Socrates Said," Let foods be your medicine and let medicine be your foods". Let us all practice the values of the past wisdom to build a letter living and living health while we enjoy the delicious drinks

Permanent Unwanted Tattoo Removal by Tattoo Expert

Permanent Unwanted Tattoo Removal by Tattoo Expert
Safely, Painlessly, Laserlessly and Naturally in Removing any Unwanted Tattoos in 2 to 8 Weeks, Guaranteed

Monday, July 31, 2017

All About Vitamins: The Effects of Vitamin B2 In Reduced Risk of Congenital Heart Defects in Offspring

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


Vitamin B1 is one of the members of the vitamin B complex, it is also known as thiamin or thiamine. It's most common form is a colorless chemical compound with the formula C12H17N4OS. It was discovered in 1910 by Umetaro Suzuki in Japan. It is a water soluble vitamin, therefore it can be stored in the body and is required to be taken regularly.

Levels of Riboflavin may be associated to risk in developed  congenital heart defects in offspring, a recent study suggested.

In a total of 276 mothers of a child with a CHD in case-control family study, comprising of 190 outflow tract defects (OTD) and 86 non-outflow tract defects (non-OTD) and 324 control mothers of a non-malformed child, in mothers filled out general and food frequency questionnaires at 16 months after the index-pregnancy, maternal diet high in saturated fats and low in riboflavin and nicotinamide seems to contribute to CHD risk, in particular OTDs.

The study also found that mother who had a low dietary intakes of both riboflavin (<1.20 mg/d) and nicotinamide (<13.5 mg/d) expressed the increased more than two-fold the risk of a child with an OTD,

Dr. Smedts HP, the lead author said," mothers of a child with OTD, had higher dietary intakes of saturated fat, 30.9 vs. 29.8 g/d; P < 0.05. Dietary intakes of riboflavin and nicotinamide were lower in mothers of a child with an OTD than in controls (1.32 vs. 1.41 mg/d; P < 0.05 and 14.6 vs. 15.1 mg/d; P < 0.05, respectively)".

Although vitamin B2 plays an important role in reduced risk in developed congenital heart defects, other research suggested that diet low in vitamin B12 and imbalance in the maternal intake of proteins and low folate intake may also associate with an increased risk of a child with a CHD, according to the study of 192 mothers of a child with a CHD and 216 mothers of a healthy child. filling out food frequency questionnaires covering the current dietary intake.

Other study suggested that maternal diet high in saturated fats and low in riboflavin and nicotinamide seems to contribute to CHD risk, in particular OTDs.

Therefore, vitamin B2, may be associated to reduce risk of congenital heart defects, other nutrients factors should also be taken into account as well.


FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic 
Impact In Rice, Pasta, And Potatoes In Half


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic 
Impact In Rice, Pasta, And Potatoes In Half

Sources
(1) Maternal intake of fat, riboflavin and nicotinamide and the risk of having offspring with congenital heart defects by Smedts HP1, Rakhshandehroo M, Verkleij-Hagoort AC, de Vries JH, Ottenkamp J, Steegers EA, Steegers-Theunissen RP.(PubMed)
(2) Dietary intake of B-vitamins in mothers born a child with a congenital heart defect by Verkleij-Hagoort AC1, de Vries JH, Ursem NT, de Jonge R, Hop WC, Steegers-Theunissen RP.(PubMed)
(3) Maternal intake of fat, riboflavin and nicotinamide and the risk of having offspring with congenital heart defects by Smedts HP1, Rakhshandehroo M, Verkleij-Hagoort AC, de Vries JH, Ottenkamp J, Steegers EA, Steegers-Theunissen RP.(PubMed)

Friday, July 28, 2017

All About Vitamins: Thiamine in Reduced Risk of Vascular Disease

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


Vitamin B1 is one of the members of the vitamin B complex, it is also known as thiamin or thiamine. It's most common form is a colorless chemical compound with the formula C12H17N4OS. It was discovered in 1910 by Umetaro Suzuki in Japan. It is a water soluble vitamin, therefore it can be stored in the body and is required to be taken regularly.

The association of thiamine deficiency among diabetes mellitus without treatment may increased risk of vascular disease involving blood vessels – the arteries and veins of the circulatory system.

According to the Queen Alexandra Hospital, thiamine deficiency may lead to hyperglycaemic-induced damage, affecting vascular disease in promoting cardiovascular risk.

In a study of diabetic patients (26 type 1 and 48 type 2) with and without microalbuminuria and 20 normal healthy control volunteers, researchers found that decrease plasma volumes are associated to patients with diabetes as shown in the scale. Patient with diabetes showed a plasma thiamine concentration decreased 76% in type 1 diabetic patients and 75% in type 2 diabetic patients in compared to normal volunteers.
Diabetic patients also showed an increased urinary excretion of thiamine, which may be a leading cause of thiamine deficiency.

Dr. Thornalley PJ, the lead author said, "low plasma thiamine concentration is prevalent in patients with type 1 and type 2 diabetes, associated with increased thiamine clearance".

Taking altogether, low plasma thiamine concentration in diabetic patients showed to increased risk of vascular disease. Intake of high dose thiamine may be beneficiary to dysfunction of intracellular transport or enzymatic abnormalities in ameliorate the development of vascular dysfunction in inducing stroke.


FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic 
Impact In Rice, Pasta, And Potatoes In Half


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic 
Impact In Rice, Pasta, And Potatoes In Half

Sources
(1) Thiamine deficiency in diabetes mellitus and the impact of thiamine replacement on glucose metabolism and vascular disease by Page GL1, Laight D, Cummings MH.(PubMed)
(2) High prevalence of low plasma thiamine concentration in diabetes linked to a marker of vascular disease by Thornalley PJ1, Babaei-Jadidi R, Al Ali H, Rabbani N, Antonysunil A, Larkin J, Ahmed A, Rayman G, Bodmer CW.(PubMed)
(3) High-dose thiamine improves fatigue after stroke: a report of three cases by Costantini A1, Pala MI, Catalano ML, Notarangelo C, Careddu P.(PubMed)

Thursday, July 27, 2017

All About Vitamins: Thiamine and Parkinson Disease

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


Vitamin B1 is one of the members of the vitamin B complex, it is also known as thiamin or thiamine. It's most common form is a colorless chemical compound with the formula C12H17N4OS. It was discovered in 1910 by Umetaro Suzuki in Japan. It is a water soluble vitamin, therefore it can be stored in the body and is required to be taken regularly.

Thiamine deficiency and dysfunction of thiamine-dependent is found to associate of the development and progression of Parkinson Disease.

According to the Villa Immacolata Clini, administration of high-dose thiamine was effective in reversing motor and nonmotor symptoms, in the patients with PD.

In the recruited 50 patients with PD (33 men and 17 women; mean age, 70.4 ± 12.9 years; mean disease duration, 7.3 ± 6.7 years) with 100 mg of thiamine administered intramuscularly twice a week, without any change to personal therapy, thiamine group showed a significant improvement of symptoms of PD, reduced selective neural damage in the centers and provoking neurodegeneration.
And the re-evaluated after 1 month and then every 3 months during treatment showed a clinical stable improvement over time in all the patients.

Other study suggested that high dose of thiamine as initial treatment may attenuated motor and non-motor deficits of patients with PD.

