Liver injury is some form of trauma that reduced liver function including acute toxicity such as an overdose of medicines, a blunt force, a penetrating foreign object such as a knife.
According to the statistic, liver injuries account for 5% of all traumas. In other words, liver injury is a common abdominal injury.
The liver is the largest internal organ in the human body, played an essential role in filtering blood from the intestine before passing them to other parts of the body.
The organ also produced cholesterol, a waxy substance that is needed to aid digestion and build strong cell membranes, production of steroid hormones and vitamins.
Most common symptoms associated with liver injury are shocks due to severe bleeding inducing a rapid heart rate, rapid breathing, and cold, clammy, pale, or bluish skin.
In some cases, blood accumulated in the abdomen may irritate the abdominal tissue, leading to symptoms of abdominal pain and swelling, and tenderness.
Depending on the size of the wound, most cases of liver injury are healed by itself. However, in severe cases, hospitalization may be necessary if the bleeding does not stop.
Out of many risk factors, an overdose of medicine has been found to be the number 1 factors involved in liver injury.
Dr.Stefan David, the lead scientist wrote, "Drug-induced liver injury (DILI) is common and nearly all classes of medications can cause liver disease. Most cases of DILI are benign, and improve after drug withdrawal".
However, "There are no definite risk factors for DILI, but pre-existing liver disease and genetic susceptibility may predispose certain individuals. Although most patients have clinical symptoms that are identical to other liver diseases, some patients may present with symptoms of systemic hypersensitivity. Treatment of drug and herbal-induced liver injury consists of rapid drug discontinuation and supportive care targeted to alleviate unwanted symptoms".
Betanin is phytochemicals in the class of red and yellow indole-derived pigments of Betacyanins, belongings to the group of Betalains, found abundantly in beets, chard, etc.
On finding a natural compound for the prevention of liver injury, researchers at the Shenyang University investigated the protective effect of betanin against liver injury induced by carbon tetrachloride (CCl4) in common carp (Cyprinus carpio L.).
The selected fish were intraperitoneally injected with 20 % (v/v in peanut oil) CCl4 at a volume of 0.5 mL/kg body weight at 20 days, after treatment with 1, 2, and 4 % betanin in fodder throughout the experiment.
Fish treated with CCl4 showed to induce liver CYP2E1 activity associated with reduced function of the liver, oxidative stress, and liver injury, observed by the depleted glycogen storage, increased serum liver damage, and stress markers such as aspartate aminotransferase (AST)/alanine aminotransferase (ALT) activities.
Compared to CCl4 treated fish, betanin not only reversed all parameters induced by the injection of CCl4 but also increased liver antioxidative capacity observed by the increased glutathione level and superoxide dismutase and catalase activities.
The 2 and 4 % of betanin groups demonstrated a better effect compared to the dose of 1%.
The results strongly suggested that betanin protected the liver against the injury induced by CCl4.
Collectively, researchers said, "the inhibition of CYP2E1 activity and oxidative stress may have significant roles in the protective effect of betanin".
Taken altogether, betanin may be considered supplements for the prevention and treatment of liver injury, pending the confirmation of a larger sample size and multicenter human study.
Intake of betanin in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Betanin attenuates carbon tetrachloride (CCl4)-induced liver injury in common carp (Cyprinus carpio L.) by Han J1, Gao C, Yang S, Wang J, Tan D. (PubMed)
(2) Drug-induced Liver Injury by Stefan David, MD1 and James P Hamilton, MD. (PMC)
Ovarian Cyst Miracle (tm)
Permanently and Naturally, Eliminate All Types of Ovarian Cysts Within 2 Months
Wednesday, June 30, 2021
Saturday, June 19, 2021
Kimchi (Fematneted Cabbage) Reduces the Risk of Colorectal Cancer
Colorectum formed part of the secretory system including the large intestine and the rectum is the second part of the digestive system involved in the absorption of water from the small bowel contents and breaks down of certain materials in the feces into substances of which some of them to be reabsorbed and reused by the body.
The colon-formed part of the large intestine plays a critical role in re-absorbing fluids and processing waste products from the body for elimination.
The colon consists of four parts: descending colon, ascending colon, transverse colon, and sigmoid colon
The rectum or the part of the large intestine nearest the rectum plays a temporary storehouse for feces.
Colorectal cancer is a medical condition caused by irregular cell growth in the tissue of the colon or rectum.
