38), such as vitamin D.
On the other hand, nutrient overload and metabolic surplus, such as obesity may contribute to the early onset of osteoarthritis (OA)(38).
3. Cartilage
Cartilage is a flexible connective tissue cushioned the ends of bones in your joints and allowed the joints to move smoothly. Rough or wears down cartilage due to aging or damage can cause pain due to the bone in the joint rubbing against another bone(39)(40).
In other words, osteoarthritis (OA) may also be the result of injuring (35), overuse(15)(16), Rheumatoid Arthritis(41), etc.
The cucumber plant is a species of Cucumis Sativus, belongs to the family Cucurbitaceae and native to Western Asia. It is a creeping vine with roots in the ground and grows up with the support of frames.
With an aim to find a potential compound for the treatment of osteoarthritis, researchers evaluated the efficacy of Q-Actin™, an aqueous extract of Cucumis sativus (cucumber; CSE) against glucosamine-chondroitin (GC) in the management of moderate knee OA.
The randomized double-blind, parallel-group clinical trial that took place in three different centers. included 122 patients (56 males and 66 females) aged between 40 and 75 years and diagnosed with moderate knee OA assigned to 2 groups (n= 61).
Among the groups, the GC group received orally the generally prescribed dose of 1,350 mg of GC twice daily and the CSE group received orally10 mg twice daily of CSE.
According to the assays, on days 30, 60, 90, 120, 150, and 180 compared to the baseline (Day 0), the WOMAC score in the CSE group was decreased by 22.44% and 70.29% on days 30 and 180, respectively, compared to a 14.80% and 32.81% respectively decrease in the GC group.
The pain scores also showed similar trends in flavor to the CSE group. There was no adverse effect on the course of the experiment.
In other words, CSE is more effective for the treatment of OA compared to that of GC.
Dr. the lead scientists wrote, "The use of 10 mg CSE, twice daily, was effective in reducing pain related to moderate knee OA and can be potentially used in the management of knee pain, stiffness, and physical functions related to OA".
Taken altogether, cucumber extract may be used for the treatment of OA, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Effectiveness of Cucumis sativus extract versus glucosamine-chondroitin in the management of moderate osteoarthritis: a randomized controlled trial by Nash RJ1, Azantsa BK2, Sharp H1, Shanmugham V. (PubMed)
(2) Most Common Disease of elder: The Clinical Trials and Studies of musculoskeletal disorders(MSDs) - Osteoarthritis: The Causes and Risk Factors by Kyle J. Norton
Phytochemical Allicin, the Novel Dietary Antioxidant
Phytochemicals may be the next potential sources of new medications for the treatment of diseases with little or no side effects.
Scientists may have found a dietary and bioactive ingredient for the prevention and treatment of diseases associated with oxidative stress.
Allicin is phytochemical containing sulfur in the class of organosulfur compound, found abundantly in onion and garlic.
Oxidative stress is a condition characterized by the overexpression of free radicals in the host body.
Most cases of oxidative stress are caused by the inability of the host liver in stimulating the production of antioxidant enzymes which play a critical role in inhibiting the free radical expression, causing oxidative stress.
In a healthy individual, the ratio of free radicals and antioxidant enzymes is always balanced.
However, an individual whose antioxidant enzymes were suppressed due to damage to the antioxidant enzymes' productive system or other sources may have a greater risk of the onset of oxidative stress.
Dietary antioxidant intake such as fruits and vegetable may be helpful to keep the free radical in check.
Oxidative stress has been found to cause damage to cell lipids, proteins, DNA, leading to many chronic diseases, including atherosclerosis, cancer, diabetics, rheumatoid arthritis, post-ischemic perfusion injury, myocardial infarction, cardiovascular diseases, chronic inflammation, and stroke.
The oxidative stress that causes chronic ailment is a result of a chain reaction started by free radical donate or steal an electron from another atom, leading to a domino effect which can not be stopped until all outer ring electron of free radicals is paired or inhibited by antioxidants.