A recruited three patients with newly diagnosed PD who are not involved in anti-Parkinson's therapy. with Plasmatic thiamine within healthy reference range study, therapy with high doses of thiamine showed a considerable improvement in the motor part of the Unified Parkinson's Disease Rating Scale(UPDRS) ranging from 31.3% to 77.3% which is considered as impotant levels in reduced risk of selective neuronal damage caused by thiamine deficiency due to a dysfunction of thiamine metabolism.

In support to the above analysis, researchers at the Vietnamese American Medical Research Foundation insisted that thiamine supplement can act through a number of non-genomic mechanisms that include protein expression, oxidative stress, inflammation which may link to development of PD.
Taking together, elevated thiamine levels might provide protection against PD, but using high doses can only be prescribed by profession medical doctors.

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic 
Impact In Rice, Pasta, And Potatoes In Half


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic 
Impact In Rice, Pasta, And Potatoes In Half

Sources
(1) Long-Term Treatment with High-Dose Thiamine in Parkinson Disease: An Open-Label Pilot Study by Costantini A1, Pala MI1, Grossi E2, Mondonico S3, Cardelli LE4, Jenner C1, Proietti S1, Colangeli M5, Fancellu R6.(PubMed)
(2) High-dose thiamine as initial treatment for Parkinson's disease by Costantini A1, Pala MI, Compagnoni L, Colangeli M.(PubMed)
(3) Thiamine and Parkinson's disease by Lu'o'ng Kv1, Nguyên LT.(PubMed)

Wednesday, July 26, 2017

All About Vitamins: Thiamine in Reduced Risk of Complications and Treatment of Type II diabetes

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


Vitamin B1 is one of the members of the vitamin B complex, it is also known as thiamin or thiamine. It's most common form is a colorless chemical compound with the formula C12H17N4OS. It was discovered in 1910 by Umetaro Suzuki in Japan. It is a water soluble vitamin, therefore it can be stored in the body and is required to be taken regularly.

Diabetes is a condition caused by insufficient insulin entering the bloodstream in regulating the glucose. The disease is either caused by cells in pancreas dying off or receptor sites clogged up by fat and cholesterol. In some cases, diabetes is also caused by allergic reactions of cells in the immune system.

Thiamine therapy induced a significant change of protein functions in reduced symptoms and complications in patients with Type II diabetes, a study by renowned Institute suggested.

In a double-blind, randomised trial, where 12 hyperglycemic subjects (10 cases of impaired glucose tolerance and 2 new cases of type 2 diabetes mellitus) received both placebo and thiamine capsules (3 × 100 mg/day) for six weeks in a cross-over manner, high dosed vitamin group showed a significant effects on the blood pressure of individuals with hyperglycemia at early stages, and prevention of vascular complications.

Furthermore,  high-dose thiamine supplementation also displayed an impact on glucose tolerance in patients with impaired glucose metabolism.

Dr. Alaei Shahmiri F, the lead researcher on the study said, " supplementation with high-dose thiamine may prevent deterioration in fasting glucose and insulin, and improve glucose tolerance in patients with hyperglycemia. High-dose thiamine supplementation may prevent or slow the progression of hyperglycemia toward diabetes mellitus in individuals with impaired glucose regulation"

Further study also suggested that increase supplement intake may reduce risk thiamine deficiency in the diabetic population and ameliorate the early sign of diabetic kidney disease and improve lipid profile.

Taking altogether, intake of thiamine should have a potential effect in reduced risk of complications and treatment of Type II diabetic patients, pending to further studies.

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic 
Impact In Rice, Pasta, And Potatoes In Half


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic 
Impact In Rice, Pasta, And Potatoes In Half


Sources
(1) Study of Protein Biomarkers of Diabetes Mellitus Type 2 and Therapy with Vitamin B1 by Riaz S1.(PubMed)
(2) The impact of thiamine supplementation on blood pressure, serum lipids and C-reactive protein in individuals with hyperglycemia: a randomised, double-blind cross-over trial by Alaei-Shahmiri F1, Soares MJ2, Zhao Y2, Sherriff J2.(PubMed)

Tuesday, July 25, 2017

All About Vitamins: Thiamine Reduced Risk of Oxidative Stress

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


Vitamin B1 is one of the members of the vitamin B complex, it is also known as thiamin or thiamine. It's most common form is a colorless chemical compound with the formula C12H17N4OS. It was discovered in 1910 by Umetaro Suzuki in Japan. It is a water soluble vitamin, therefore it can be stored in the body and is required to be taken regularly.

Oxidative stress is essentially an imbalance between the production of free radicals and levels of antioxidant, which plays an important role in neutralized the domino's process causes of varies diseases.

Thiamine deficiency induced production of oxidative stress has found to associate to the development of structural lesions, including excitotoxicity, neuroinflammation, blood-brain barrier integrity, mitochondrial integrity, apoptosis, nucleic acid function, the renowned institute study suggested.

According to the joint study lead by the University of Liege, thiamine is essential for normal brain function and its deficiency causes metabolic impairment, specific lesions, oxidative damage and reduced adult hippocampal neurogenesis (AHN). 

In C57BL6/J mice with predator stress for 5 consecutive nights, new born babies showed a significant abnormality of brain lesion of immature neurons but the recovery of this process is promptly reduced when the mice were treated (200mg/kg/day in drinking water for 20days) with thiamine or benfotiamine.

The study also suggested that reverse of brain immature neuron is the result of function of thiamine and thiamine derivative in protected the brain tissues against paraquat-induced oxidative stress.

Furthermore, thiamine compounds function in boosting anti-oxidant cellular defenses of the test subjects may also express through the prevention of stress-induced inhibition of hippocampal neurogenesis and accompanying physiological changes.

Taking together, thiamine and benfotiamine, a derivative of thiamine have played an important role in the development of brain neurons of the new born and prevention of oxidative stress in induction of brain tissues damage.


FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic 
Impact In Rice, Pasta, And Potatoes In Half

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Sources
(1) The impact of oxidative stress in thiamine deficiency: a multifactorial targeting issue by Hazell AS1, Faim S, Wertheimer G, Silva VR, Marques CS.(PubMed)
(2) Thiamine and benfotiamine prevent stress-induced suppression of hippocampal neurogenesis in mice exposed to predation without affecting brain thiamine diphosphate levels by Vignisse J1, Sambon M1, Gorlova A2, Pavlov D2, Caron N1, Malgrange B1, Shevtsova E3, Svistunov A2, Anthony DC4, Markova N5, Bazhenova N6, Coumans B1, Lakaye B1, Wins P1, Strekalova T7, Bettendorff L8.(PubMed)

Monday, July 24, 2017

All About Vitamins: High Dose of Thiamine(Vitamin B1) in Reduced Risk of Neurodegeneration

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


Vitamin B1, also known as thiamin or thiamine, one of the members of the vitamin B complex is a colorless chemical compound with the formula C12H17N4OS., discovered in 1910 by Umetaro Suzuki in Japan. Vitamin B1 is a water soluble vitamin.

Vitamin B1 is found to associate to prevent neurodegeneraive diseases, a recently study conducted by a renown institute suggested.

According to the joint study lead by the Aichi Human Service Center, mice fed with thiamine-restricted diet (thiamine: 0.60 mg/100 g food) died within 30 and 12 days period respectively, induced the dramatically decreased thiamine concentration in the blood and brain, causing acute neurodegeneration.