Most cases of colorectal cancer start in the cells on the surface of the inner lining in the colon and rectum, before penetrating into deeper layers to form a tumor through proliferation.
Colorectal cancer is relatively very common and slowly growing and progresses cancer in a predictable way.
The disease is more common in people over the age of 50. Regular colonoscopy after the age of 50 is valuable to detect the disease in the early stage, thereby increasing the rate of survival.
According to the statistics provided by the American Cancer Society, colorectal cancer, including cancer in the colon or rectum is the third most commonly diagnosed cancer and the second leading cause of cancer death in men and women combined in the United States.
In 2019, approximately 101,420 new cases of colon cancer and 44,180 new cases of rectal cancer will be diagnosed in the US.
The 5-year survival rate of colorectal cancer diagnosed at the localized stage is 90%. Sadly, only 39% of patients are diagnosed at this early stage.
Cabbage is a species of Brassica oleracea belongings to the family Brassicaceae (or Cruciferae), native to the Mediterranean region along the seacoast. The veggie has a short stem with a crowded mass of leaves, usually green but in some varieties, it may be red or purplish.
On findings of a natural wholefood for the prevention of cancer, researchers examined the effects of commercial kimchi (CK), standardized kimchi (SK), cancer-preventive kimchi (CPK), and anticancer kimchi (ACK), on colorectal carcinogenesis in mice.
Male BALB/c mice induced colon cancer with a single intraperitoneal injection of azoxymethane (AOM, 10 mg/kg body weight) and subsequent treatment with 2% dextran sulfate sodium (DSS) in drinking water for 7 days for two cycles.
According to the experimental analysis.
* Treatment with the methanolic extracts from different kimchis, particularly 1.89 g/kg of ACK, significantly increased colon length, decreased the ratio of colon weight/length, and resulted in the lowest number of tumors compared with the other kimchi-treated groups.
In other words, the kimchi extract protected the colonic cells against the alternation of DNA.
* Injection of ACK was able to suppress AOM- and DSS-induced colonic mucosal damage and neoplasia.
* ACK also significantly decreased the mRNA levels of proinflammatory cytokines (TNF-α, IL-6, and IFN-γ) as well as the mRNA and protein expression of inducible nitric oxide synthase and cyclooxygenase-2 (COX-2) to induce protein, lipid, and cell DNA damage.
* Mote importantly, kimchi extract enhanced the tumor-suppressive genes on AOM- and DSS-induced colorectal carcinogenesis in the BALB/c mice.
Based on the results, researchers wrote, " The anticancer effects of ACK were particularly potent. Thus, it is possible that the health-promoting sub-ingredients added to ACK might be used to prevent colon carcinogenesis in humans".
Taken altogether, cabbage may process anti colorectal activity, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Kimchi protects against azoxymethane/dextran sulfate sodium-induced colorectal carcinogenesis in mice by Kim HY1, Song JL, Chang HK, Kang SA, Park KY. (PubMed)
The colon-formed part of the large intestine plays a critical role in re-absorbing fluids and processing waste products from the body for elimination.
The colon consists of four parts: descending colon, ascending colon, transverse colon, and sigmoid colon
The rectum or the part of the large intestine nearest the rectum plays a temporary storehouse for feces.
Colorectal cancer is a medical condition caused by irregular cell growth in the tissue of the colon or rectum.
Most cases of colorectal cancer start in the cells on the surface of the inner lining in the colon and rectum, before penetrating into deeper layers to form a tumor through proliferation.
Colorectal cancer is relatively very common and slowly growing and progresses cancer in a predictable way.
The disease is more common in people over the age of 50. Regular colonoscopy after the age of 50 is valuable to detect the disease in the early stage, thereby increasing the rate of survival.
According to the statistics provided by the American Cancer Society, colorectal cancer, including cancer in the colon or rectum is the third most commonly diagnosed cancer and the second leading cause of cancer death in men and women combined in the United States.
In 2019, approximately 101,420 new cases of colon cancer and 44,180 new cases of rectal cancer will be diagnosed in the US.
The 5-year survival rate of colorectal cancer diagnosed at the localized stage is 90%. Sadly, only 39% of patients are diagnosed at this early stage.
Cabbage is a species of Brassica oleracea belongings to the family Brassicaceae (or Cruciferae), native to the Mediterranean region along the seacoast. The veggie has a short stem with a crowded mass of leaves, usually green but in some varieties, it may be red or purplish.