A free radical is any atom or molecule that has a single unpaired electron in an outer shell and highly reactive to react with another cell.
Most free radicals and other ROS are derived internally either from normal essential metabolic processes in the human body or from external sources such as exposure to X-rays, ozone, cigarette smoking, air pollutants, and industrial chemicals.
Antioxidants are biomolecules that inhibited oxidation.
On finding a natural ingredient and whole food for the prevention and treatment of diseases associated with oxidative stress, researchers investigated the effect of allicin (the active ingredient of garlic) contained in the commercial preparation Garlicin against hydroxyl radicals (.OH) using high pressure liquid chromatographic (HPLC) method.
Allicin equivalent in Garlicin (1.8, 3.6, 7.2, 14.4, 21.6, 28.8 and 36 micrograms) produced concentration-dependent decreases in the formation of 2,3-DHBA and 2,5-DHBA, the OH adduct products.
The inhibition of formation of 2,3-DHBA and 2,5-DHBA with 1.8 micrograms/ml was 32.36% and 43.2% respectively while with 36.0 micrograms/ml the inhibition was approximately 94.0% and 90.0% respectively.
These results suggested that allicin is highly active against the OH adduct products through its free radical scavenging activity.
Furthermore, Allicin also exerted a significant antioxidant activity by preventing the lipid peroxidation of liver homogenate in a concentration-dependent manner.
Additionally, by examing the antioxidant effects of four main chemical classes, alliin, allyl cysteine, allyl disulfide, and allicin, prepared by chemical synthesis or purification, researchers discovered
* Alliin scavenged superoxide, while allyl cysteine and allyl disulfide did not react with superoxide.
* Allicin suppressed the formation of superoxide by the xanthine/xanthine oxidase system, probably via a thiol exchange mechanism.
* Allicin did not exhibit hydroxyl radical scavenging activity in this study, probably due to some unknown mechanisms.
The finding suggested that allyl disulfide, alliin, allicin, and allyl cysteine exhibit different patterns of antioxidant activities as protective compounds against free radical damage.
Taken altogether, allicin processed high levels of free radicals scavenging activity may be used for the prevention of the overexpression of ROS in the initiation of oxidative stress.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blog, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Antioxidant activity of allicin, an active principle in garlic by Prasad K, Laxdal VA, Yu M, Raney BL. (PubMed)
(2) The antioxidant properties of garlic compounds: allyl cysteine, alliin, allicin, and allyl disulfide by Chung LY. (PubMed)
Scientists may have found a dietary and bioactive ingredient for the prevention and treatment of diseases associated with oxidative stress.
Allicin is phytochemical containing sulfur in the class of organosulfur compound, found abundantly in onion and garlic.
Oxidative stress is a condition characterized by the overexpression of free radicals in the host body.
Most cases of oxidative stress are caused by the inability of the host liver in stimulating the production of antioxidant enzymes which play a critical role in inhibiting the free radical expression, causing oxidative stress.
In a healthy individual, the ratio of free radicals and antioxidant enzymes is always balanced.
However, an individual whose antioxidant enzymes were suppressed due to damage to the antioxidant enzymes' productive system or other sources may have a greater risk of the onset of oxidative stress.
Dietary antioxidant intake such as fruits and vegetable may be helpful to keep the free radical in check.
Oxidative stress has been found to cause damage to cell lipids, proteins, DNA, leading to many chronic diseases, including atherosclerosis, cancer, diabetics, rheumatoid arthritis, post-ischemic perfusion injury, myocardial infarction, cardiovascular diseases, chronic inflammation, and stroke.
The oxidative stress that causes chronic ailment is a result of a chain reaction started by free radical donate or steal an electron from another atom, leading to a domino effect which can not be stopped until all outer ring electron of free radicals is paired or inhibited by antioxidants.
A free radical is any atom or molecule that has a single unpaired electron in an outer shell and highly reactive to react with another cell.