The development of thiamine metabolism dysfunction syndrome 2(THMD2) exerted anti neurodegeneration probably is the result of thiamine-restricted diet in ameliorate the levels of thiamine (vitamin B1) derivative, namely the thiamine pyrophosphate.

Dr. Suzuki K, the lead author said, "acute neurodegeneration caused by thiamine deficiency is preventable in most parts, and prompt high-dose thiamine administration is critical for the treatment of THMD2".

In fact, reduced thiamine levels can also promote AD-like abnormalities, including memory deficits, neuritic plaques, and hyperphosphorylation of tau. In the study of classical thiamine deficiency and dementia, thiamine deficiency is associate to cognitive deficits and reductions in brain glucose metabolism, affecting function of the thiamine-dependent enzymes.

Researchers at the study also found that drugs or other manipulations interfered with thiamine absorption can cause thiamine deficiency and excess thiamine intake may diminishes AD-like diseases.

In animal models, thiamine deficiency elevates plaque formation, promotes phosphorylation of tau and impairs memory. In contrast, treatment with the thiamine derivative benfotiamine diminishes plaques, decreases phosphorylation of tau and reverses memory deficits..
Therefore, there is no doubt that thiamine deficiency diet may induce the development and progression of neuro degenerative diseases, but doses intake should only be prescribed by medical doctors.


FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic 
Impact In Rice, Pasta, And Potatoes In Half


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic
Impact In Rice, Pasta, And Potatoes In Half

Sources
(1) High-dose thiamine prevents brain lesions and prolongs survival of Slc19a3-deficient mice by Suzuki K1, Yamada K1, Fukuhara Y1, Tsuji A2, Shibata K2, Wakamatsu N1.(PubMed)
(2) Vitamin B1 (thiamine) and dementia by Gibson GE1, Hirsch JA2, Fonzetti P2, Jordan BD2, Cirio RT2, Elder J1.(PubMed)
(3) Abnormal thiamine-dependent processes in Alzheimer's Disease. Lessons from diabetes by Gibson GE1, Hirsch JA, Cirio RT, Jordan BD, Fonzetti P, Elder J.(PubMed)

Friday, July 21, 2017

All About #CurableVitamins: Vitamin B1 Deficiency Associated to the Risk of Alzheimer's disease(AD)

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


Vitamin B1 is one of the members of the vitamin B complex, it is also known as thiamin or thiamine. It's most common form is a colorless chemical compound with the formula C12H17N4OS. It was discovered in 1910 by Umetaro Suzuki in Japan. It is a water soluble vitamin, therefore it can be stored in the body and is required to be taken regularly.

Alzheimer's disease (AD) patients is associated to impaired thiamine metabolites in energy metabolism and activities of thiamine-dependent enzymes (thiamine diphosphate (TDP)) in production of thiamine derivative.

In the recruited 45 AD patients clinically diagnosed and 38 age- and gender-matched control subjects without dementia study, the joint study lead by the Fudan University found that blood TDP contents of AD patients were significantly lower than those in control subjects (79.03 ± 23.24 vs. 127.60 ± 22.65 nmol/L, P<0.0001.

Dr. Pan X, the lead author in the joint study suggested, the imbalance activities of thiamine induced by addition and removal in monophosphatase (TMPase) and thiamine diphosphatase (TDPase) may be directly involved in thiamine and glucose metabolism.

In fact, vitamin deficiencies are causative for AD development, many researchers recommended that they should be tested for early detectable in patient with AD.

Thiamine deficiency (TD) result from inadequate intake, increased requirement, excessive deletion, and chronic alcohol consumption, according to the Shandong University School of Medicine, may play an critical role in central and peripheral nervous systems induced neuro-degenerative diseases, such as Alzheimer's disease(AD), Parkinson's disease (PD), and Huntington's disease (HD), through induced  oxidative stress and impaired natural, regulated, destructive mechanism of the cell in the brain.

There is no doubt that thiamine deficiency is associated to patients with Alzheimer's disease(AD). treatment of high quantity amount of thiamine should only be prescribed by related field specialist.


FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic 
Impact In Rice, Pasta, And Potatoes In Half


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Sources
(1) Enhanced Activities of Blood Thiamine Diphosphatase and Monophosphatase in Alzheimer's Disease by Pan X1,2, Sang S1,2, Fei G1, Jin L1, Liu H2, Wang Z3, Wang H3, Zhong C1,2.(PubMed)
92) Thiamine Deficiency and Neurodegeneration: the Interplay Among Oxidative Stress, Endoplasmic Reticulum Stress, and Autophagy by Liu D1,2, Ke Z3, Luo J4,5.(PubMed)


Thursday, July 20, 2017

All About #CurableVitamins: Vitamin B1 deficiency to Obese and Obesity Complications

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


Vitamin B1 is one of the members of the vitamin B complex, it is also known as thiamin or thiamine. It's most common form is a colorless chemical compound with the formula C12H17N4OS. It was discovered in 1910 by Umetaro Suzuki in Japan. It is a water soluble vitamin, therefore it can be stored in the body and is required to be taken regularly.

Thiamine therapy may be beneficiary for obese patients, a renowned institute study suggested.

Obesity is defined as a medical condition of excess body fat has accumulated overtime, while overweight is a condition of excess body weight relatively to the height. According to the Body Mass Index(BMI), a BMI between 25 to 29.9 is considered over weight, while a BMI of over 30 is an indication of obesity. According to the statistic, 68% of American population are either overweight or obese.

According to the University of the Punjab, obesity frequently have clinical thiamine deficiency with 18% prevalence of clinical thiamine deficiency after gastric bypass surgery and obesity associated diabetes mellitus is a mechanism for development of clinical thiamine deficiency.

Dr. Nath A, the lead author said, " Higher body mass index is a significant risk for clinical thiamine deficiency (P=.007). Clinical thiamine deficiency is common in these individuals and a higher body mass index is an identified risk factor".

In fact, in obese patients undergoing bariatric surgery, blood test before operation showed a significant thiamine deficiency.

In the total of 437 consecutive patients who underwent laparoscopic RYGB or laparoscopic adjustable gastric banding, 303 were included in the study, thiamine deficiency is found to associated with 15.5% of the participants with. male patients presented with greater mean preoperative thiamine levels (3.2 microg /dL) than female patients (2.4 microg/dL).

Taking altogether, intake of vitamin B1 in prescribed doses may reduce risk of thiamine deficiency complications in obese patients.


FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic 
Impact In Rice, Pasta, And Potatoes In Half

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Sources
(1) Prevalence of clinical thiamine deficiency in individuals with medically complicated obesity by Nath A1, Tran T2, Shope TR2, Koch TR3(PubMed)
(2) Preoperative thiamine deficiency in obese population undergoing laparoscopic bariatric surgery by Carrodeguas L1, Kaidar-Person O, Szomstein S, Antozzi P, Rosenthal R.(PubMed)


Wednesday, July 19, 2017

All About #CurableVitamins: Vitamin B1 deficiency in associated to neurodegenerative disease

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


Vitamin B1 is one of the members of the vitamin B complex, it is also known as thiamin or thiamine. It's most common form is a colorless chemical compound with the formula C12H17N4OS. It was discovered in 1910 by Umetaro Suzuki in Japan. It is a water soluble vitamin, therefore it can be stored in the body and is required to be taken regularly.