On findings of a natural wholefood for the prevention of cancer, researchers examined the effects of commercial kimchi (CK), standardized kimchi (SK), cancer-preventive kimchi (CPK), and anticancer kimchi (ACK), on colorectal carcinogenesis in mice.
Male BALB/c mice induced colon cancer with a single intraperitoneal injection of azoxymethane (AOM, 10 mg/kg body weight) and subsequent treatment with 2% dextran sulfate sodium (DSS) in drinking water for 7 days for two cycles.
According to the experimental analysis.
* Treatment with the methanolic extracts from different kimchis, particularly 1.89 g/kg of ACK, significantly increased colon length, decreased the ratio of colon weight/length, and resulted in the lowest number of tumors compared with the other kimchi-treated groups.
In other words, the kimchi extract protected the colonic cells against the alternation of DNA.
* Injection of ACK was able to suppress AOM- and DSS-induced colonic mucosal damage and neoplasia.
* ACK also significantly decreased the mRNA levels of proinflammatory cytokines (TNF-α, IL-6, and IFN-γ) as well as the mRNA and protein expression of inducible nitric oxide synthase and cyclooxygenase-2 (COX-2) to induce protein, lipid, and cell DNA damage.
* Mote importantly, kimchi extract enhanced the tumor-suppressive genes on AOM- and DSS-induced colorectal carcinogenesis in the BALB/c mice.
Based on the results, researchers wrote, " The anticancer effects of ACK were particularly potent. Thus, it is possible that the health-promoting sub-ingredients added to ACK might be used to prevent colon carcinogenesis in humans".
Taken altogether, cabbage may process anti colorectal activity, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Kimchi protects against azoxymethane/dextran sulfate sodium-induced colorectal carcinogenesis in mice by Kim HY1, Song JL, Chang HK, Kang SA, Park KY. (PubMed)
Wednesday, June 16, 2021
Phytochemical Betacyanins, the Best Free Radical Scavenger
Free radical scavengers are types of antioxidants that inhibit free radicals before they can induce a chain of reaction, leading to the onset of oxidative stress.
Antioxidants are stable atoms which inhibit oxidation caused by free radical.
Oxidative stress associated with chronic disease is caused by a long-term imbalanced ratio of free radicals and antioxidants. Oxidative stress has been found epidemiologically to induce proteins, lipid, and cellular damage, a major causes of heart disease, stroke, and diabetes.
Antioxidants besides produced by the body, they can also come into the body from dietary sources.
Normally, in a healthy individual, antioxidant enzymes produced by the liver are more than enough to counter the expression of free radicals induced by cell metabolism and the environment such as the air we breathe and the food we eat.
However, people with a weakened immune system, intake of antioxidant from outside sources such as fruits and vegetables can be helpful.
Not all free radicals are bad, in a moderate amount, free radicals are necessary for the body functioning, including the promotion of heart function in blood circulation.
Most common types of free radical scavengers produced by the human
* Catalases are antioxidants that protect the cell from oxidative damage by decomposed hydrogen peroxide to water and oxygen.
*Glutathione peroxidase, is a cytosolic enzyme produced by the host that dissolves hydrogen peroxide to water and oxygen and peroxide radicals to alcohols and oxygen.
*Superoxide dismutase (SOD) dissolves superoxide radicals into either ordinary molecular oxygen or hydrogen peroxide.
Most common types of free radical scavenger injected by the dietary sources
* Phenolics has been found to inactivate certain free radicals such as tocopherol found in tea, soybean, corn, grape, and safflower,
* Ascorbate or vitamin C is found most abundantly in green vegetables, citrus fruits, tomatoes, berries, and potatoes.
* Thiols that processed the function to quench singlet oxygen is found in onion, garlic, beer, cabbage, tea, and coffee
* Carotenoids that process the function in the deactivation of free radical with singlet oxygen, are found in tomato and carrot
Betacyanins are phytochemicals in the class of red and yellow indole-derived pigments, belonging to the group of Betalains, found abundantly in beets, chard, etc.
On finding a natural pigment which processes a significant antioxidant activity, researchers examined the Betacyanins effects on peroxyl radicals.
Based on the results of the tested assays, researchers found that* Betanin found in betacyanins was a weak retarder in methanol and an effective chain-breaking antioxidant in the liposomal model
* Compared to betanin, betanidin other compound found betacyanins, behaved as a chain-terminating antioxidant in both models.
