All About Minerals:Magnesium: Relationship between hypermagnesaemia in preterm labour and adverse health outcomes in babies

By Kyle J. Norton.


Magnesium is the eleventh most abundant element by mass in the human body. The adult body content is 25 g distributed in the skeleton and soft tissues. The chemical is essential in manipulating important biological polyphosphate such as ATP, DNA, and RNA and in functionming enzymes(a).

Magnesium: Relationship between hypermagnesaemia in preterm labour and adverse health outcomes in babies

In the study of the Magnesium and Neurologic Endpoints Trial (the so-called MagNET Trial) undertaken to establish whether the antenatal usage of magnesiumsulphate could protect neonates from having adverse neurologic outcomes, showed that unfortunately, the trial was suspended after 15 months of enrolment because of excess total paediatric mortality among those exposed to magnesiumsulphate. Following our original report and contrary to the original hypotheses, additional analyses of our data have actually shown a statistically significant increase in the risk of neonatal intraventricular hemorrhage, as well as total adverse paediatric outcomes, among those with higher levels of ionized magnesium at delivery. Nonetheless, it has been postulated, but not established, that anions of magnesium other than sulphate could have a more benign, or even beneficial, effect on health outcomes in the neonate(6).

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Sources
(6) http://www.ncbi.nlm.nih.gov/pubmed/12635881

Biography
Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.