Thiamine Deficiency induced oxidative and  stress and the natural, regulated, destructive mechanism of the cell in the brain, which are known to contribute to the pathogenesis of various neurodegenerative diseases.

According to the joint study, lead by Shandong University School of Medicine, Thiamine deficiency is kown to cause a cascade of events including mild impairment of oxidative metabolism, neuroinflammation, and neurodegeneration, which are commonly observed in neurodegenerative diseases, such as Alzheimer's disease(AD), Parkinson's disease (PD), and Huntington's disease (HD).

Dr. Liu D, the lead researcher said, " Recent research evidence indicates that TD causes oxidative stress, endoplasmic reticulum (ER) stress, and autophagy in the brain, which are known to contribute to the pathogenesis of various neurodegenerative diseases". 

In mice study of SLC19A3 deficiency, also called thiamine metabolism dysfunction syndrome-2 (THMD2; OMIM 607483), researchers suggested that acute neurodegeneration caused by thiamine deficiency is preventable in most parts and high dose of thiamine prevents brain lesions and prolongs survival of Slc19a3-deficient mice, but reduced doses after treatment should be performed carefully to prevent recurrence after recovery of the disease.

There is no doubt that vitamib B1 deficiency is associated to risk of neuro- degenerative diseases. early detection and vitamin B1 treatment are most effective way to prevent the development of the diseases.


FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic 
Impact In Rice, Pasta, And Potatoes In Half


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Sources
(1) Thiamine Deficiency and Neurodegeneration: the Interplay Among Oxidative Stress, Endoplasmic Reticulum Stress, and Autophagy by Liu D1,2, Ke Z3, Luo J4,5.(PubMed)
(2) High-dose thiamine prevents brain lesions and prolongs survival of Slc19a3-deficient mice by Suzuki K1, Yamada K1, Fukuhara Y1, Tsuji A2, Shibata K2, Wakamatsu N1.(PubMed)

Tuesday, July 18, 2017

All About #CurableVitamins: Vitamin B1 deficiency in associated to Chronic Liver Failure

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


Vitamin B1 is one of the members of the vitamin B complex, it is also known as thiamin or thiamine. It's most common form is a colorless chemical compound with the formula C12H17N4OS. It was discovered in 1910 by Umetaro Suzuki in Japan. It is a water soluble vitamin, therefore it can be stored in the body and is required to be taken regularly.

Patient with chronic liver failure may be beneficiary for intake of prescribed quantity of vitamin B1 supplement depending to the stage of deficiency.

According to the Sanjay Gandhi Post Graduate Institute of Medical Sciences, patients with acute and acute-on-chronic liver failure of non-alcoholic etiology are assocaited to lower levels of blood thiamine.

In a study of 7 acute liver failure patients, blood thiamine showed significant positive correlation with mammillary bodies' volume only at the beginning. but follow-up study done after clinical recovery at 5 weeks., recovery patients showed a reversible restoration of blood thiamine level.

Dr. Butterworth RF said, " End-stage chronic liver failure results in thiamine deficiency caused principally by depletion of liver thiamine store" and "..... thiamine deficiency.... results in consequent increases in brain lactate, oxidative/nitrosative stress,"

Furthermore, in chronic hepatitis B infection, thiamine administration was associated with reduction in aminotransferase levels which is an indication of healthy liver.

Taking together, vitamin B1 is no doubt to associate to patients with chronic liver failure, tratment with vitamin B1 can be only managed by related field specialist.



FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic
Impact In Rice, Pasta, And Potatoes In Half

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer


Sources
(1) Thiamine deficiency related microstructural brain changes in acute and acute-on-chronic liver failure of non-alcoholic etiology by Gupta RK1, Yadav SK, Saraswat VA, Rangan M, Srivastava A, Yadav A, Trivedi R, Yachha SK, Rathore RK.(PubMed)
(2) Thiamine deficiency-related brain dysfunction in chronic liver failure by Butterworth RF1.(PubMed)
(3) Thiamine treatment of chronic hepatitis B infection by Wallace AE1, Weeks WB.(PubMed)

Monday, July 17, 2017

All About #CurableVitamins: Vitamin B1 Reduces Complications and Motility of Patients with Wernicke-Korsakoff syndrome

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


Vitamin B1 is one of the members of the vitamin B complex, it is also known as thiamin or thiamine. It's most common form is a colorless chemical compound with the formula C12H17N4OS. It was discovered in 1910 by Umetaro Suzuki in Japan. It is a water soluble vitamin, therefore it can be stored in the body and is required to be taken regularly.

Intake of prescribed dose of vitamin B1 supplement may reduce risk of complications and mortality with patients with Wernicke-Korsakoff syndrome, a renowned institution study suggested.

Wernicke-Korsakoff syndrome, a thiamine (vitamin B1) deficiency disease may induce potentially debilitating and fatal condition.

According to the Colman Centre for Specialist Rehabilitation Services, the condition is often undiagnosis because of other predisposed factors such as misuse alcohol in interference to the early analysis of the symptoms of diseases.

Dr. Donnelly A, the lead author said, " Wernicke-Korsakoff syndrome ......caused by thiamine (vitamin B1) deficiency in the brain. ......can be treated effectively or prevented completely".

In a total of Sixty-one patients included (51 with WE and 10 with KS). of patients with WE, 78% were men and age at diagnosis was 57 years (interquartile range (IQR): 49-66). with 23% percent fulfilled the classic WE triad in the study, 50% of patients would be expected to die within 8 years of WE episode and main causes of death included serious bacterial infections (44.5%) and cancer (33.3%).

The joint study also emphasize that since the survival rate of of patients with an alcohol-related Wernicke-Korsakoff syndrome is poor, and treatment of alcohol abuse and early diagnosis of thiamine deficiency is a priority for improving clinical outcomes in prevention of of complications such as severe impairment of cognitive function and a craving for alcohol.

There is no doubt that vitamin B1 treatment in early diagnosis of Wernicke-Korsakoff syndrome in a priority in management of patients may be neccessary to reduced complications and motility.


FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic
Impact In Rice, Pasta, And Potatoes In Half

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Sources
(1) Long-Term Mortality of Patients with an Alcohol-Related Wernicke-Korsakoff Syndrome by Sanvisens A1, Zuluaga P1, Fuster D1, Rivas I2, Tor J1, Marcos M3, Chamorro AJ3, Muga R1.(PubMed)
(2)  Wernicke-Korsakoff syndrome: recognition and treatment by Donnelly A1.(PubMed)
(3)Repetitive Transcranial Magnetic Stimulation for Wernicke-Korsakoff Syndrome: A Case Report by Chung SW1, Park SW1, Seo YJ1, Kim JH1, Lee CH2, Lim JY1(PubMed)

Sunday, July 16, 2017

All About #CurableVitamins: Vitamin B1 Anti Inflammatory effects

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


Vitamin B1 is one of the members of the vitamin B complex, it is also known as thiamin or thiamine. It's most common form is a colorless chemical compound with the formula C12H17N4OS. It was discovered in 1910 by Umetaro Suzuki in Japan. It is a water soluble vitamin, therefore it can be stored in the body and is required to be taken regularly.

Recent study suggested that vitamin B1 may process a anti inflammatory properties in binding to pro inflammatory cytokins.
In a diethylnitrosamine (DEN)-induced HCC in Wistar rats, after 12 weeks of treatment study, combination of pure ibuprofen (40 mg/kg) and thiamine possesses the significant chemoprotective effect by restoring the hepatic enzymes and alteration in pro-inflammatory cytokines.