Furthermore, according to the kinetic parameters characterizing peroxyl radical-scavenging activity, betanidin was more effective than betanin.
The results suggested that the antioxidant efficacy found in betacyanins was associated with all phytochemicals, including the major compound betanin and betanidin that work synergistically to exhibit anti-free radicals activity.
Moreover, in the assessment of the antioxidant capacity of the betacyanins in an index of radical scavenging ability, using the peroxyl radical generating system in the presence of AAPH and NO-generating system using NOR3 as a NO donor suggested that
* Betacyanins expressed peroxyl radical scavenging capacity in a dose-dependent in the low concentration range (25-100 nM).
* In free radical NO, administration of betacyanins also reduced the nitrite level in the low concentration range of 2.5-20 μM.
* The antioxidant capacity according to individual major compounds of betanidin, betanin, and phyllocactin, are 10.70, 3.31 and 2.83 mol-TEA/mol respectively.
* The IC₅₀ values (μM) of nitrogen radical scavenging activity of betanin, phyllocactin and betanidin are 24.48, 17.51, and 6.81, respectively.
Dr. Taira J, the lead scientist based on the findings wrote, "These results indicated that betacyanins have a strong antioxidant capacity, particularly betanidin with a catechol group had higher activity than those of the glycoside of betacyanins".
Taken altogether, betacyanins processed abundantly bioactive ingredient betanin may be considered a remedy for the prevention and treatment of liver steatosis, pending to the confirmation of the larger sample size and multicenter human study.
Intake of betacyanins in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Betacyanins as phenol antioxidants. Chemistry and mechanistic aspects of the lipoperoxyl radical-scavenging activity in solution and liposomes by Tesoriere L1, Allegra M, Gentile C, Livrea MA.(PubMed)
(2) Antioxidant capacity of betacyanins as radical scavengers for peroxyl radical and nitric oxide by Taira J1, Tsuchida E2, Katoh MC2, Uehara M2, Ogi T. (PubMed)
Antioxidants are stable atoms which inhibit oxidation caused by free radical.
Oxidative stress associated with chronic disease is caused by a long-term imbalanced ratio of free radicals and antioxidants. Oxidative stress has been found epidemiologically to induce proteins, lipid, and cellular damage, a major causes of heart disease, stroke, and diabetes.
Antioxidants besides produced by the body, they can also come into the body from dietary sources.
Normally, in a healthy individual, antioxidant enzymes produced by the liver are more than enough to counter the expression of free radicals induced by cell metabolism and the environment such as the air we breathe and the food we eat.
However, people with a weakened immune system, intake of antioxidant from outside sources such as fruits and vegetables can be helpful.
Not all free radicals are bad, in a moderate amount, free radicals are necessary for the body functioning, including the promotion of heart function in blood circulation.
Most common types of free radical scavengers produced by the human
* Catalases are antioxidants that protect the cell from oxidative damage by decomposed hydrogen peroxide to water and oxygen.
*Glutathione peroxidase, is a cytosolic enzyme produced by the host that dissolves hydrogen peroxide to water and oxygen and peroxide radicals to alcohols and oxygen.
*Superoxide dismutase (SOD) dissolves superoxide radicals into either ordinary molecular oxygen or hydrogen peroxide.
Most common types of free radical scavenger injected by the dietary sources
* Phenolics has been found to inactivate certain free radicals such as tocopherol found in tea, soybean, corn, grape, and safflower,
* Ascorbate or vitamin C is found most abundantly in green vegetables, citrus fruits, tomatoes, berries, and potatoes.
* Thiols that processed the function to quench singlet oxygen is found in onion, garlic, beer, cabbage, tea, and coffee
* Carotenoids that process the function in the deactivation of free radical with singlet oxygen, are found in tomato and carrot
Betacyanins are phytochemicals in the class of red and yellow indole-derived pigments, belonging to the group of Betalains, found abundantly in beets, chard, etc.
On finding a natural pigment which processes a significant antioxidant activity, researchers examined the Betacyanins effects on peroxyl radicals.
Based on the results of the tested assays, researchers found that* Betanin found in betacyanins was a weak retarder in methanol and an effective chain-breaking antioxidant in the liposomal model
* Compared to betanin, betanidin other compound found betacyanins, behaved as a chain-terminating antioxidant in both models.
Furthermore, according to the kinetic parameters characterizing peroxyl radical-scavenging activity, betanidin was more effective than betanin.