Most free radicals and other ROS are derived internally either from normal essential metabolic processes in the human body or from external sources such as exposure to X-rays, ozone, cigarette smoking, air pollutants, and industrial chemicals.
Antioxidants are biomolecules that inhibited oxidation.
On finding a natural ingredient and whole food for the prevention and treatment of diseases associated with oxidative stress, researchers investigated the effect of allicin (the active ingredient of garlic) contained in the commercial preparation Garlicin against hydroxyl radicals (.OH) using high pressure liquid chromatographic (HPLC) method.
Allicin equivalent in Garlicin (1.8, 3.6, 7.2, 14.4, 21.6, 28.8 and 36 micrograms) produced concentration-dependent decreases in the formation of 2,3-DHBA and 2,5-DHBA, the OH adduct products.
The inhibition of formation of 2,3-DHBA and 2,5-DHBA with 1.8 micrograms/ml was 32.36% and 43.2% respectively while with 36.0 micrograms/ml the inhibition was approximately 94.0% and 90.0% respectively.
These results suggested that allicin is highly active against the OH adduct products through its free radical scavenging activity.
Furthermore, Allicin also exerted a significant antioxidant activity by preventing the lipid peroxidation of liver homogenate in a concentration-dependent manner.
Additionally, by examing the antioxidant effects of four main chemical classes, alliin, allyl cysteine, allyl disulfide, and allicin, prepared by chemical synthesis or purification, researchers discovered
* Alliin scavenged superoxide, while allyl cysteine and allyl disulfide did not react with superoxide.
* Allicin suppressed the formation of superoxide by the xanthine/xanthine oxidase system, probably via a thiol exchange mechanism.
* Allicin did not exhibit hydroxyl radical scavenging activity in this study, probably due to some unknown mechanisms.
The finding suggested that allyl disulfide, alliin, allicin, and allyl cysteine exhibit different patterns of antioxidant activities as protective compounds against free radical damage.
Taken altogether, allicin processed high levels of free radicals scavenging activity may be used for the prevention of the overexpression of ROS in the initiation of oxidative stress.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blog, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Antioxidant activity of allicin, an active principle in garlic by Prasad K, Laxdal VA, Yu M, Raney BL. (PubMed)
(2) The antioxidant properties of garlic compounds: allyl cysteine, alliin, allicin, and allyl disulfide by Chung LY. (PubMed)
Phytochemical 3,3'-Diindolylmethane, May Be A Potent Anti Malignant Mesothelioma Bioactive Compound, Scientists Show
The bioactive compound 3,3'-Diindolylmethane or DIM may process strong and positive effects against the risk and progression of mesothelioma, according to studies.
Mesothelioma is a medical condition characterized by irregular cell growth in the thin layer of tissue that covers the internal organs, due to cell DNA alternation.
However, according to the epidemiological studies, the most common area affected is the lining of the lungs and chest wall.
Most cases of mesothelioma start in the cell on the surface of the layered tissue. At the later stage, the cells of the larger size of the tumor can cause secondary tumors to develop in nearby organs and distant locations through the circulation of blood and fluids, leading secondary metastasis.
Most common symptoms of mesothelioma are persistent dry cough or wheezing, shortness of breath, pain in the chest or abdomen, fatigue and weakness.
In severe cases, patients may also experience symptoms of respiratory complications such as pleural effusion (fluid around the lungs).
If you experience some of the above symptoms, please check with your doctor to rule out the possibility.
Most common causes of mesothelioma are due to long-term exposure to asbestos as the disease is found in 80% of the patients. However, suggested that genetic preposition may also be the prevalent risk factor of the disease.
Dr. Ombretta Melaiu, the lead scientist in the investigation of the genetic susceptibility in the development of malignant pleural mesothelioma (MPM), wrote, "Among asbestos-exposed workers, several studies reported familial cases of MPM, suggesting that heredity could be important in the tumor development,.... the risk of developing MPM is increased of a limited extent among people exposed to asbestos with a positive history of familial cancers".
