The liver is the largest internal organ found in the human which plays an essential role in filtering the blood from the digestive system before passing them to other parts of the body.
The liver also produces cholesterol, a waxy substance which aids digestion, builds cell membranes and produces vitamin D and steroid hormones.
Liver disease is a class of medical conditions characterized by reducing partly or completely the function of the liver, including liver failure.
Fibrosis is the formation of excess fibrous connective tissue in an organ or tissue in a reparative or reactive process associated with responding to injury.
In some cases, the forming of scaring also caused by overproduction of proinflammatory cytokines and/or interruption in the stage of injury recovery.
Liver fibrosis is a condition characterized by overly exuberant wound healing causing excessive connective tissue builds up in the liver. In other words, hepatic fibrosis is a condition in which a portion of the liver was affected by scars formation.
The exact causes of liver fibrosis are unknown. However, certain risk factors such as repeated liver injury caused by a virus infection, and a blockage in the bile ducts are found to elaborate on the onset of liver fibrosis.
Long-term untreated liver fibrosis can lead to cirrhosis, a condition of the severe scarring of the liver and life-threatening liver disease, including liver cancer.
The most common scale to grade the stage of liver fibrosis is the METAVIR scoring system. By examing the grade and stage of liver fibrosis of patients, their doctors can now determine the degree of severity to which patients' liver is affected.
Beta-Sitosterol is a phytochemical in the class of Phytosterols, belongings to the group of Lipids, found abundantly in avocados, rice bran, wheat germ, corn oils, fennel, peanuts, soybeans, hawthorn, basil, buckwheat. etc.
On finding a potential phytochemical for the prevention and treatment of liver diseases, researchers elucidated the β-sitosterol, a cholesterol-like phytosterol, which widely distributed in the plant kingdom. the anti-fibrotic effect on human hepatic stellate cell (HSC) model and dimethylnitrosamine (DMN)-induced mouse hepatic fibrosis model.
According to the results of the analysis of the hepato-fibrotic effect of β-sitosterol, at both of the mRNA and protein level,
* β-sitosterol inhibited the scar formation by down-regulating the mRNA and protein expression levels of collagen-1 and α-smooth muscle actin (α-SMA), a key biomarker for liver fibrosis and in activated HSC.
* Furthermore, oral administration of the β-sitosterol successfully alleviated the DMN-induced mouse liver damage and prevented collagen accumulation.
In other words, β-sitosterol exerted liver cell-protective effects against the liver damage and parameters associated with the onset of liver fibrosis.
Based on the findings, researchers said, " the effect of β-sitosterol on the TGF-β -or DMN-induced hepatofibrosis. Hence, we demonstrate the β-sitosterol as a potential therapeutic agent for the hepatofibrosis".
Taken altogether, beta-Sitosterol may be considered a supplement for the prevention and treatment of liver fibrosis, pending to the confirmation of the larger sample size and multicenter human study.
Intake of beta-Sitosterol in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Effects of β-sitosterol derived from Artemisia capillaris on the activated human hepatic stellate cells and dimethylnitrosamine-induced mouse liver fibrosis by Kim KS, Yang HJ, Lee JY, Na YC, Kwon SY, Kim YC, Lee JH1, Jang HJ. (PubMed)
Ovarian Cyst Miracle (tm)
Permanently and Naturally, Eliminate All Types of Ovarian Cysts Within 2 Months
Tuesday, April 7, 2020
Monday, April 6, 2020
Herbal Coltsfoot(Tussilago farfara) in the Modulation of Inflammatory Response
The immune system formed part of the body's defense plays a critical role in the protection of the body against infectious organisms.
The immune system executes the defense strategy through a series of the immune response by attacking foreign substances that invade body systems.
A variety of factors have been found to trigger immune responses include pathogens, damaged cells, and toxic compounds.
Inflammation is a natural response of the immune system which protects the body against the invasion of pathogens.
In the acute phase of tissue damage or wound, the immune white blood cells of the first line of defense stimulate the production of blood palette to cover the wound or damage and production of pro-inflammatory cytokines to the site of infection against microbial invasion.
Most cases of microbial invasion are stopped in the acute phase of infection, and the damaged tissue is slowly healing itself. However, in this phase, the overproduction of pro-inflammatory cytokines can lead to nearby cell death and the formation of scars.
If the immune system fails to destroy all microbial invasion in the acute phase of infection within a set period in 3 to weeks, it will compromise, leading to chronic low-grade inflammation.
The continued production of low levels of pro-inflammatory cytokines overtimes regardless of the causes can induce damage to organ tissues, and irreversible chronic diseases such as cardiovascular disease, diabetes, and cancer.
The Research Center for Molecular Medicine of the Austrian Academy of Sciences (Ce-M-M) wrote, "Humans have evolved highly complex immune systems that are composed of specialized immune cells that protect the host from infection and damage. But an uncontrolled immune response such as chronic inflammation can itself inflict damage".
And, "when the immune system is compromised by a genetic mutation, individuals become more susceptible to diseases such as autoimmune disease".