The results suggested that the antioxidant efficacy found in betacyanins was associated with all phytochemicals, including the major compound betanin and betanidin that work synergistically to exhibit anti-free radicals activity.
Moreover, in the assessment of the antioxidant capacity of the betacyanins in an index of radical scavenging ability, using the peroxyl radical generating system in the presence of AAPH and NO-generating system using NOR3 as a NO donor suggested that
* Betacyanins expressed peroxyl radical scavenging capacity in a dose-dependent in the low concentration range (25-100 nM).
* In free radical NO, administration of betacyanins also reduced the nitrite level in the low concentration range of 2.5-20 μM.
* The antioxidant capacity according to individual major compounds of betanidin, betanin, and phyllocactin, are 10.70, 3.31 and 2.83 mol-TEA/mol respectively.
* The IC₅₀ values (μM) of nitrogen radical scavenging activity of betanin, phyllocactin and betanidin are 24.48, 17.51, and 6.81, respectively.
Dr. Taira J, the lead scientist based on the findings wrote, "These results indicated that betacyanins have a strong antioxidant capacity, particularly betanidin with a catechol group had higher activity than those of the glycoside of betacyanins".
Taken altogether, betacyanins processed abundantly bioactive ingredient betanin may be considered a remedy for the prevention and treatment of liver steatosis, pending to the confirmation of the larger sample size and multicenter human study.
Intake of betacyanins in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Betacyanins as phenol antioxidants. Chemistry and mechanistic aspects of the lipoperoxyl radical-scavenging activity in solution and liposomes by Tesoriere L1, Allegra M, Gentile C, Livrea MA.(PubMed)
(2) Antioxidant capacity of betacyanins as radical scavengers for peroxyl radical and nitric oxide by Taira J1, Tsuchida E2, Katoh MC2, Uehara M2, Ogi T. (PubMed)
Wednesday, June 9, 2021
Phytochemical Tocopherols Kill Acute Myeloid Leukemia Cells in Vitro
Leukemia is a condition characterized by an abnormal increase of white blood cells produced by the bone marrow and/or the lymphatic system. Depending on the malignant granulocytes or lymphocytes, leukemia is classified into myelogenous or lymphoblastic leukemia.
Bone marrow is the soft tissue inside the hollow center of the major bone. including spine, pelvis, underarm, leg. etc.
Acute leukemia is a condition caused by a rapid increase in the numbers of extremely immature white blood cells that appear in the bloodstream in the other parts of the body, including tissue and organs.
Acute leukemia can also be classified into
* Acute lymphoblastic leukemia (ALL)
Acute lymphocytic leukemia (ALL) is a type of cancer with the abnormal growth of extremely immature lymphocytes overproduced by the bone marrow and/or lymphatic system. The condition has a tendency to multiply quickly, leading to the death of normal white blood cells in the bone marrow and/or lymphatic system.
In ALL, lymphocytes appear immature in the bloodstream. Acute lymphoblastic leukemia (ALL) is the most common children forms of leukemia with about 80% of all cases.
* Acute myeloid leukemia (AML)
Acute myelogenous leukemia (AML) is a cancer of the myelogenous lining caused by the rapid growth of abnormal granulocytes accumulated in the bone marrow, interfering with the normal blood cells. In AML, granulocytes appear immature in the bloodstream.
According to the statistics, in 2019, approximately 21,450 people of all ages including 11,650 men and boys and 9,800 women and girls) in the United States will be diagnosed with AML.
AML is the second most common type of leukemia diagnosed in adults and children, but most cases occur in adults. AML makes up 32% of all adult leukemia cases.
The 5-year survival rate for people 20 and older with AML is approximately 24%. For people younger than 20, the survival rate is 67%.
Tocopherols are phytochemicals of which many have vitamin E activity, belonging to the group of Lipids, found abundantly in butter, egg yolk, milk fat, some vegetable, and seed or nut oils, etc.
On finding a potential phytochemical for the treatment of leukemia, researchers examined the effect of δ-tocopherol in acute myeloid leukemia.
Compared to other leukemia cell lines, δ-T as low as 20 µM showed a strong activity on AML cell line KG-1.
The δ-T inhibition of AML cell line KG-1 was observed in a set of primary cells collected from patients newly diagnosed with AML.
Furthermore, δ-T also induced apoptosis and cell cycle arrest against KG-1 cells.