And, "In families and in animal models, mutations within BAP1 are strongly predisposing to develop MPM".
The results clearly suggested that if you carry the mutation gene BAP1, you are at a higher risk of MPM and other types of cancer.
3,3'-Diindolylmethane or DIM are phytochemicals derived from the digestion of indole-3-carbinol, belonging to the group of Indoles, found abundantly in broccoli, Brussels sprouts, cabbage, and kale, etc.
Scientists in the concern of malignant mesothelioma (MM), a very aggressive, lethal cancer, and its incidence is increasing worldwide examined the dietary phytochemicals which may process the potential for the treatment of MM with no side effect.
The study included several bioactive ingredients such as curcumin, epigallocatechin gallate, quercetin, genistein, pterostilbene, resveratrol, capsaicin, ellagic acid, benzyl isothiocyanate, phenethyl isothiocyanate, sulforaphane, indole-3-carbinol, 3,3'-diindolylmethane (DIM), diallyl disulfide, betulinic acid, and oleanolic acid.
DIM was found to process the anti-MM activity by boosting the function microRNA in the regulation of the activities of the genes.
Where MicroRNAs (miRNAs) are a class of small noncoding RNAs of ∼22nt in length involved in the regulation of gene expression against the incidence of cancer. Increased expression of microRNAs is associated with numerous types of cancer.
Overexpression of miR-132 in vivo was associated with the severity of cancer patients.
Injection of DIM exerted anti mesothelioma potentials, through the expression of microRNA regulatory activities.was attributed to the suppression of macrophage infiltration and pro-inflammatory cytokines.
In other words, DIM modulated the immune response against the onset and progression of mesothelioma caused by the production of oxidative stress due to the overexpression of inflammatory cytokines in the initiation of the disease.
Dr. Sayeed MA the lead scientist wrote in the final report, "In addition to microRNA regulatory activities, curcumin, epigallocatechin gallate, quercetin, genistein, resveratrol, phenethyl isothiocyanate, and sulforaphane have anti-mesothelioma potentials, and pterostilbene, capsaicin, ellagic acid, benzyl isothiocyanate, indole-3-carbinol, 3,3'-diindolylmethane, diallyl disulfide, betulinic acid, and oleanolic acid have potentials to inhibit cancer by regulating the expression of various genes which are also known to be aberrant in MM".
Taken altogether, DIM may be considered a supplement for the prevention and combined with primary therapy for the treatment of MM, pending to the confirmation of larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Regulation of microRNA using promising dietary phytochemicals: Possible preventive and treatment option of malignant mesothelioma by Sayeed MA1, Bracci M2, Lucarini G2, Lazzarini R2, Di Primio R2, Santarelli L. (PubMed)
(2) The genetic susceptibility in the development of malignant pleural mesothelioma by Ombretta Melaiu, Federica Gemignani, and Stefano Landi. (PMC)
Mesothelioma is a medical condition characterized by irregular cell growth in the thin layer of tissue that covers the internal organs, due to cell DNA alternation.
However, according to the epidemiological studies, the most common area affected is the lining of the lungs and chest wall.
Most cases of mesothelioma start in the cell on the surface of the layered tissue. At the later stage, the cells of the larger size of the tumor can cause secondary tumors to develop in nearby organs and distant locations through the circulation of blood and fluids, leading secondary metastasis.
Most common symptoms of mesothelioma are persistent dry cough or wheezing, shortness of breath, pain in the chest or abdomen, fatigue and weakness.
In severe cases, patients may also experience symptoms of respiratory complications such as pleural effusion (fluid around the lungs).
If you experience some of the above symptoms, please check with your doctor to rule out the possibility.
Most common causes of mesothelioma are due to long-term exposure to asbestos as the disease is found in 80% of the patients. However, suggested that genetic preposition may also be the prevalent risk factor of the disease.