Coltsfoot(Tussilago farfara) is a perennial herbaceous plant, genus Tussilago, belonging to the family Asteraceae, native to Europe and Asia. The herb has been used over thousands of years to treat asthma, various coughs, bronchial congestion, respiratory disorders, headaches and obstruction in the nasal passage, etc.
On finding a potential compound for the treatment of asthma and bronchitis, researchers examined the coltsfoot inhibitory effects on lipopolysaccharide-induced inflammation in macrophages.
In a cecal ligation and puncture (CLP)-induced mouse model of sepsis, Tussilagone suppressed the parameters associated with the production of pro-inflammation such as nitric oxide and prostaglandin E2, and the inflammatory cytokines, tumor necrosis factor-alpha (TNF-α), particularly in lipopolysaccharide-stimulated RAW 264.7 cells and peritoneal macrophages.
In other words, Tussilago inhibits the production of inflammatory mediators and cytokines by suppressing the immune response associated with the first line of defense.
Additionally, the administration of Tussilagone at doses of 1 mg/kg and 10 mg/kg) protects the lung cells by decreasing the mortality and lung injury in CLP-activated septic mice.
Based on the findings, researchers said, " Tussilago exhibited protective effects against inflammation and polymicrobial sepsis by suppressing inflammatory mediators possibly via the inhibition of NF-κB activation and the MAP kinase pathway".
And, " These results suggest the possible use of Tussilago for developing novel therapeutic modalities for sepsis and other inflammatory diseases".
Taken altogether, coltsfoot may be considered a remedy for the treatment of inflammatory diseases associated with immune-inflammatory responses, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Tussilagone Inhibits the Inflammatory Response and Improves Survival in CLP-Induced Septic Mice by Kim YK1, Yeo MG2, Oh BK3, Kim HY4, Yang HJ5, Cho SS6, Gil M7, Lee KJ. (PubMed)
The immune system executes the defense strategy through a series of the immune response by attacking foreign substances that invade body systems.
A variety of factors have been found to trigger immune responses include pathogens, damaged cells, and toxic compounds.
Inflammation is a natural response of the immune system which protects the body against the invasion of pathogens.
In the acute phase of tissue damage or wound, the immune white blood cells of the first line of defense stimulate the production of blood palette to cover the wound or damage and production of pro-inflammatory cytokines to the site of infection against microbial invasion.
Most cases of microbial invasion are stopped in the acute phase of infection, and the damaged tissue is slowly healing itself. However, in this phase, the overproduction of pro-inflammatory cytokines can lead to nearby cell death and the formation of scars.
If the immune system fails to destroy all microbial invasion in the acute phase of infection within a set period in 3 to weeks, it will compromise, leading to chronic low-grade inflammation.
The continued production of low levels of pro-inflammatory cytokines overtimes regardless of the causes can induce damage to organ tissues, and irreversible chronic diseases such as cardiovascular disease, diabetes, and cancer.
The Research Center for Molecular Medicine of the Austrian Academy of Sciences (Ce-M-M) wrote, "Humans have evolved highly complex immune systems that are composed of specialized immune cells that protect the host from infection and damage. But an uncontrolled immune response such as chronic inflammation can itself inflict damage".
And, "when the immune system is compromised by a genetic mutation, individuals become more susceptible to diseases such as autoimmune disease".
Coltsfoot(Tussilago farfara) is a perennial herbaceous plant, genus Tussilago, belonging to the family Asteraceae, native to Europe and Asia. The herb has been used over thousands of years to treat asthma, various coughs, bronchial congestion, respiratory disorders, headaches and obstruction in the nasal passage, etc.
On finding a potential compound for the treatment of asthma and bronchitis, researchers examined the coltsfoot inhibitory effects on lipopolysaccharide-induced inflammation in macrophages.
In a cecal ligation and puncture (CLP)-induced mouse model of sepsis, Tussilagone suppressed the parameters associated with the production of pro-inflammation such as nitric oxide and prostaglandin E2, and the inflammatory cytokines, tumor necrosis factor-alpha (TNF-α), particularly in lipopolysaccharide-stimulated RAW 264.7 cells and peritoneal macrophages.
In other words, Tussilago inhibits the production of inflammatory mediators and cytokines by suppressing the immune response associated with the first line of defense.
Additionally, the administration of Tussilagone at doses of 1 mg/kg and 10 mg/kg) protects the lung cells by decreasing the mortality and lung injury in CLP-activated septic mice.
Based on the findings, researchers said, " Tussilago exhibited protective effects against inflammation and polymicrobial sepsis by suppressing inflammatory mediators possibly via the inhibition of NF-κB activation and the MAP kinase pathway".
And, " These results suggest the possible use of Tussilago for developing novel therapeutic modalities for sepsis and other inflammatory diseases".