The results of δ-T anti-AML activity were attributed to the inhibition of protein cyclin-d1 associated with the G1 phase of the cell cycle arrest and a set of homeobox proteins associated with cancer cell growth and apoptosis.
Taken altogether, tocopherols may be considered a supplement for the prevention and treatment of acute myeloid leukemia pending the confirmation of the larger sample size and multicenter human study.
Intake of tocopherols in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Reduction in Cell Viability and in Homeobox Protein Levels Following in Vitro Exposure to δ-tocopherol in Acute Myeloid Leukemia by Collins J1, Safah H2, Lobelle-Rich P2, Whaley S3, Campbell S3, Saba NS. (PubMed)
Bone marrow is the soft tissue inside the hollow center of the major bone. including spine, pelvis, underarm, leg. etc.
Acute leukemia is a condition caused by a rapid increase in the numbers of extremely immature white blood cells that appear in the bloodstream in the other parts of the body, including tissue and organs.
Acute leukemia can also be classified into
* Acute lymphoblastic leukemia (ALL)
Acute lymphocytic leukemia (ALL) is a type of cancer with the abnormal growth of extremely immature lymphocytes overproduced by the bone marrow and/or lymphatic system. The condition has a tendency to multiply quickly, leading to the death of normal white blood cells in the bone marrow and/or lymphatic system.
In ALL, lymphocytes appear immature in the bloodstream. Acute lymphoblastic leukemia (ALL) is the most common children forms of leukemia with about 80% of all cases.
* Acute myeloid leukemia (AML)
Acute myelogenous leukemia (AML) is a cancer of the myelogenous lining caused by the rapid growth of abnormal granulocytes accumulated in the bone marrow, interfering with the normal blood cells. In AML, granulocytes appear immature in the bloodstream.
According to the statistics, in 2019, approximately 21,450 people of all ages including 11,650 men and boys and 9,800 women and girls) in the United States will be diagnosed with AML.
AML is the second most common type of leukemia diagnosed in adults and children, but most cases occur in adults. AML makes up 32% of all adult leukemia cases.
The 5-year survival rate for people 20 and older with AML is approximately 24%. For people younger than 20, the survival rate is 67%.
Tocopherols are phytochemicals of which many have vitamin E activity, belonging to the group of Lipids, found abundantly in butter, egg yolk, milk fat, some vegetable, and seed or nut oils, etc.
On finding a potential phytochemical for the treatment of leukemia, researchers examined the effect of δ-tocopherol in acute myeloid leukemia.
Compared to other leukemia cell lines, δ-T as low as 20 µM showed a strong activity on AML cell line KG-1.
The δ-T inhibition of AML cell line KG-1 was observed in a set of primary cells collected from patients newly diagnosed with AML.
Furthermore, δ-T also induced apoptosis and cell cycle arrest against KG-1 cells.
The results of δ-T anti-AML activity were attributed to the inhibition of protein cyclin-d1 associated with the G1 phase of the cell cycle arrest and a set of homeobox proteins associated with cancer cell growth and apoptosis.
Taken altogether, tocopherols may be considered a supplement for the prevention and treatment of acute myeloid leukemia pending the confirmation of the larger sample size and multicenter human study.
Intake of tocopherols in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Reduction in Cell Viability and in Homeobox Protein Levels Following in Vitro Exposure to δ-tocopherol in Acute Myeloid Leukemia by Collins J1, Safah H2, Lobelle-Rich P2, Whaley S3, Campbell S3, Saba NS. (PubMed)
Thursday, June 3, 2021
Broccoli Processes Anti Nasopharyngeal Cancer Activity
Cancers are a class of chronic and medical conditions characterized by cells growth irregularly and disorderly in the tissue of a specific organ.
Most cases of cancer start in the cell on the surface of the inner lining of organ tissue caused by the alternation of the cell DNA.
According to the National Cancer Institute, approximately 38.4% of men and women will be diagnosed with cancer at some point during their lifetimes, based on the 2013–2015 data.
In 2017, about15,270 children and adolescents ages 0 to 19 were diagnosed with cancer. Cancer in the same year also causes the death 1,790 of children and adolescents Americans.
The nasopharynx is the upper part of the pharynx, connecting with the nasal cavity above the soft palate that allows a person to breathe through the nose.
Nasopharyngeal cancer is a medical condition characterized by cells growing irregularly and disorderly in the tissues of the nasopharynx.
Most cases of nasopharyngeal cancer start in the cells on the surface of the inner lining of the nasopharynx.
