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Vitamin B1 is one of the members of the vitamin B complex, it is also known as thiamin or thiamine. It's most common form is a colorless chemical compound with the formula C12H17N4OS. It was discovered in 1910 by Umetaro Suzuki in Japan. It is a water soluble vitamin, therefore it can be stored in the body and is required to be taken regularly.
Patient with chronic liver failure may be beneficiary for intake of prescribed quantity of vitamin B1 supplement depending to the stage of deficiency.
According to the Sanjay Gandhi Post Graduate Institute of Medical Sciences, patients with acute and acute-on-chronic liver failure of non-alcoholic etiology are assocaited to lower levels of blood thiamine.
Furthermore, in chronic hepatitis B infection, thiamine administration was associated with reduction in aminotransferase levels which is an indication of healthy liver.
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(1) Thiamine deficiency related microstructural brain changes in acute and acute-on-chronic liver failure of non-alcoholic etiology by Gupta RK1, Yadav SK, Saraswat VA, Rangan M, Srivastava A, Yadav A, Trivedi R, Yachha SK, Rathore RK.(PubMed)
(2) Thiamine deficiency-related brain dysfunction in chronic liver failure by Butterworth RF1.(PubMed)
(3) Thiamine treatment of chronic hepatitis B infection by Wallace AE1, Weeks WB.(PubMed)