Taken altogether, coltsfoot may be considered a remedy for the treatment of inflammatory diseases associated with immune-inflammatory responses, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Tussilagone Inhibits the Inflammatory Response and Improves Survival in CLP-Induced Septic Mice by Kim YK1, Yeo MG2, Oh BK3, Kim HY4, Yang HJ5, Cho SS6, Gil M7, Lee KJ. (PubMed)
Sunday, April 5, 2020
Omega 3 Fatty Acids Improve the Immune Functioning in Vivo
An immune system is a system of biological structures and processes within an organism that protects against disease by identifying and killing pathogens, including bacteria, viruses, parasites, etc. and tumor cells, including irregular cells growth, cancer cells to keep us healthy.
In most cases, the immune system does a great job of keeping people healthy and preventing infections. But sometimes problems with the immune system can lead to illness and infection.
Although the immune system has done a great job in protecting us against foreign invasion, unfortunately, during the process od their functions, they may induce the production of free radicals and chain of free radicals that can be harmful to our body.
Immunomodulatory activity is an action that improves the underactive immune function susceptible to the invasion of the foreign microorganism and inhibits the overactive immune system that causes autoimmune diseases.
In other words, depending on the substances that affect the immunomodulatory process, some may improve the immune function by modulating the genes involved immune responses and protect the immune system against toxins or immunotoxic effects such as abnormal allergic reactions, other such as heavy metals can induce opposite effects.
In normal immunity, active immunity may also be artificially acquired active immunity caused by the injection of the vaccine, a substance that contains antigen and passive immunity is an auto-response of the immune system against infection through the production of antigen.
Omega-3 fatty acids are phytochemicals in the class of lipids, found abundantly in deepsea fisk, dark-green leafy vegetables, grains, legumes, nuts, etc.
The three main components of Omega-3 fatty acids are alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).
On finding a potential phytochemical for the improvement of the immune functioning, researchers examined the long-chain n-3 PUFAs (LCPUFAs) anti-atopic disease risk in infants.
The study included pregnant Sprague-Dawley rats randomly assigned to consume either SDA (3 g SDA/100 g fat) or a control (no SDA) diet, 5 d before parturition and through lactation (21 d).
Additionally, for oral tolerance (OT) treatment, 10-d-old pups were fed ovalbumin (Ova; 200 μL of 8 mg/mL) or placebo daily for 5 d. At 21 d,
According to the experimental results of pups (both sexes) that were weaned to their respective maternal diet until 6 wk of age and killed, the SDA-enriched maternal diet showed higher levels of plasma phospholipid (PL) EPA (15 times higher), docosapentaenoic acid (DPA; 3 times higher), and DHA (1.3 times higher) content in 3-wk-old pups, accompanied by higher B-cell function [plasma ovalbumin-specific IgG1, compared with the control diet.
Furthermore, compared with pups fed a control diet, the splenocytes from pups fed with the SDA diet had more (23%) helper T (Th) cells (CD3+CD4+) and activated (12%) Th cells (CD4+CD28+) (P < 0.02) than controls.
Moreover, at 6 wk, the SDA group stimulated ex vivo with LPS, also had 30% more CD4+CD25+ splenocytes and produced less inflammatory IL-6 (50%) and TNF-α (30%) and more immunoregulatory IL-10 (45%) cytokines, compared to the control group.
However, the splenocytes and plasma PLs from the 6-wk-old SDA group had more EPA (2x) and DPA (3.5x) (P < 0.05), but not DHA, compared to the control group.
Additionally, the Ova-exposed group also had less (30%) plasma Ova-IgG1 than the placebo group.
Based on the findings, researchers said, "Feeding SDA during lactation and weaning altered immune responses in directions believed to be beneficial".
Taken altogether, Omega-3 fatty acids may be considered a functional food for the improvement of the immune response, pending to the confirmation of the larger sample size and multicenter human study.
Intake of Omega-3 fatty acids in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Feeding a Bioactive Oil Enriched in Stearidonic Acid during Early Life Influences Immune System Maturation in Neonatal Sprague-Dawley Rats by Patel D1, Goruk S1, Newell M1, Chen G1, Richard C1, Field CJ. (PubMed)
In most cases, the immune system does a great job of keeping people healthy and preventing infections. But sometimes problems with the immune system can lead to illness and infection.
Although the immune system has done a great job in protecting us against foreign invasion, unfortunately, during the process od their functions, they may induce the production of free radicals and chain of free radicals that can be harmful to our body.
Immunomodulatory activity is an action that improves the underactive immune function susceptible to the invasion of the foreign microorganism and inhibits the overactive immune system that causes autoimmune diseases.
In other words, depending on the substances that affect the immunomodulatory process, some may improve the immune function by modulating the genes involved immune responses and protect the immune system against toxins or immunotoxic effects such as abnormal allergic reactions, other such as heavy metals can induce opposite effects.
In normal immunity, active immunity may also be artificially acquired active immunity caused by the injection of the vaccine, a substance that contains antigen and passive immunity is an auto-response of the immune system against infection through the production of antigen.
Omega-3 fatty acids are phytochemicals in the class of lipids, found abundantly in deepsea fisk, dark-green leafy vegetables, grains, legumes, nuts, etc.
The three main components of Omega-3 fatty acids are alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).