Benfotiamine is a synthetic vitamin B1 (thiamine) found to regulate the activation of microglia, a type of neuroglia cell) in protection against neurodegeneration by inhibiting inflammatory mediators and enhancing anti-inflammatory factor.

Furthermore, according to the Instituto Mexicano del Seguro Social, Mexico City, thiamine (100 mg) used conjuction with other B vitamin in comparison with diclofenac, Diclofenac+B vitamins mixture showed a superior analgesic effect during the assessed period and also a better assessment of the pain relief perception by patients than diclofenac alone.

The analgesic effect of diclofenac by B vitamins in patients also improved the osteoarthritis programmed to total knee arthroplasty, as a clinical model of inflammatory pain.

Moreover, intake of thiamine intake after 7 days also yielded a significant itch relief and combination of cobalamin and thiamine combination significantly relieved both pain and itch through inhibiting inflammatory activity.

The Affiliated Tenth People's Hospital of Tongji University, Shanghai, suggested, "Sixteen patients in the thiamine group achieved ≥ 30% itch reduction;" and " 18 patients achieved ≥ 30% itch reduction and 19 patients obtained ≥ 30% pain reduction in the combination group".

Taking altogether,  vitamin B1 may p[rocess an anti inflammatory effects in reduced pro-inflammatory cytokines expression cause of certain symptoms but quantity intake should be taken with care.

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer


Sources
(1) Thiamine potentiates chemoprotective effects of ibuprofen in DEN induced hepatic cancer via alteration of oxidative stress and inflammatory mechanism by Afzal M1, Kazmi I2, Khan R3, Rana P3, Kumar V4, Al-Abbasi FA5, Zamzami MA5, Anwar F6.(PubMed)
(2) Benfotiamine attenuates inflammatory response in LPS stimulated BV-2 microglia by Bozic I1, Savic D1, Laketa D2, Bjelobaba I1, Milenkovic I3, Pekovic S1, Nedeljkovic N2, Lavrnja I1.(PubMed)
(3) B-vitamin mixture improves the analgesic effect of diclofenac in patients with osteoarthritis: a double blind study by Magaña-Villa MC1, Rocha-González HI, Fernández del Valle-Laisequilla C, Granados-Soto V, Rodríguez-Silverio J, Flores-Murrieta FJ, Carrasco-Portugal MC, Reyes-García JG.(PubMed)

Thursday, July 13, 2017

All About #CurableVitamins: Vitamin B1 in Managing Symptoms and Complications Heart failure

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


Vitamin B1 is one of the members of the vitamin B complex, it is also known as thiamin or thiamine. It's most common form is a colorless chemical compound with the formula C12H17N4OS. It was discovered in 1910 by Umetaro Suzuki in Japan. It is a water soluble vitamin, therefore it can be stored in the body and is required to be taken regularly.

Vitamin B1 or thiamine deficiency is found to associated to high risk of over 50% in heart failure (HF).

According to the cross-sectional study was conducted in 30 HF patients scheduled for regular follow-up visits in the Mayo Heart Failure Clinic, the prevalence of thiamine deficiency in stable HF patients was calculated to be <11.6%.. High doses of thiamine supplementation improved myocardial function and may be become conditionally essential with HF.

In a systematic review of the literature and a meta-analysis to evaluate the prevalence of thiamine deficiency (TD) in HF patients, TD is more common in HF patients than control subjects (odds ratio 2.53, 95% confidence interval 1.65-3.87) and intake of vitamin B1 of these patients are found to associate to improve ejection fraction and reduce symptoms.
Dr. Jain A, the lead author of the study said, " Thiamine deficiency is more prevalent in the HF population, and its supplementation may be beneficial".

Furthermore, intake of thiamine supplement also attenuated symptoms of  increased urine volume and urinary flow rate. in patients with heart failure, through increasing left ventricular ejection fraction and improving functional capacity.

There is no doubt that oral  thiamine supplement may be a potential agent in managing the symptoms and complication of patients with heart failure, but quantity of the vitamin should only be prescribed by your doctor after a blood test.


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer


Sources
(1) Prevalence of thiamine deficiency in a stable heart failure outpatient cohort on standard loop diuretic therapy by Teigen LM1, Twernbold DD2, Miller WL3.(PubMed)
(2) Determining the Role of Thiamine Deficiency in Systolic Heart Failure: A Meta-Analysis and Systematic Review by Jain A1, Mehta R2, Al-Ani M3, Hill JA4, Winchester DE4(PubMed)
(3) Does Long-Term Furosemide Therapy Cause Thiamine Deficiency in Patients with Heart Failure? A Focused Review by Katta N1, Balla S1, Alpert MA2.(PubMed)

Wednesday, July 12, 2017

All About #CurableVitamins: Vitamin B1 in Managing Diabetic Complications

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Vitamin B1 is one of the members of the vitamin B complex, it is also known as thiamin or thiamine. It's most common form is a colorless chemical compound with the formula C12H17N4OS. It was discovered in 1910 by Umetaro Suzuki in Japan. It is a water soluble vitamin, therefore it can be stored in the body and is required to be taken regularly.

Intake of  Vitamin B1( thiamine) may be beneficiary for patients with diabetes in management of diabetic complications

Diabetes is a condition caused by insufficient insulin entering the bloodstream to regulate the glucose. It is either caused by cells in pancreas dying off or receptor sites clogged up by fat and cholesterol. In some cases, diabetes is also caused by allergic reactions of cells in the immune system.

In a total of Fifty-six 6-week-old female mice, divided into seven groups of eight animals, with diabetes induced in fasted mice by using intraperitoneal (IP) injection of alloxan (180 mg/kg), mice treated with thiamine expressed a decreasing blood glucose, lower serum triglyceride (TG), LDL, and total cholesterol (TC) levels.

Dr. Amiri A said, "... and thiamine are potent antidiabetic factors, and that, these compound supplementation possesses hypoglycemic properties and have effect on serum lipid parameters in diabetes mice".

In patients with gene 2 (SLC19A2) mutation causes of permanent neonatal diabetes, intake of thiamine supplementation not only can corrected insulin insufficiency but also reduced complications of anemia or hearing defects.

Furthermore, also in patients with gene 2 (SLC19A2) mutation, thiamine supplementation showed a preventive effect on hematological disorders over a few years in both pediatric subjects, and improved glycaemic control of diabetes mellitus.

Taking altogether, intake of oral supplement of vitamin B1 in patients with diabetes may have a positive effect in managing diabetic complications, but quantity control is necessary to prevent overdoses.
 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer


Sources
(1) Effect of the Zinc Oxide Nanoparticles and Thiamine for the Management of Diabetes in Alloxan-Induced Mice: a Stereological and Biochemical Study by Amiri A1, Dehkordi RAF2, Heidarnejad MS3, Dehkordi MJ4.(PubMed)
(2) Recovered insulin production after thiamine administration in permanent neonatal diabetes mellitus with a novel solute carrier family 19 member 2 (SLC19A2) mutation by Sun C1, Pei Z1, Zhang M1, Sun B2, Yang L1,2, Zhao Z1, Cheng R1, Luo F1.(PubMed)

Tuesday, July 11, 2017

All About #CurableVitamins: The role of Carotenoids in age-related macular degeneration

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Vitamin A, a bi-polar molecule formed by bonds between carbon and hydrogen, is a fat soluble vitamin which can not be stored in the liver but it can be converted from beta-carotene, a powerful antioxidant. The vitamin is best known fir its strong effects in improving vision and enhancing bone growth.

