Socrates Said," Let foods be your medicine and let medicine be your foods". Let us all practice the values of the past wisdom to build a letter living and living health while we enjoy the delicious drinks

Thursday, April 27, 2017

All About #CurableVitamins: Vitamin K antagonists and children with heart diseases

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Vitamins are organic compounds and vital nutrients needed by your body to grow and develop in a profound way.
Vitamin K
Vitamin K(K1, phylloquinone; K2, menaquinones), is a fat soluble vitamin, found abundantly in leafy green vegetables, broccoli, and Brussels sprouts, etc. It is best known for promotion of coagulation and bone health.

In the study of "Vitamin K antagonists in children with heart diseases: height and VKORC1 genotype are the main determinants of the warfarin dose requirement" byMoreau C, Bajolle F, Siguret V, Lasne D, Golmard JL, Elie C, Beaune P, Cheurfi R, Bonnet D, Loriot MA., posted in US National Library of Medicine National Institutes of Health, found that height, target INR, VKORC1 and CYP2C9 genotypes were the main determinants of warfarin dose requirement, accounting for 48.1%, 4.4%, 18.2% and 2.0%, respectively, and explaining 69.7% of the variability. Our model predicted the warfarin dose within 7mg/week in 86.7% of patients. None of the covariates were associated with the time spent above or below the INR range. Whether this model predicts accurately the effective maintenance dose is currently investigated.


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