On finding a potential phytochemical for the improvement of the immune functioning, researchers examined the long-chain n-3 PUFAs (LCPUFAs) anti-atopic disease risk in infants.
The study included pregnant Sprague-Dawley rats randomly assigned to consume either SDA (3 g SDA/100 g fat) or a control (no SDA) diet, 5 d before parturition and through lactation (21 d).
Additionally, for oral tolerance (OT) treatment, 10-d-old pups were fed ovalbumin (Ova; 200 μL of 8 mg/mL) or placebo daily for 5 d. At 21 d,
According to the experimental results of pups (both sexes) that were weaned to their respective maternal diet until 6 wk of age and killed, the SDA-enriched maternal diet showed higher levels of plasma phospholipid (PL) EPA (15 times higher), docosapentaenoic acid (DPA; 3 times higher), and DHA (1.3 times higher) content in 3-wk-old pups, accompanied by higher B-cell function [plasma ovalbumin-specific IgG1, compared with the control diet.
Furthermore, compared with pups fed a control diet, the splenocytes from pups fed with the SDA diet had more (23%) helper T (Th) cells (CD3+CD4+) and activated (12%) Th cells (CD4+CD28+) (P < 0.02) than controls.
Moreover, at 6 wk, the SDA group stimulated ex vivo with LPS, also had 30% more CD4+CD25+ splenocytes and produced less inflammatory IL-6 (50%) and TNF-α (30%) and more immunoregulatory IL-10 (45%) cytokines, compared to the control group.
However, the splenocytes and plasma PLs from the 6-wk-old SDA group had more EPA (2x) and DPA (3.5x) (P < 0.05), but not DHA, compared to the control group.
Additionally, the Ova-exposed group also had less (30%) plasma Ova-IgG1 than the placebo group.
Based on the findings, researchers said, "Feeding SDA during lactation and weaning altered immune responses in directions believed to be beneficial".
Taken altogether, Omega-3 fatty acids may be considered a functional food for the improvement of the immune response, pending to the confirmation of the larger sample size and multicenter human study.
Intake of Omega-3 fatty acids in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Feeding a Bioactive Oil Enriched in Stearidonic Acid during Early Life Influences Immune System Maturation in Neonatal Sprague-Dawley Rats by Patel D1, Goruk S1, Newell M1, Chen G1, Richard C1, Field CJ. (PubMed)
Saturday, April 4, 2020
Herbal Angelica Sinensis in the Prevention and Treatment of Cervical Spondylosis
Degenerative disease is a progression causes degenerative cell changes due to aging, affecting tissues or organs, which will increasingly deteriorate over time. ...
Normal bodily wear and tear or lifestyle choices (such as exercise or eating habits) may worsen degenerative diseases, but this depends on the disease.
Epidemiologically, most common degenerative diseases include
* Alzheimer's disease (AD).
*Amyotrophic lateral sclerosis (ALS, Lou Gehrig's disease).
* Cancers.
* Cystic fibrosis.
Cervical spondylosis is age-related wear and tear that affects the spinal disks in your neck.
In other words, these age-related wear and tear cause the disks to dehydrate and shrink, leading to osteoarthritis development, including bony projections along the edges of bones (bone spurs).
Cervical spondylosis is very common and worsens with age.
The most common symptoms of cervical spondylosis are, neck stiffness and pain and headache that may originate in the neck, pain in the shoulder or arms, inability to fully turn the head or bend the neck, sometimes interfering with driving and grinding noise or sensation when the neck is turned.
On finding a natural ingredient for the prevention and treatment of degenerative diseases, scientists examined the clinical effect of cervical paravertebral nerve block combined with Mailuoning and Angelica sinensis injection in the treatment of nerve-root type cervical spondylosis.
A total of 120 patients with nerve-root type cervical spondylosis who were randomly divided into a research group (n=60) that was treated by cervical paravertebral nerve block combined with Mailuoning and Angelica sinensis injection compared to the control group which was applied with glucocorticoid nerve block therapy.
According to the results of the comparison, the total therapeutic response rate of the research group was relatively higher than the control.
By comparing various clinical effect scores between the two groups, the research group also had advantages over the control group.
Furthermore, The treatment satisfaction degree of the research group was also higher than that of the control group.
Based on the findings, researchers concluded, " application of cervical paravertebral nerve block combined with Mailuoning and Angelica sinensis injection can achieve better medical results and achieve higher treatment satisfaction degree".
Taken altogether, angelica used together with other herbal medicines may be considered an adjunct remedy for the treatment of cervical spondylosis, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Clinical effect of cervical paravertebral nerve block combined with Mailuoning and Angelica sinensis in treatment of nerve-root type cervical spondylosis by Yu H1, Han J2, Liu X1, Zhang J1, Li Y. (PubMed)
Normal bodily wear and tear or lifestyle choices (such as exercise or eating habits) may worsen degenerative diseases, but this depends on the disease.
Epidemiologically, most common degenerative diseases include
* Alzheimer's disease (AD).
*Amyotrophic lateral sclerosis (ALS, Lou Gehrig's disease).