Recent study suggedted that intake  of lutein and zeaxanthin, members of arotenoids, supplements may have a beneficiary effect in reduced risk of age-related macular degeneration, through its antioxidant properties.

Carotenoids, included carotene, are the group of orange pigments phytochemical played an important role as precursors of vitamin A.

Macular degeneration is the small central area of the retina of the eye that controls visual acuity has been reduced due to aging.

In a total of 63,443 women and 38,603 men were followed up, from 1984 until May 31, 2010, in the Nurses' Health Study and from 1986 until January 31, 2010, in the Health Professionals Follow-up Study suggested, higher intake of bioavailable lutein/zeaxanthin is associated with a long-term reduced risk of advanced AMD, as risk of advanced AMD is reduced by about 40% in both women and men.

Intake of carotenoids was also associated with a 25% to 35% lower risk of advanced AMD when comparing extreme quintiles.
Dr. Wise J1. said," diet rich in carotenoids is linked to reduced risk of advanced age related macular degeneration"

In support of the above, Dr. Ma L, the lead researcher said, "Dietary intake of these carotenoids was significantly related with a reduction in risk of late AMD (RR 0·74; 95 % CI 0·57, 0·97); and a statistically significant inverse association was observed between lutein and zeaxanthin intake and neovascular AMD risk (RR 0·68; 95 % CI 0·51, 0·92)" in review of the five databases up to April 2010.

In fact, Increased dietary intake of or supplementation with lutein and zeaxanthin was also found to increase plasma levels,  associated with macular pigment optical density, but optimal dose of lutein and zeaxanthin for the prevention or treatment of AMD has not yet been defined.

taking altogether, Carotenoids may be a potential supplement for reduecd risk and treatment of age-related macular degeneration, but quantity intake should be consulted with specific profession as toxicity has been recorded in case of overdoses.




Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Sources
(1) Intakes of Lutein, Zeaxanthin, and Other Carotenoids and Age-Related Macular DegenerationDuring 2 Decades of Prospective Follow-up by Wu J1, Cho E2, Willett WC3, Sastry SM4, Schaumberg DA5.(PubMed)
(2) Lutein and zeaxanthin intake and the risk of age-related macular degeneration: a systematic review and meta-analysis by Ma L1, Dou HL, Wu YQ, Huang YM, Huang YB, Xu XR, Zou ZY, Lin XM.(PubMed)
(3) Lutein and zeaxanthin for macular degeneration by Zhao L1, Sweet BV.(PubMed)

Monday, July 10, 2017

All About #CurableVitamins: The role of Carotenoids in Anti inflammatory activities

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Vitamin A, a bi-polar molecule formed by bonds between carbon and hydrogen, is a fat soluble vitamin which can not be stored in the liver but it can be converted from beta-carotene, a powerful antioxidant. The vitamin is best known fir its strong effects in improving vision and enhancing bone growth.

Carotenoids, included carotene, are the group of orange pigments phytochemical played an important role as precursors of vitamin A.

Recent study suggested that dietary carotenoids is found to inhibited inflammatory cytokines in reduced risk of chronic diseases, such as CVD.
According to the joint study lead by the University of Bari, the result of inflammatory effect of carotenoids probably due to their free radicals scavenger properties and improved low-density lipoprotein cholesterol resistance to oxidation.
t
Dr Krinsky NI and Dr. Johnson EJ., in the study of health effects of carotenoid actions, said," the beneficial effects of carotenoids are thought to be due to their role as antioxidants. beta-Carotene may have added benefits due its ability to be converted to vitamin A. Additionally, lutein and zeaxanthin may be protective in eye disease because they absorb damaging blue light that enters the eye".

In the measured plasma from 134 patients with stable angina (SA) and 59 patients with acute coronary syndrome, the carotenoid derivative showed a inverse correlation with inflammatory cytokine IL-6 in SA patients at baseline (r = -0.366, p < 0.001) and follow-up (r = -0.546, p < 0.001).
Furthermore, in patient with schizophrenia, carotenoids inhibited inflammation and oxidative stress in regualted the function of pro-inflammatory cytokines involved central nervous development and proper functioning of neural networks and neurotransmitters.

Due to benefits of the precursor, instead of intake of vitamin A supplement, many researchers recommend that paients with vitamin A deficiency should increase intake of fruits and vegetables with rich of vitamin A.

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer


Sources
(1) Dietary intake of carotenoids and their antioxidant and anti-inflammatory effects in cardiovascular care by Ciccone MM1, Cortese F1, Gesualdo M1, Carbonara S1, Zito A1, Ricci G1, De Pascalis F1, Scicchitano P1, Riccioni G2.(PubMed)
(2) Carotenoid actions and their relation to health and disease by Krinsky NI1, Johnson EJ.(PubMed)
(3) Lutein exerts anti-inflammatory effects in patients with coronary artery disease by Chung RWS1, Leanderson P2, Lundberg AK3, Jonasson L3.(PubMed)
94) Antioxidant and anti-inflammatory nutrient status, supplementation, and mechanisms in patients with schizophrenia by Mitra S1, Natarajan R1, Ziedonis D1, Fan X2.(PubMed)

Saturday, July 8, 2017

All About Vitamins: Vitamin A Interactions

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Vitamin A, a bi-polar molecule formed by bonds between carbon and hydrogen, is a fat soluble vitamin which can not be stored in the liver but it can be converted from beta-carotene, a powerful antioxidant. The vitamin is best known fir its strong effects in improving vision and enhancing bone growth.

All-trans retinoic acid (ATRA) played essential roles in the normal biological processes and the treatment of cancer and skin diseases may cause potential interaction with lysozyme, tyrosine, tryptophan and many antioxidants, such as curcumin (Cur), vitamin C (VC) and gallic acid (GA), according to the Tongji University study.

Coadministered with ketoconazole and liarozole, atRA expressed favorably in regulating the cell cycle, and the treatment of other cancers against therapy resistance, inhibitors of atRA metabolism.
Dr. Jing J. the lead author said, "It accurately predicted the changes in atRA exposure after continuous dosing and when coadministered with ketoconazole and liarozole. The developed model will be useful in interpretation of atRA disposition and efficacy, design of novel dosing strategies, and development of next-generation atRA metabolism inhibitors".

In B-cell chronic lymphocytic leukemia cells, combination of ATRA and rituximab showed synergistic induction of apoptosis compared to untreated CLL cells as a negative control.

Taking altogether, Intake and Vitamin A may increase the efficacy of other vitamins and herbs in reduced production of free radicals. When used combination with other conventional medicines, vitamin A induced the effectiveness and expression of medicines involved.



Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer


Sources
(1) Interaction of retinoic acid radical cation with lysozyme and antioxidants: laser flash photolysis study in microemulsion by Li K1, Wang M, Wang T, Sun D, Zhu R, Sun X, Wu X, Wang SL.(PubMed)
(2) Physiologically Based Pharmacokinetic Model of All-trans-Retinoic Acid with Application to Cancer Populations and Drug Interactions by Jing J1, Nelson C1, Paik J1, Shirasaka Y1, Amory JK1, Isoherranen N2.(PubMed)
(3) Synergistic induction of apoptosis in B-cell chronic lymphocytic leukemia cells after treatment with all-trans retinoic acid in combination with interleukin-21 and rituximab by Abbaszadeh-Goudarzi K1, Shokri F2, Hosseini M3, Jadidi-Niaragh F2, Ghalamfarsa G4, Saboor-Yaraghi AA5.(PubMed).

Friday, July 7, 2017

All About Vitamins: Vitamin A and Stroke

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Vitamin A, a bi-polar molecule formed by bonds between carbon and hydrogen, is a fat soluble vitamin which can not be stored in the liver but it can be converted from beta-carotene, a powerful antioxidant. The vitamin is best known fir its strong effects in improving vision and enhancing bone growth.

Retinoic acid (RA), a derivative of vitamin A plays crucial roles during vertebrate organogenesis in participated in blood-brain barrier (BBB) development in maintaining a stabilized milieu for synaptic and neuronal functions to prevent ischemic stroke.

Stroke is caused by uncontrolled diet that is high in saturated and trans fats resulting in cholesterol build up in the arteries and high blood pressure. In other words, if cholesterol building up in the arteries is blocking the circulation of blood in any part of the body causing oxygen not to be delivered to the brain, resulting in some cells in the brain to die off and are unable reproduce, then we have stroke. Other strokes happen when a blood vessel in the brain ruptures causing the cells in your brain to be deprived of oxygen in your blood, they die and never come back.

In a total of 60 male Kunming mice randomly divided into two groups, i.e. pretreatment (n=40) and post-treatment (n=20) groups, ATRA administered before transient middle cerebral artery occlusion (tMCAO)for 7 days mice group failed to protect brain against ischemic damage and ATRA administered mice group immediately following tMCAO induced cerebral protective effect 24 hours after tMCAO.

In cerebral ischemia-reperfusion injury mice, Dr. said, "Electroacupuncture (EA) decreased the infarct volume, promoted neurological functional recovery and increased the RA in transferred DNA information into mRNA and protein expression, compared with the model group" and "....promoting neurological functional recovery by modulating RA expression in the post-ischemic brain is one of the mechanisms by which EA can be effective in the treatment of ischemic stroke."

Please note the Retinoic acid receptor can be activated by both all-trans retinoic acid and 9-cis retinal acid.

Vitamin A deficiency may interfere with the function of stabilized milieu for synaptic and neuronal functions to induce stroke, as well as reduced cerebral protection against ischemic damage.


Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Sources
(1) Retinoic acid ameliorates blood-brain barrier disruption following ischemic stroke in rats by Kong L1, Wang Y1, Wang XJ1, Wang XT1, Zhao Y1, Wang LM2, Chen ZY3.(PubMed)
(2) [Effect of all-trans retinoic acid on cerebral ischemia injury and regulatory T cell accounts in stroke mice].[Article in Chinese]by Yang Y1, Wang S1, Jia W1, Dong H1, Wang C1.(PubMed)
(3) Electroacupuncture promotes neurological functional recovery via the retinoic acid signaling pathway in rats following cerebral ischemia-reperfusion injury by Hong J1, Wu G, Zou Y, Tao J, Chen L.(PubMed)

Thursday, July 6, 2017

All About Vitamins: Vitamin A and Lung cancer

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Vitamin A, a bi-polar molecule formed by bonds between carbon and hydrogen, is a fat soluble vitamin which can not be stored in the liver but it can be converted from beta-carotene, a powerful antioxidant. The vitamin is best known fir its strong effects in improving vision and enhancing bone growth.

Provitamin A carotenoid β-cryptoxanthin (BCX) supplement may be associate to lower risk and treatment of lung cancer. 
According to Tufts University, BCX significantly reduced the multiplicity of the NNK-induced lung tumor by 52% to 63% compared with the NNK-treated mice without BCX supplementation, in the study of 4-[methyl nitrosamino]-1-[3-pyridyl]-1-butanone (NNK)-induced lung tumorigenesis in A/J mice.

Lung cancer is a condition of the abnormal growth of the cells in the lung's tissue. Most common form of primary lung cancers are derived from epithelial cells. In Us, Lung cancer is the leading cause of cancer deaths, causing 158,683 people deaths, including 88,329 men and 70,354 women, according to 2007 statistic.

Dr. Iskandar AR, the lead researchers said, "The activities of BCX were significantly attenuated by activators of α7-nAChR/PI3K(immune system) signaling or by overexpression of constitutively active PI3K(cell cycle division). Collectively, the results suggest that BCX inhibits".

Other researchers suggested that over expression of lung cancer tissues may be also associate to the abnormal function of retinoid metabolism. caused by changes in the expression of 23 genes that regulate retinoid metabolism and signaling in non-small-cell lung cancer tumors compared to adjacent normal tissues.

The random-effect model used to estimate the relative risk (RR) and their 95% CI in a total of 19 studies comprising 10,261 lung cancer cases met the inclusion criteria, insisted higher category of dietary β-carotene intake could reduce lung cancer risk (0.768 (0.675-0.874)).
The associations were also significant in American and Asian populations. In conclusions, higher category of dietary β-carotene and vitamin A intakes could reduce the risk of lung cancer.

In fact, risk of lung cancer is increased for smokers as the result of depletion of vitamin A in the body induced imbalance of protein expression in the retinoic acid receptor.

Taking altogether, dietary vitamin A exposure,  change life style are associate to reduced risk of lund cancer while vitamin A deficiency is increased risk of the diseases.


Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Sources
(1) β-Cryptoxanthin Reduced Lung Tumor Multiplicity and Inhibited Lung Cancer Cell Motility by Downregulating Nicotinic Acetylcholine Receptor α7 Signaling by Iskandar AR1, Miao B1, Li X1, Hu KQ1, Liu C1, Wang XD2.(PubMed)
(2) [Abnormal expression of genes that regulate retinoid metabolism and signaling in non-small-cell lung cancer].[Article in Russian]by Kuznetsova ES1, Zinovieva OL1, Oparina NY1, Prokofjeva MM1, Spirin PV1, Favorskaya IA2, Zborovskaya IB2, Lisitsyn NA1, Prassolov VS1, Mashkova TD1,3.(PubMed)
(3) Association of Dietary Vitamin A and β-Carotene Intake with the Risk of Lung Cancer: A Meta-Analysis of 19 Publications by Yu N1, Su X2, Wang Z3, Dai B4, Kang J5.(PubMed)
(4) Vitamin A depletion induced by cigarette smoke is associated with an increase in lung cancer-related markers in rats by Xue Y1, Harris E2, Wang W3, Baybutt RC4,5.(PubMed)

Wednesday, July 5, 2017

All About Vitamins: Vitamin A and Complications of Coronary Artery Disease

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Vitamin A, a bi-polar molecule formed by bonds between carbon and hydrogen, is a fat soluble vitamin which can not be stored in the liver but it can be converted from beta-carotene, a powerful antioxidant. The vitamin is best known fir its strong effects in improving vision and enhancing bone growth.

Low level of serum of Retinoic acid (RA) is found to associate to the risk of the development of Coronary Artery Disease and its complications in patients with such disease, according to Gaziosmanpaşa University.