Dr. Ombretta Melaiu, the lead scientist in the investigation of the genetic susceptibility in the development of malignant pleural mesothelioma (MPM), wrote, "Among asbestos-exposed workers, several studies reported familial cases of MPM, suggesting that heredity could be important in the tumor development,.... the risk of developing MPM is increased of a limited extent among people exposed to asbestos with a positive history of familial cancers".
And, "In families and in animal models, mutations within BAP1 are strongly predisposing to develop MPM".
The results clearly suggested that if you carry the mutation gene BAP1, you are at a higher risk of MPM and other types of cancer.
3,3'-Diindolylmethane or DIM are phytochemicals derived from the digestion of indole-3-carbinol, belonging to the group of Indoles, found abundantly in broccoli, Brussels sprouts, cabbage, and kale, etc.
Scientists in the concern of malignant mesothelioma (MM), a very aggressive, lethal cancer, and its incidence is increasing worldwide examined the dietary phytochemicals which may process the potential for the treatment of MM with no side effect.
The study included several bioactive ingredients such as curcumin, epigallocatechin gallate, quercetin, genistein, pterostilbene, resveratrol, capsaicin, ellagic acid, benzyl isothiocyanate, phenethyl isothiocyanate, sulforaphane, indole-3-carbinol, 3,3'-diindolylmethane (DIM), diallyl disulfide, betulinic acid, and oleanolic acid.
DIM was found to process the anti-MM activity by boosting the function microRNA in the regulation of the activities of the genes.
Where MicroRNAs (miRNAs) are a class of small noncoding RNAs of ∼22nt in length involved in the regulation of gene expression against the incidence of cancer. Increased expression of microRNAs is associated with numerous types of cancer.
Overexpression of miR-132 in vivo was associated with the severity of cancer patients.
Injection of DIM exerted anti mesothelioma potentials, through the expression of microRNA regulatory activities.was attributed to the suppression of macrophage infiltration and pro-inflammatory cytokines.
In other words, DIM modulated the immune response against the onset and progression of mesothelioma caused by the production of oxidative stress due to the overexpression of inflammatory cytokines in the initiation of the disease.
Dr. Sayeed MA the lead scientist wrote in the final report, "In addition to microRNA regulatory activities, curcumin, epigallocatechin gallate, quercetin, genistein, resveratrol, phenethyl isothiocyanate, and sulforaphane have anti-mesothelioma potentials, and pterostilbene, capsaicin, ellagic acid, benzyl isothiocyanate, indole-3-carbinol, 3,3'-diindolylmethane, diallyl disulfide, betulinic acid, and oleanolic acid have potentials to inhibit cancer by regulating the expression of various genes which are also known to be aberrant in MM".
Taken altogether, DIM may be considered a supplement for the prevention and combined with primary therapy for the treatment of MM, pending to the confirmation of larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Regulation of microRNA using promising dietary phytochemicals: Possible preventive and treatment option of malignant mesothelioma by Sayeed MA1, Bracci M2, Lucarini G2, Lazzarini R2, Di Primio R2, Santarelli L. (PubMed)
(2) The genetic susceptibility in the development of malignant pleural mesothelioma by Ombretta Melaiu, Federica Gemignani, and Stefano Landi. (PMC)
Friday, November 1, 2019
Phytochemical Allicin, The Natural Anti High Blood Pressure Bioactive Ingredient
Scientists may have found a bioactive ingredient that can normalize the blood pressure without inducing any side effects, according to studies.
Allicin is phytochemical containing sulfur in the class of organosulfur compound, found abundantly in onion and garlic.
Blood pressure is the force of blood pushing against the walls of the arteries as the heart pumps out blood.
High blood pressure is a condition of abnormally high blood pressure, leading to the raising pressure in your heart.
If it stays high over time it can cause hardening and stiffening arterial wall,, a major risk factor of heart diseases.
The ideal blood pressure is more than 120 over 80 and less than 140 over 90 (120/80-140/90), according to the consensus.
