Socrates Said," Let foods be your medicine and let medicine be your foods". Let us all practice the values of the past wisdom to build a letter living and living health while we enjoy the delicious drinks

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Saturday, July 23, 2022

Omega 3 Fatty Acids Suppress Cancer Cachexia in Patients with Pancreatic Cancer

The pancreas is an oblong flattened gland in the digestive and endocrine system located in the abdomen. By secreting pancreatic juice to the small intestine, the pancreas helps to break down carbohydrates, proteins, and lipids.


Traditional Chinese medicine views the pancreas, as a vital organ responsible for the absorption of foods' qi and nutrients before passing them to other organs to nourish our body.


More precisely, the functions of the pancreas including
* Production of enzymes digest fat, protein, and
carbohydrates.

* production of juices combined with juices from the intestines helps to do the job of breaking down protein, carbohydrates, and fat, therefore, it plays an important role in maintaining good health.

* Production of insulin, which is important in regulating the amount of sugar or glucose in the blood.

Pancreatic cancer is a chronic condition characterized by cell growth irregularly in the tissues of the pancreas.

According to statistics, every year, approximately, over 55,000 adults in the United States are diagnosed with pancreatic cancer, accounting for 3% of all cancers and 7% of all cancer deaths.

The survival rate of pancreatic cancer even diagnosed early is very low compared to other types of cancer. The 5-year survival rate at stage IA pancreatic cancer is only14%.

Researchers do not know what causes pancreatic cancer. They don't even know why people with the same health conditions in the same family, are susceptible to pancreatic cancer, while others do not.

The most common risk factors of pancreatic cancer are similar to those of common cancers, including age, family history, gender, ethnicity, smoking, being overweight or obese, and certain medical conditions such as diabetes.

Cancer cachexia is a condition a multifactorial syndrome associated with an ongoing loss of skeletal muscle mass.

Omega-3 fatty acids are phytochemicals in the class of lipids, found abundantly in deepsea fisk, dark-green leafy vegetables, grains, legumes, nuts, etc.


The three main components of Omega-3 fatty acids are alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).

On finding a potential phytochemical for the treatment of cancer, researchers examined the effects of omega-3 fatty acids in patients with pancreatic and bile duct cancer.

According to the administration of Racol®, an enteral nutrient formulated with omega-3 fatty acids to patients with unresectable pancreatic and bile duct cancer at 4 and 8 weeks after, pre-administration and administration showed a strong activity that increases skeletal muscle mass at both 4 and 8 weeks.


In other words, Omega-3 fatty acid supplementation protects the skeletal muscle mass associated with cancer cachexia in patients with unresectable pancreatic cancer and may improve cancer.


Taken altogether, Omega-3 fatty acids found abundantly in fish oil and plant oil may be considered a functional food for the reduction of cancer cachexia in patients with pancreatic cancer, pending the confirmation of the larger sample size and multicenter human study.

Intake of Omega-3 fatty acids in the form of supplements should be taken with extreme care to prevent overdose and acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional's Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Omega-3 Fatty Acids Prevent Early Pancreatic Carcinogenesis via Repression of the AKT Pathway by Ding Y1, Mullapudi B2, Torres C3, Mascariñas E4,5, Mancinelli G6, Diaz AM7, McKinney R8, Barron M9, Schultz M10,11, Heiferman M12, Wojtanek M13, Adrian K14, DeCant B15,16, Rao S17, Ouellette M18, Tsao MS19, Bentrem DJ20, Grippo PJ. (PubMed)
(2) Effects of ω-3 Fatty Acid Supplementation in Patients with Bile Duct or Pancreatic Cancer Undergoing Chemotherapy by Abe K1, Uwagawa T2, Haruki K2, Takano Y2, Onda S2, Sakamoto T2, Gocho T2, Yanaga K. (PubMed)

Saturday, July 9, 2022

Phytochemicals Omega-3 Fatty Acids, the Healthy Fat for the Treatment of Myocardial Infarction

Stroke is the third leading cause of death. Approximately 1/4 of all stroke victims die as a direct result of the stroke or its complications.

Stroke is caused by the accumulation of cholesterol and other substances that build up the arterial walls.

In other words, if cholesterol building up in the arteries is blocking the circulation of blood in any part of the body causing oxygen not to be delivered to the brain, leading to the death of some cells in the brain.

According to the statistics, every year, more than 790,000 people suffer a stroke, 600,000 of these are first attacks, and 185,000 are recurrent attacks. Most cases of stroke occur in people over the age of 65.

Myocardial infarction (MI) is a medical condition known as a heart attack caused by the blood flow decreasing or stopping in a part of the heart, leading to damage to the heart muscle.

In other words, myocardial infarction (MI) occurs due to the imbalance in oxygen supply and demand caused by plaque rupture with thrombus formation in an artery, leading to reduced blood flow to the heart.

Prompt treatment can minimize brain damage and potential post-disease complications.


The most common symptoms of MI are pressure, tightness, pain, or a squeezing or aching sensation in your chest, digestive discomforts such as nausea, indigestion, heartburn, abdominal pain, shortness of breath, and dizziness.

Conventionally, the treatment of myocardial infarction is focused to reduce the damage to the heart muscle accomplished through medical or mechanical means.


Omega-3 fatty acids are phytochemicals in the class of lipids, found abundantly in deepsea fisk, dark-green leafy vegetables, grains, legumes, nuts, etc.


The three main components of Omega-3 fatty acids are alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).

On finding a potential phytochemical for the treatment of post-stroke, researchers examined the omega-3 eicosapentaenoic acid (EPA) EPA the infarct-limiting effect on experimental models.