And serum of Retinoic acid (RA) in patient with coronary Artery Disease may be associate to the increased risk of morality, the measured serum RA concentrations in 1499 patients with angiographically confirmed coronary artery disease(mean age, 61 years; male, 67%) recruited from October 2008 and December 2011 in the Guangdong Coronary Artery Disease Cohort suggested.

Coronary Artery Disease is a condition of heart muscle become hardened and narrowed of that can increased risk of blood oxygen levels and blood flow cause of heart diseases.

Some researchers in the study of the risk of coronary Artery Disease and its complications suggested maintaining serum vitamin A levels less than 30 μg/dL or greater than 80 μg/dL levels may be the best way to prevent risk of all-cause mortality and coronary artery disease-related mortality.

Dr. Min KB,and Dr. Min JY. said, "Comparing the normal range of serum vitamin A, the hazard ratio with deficient serum vitamin A was 2.9 (95% CI 2.0-4.3) for all-cause mortality, 2.1 (95% CI 1.1-4.1) for cardiovascular-related mortality and 2.5 (95% CI 1.2-5.3) for coronary artery disease-related mortality" and " Excessive serum vitamin A was associated with a 1.2-fold (95% CI 1.1-1.4) increased risk of all-cause mortality, a 1.4-fold (95% CI 1.2-1.8) increased risk of cardiovascular-related mortality, and a 1.5-fold (95% CI 1.2-2.0) increased risk of coronary artery disease-related mortality".

Taking altogether, the risk of developed Coronary Artery Disease and induced complications of patients with such diseases may be a result of vitamin A deficiency or  a significant high levels of plasma of vitamin A in the body. Therefore, intake of large amount of vitamin A supplement can only  be prescribed by medical doctors.

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer


Sources
(1) The association of plasma vitamin A and E levels with coronary collateral circulation by Söğüt E1, Kadı H2, Karayakalı M2, Mertoğlu C3(PubMed)
(2) Association of Serum Retinoic Acid With Risk of Mortality in Patients With Coronary Artery Disease by Liu Y1, Chen H1, Mu D1, Li D1, Zhong Y1, Jiang N1, Zhang Y1, Xia M2.(PubMed)
(3) Relation of serum vitamin A levels to all-cause and cause-specific mortality among older adults in the NHANES III population by Min KB1, Min JY2.(PubMed)
(

Monday, July 3, 2017

All About Vitamins: Vitamin A Antiproliferative Effects

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Vitamin A, a bi-polar molecule formed by bonds between carbon and hydrogen, is a fat soluble vitamin which can not be stored in the liver but it can be converted from beta-carotene, a powerful antioxidant. The vitamin is best known fir its strong effects in improving vision and enhancing bone growth.

Novel all-trans-retinoic acid (ATRA), a derivative of vitamin A, according to the School of Pharmacy, Zunyi Medical University, efficiently triggered cell cycle arrest and induced apoptosis in cancer cell lines MKN-45 and BGC-823 cells. 
The Antiproliferative Effects is a result of increase the expression levels in regulated the retinoic acid receptor.

In human thyroid carcinoma cells, the derivative also increased its antiproliferative properties through liposomes, a artificial formation which protects (ATRA) against photodegradation.

The joint study of the effect of The NSCLC cell lines A549, NCI-H460 and HCC827 treated with ATRA, lead by the University of Freiburg Medical Center, ingestion of ATRA alone reduced cellular proliferation by at least 50 %, particular in the A549, lung cancer cell line.

In fact, the antiproliferative effects of all-trans-retinoic acid (ATRA) has shown a significant anti-proliferative and anti-migration effect upon melanoma cells without inducing toxicity, when used conjunction with endoxifen.

Taking altogether, vitamin A derivative may be a potential agent for treatment of varies cancers, but further studies in human trial are necessary to ensure the safety of the future application.

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Sources
(1)Synthesis and Antiproliferative Activity of Novel All-Trans-Retinoic Acid-Podophyllotoxin Conjugate towards Human Gastric Cancer Cells by Zhang L1, Wang J2, Liu L3, Zheng C4, Wang Y5.(PubMed)
(2) Anticancer activity of all-trans retinoic acid-loaded liposomes on human thyroid carcinoma cells by Cristiano MC1, Cosco D2, Celia C3, Tudose A4, Mare R1, Paolino D5, Fresta M6.(PubMed)
(3) Epigenetic priming of non-small cell lung cancer cell lines to the antiproliferative and differentiating effects of all-trans retinoic acid by Greve G1,2, Schiffmann I3,4, Lübbert M5,6.(PubMed)
(4) The combination of the antiestrogen endoxifen with all-trans-retinoic acid has anti-proliferative and anti-migration effects on melanoma cells without inducing significant toxicity in non-neoplasic cells by Ribeiro MP1, Silva FS, Paixão J, Santos AE, Custódio JB.(PubMed)

Sunday, July 2, 2017

All About Vitamins: Vitamin A Immunomodulatory Effects

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Vitamin A, a bi-polar molecule formed by bonds between carbon and hydrogen, is a fat soluble vitamin which can not be stored in the liver but it can be converted from beta-carotene, a powerful antioxidant. The vitamin is best known fir its strong effects in improving vision and enhancing bone growth.

Vitamin A is found to associate to immune defence against the invasion of microorganisms, such as virus, through activation of inflammatory effects. According to the joint study lead by the Turku University Hospital, Detection of viruses decreased by age. Higher vitamin A levels showed borderline significance with less viral detection (P = 0.056).
Inflammation (from Latin inflammatio) is an immune response biological body tissues against harmful stimuli, such as pathogens, damaged cells, or irritants, ..

In Human Monocytes during Infection, vitamin A showed an unexpected ability to counteract the pathogen-induced transcriptional responses, through immunomodulatory activity, deepening on the inflammatory stimulus.

In a total of 35 patients with chronic immune thrombocytopenia, who failed with standard dose corticosteroids and/or splenectomy, immunomodulatory therapy with all-trans retinoid acid (ATRA) expressed a significant changes of Treg cells to induce response.

In fact, all-trans retinoid acid (ATRA) exhibited Immunomodulatory Effects through inhibited pro inflammatory cytokine production.

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer


Sources
(1) The relationship of serum vitamins A, D, E and LL-37 levels with allergic status, tonsillar virus detection and immune response by Elenius V1, Palomares O2,3, Waris M4, Turunen R1, Puhakka T5,6, Rückert B2, Vuorinen T4, Allander T7, Vahlberg T8, Akdis M2, Camargo CA Jr9, Akdis CA2, Jartti T1.(PubMed)
(2) Differential Effects of Vitamins A and D on the Transcriptional Landscape of Human Monocytes during Infection by Klassert TE1, Bräuer J1, Hölzer M2, Stock M1, Riege K2, Zubiría-Barrera C1, Müller MM1,3, Rummler S4, Skerka C5, Marz M2, Slevogt H1.(PubMed)
(3) Efficacy of immunomodulatory therapy with all-trans retinoid acid in adult patients with chronic immune thrombocytopenia by Dai L1, Zhang R1, Wang Z2, He Y3, Bai X1, Zhu M1, Yu Z1, Ruan CG1.(PubMed)
(4) Vitamin A induces inhibitory histone methylation modifications and down-regulates trained immunity in human monocytes by Arts RJ1, Blok BA1, van Crevel R1, Joosten LA1, Aaby P1, Benn CS1, Netea MG2.(PubMed)