* Cancers.
* Cystic fibrosis.
Cervical spondylosis is age-related wear and tear that affects the spinal disks in your neck.
In other words, these age-related wear and tear cause the disks to dehydrate and shrink, leading to osteoarthritis development, including bony projections along the edges of bones (bone spurs).
Cervical spondylosis is very common and worsens with age.
The most common symptoms of cervical spondylosis are, neck stiffness and pain and headache that may originate in the neck, pain in the shoulder or arms, inability to fully turn the head or bend the neck, sometimes interfering with driving and grinding noise or sensation when the neck is turned.
On finding a natural ingredient for the prevention and treatment of degenerative diseases, scientists examined the clinical effect of cervical paravertebral nerve block combined with Mailuoning and Angelica sinensis injection in the treatment of nerve-root type cervical spondylosis.
A total of 120 patients with nerve-root type cervical spondylosis who were randomly divided into a research group (n=60) that was treated by cervical paravertebral nerve block combined with Mailuoning and Angelica sinensis injection compared to the control group which was applied with glucocorticoid nerve block therapy.
According to the results of the comparison, the total therapeutic response rate of the research group was relatively higher than the control.
By comparing various clinical effect scores between the two groups, the research group also had advantages over the control group.
Furthermore, The treatment satisfaction degree of the research group was also higher than that of the control group.
Based on the findings, researchers concluded, " application of cervical paravertebral nerve block combined with Mailuoning and Angelica sinensis injection can achieve better medical results and achieve higher treatment satisfaction degree".
Taken altogether, angelica used together with other herbal medicines may be considered an adjunct remedy for the treatment of cervical spondylosis, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Clinical effect of cervical paravertebral nerve block combined with Mailuoning and Angelica sinensis in treatment of nerve-root type cervical spondylosis by Yu H1, Han J2, Liu X1, Zhang J1, Li Y. (PubMed)
Friday, April 3, 2020
Plantbased Oleanolic Acid, The Promising Cancer Preventive Remedy
Cancer is the class of diseases associated with the growth of the cells disorderly and uncontrollably due to the alternation of DNA.
Most cases of cancer begin in the cells on the surface of the inner lining tissues of the organ or gland. At the early stage, most cancers are asymptomatic.
However, at the advanced stage, most cancers not can induce common symptoms such as gastrointestinal discomforts, unintended weight loss, loss of appetite and fatigue but also localized symptoms depending on the affected tissues and organs.
Cancers at this stage also can travel a distance away from the original site to induce secondary metastasis.
According to the statistics provided by the American cancer society, in 2018,1,735,350 new cases were diagnosed, representing more than 4,700 new cancer diagnoses each day.
The lifetime probability of being diagnosed with cancer is 39.7% for men and 37.6% for women.
Cancers are the second leading cause of death worldwide besides heart diseases.
Compared to all cancers, lung, breast, prostate, and colorectal cancers are the most common cancer in the US.
Angiogenesis is the process that develops new blood vessels from pre-existing vessels by invasive tumors to provide energy(nutrition and fluids) for cancerous cells growth and proliferation.
Oleanolic acid is a phytochemical in the subclass of Triterpenoid, belonging to the group of Terpenes found abundantly in honey mesquite, garlic, java apple, clove, etc.
On finding a potential plant for the treatment of chronic diseases, researchers examined the anti-cancer effect of Oleanolic acid (OA), a common pentacyclic triterpenoid.
According to the results of the analysis,
* Oleanolic acid exerted its effects as an inhibitor of the cellular inflammatory process, and the inducer of phase 2 xenobiotic biotransformation enzymes associated with cancer initiation.
* OA demonstrated its main anticancer effects mediated by caspases, 5' adenosine monophosphate-activated protein kinase in cellular energy homeostasis, extracellular signal-regulated kinase 1/2 in the regulation of cancer cell meiosis, mitosis, and postmitotic functions, matrix metalloproteinases in organogenesis, growth and normal tissue turnover, pro-apoptotic Bax.
* OA also promoted the overexpression of reactive oxygen species/apoptosis signal-regulating kinase 1/p38 mitogen-activated protein kinase, nuclear factor-κB, in the induction of cancer cytotoxicity.
Collectively, researchers said, " In this work, we critically review the scientific literature on the molecular targets of oleanolic acid implicated in the prevention and treatment of several types of cancer".
Taken altogether, potato may be considered a functional food for the prevention and treatment of cancer, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Oleanolic Acid Alters Multiple Cell Signaling Pathways: Implication in Cancer Prevention and Therapy by Žiberna L1, Šamec D2, Mocan A3,4, Nabavi SF5, Bishayee A6, Farooqi AA7, Sureda A8, Nabavi SM. (PubMed)
Most cases of cancer begin in the cells on the surface of the inner lining tissues of the organ or gland. At the early stage, most cancers are asymptomatic.
However, at the advanced stage, most cancers not can induce common symptoms such as gastrointestinal discomforts, unintended weight loss, loss of appetite and fatigue but also localized symptoms depending on the affected tissues and organs.