Abnormal high blood pressure, depending on how high of the numbers, patients may experience symptoms of a headache to a severe headache., fatigue, vision problems. However, in severe cases, high blood pressure can also induce chest pain, difficulty breathing, irregular heartbeat and confusion.
Untreated high blood pressure epidemiologically can cause complications of retinopathy, lead to damage to the retina or bleeding in the eye, blurred vision and complete loss of vision.
Blood pressure medications have undoubtedly prevented many deaths from heart disease in the past 30 years, but they have many side effects such as damaging the kidney.
If you can control your diet, such as making changes to lifestyle, maintaining ideal weight and diet with low salt, you could do just fine without the drugs.
According to the hypertension clinical guideline from the National Institute for Health and Clinical Excellence (NICE) usefully recommends regular aerobic exercise and reduction of salt, alcohol, and smoking, and advocates ‘healthy, low-calorie diets' for ‘overweight individuals with raised blood pressure'".
This suggestion once again, highlighted that high blood pressure can be prevented by a change to a healthy lifestyle.
On finding a natural ingredient for the prevention and treatment of high blood pressure with no side effects, scientists at the Clinical Research Center looked into the antihypertensive effect of a popular garlic preparation containing 1.3% allicin at a large dose (2400 mg).
Nine patients with rather severe hypertension (diastolic blood pressure > or = 115 mm Hg) were included in the study.
Application of the preparation reduced the sitting blood pressure by 7/16 (+/- 3/2 SD) mm Hg at peak effect approximately 5 hours after the dose, with a significant decrease in diastolic blood pressure (p < 0.05) from 5-14 hours after the dose.
No significant side effects were reported. The findings strongly indicate that this garlic preparation can reduce blood pressure.
Futhermore, in order to compare the antihypertensive effect of the different fractions of garlic, researchers investigated the hypotensive action of time-released garlic powder tablets (Allicor) vs regular garlic pills (Kwai).
84 men with mild or moderate arterial hypertension have participated in the study.
After an 8-week placebo treatment run-in phase, patients were randomized either to 600 mg Allicor (n=30) or to placebo (n=20) daily for 8 weeks. In addition, in the open-label branch, patients received either 2400 mg Allicor daily (n=18) or 900 mg Kwai daily (n=16).
Allicor treatment (600 mg daily) resulted in a reduction of both systolic and diastolic blood pressures by 7.0 mm Hg (95% confidence interval (95% CI): 5.3-8.7) and 3.8 mm Hg (95% CI: 2.7-4.8), respectively. Increasing the Allicor dosage to 2400 mg daily did not provide any additional benefit.
Treatment with Kwai resulted in the same decrease in systolic blood pressure (5.4 mm Hg, 95% CI: 1.9-8.8) as that seen with Allicor, but no decrease in diastolic blood pressure.
In the depth analysis, researchers found that different effects of Allicor and Kwai on diastolic blood pressure may be associated with the prolonged action of Allicor.
Dr. Sobenin IA, wrote in the final report, "The results of this study show that time-released garlic powder tablets are more effective for the treatment of mild and moderate arterial hypertension than are regular garlic supplements".
Taken altogether,. allicin, a bioactive compound of garlic may be used for the prevention and treatment of high blood pressure with no side effects
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Can garlic lower blood pressure? A pilot study by McMahon FG, Vargas R.(PubMed)
(2) Time-released garlic powder tablets lower systolic and diastolic blood pressure in men with mild and moderate arterial hypertension by Sobenin IA, Andrianova IV, Fomchenkov IV, Gorchakova TV, Orekhov AN. (PubMed)
(3) Hypertension and lifestyle modification: how useful are the guidelines? by Rachel Nicoll. (PMC)
Allicin is phytochemical containing sulfur in the class of organosulfur compound, found abundantly in onion and garlic.
Blood pressure is the force of blood pushing against the walls of the arteries as the heart pumps out blood.
High blood pressure is a condition of abnormally high blood pressure, leading to the raising pressure in your heart.