The observational study was conducted in 100 patients with a reperfused anterior ST-elevation myocardial infarction (STEMI), at hospital admission who are quantified by gas-chromatography the red blood cell proportions of AA, EPA, and the AA: EPA ratio, a valid surrogate for cardiomyocyte membrane content.

According to the results of the tested analysis,* AA:EPA ratio directly related to acute infarct size (coefficient [95% CI]: 6.19 [1.68 to 10.69], P = 0.008) and inversely to long-term cardiac function (left ventricular ejection fraction [LVEF]) (coefficient [95% CI]: − 4.02 [− 7.15 to − 0.89], P = 0.012), comapred to uintreated control.

* EPA inversely related to acute infarct size (coefficient [95% CI]: − 6.58; [− 11.46 to − 1.70]; P = 0.009), while a direct association with LVEF at follow-up (coefficient [95% CI]: 3.67 [0.25 to 7.08]; P = 0.036) was observed.


In other words, both applications of omega 3 fatty acids demonstrated protective activity to preserve the neuron against damage immediately after the incidence of stroke.
Additionally, researchers also found, " A low AA: EPA ratio in red blood cells at the time of STEMI is associated with smaller acute infarct size and preserved long-term ventricular function".

Collectively, they said, "Our results are consistent with prior work in experimental models and add to the notion of omega-3 fatty acids as a healthy fat".

Taken altogether, Omega-3 fatty acids found abundantly in fish oil and plant oil may be considered a functional food for the treatment of myocardial infarction, pending the confirmation of the larger sample size and multicenter human study.

Intake of Omega-3 fatty acids in the form of supplements should be taken with extreme care to prevent overdose and acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals' Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Nutritional preconditioning by marine omega-3 fatty acids in patients with ST-segment elevation myocardial infarction: A METOCARD-CNIC trial substudy by Sala-Vila A1, Fernández-Jiménez R2, Pizarro G3, Calvo C1, García-Ruiz JM4, Fernández-Friera L5, Rodriguez MD4, Escalera N4, Palazuelos J6, Macías A4, Pérez-Asenjo B4, Fernández-Ortiz A2, Ros E1, Fuster V7, Ibáñez B. (PubMed)

Sunday, July 3, 2022

Beta-Sitosterol Protects the Pancreatic Islets functioning Against the Risk of Type 2 Diabetes

The pancreas is an oblong flattened gland in the digestive and endocrine system located in the abdomen. By secreting pancreatic juice to the small intestine, the pancreas helps to break down carbohydrates, proteins, and lipids.

Traditional Chinese medicine views the pancreas, as a vital organ responsible for the absorption of foods' qi and nutrients before passing them to other organs to nourish our body.

More precisely, the functions of the pancreas including the
* Production of enzymes digest fat, protein, and
carbohydrates.

* Production of juices combined with juices from the intestines to break down protein, carbohydrates, and fat, therefore, it plays an important role in maintaining good health.

* Production of insulin, which is important in regulating the amount of sugar or glucose in the blood.

Pancreatic islets are groups of hormones producing cells, including insulin and glucagon, that work together to maintain the proper level of sugar (glucose) in the blood.

Profound distortion of islet organization in the pancreas has been found to induce account abnormal secretory behavior of the glucagon-secreting A cells in insulin-dependent juvenile-onset diabetes.

Type 1 diabetes, also known as juvenile diabetes or insulin-dependent diabetes, is the most common form of diabetes found in children and is a condition in which the pancreas does not produce any insulin. The most common form of type 1 diabetes is caused by genetic mutation and some viruses.

As of today, there is no cure for type 1 diabetes. Treatment is focusing on managing blood sugar levels with insulin injection, diet, and lifestyle change.

According to statistics, diabetes is one of the most common diseases in the US. Approximately 10% or 29.1 million people in the United States have diabetes, accompanied by 8.1 million that are undiagnosed and unaware of their condition.

About 1.4 million new cases of diabetes are diagnosed in the United States every year. More than one in every 10 adults who are 20 years or older has diabetes.


Beta-Sitosterol is a phytochemical in the class of Phytosterols, belongings to the group of Lipids, found abundantly in avocados, rice bran, wheat germ, corn oils, fennel, peanuts, soybeans, hawthorn, basil, and buckwheat. etc.

In finding a potential phytochemical for the prevention and treatment of infectious diseases, researchers elucidated the anti-diabetic effects of the extract of A. tenuifolia underground parts and β-sitosterol on rat pancreatic islets.

According to the results of the analysis,* The root extract of the plant and compound β-sitosterol isolated from the root extracts showed moderate α-amylase inhibitory activity.

* Furthermore, the herb root extract was able to increase the secretion of insulin in high concentrations (10 mg/mL) and improved the cell viability with no toxicity in all doses.

* The herbal extract could reduce the levels of reactive oxygen species (ROS) and lipid peroxidation (LPO) associated with the onset of oxidative stress in orchestrating damage to the pancreatic islets.

* Moreover, the plant extract also significantly decreased the enzyme activity associated with pro-apoptotic expression by increasing the antioxidant capacity of the isolated cells.


In other words, all compounds found in the extract work synergistically to protect the pancreatic islets by inhibiting all parameters involved in pancreatic damage, particularly, the compound β-sitosterol

Taken altogether, beta-Sitosterol combined with other phytochemicals found in A. tenuifolia underground parts may be considered a supplement for the protection of pancreatic islets-induced diabetes, pending the confirmation of the larger sample size and multicenter human study.

Intake of beta-Sitosterol in the form of supplements should be taken with extreme care to prevent overdose and acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional's Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Investigation of β-Sitosterol and Prangol Extracted from Achillea Tenoifolia Along with Whole Root Extract on Isolated Rat Pancreatic Islets by Rahimifard M1,2, Manayi A3,2, Baeeri M1, Gholami M4, Saeidnia S3, Abdollahi M. (PubMed)