Cancers at this stage also can travel a distance away from the original site to induce secondary metastasis.
According to the statistics provided by the American cancer society, in 2018,1,735,350 new cases were diagnosed, representing more than 4,700 new cancer diagnoses each day.
The lifetime probability of being diagnosed with cancer is 39.7% for men and 37.6% for women.
Cancers are the second leading cause of death worldwide besides heart diseases.
Compared to all cancers, lung, breast, prostate, and colorectal cancers are the most common cancer in the US.
Angiogenesis is the process that develops new blood vessels from pre-existing vessels by invasive tumors to provide energy(nutrition and fluids) for cancerous cells growth and proliferation.
Oleanolic acid is a phytochemical in the subclass of Triterpenoid, belonging to the group of Terpenes found abundantly in honey mesquite, garlic, java apple, clove, etc.
On finding a potential plant for the treatment of chronic diseases, researchers examined the anti-cancer effect of Oleanolic acid (OA), a common pentacyclic triterpenoid.
According to the results of the analysis,
* Oleanolic acid exerted its effects as an inhibitor of the cellular inflammatory process, and the inducer of phase 2 xenobiotic biotransformation enzymes associated with cancer initiation.
* OA demonstrated its main anticancer effects mediated by caspases, 5' adenosine monophosphate-activated protein kinase in cellular energy homeostasis, extracellular signal-regulated kinase 1/2 in the regulation of cancer cell meiosis, mitosis, and postmitotic functions, matrix metalloproteinases in organogenesis, growth and normal tissue turnover, pro-apoptotic Bax.
* OA also promoted the overexpression of reactive oxygen species/apoptosis signal-regulating kinase 1/p38 mitogen-activated protein kinase, nuclear factor-κB, in the induction of cancer cytotoxicity.
Collectively, researchers said, " In this work, we critically review the scientific literature on the molecular targets of oleanolic acid implicated in the prevention and treatment of several types of cancer".
Taken altogether, potato may be considered a functional food for the prevention and treatment of cancer, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Oleanolic Acid Alters Multiple Cell Signaling Pathways: Implication in Cancer Prevention and Therapy by Žiberna L1, Šamec D2, Mocan A3,4, Nabavi SF5, Bishayee A6, Farooqi AA7, Sureda A8, Nabavi SM. (PubMed)
Thursday, April 2, 2020
Phytochemical Tocopherols Process Anti-Inflammatory Property
Anti-inflammatory activity is the use of a substance or treatment for the treatment of od inflammation or swelling.
Anti-inflammatory protein in the body displays anti-inflammatory properties against the risk of autoimmune diseases and immune pathologies such as rheumatoid arthritis, psoriasis or organ rejection.
Inflammation is a natural and systematic response of the immune system in the protection of the body against infection caused by the invasion of stimuli and pathogens.
After sensing the bodily injury or damage, the white blood cells of the immune first line of defense stimulates the production of a blood clot to seal the would quickly and proinflammatory cytokine to the site of infection with an aim to kill off all microorganisms which may cause harm to our body.
In this acute phase of the battle, most of the time is won by the immune system. However, overexpression of the pro-inflammatory cytokines can lead to the death of nearby healthy cells and improper skin healing with the formation of scars.
In some cases, certain proteins with duo anti and proinflammatory function also can switch to pro-inflammatory cytokines depending on the severity of the infection.
Chronic inflammation is a medical condition that lasts longer than 8 weeks, caused by the inability of the immune system to kill off all the microorganisms that have successfully entered the body during the acute phase of infection.
Some researchers suggested that the evolution of the immune system is to kill off the foreign micro invaders within the time frames of 8 weeks. If not, the immune system will adapt to the change, leading to chronic low-grade inflammation, a major cause of many chronic illnesses, including diabetes.
In some instances, chronic inflammation can also be caused by the immune system that mistakenly attacks the bodily tissue.
Tocopherols are phytochemicals of which many have vitamin E activity, belongings to the group of Lipids, found abundantly in butter, egg yolk, milk fat, some vegetable, and seed or nut oils, etc.
On finding a potential phytochemical for the treatment of diseases associated with inflammation, researchers examined the effects of γ-tocopherol (γT), δ-tocopherol, and γ-tocotrienol antioxidant and anti-inflammatory properties.
According to the tested analysis, γ-tocopherol (γT), δ-tocopherol, and γ-tocotrienol showed strong activity in scavenging reactive nitrogen species, inhibiting the enzymes associated with the mediation of the pro-inflammatory cytokines such as cyclooxygenase- and 5-lipoxygenase-catalyzed eicosanoids.
Furthermore, the phytochemicals also suppressed the proteins involving in proinflammatory signalings such as NF-κB and STAT3/6.
Moreover, the side-chain ω-oxidation involved in oxidative stress was also inhibited by the application.
In Vivo, long-chain carboxychromanols, especially 13'-carboxychromanols found in the phytochemicals exerted a strong anti-inflammatory activity in the study.
Based on the findings, researchers said, " In Vivo and Vitro, γT and tocotrienols may be useful against inflammation-associated diseases".