If it stays high over time it can cause hardening and stiffening arterial wall,, a major risk factor of heart diseases.
The ideal blood pressure is more than 120 over 80 and less than 140 over 90 (120/80-140/90), according to the consensus.
Abnormal high blood pressure, depending on how high of the numbers, patients may experience symptoms of a headache to a severe headache., fatigue, vision problems. However, in severe cases, high blood pressure can also induce chest pain, difficulty breathing, irregular heartbeat and confusion.
Untreated high blood pressure epidemiologically can cause complications of retinopathy, lead to damage to the retina or bleeding in the eye, blurred vision and complete loss of vision.
Blood pressure medications have undoubtedly prevented many deaths from heart disease in the past 30 years, but they have many side effects such as damaging the kidney.
If you can control your diet, such as making changes to lifestyle, maintaining ideal weight and diet with low salt, you could do just fine without the drugs.
According to the hypertension clinical guideline from the National Institute for Health and Clinical Excellence (NICE) usefully recommends regular aerobic exercise and reduction of salt, alcohol, and smoking, and advocates ‘healthy, low-calorie diets' for ‘overweight individuals with raised blood pressure'".
This suggestion once again, highlighted that high blood pressure can be prevented by a change to a healthy lifestyle.
On finding a natural ingredient for the prevention and treatment of high blood pressure with no side effects, scientists at the Clinical Research Center looked into the antihypertensive effect of a popular garlic preparation containing 1.3% allicin at a large dose (2400 mg).
Nine patients with rather severe hypertension (diastolic blood pressure > or = 115 mm Hg) were included in the study.
Application of the preparation reduced the sitting blood pressure by 7/16 (+/- 3/2 SD) mm Hg at peak effect approximately 5 hours after the dose, with a significant decrease in diastolic blood pressure (p < 0.05) from 5-14 hours after the dose.
No significant side effects were reported. The findings strongly indicate that this garlic preparation can reduce blood pressure.
Futhermore, in order to compare the antihypertensive effect of the different fractions of garlic, researchers investigated the hypotensive action of time-released garlic powder tablets (Allicor) vs regular garlic pills (Kwai).
84 men with mild or moderate arterial hypertension have participated in the study.
After an 8-week placebo treatment run-in phase, patients were randomized either to 600 mg Allicor (n=30) or to placebo (n=20) daily for 8 weeks. In addition, in the open-label branch, patients received either 2400 mg Allicor daily (n=18) or 900 mg Kwai daily (n=16).
Allicor treatment (600 mg daily) resulted in a reduction of both systolic and diastolic blood pressures by 7.0 mm Hg (95% confidence interval (95% CI): 5.3-8.7) and 3.8 mm Hg (95% CI: 2.7-4.8), respectively. Increasing the Allicor dosage to 2400 mg daily did not provide any additional benefit.
Treatment with Kwai resulted in the same decrease in systolic blood pressure (5.4 mm Hg, 95% CI: 1.9-8.8) as that seen with Allicor, but no decrease in diastolic blood pressure.
In the depth analysis, researchers found that different effects of Allicor and Kwai on diastolic blood pressure may be associated with the prolonged action of Allicor.
Dr. Sobenin IA, wrote in the final report, "The results of this study show that time-released garlic powder tablets are more effective for the treatment of mild and moderate arterial hypertension than are regular garlic supplements".
Taken altogether,. allicin, a bioactive compound of garlic may be used for the prevention and treatment of high blood pressure with no side effects
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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Can garlic lower blood pressure? A pilot study by McMahon FG, Vargas R.(PubMed)
(2) Time-released garlic powder tablets lower systolic and diastolic blood pressure in men with mild and moderate arterial hypertension by Sobenin IA, Andrianova IV, Fomchenkov IV, Gorchakova TV, Orekhov AN. (PubMed)
(3) Hypertension and lifestyle modification: how useful are the guidelines? by Rachel Nicoll. (PMC)
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