According to the statistics provided by the American cancer society, nasopharyngeal cancer (NPC) is quite rare in the United States). The risk of cancer is less than one case for every 100,000 people.
Epidemiologically, some patients at this stage may also experience symptoms of frequent ear infections, hearing loss, and headaches.
The exact causes of nasopharyngeal cancer are unknown. Gender, family history, ethnicity, where you live, poor diet, infected by the Epstein-Barr virus are some of the prevalent factors of nasopharyngeal cancer.
On finding a potential plant that processes anti-cancer activity researchers compared the effects investigate the role of miRNAs from broccoli in human nasopharyngeal cancer (NPC).
Where microRNAs (miRNAs), a small non-coding RNA molecule found in plants, animals, and some viruses have been documented as having an important role in the development of cancer.
According to the analysis of a total of 84 conserved miRNAs and 184 putative novel miRNAs in broccoli by sequencing technology, the most abundant miR156a mimic inhibited the EMT of NPC cells in vitro.
The molecular genetics 3' UTR of Junctional adhesion molecule A (JAMA) associated with cancer cell migration and tight junctions was inhibited by the miR156a mimic on the tested EMT of NPC.
Collectively, researchers said, "These miRNA profiles of broccoli provide a fundamental basis for further research. Moreover, the discovery of miR156a may have clinical implications for the treatment of patients with NPC".
Taken altogether, broccoli which consists of microRNAs may be considered a functional food for the prevention and treatment of atherothrombotic diseases, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) miR156a Mimic Represses the Epithelial-Mesenchymal Transition of Human Nasopharyngeal Cancer Cells by Targeting Junctional Adhesion Molecule A by Tian Y1, Cai L1, Tian Y2, Tu Y1, Qiu H1, Xie G1, Huang D1, Zheng R1, Zhang W. (PubMed)
Most cases of cancer start in the cell on the surface of the inner lining of organ tissue caused by the alternation of the cell DNA.
According to the National Cancer Institute, approximately 38.4% of men and women will be diagnosed with cancer at some point during their lifetimes, based on the 2013–2015 data.
In 2017, about15,270 children and adolescents ages 0 to 19 were diagnosed with cancer. Cancer in the same year also causes the death 1,790 of children and adolescents Americans.
The nasopharynx is the upper part of the pharynx, connecting with the nasal cavity above the soft palate that allows a person to breathe through the nose.
Nasopharyngeal cancer is a medical condition characterized by cells growing irregularly and disorderly in the tissues of the nasopharynx.
Most cases of nasopharyngeal cancer start in the cells on the surface of the inner lining of the nasopharynx.
According to the statistics provided by the American cancer society, nasopharyngeal cancer (NPC) is quite rare in the United States). The risk of cancer is less than one case for every 100,000 people.
Epidemiologically, some patients at this stage may also experience symptoms of frequent ear infections, hearing loss, and headaches.
The exact causes of nasopharyngeal cancer are unknown. Gender, family history, ethnicity, where you live, poor diet, infected by the Epstein-Barr virus are some of the prevalent factors of nasopharyngeal cancer.
On finding a potential plant that processes anti-cancer activity researchers compared the effects investigate the role of miRNAs from broccoli in human nasopharyngeal cancer (NPC).
Where microRNAs (miRNAs), a small non-coding RNA molecule found in plants, animals, and some viruses have been documented as having an important role in the development of cancer.
According to the analysis of a total of 84 conserved miRNAs and 184 putative novel miRNAs in broccoli by sequencing technology, the most abundant miR156a mimic inhibited the EMT of NPC cells in vitro.
The molecular genetics 3' UTR of Junctional adhesion molecule A (JAMA) associated with cancer cell migration and tight junctions was inhibited by the miR156a mimic on the tested EMT of NPC.
Collectively, researchers said, "These miRNA profiles of broccoli provide a fundamental basis for further research. Moreover, the discovery of miR156a may have clinical implications for the treatment of patients with NPC".
Taken altogether, broccoli which consists of microRNAs may be considered a functional food for the prevention and treatment of atherothrombotic diseases, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) miR156a Mimic Represses the Epithelial-Mesenchymal Transition of Human Nasopharyngeal Cancer Cells by Targeting Junctional Adhesion Molecule A by Tian Y1, Cai L1, Tian Y2, Tu Y1, Qiu H1, Xie G1, Huang D1, Zheng R1, Zhang W. (PubMed)
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