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Thursday, April 8, 2021

Herbal Devil's claw (Harpagophytum procumbens) May Induce Interaction with Drugs When Used for the Treatment of Neurological Disorders

Neurological disorders are medical conditions characterized by any disorder of the nervous system caused by structural, biochemical, or electrical abnormalities.

There are many forms of neurological disorders. The most common types of the disease include neurodegenerative disease, such as Alzheimer's disease (AD) and Parkinson's disease, epilepsy. multiple sclerosis and Migraines.

According to the Medical press, globally, the burden of neurological disorders (Alzheimer's disease, Parkinson's disease, stroke, epilepsy, etc) has increased substantially over the past 25 years.


These may be the results of over 25 years of economic expansion that have increased the living standard of billion of people in the Southeast Asian region.

The WHO in the evaluation of neurological disorders wrote, "Neurological disorders contribute to 92 million disability-adjusted life years (DALYs) in 2005 projected to increase to 103 million in 2030 (approximately a 12% increase). While Alzheimer's and other dementias are projected to show a 66% increase from 2005 to 2030".

Where one DALY represents the loss of the equivalent of one year of full health.

Believe it or not, there are more than 600 diseases of the central nervous system, including brain tumors, epilepsy, dementia such as Parkinson's disease and Alzheimer's disease, and stroke.


Alzheimer's disease (AD) is the most common neurodegenerative disease in the elderly in the Western world, associated with the worsening of memory, thinking and behavior that severe enough to affect language communication, memory, lifelong hobbies, or social life


On finding a natural ingredient for the prevention and treatment of neurodegenerative diseases, scientists examined the neuroprotective effects of Devil's claw.

Devil's claw also known as the wood spider, is a plant of genus Harpagophytum in the family of Pedaliaceae, native to South Africa.


The plant has been used as an herb in traditional and herbal medicine to treat fever, rheumatoid arthritis, skin, gallbladder, pancreas, stomach and kidney conditions, etc.

According to the active ingredients studied in the laboratory and clinical settings, Devil's claw showed promising natural therapeutics with anti-oxidative and anti-inflammatory salutations in protecting neuron integrity.

However, despite the promising and safe therapeutic benefits of CAM/herbal medicines, including Devil's claw, there exists a possible risk when combining them with prescription drugs.

In other words, Devil's claw may interact with drugs that have shown changes in blood pressure, hepatotoxicity, seizures, etc. when used in a combination.

Based on the results, researchers suggest, "Certainly, extensive work is needed to make sure that patients should take a regimen of protective and restorative therapy under an experienced healthcare professional".

Taken altogether, Devil's claw may be considered a remedy for the treatment of neurological disorders, pending the confirmation of the larger sample size and multicenter human study.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Natural or Plant Products for the Treatment of Neurological Disorders: Current Knowledge by Parvez MK. (PubMed)

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