Taken altogether, tocopherols may be considered a supplement for the prevention and treatment of diseases associated with acute and chronic inflammation, pending to the confirmation of the larger sample size and multicenter human study.
Intake of tocopherols in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Natural forms of vitamin E: metabolism, antioxidant, and anti-inflammatoryactivities and their role in disease prevention and therapy by Jiang Q. (PubMed)
Anti-inflammatory protein in the body displays anti-inflammatory properties against the risk of autoimmune diseases and immune pathologies such as rheumatoid arthritis, psoriasis or organ rejection.
Inflammation is a natural and systematic response of the immune system in the protection of the body against infection caused by the invasion of stimuli and pathogens.
After sensing the bodily injury or damage, the white blood cells of the immune first line of defense stimulates the production of a blood clot to seal the would quickly and proinflammatory cytokine to the site of infection with an aim to kill off all microorganisms which may cause harm to our body.
In this acute phase of the battle, most of the time is won by the immune system. However, overexpression of the pro-inflammatory cytokines can lead to the death of nearby healthy cells and improper skin healing with the formation of scars.
In some cases, certain proteins with duo anti and proinflammatory function also can switch to pro-inflammatory cytokines depending on the severity of the infection.
Chronic inflammation is a medical condition that lasts longer than 8 weeks, caused by the inability of the immune system to kill off all the microorganisms that have successfully entered the body during the acute phase of infection.
Some researchers suggested that the evolution of the immune system is to kill off the foreign micro invaders within the time frames of 8 weeks. If not, the immune system will adapt to the change, leading to chronic low-grade inflammation, a major cause of many chronic illnesses, including diabetes.
In some instances, chronic inflammation can also be caused by the immune system that mistakenly attacks the bodily tissue.
Tocopherols are phytochemicals of which many have vitamin E activity, belongings to the group of Lipids, found abundantly in butter, egg yolk, milk fat, some vegetable, and seed or nut oils, etc.
On finding a potential phytochemical for the treatment of diseases associated with inflammation, researchers examined the effects of γ-tocopherol (γT), δ-tocopherol, and γ-tocotrienol antioxidant and anti-inflammatory properties.
According to the tested analysis, γ-tocopherol (γT), δ-tocopherol, and γ-tocotrienol showed strong activity in scavenging reactive nitrogen species, inhibiting the enzymes associated with the mediation of the pro-inflammatory cytokines such as cyclooxygenase- and 5-lipoxygenase-catalyzed eicosanoids.
Furthermore, the phytochemicals also suppressed the proteins involving in proinflammatory signalings such as NF-κB and STAT3/6.
Moreover, the side-chain ω-oxidation involved in oxidative stress was also inhibited by the application.
In Vivo, long-chain carboxychromanols, especially 13'-carboxychromanols found in the phytochemicals exerted a strong anti-inflammatory activity in the study.
Based on the findings, researchers said, " In Vivo and Vitro, γT and tocotrienols may be useful against inflammation-associated diseases".
Taken altogether, tocopherols may be considered a supplement for the prevention and treatment of diseases associated with acute and chronic inflammation, pending to the confirmation of the larger sample size and multicenter human study.
Intake of tocopherols in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Natural forms of vitamin E: metabolism, antioxidant, and anti-inflammatoryactivities and their role in disease prevention and therapy by Jiang Q. (PubMed)
Wednesday, April 1, 2020
Herbal Ashwagandha Inhibits the Onset of Atherosclerosis in Diabetics
Atherosclerosis is a medical condition caused by plaques accumulated on the wall of the arteries, leading to narrowing the arteries in transporting oxygenated blood to the heart and other parts of the body.
Depending on the blood obstruction, atherosclerosis can induce different types of heart disease and stroke.
Plaque is the make of cholesterols, calcium, and other toxic substances, including cadmium.
Hyperlipidemia is a medical condition characterized by abnormally high levels of cholesterol in the bloodstream.
Overexpression of cholesterol levels in the bloodstream has been linked to plaques accumulation on the arterial walls, a major cause of some forms of heart disease and stroke.
Untreated high blood cholesterol has been found to induce serious complications including carotid artery disease, coronary heart disease, peripheral artery disease, and stroke.
Dr, Yagi K, at the Institute of Applied Biochemistry in the analysis of the lipid peroxides and human diseases, said, "The lipid peroxidation (LPO) products are highly reactive and display marked biological effects, which, depending upon their concentration, cause selective alterations in cell signaling, protein and DNA damage, and cytotoxicity"
And. "Increased formation of lipid peroxides and aldehydes has been observed in atherosclerosis, ischemia-reperfusion, heart failure, Alzheimer’s disease, rheumatic arthritis, cancer, and other immunological disorders".
Cholesterol is the type of fat produced by the liver or from fat intake playing a critical role in the building of strong cell walls, production of vitamin D and steroid hormones and bile acid to aid digestion in the small intestine.
Cholesterol produced by the liver in a healthy individual is returned to the liver by high-density lipoprotein (HDL).
