All About Minerals: Chromium(chromium 3+): Chromium picolinate and chromium histidinate protects against renal dysfunction

By Kyle J. Norton.

Chromium(chromium 3+) is a essential mineral for the body in fat and carbohydrate metabolism, found abundantly in Beef, Eggs, Chicken, Oysters, Wheat germ, Green peppers, Banana, Apple, Etc.


Chromium(chromium 3+): Chromium picolinate and chromium histidinate protects against renal dysfunction


In the study to investigate the effects of chromium picolinate (CrPic) and chromiumhistidinate (CrHis) on nuclear factor-kappa B (NF-κB) and nuclear factor-E2-related factor-2 (Nrf2) pathway in the rat kidney by the Faculty of Veterinary Science, Firat University, the result show that in kidney tissue CrHis/CrPic increases Nrf2 level, parallelly decreases NF-κB and partially restores IκBα levels in HFD/STZ group, suggesting that CrPic and CrHis may play a role in antioxidant defense system via the Nrf2 pathway by reducing inflammation through NF-κβ p65 inhibition. Moreover, a greater reduction in NF-κB expression and greater increases in expressions of IκBα and Nrf2 in diabetic rats supplemented with CrHis than rats supplemented with CrPic suggest that CrHis has more favorable effects than CrPic(5).



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Sources
(5) http://www.ncbi.nlm.nih.gov/pubmed/22483164




Biography
Kyle J. Norton(Scholar, Master of Nutrition), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.