Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Vitamin A, a bi-polar molecule formed by bonds between carbon and hydrogen, is a fat soluble vitamin which can not be stored in the liver but it can be converted from beta-carotene, a powerful antioxidant. The vitamin is best known fir its strong effects in improving vision and enhancing bone growth.
Retinoic acid (RA), a derivative of vitamin A plays crucial roles during vertebrate organogenesis in participated in blood-brain barrier (BBB) development in maintaining a stabilized milieu for synaptic and neuronal functions to prevent ischemic stroke.
In a total of 60 male Kunming mice randomly divided into two groups, i.e. pretreatment (n=40) and post-treatment (n=20) groups, ATRA administered before transient middle cerebral artery occlusion (tMCAO)for 7 days mice group failed to protect brain against ischemic damage and ATRA administered mice group immediately following tMCAO induced cerebral protective effect 24 hours after tMCAO.
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(1) Retinoic acid ameliorates blood-brain barrier disruption following ischemic stroke in rats by Kong L1, Wang Y1, Wang XJ1, Wang XT1, Zhao Y1, Wang LM2, Chen ZY3.(PubMed)
(2) [Effect of all-trans retinoic acid on cerebral ischemia injury and regulatory T cell accounts in stroke mice].[Article in Chinese]by Yang Y1, Wang S1, Jia W1, Dong H1, Wang C1.(PubMed)
(3) Electroacupuncture promotes neurological functional recovery via the retinoic acid signaling pathway in rats following cerebral ischemia-reperfusion injury by Hong J1, Wu G, Zou Y, Tao J, Chen L.(PubMed)