The healthy ratio of HDL/LDL cholesterol is any numbers that are less than 1/4.
Ashwagandha also is known as Withania somnifera is a nightshade plant in the genus of Withania, belonging to the family Solanaceae, native to the dry parts of India, North Africa, Middle East, and the Mediterranean.
The herbal medicine has been considered as Indian ginseng and used in Ayurvedic medicine over 3000 years to treat tumors and tubercular glands, carbuncles, memory loss, and ulcers and considered as anti-stress, cognition-facilitating, anti-inflammatory, and anti-aging herbal medicine.
On finding a potent compound for the prevention and treatment of atherosclerosis, researchers at the Meerut Institute of Engineering and Technology, Meerut, India, examined the anti hyperlipidemia and hyperglycemic of an aqueous extract of Withania coagulans (AWC).
According to the atherogenic index (AI) on streptozotocin (STZ)-induced diabetes.treated by AWC (1,000 mg/kg body weight, BW), AWC not reduced plasma glucose levels but also showed strong activity against levels of glucose in diabetic rats.
Furthermore, AWC at sub-chronic dosing also exerted significantly decreasing plasma levels of CHL, HDL, and TG only in STZ-induced diabetic rats.
Moreover, in STZ-induced diabetic animals compared to normal rats, repeated administration of AWC also significantly decreased AI and prevented weight loss.
Based on the findings, researchers said, "AWC showed anti-hyperlipidemic activity in diabetic rats and was suggested to be a suitable candidate for the treatment of atherosclerosis associated with diabetes".
Taken altogether, Ashwagandha may be considered a functional herb for the treatment of atherosclerosis in diabetics, pending to the result of larger sample size and multicenter study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Anti-hyperlipidemic activity of Withania coagulans in streptozotocin-induced diabetes: A potent anti-atherosclerotic agent by Saxena B. (PubMed)
Depending on the blood obstruction, atherosclerosis can induce different types of heart disease and stroke.
Plaque is the make of cholesterols, calcium, and other toxic substances, including cadmium.
Hyperlipidemia is a medical condition characterized by abnormally high levels of cholesterol in the bloodstream.
Overexpression of cholesterol levels in the bloodstream has been linked to plaques accumulation on the arterial walls, a major cause of some forms of heart disease and stroke.
Untreated high blood cholesterol has been found to induce serious complications including carotid artery disease, coronary heart disease, peripheral artery disease, and stroke.
Dr, Yagi K, at the Institute of Applied Biochemistry in the analysis of the lipid peroxides and human diseases, said, "The lipid peroxidation (LPO) products are highly reactive and display marked biological effects, which, depending upon their concentration, cause selective alterations in cell signaling, protein and DNA damage, and cytotoxicity"
And. "Increased formation of lipid peroxides and aldehydes has been observed in atherosclerosis, ischemia-reperfusion, heart failure, Alzheimer’s disease, rheumatic arthritis, cancer, and other immunological disorders".
Cholesterol is the type of fat produced by the liver or from fat intake playing a critical role in the building of strong cell walls, production of vitamin D and steroid hormones and bile acid to aid digestion in the small intestine.
Cholesterol produced by the liver in a healthy individual is returned to the liver by high-density lipoprotein (HDL).
The healthy ratio of HDL/LDL cholesterol is any numbers that are less than 1/4.
Ashwagandha also is known as Withania somnifera is a nightshade plant in the genus of Withania, belonging to the family Solanaceae, native to the dry parts of India, North Africa, Middle East, and the Mediterranean.
The herbal medicine has been considered as Indian ginseng and used in Ayurvedic medicine over 3000 years to treat tumors and tubercular glands, carbuncles, memory loss, and ulcers and considered as anti-stress, cognition-facilitating, anti-inflammatory, and anti-aging herbal medicine.
On finding a potent compound for the prevention and treatment of atherosclerosis, researchers at the Meerut Institute of Engineering and Technology, Meerut, India, examined the anti hyperlipidemia and hyperglycemic of an aqueous extract of Withania coagulans (AWC).
According to the atherogenic index (AI) on streptozotocin (STZ)-induced diabetes.treated by AWC (1,000 mg/kg body weight, BW), AWC not reduced plasma glucose levels but also showed strong activity against levels of glucose in diabetic rats.
Furthermore, AWC at sub-chronic dosing also exerted significantly decreasing plasma levels of CHL, HDL, and TG only in STZ-induced diabetic rats.
Moreover, in STZ-induced diabetic animals compared to normal rats, repeated administration of AWC also significantly decreased AI and prevented weight loss.
Based on the findings, researchers said, "AWC showed anti-hyperlipidemic activity in diabetic rats and was suggested to be a suitable candidate for the treatment of atherosclerosis associated with diabetes".
Taken altogether, Ashwagandha may be considered a functional herb for the treatment of atherosclerosis in diabetics, pending to the result of larger sample size and multicenter study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Anti-hyperlipidemic activity of Withania coagulans in streptozotocin-induced diabetes: A potent anti-atherosclerotic agent by Saxena B. (PubMed)
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