#Antioxidant Beta-Sitosterol Exhibits a Protective Effect on Alzheimer's, Scientists Suggest

Neurological diseases are the medical conditions of brain disorders. Anything that involves structural, biochemical, or electrical abnormalities in the brain, spinal cord, or other nerves, including brain damage is considered neuro disease.

The most common neurodegenerative diseases in the elderly are dementia. Depending on the brain regions that are damaged or dysfunctional, dementia can be Parkinson's, Alzheimer's,... or Huntington's disease.

Genetic mutation inherited from parents such as the NOTCH3 gene is the most common autosomal dominant cause of stroke and vascular dementia.

Neurodegenerative diseases are a class of conditions associated with the progressive loss of neurons in the brain caused by several mechanisms, including toxicity and oxygen deficiency.

Dementia is a cluster of conditions including Parkinson’s, Alzheimer’s, and Huntington’s disease, leading to a negative influence on the body's functioning, including balance, movement, talking, breathing, and heart function.

There is no single cause of the progressive death of brain neurons. Epidemiologically, genetic preposition and medical conditions, such as alcoholism, brain cancer or a stroke in the brain are some of the most common prevalent factors found in patients with neurological diseases.


The most common form of neurodegenerative disease in North America is Alzheimer's disease (AD).

Alzheimer's disease is a brain disorder correlated with major reductions of neurons to the respective target areas through the destruction of brain cells, causing cognitive modalities severe enough to affect language communication, memory, lifelong hobbies, or social life. Alzheimer's gets worse over time, and it is fatal.

According to statistics, over 25 million people in the world today are affected by dementia and most are suffering from Alzheimer's disease.


Beta-Sitosterol is a phytochemical in the class of Phytosterols, belongings to the group of Lipids, found abundantly in avocados, rice bran, wheat germ, corn oils, fennel, peanuts, soybeans, hawthorn, basil, and buckwheat. etc.

On finding a potential phytochemical for the prevention and treatment of neurodegenerative diseases, researchers elucidated the effects of sterol β-Sitosterol on the production of platelet Aβ in Alzheimer's disease (AD).

According to the results in learning and memory in amyloid protein precursor/presenilin 1 (APP/PS1) double transgenic mice which were treated with β-Sitosterol for four weeks, * β-Sitosterol treatment improved spatial learning and recognition memory ability, and reduced plaque load in APP/PS1 mice.

* β-Sitosterol treatment reversed dendritic spine loss in APP/PS1 mice and reversed the decreased hippocampal neuron miniature excitatory postsynaptic current frequency.

In other words, β-Sitosterol demonstrated a neuroprotective effect that may offer a novel pharmaceutical agent for the treatment of AD.

Based on the findings, researchers said, " these findings suggest that β-Sitosterol ameliorates memory and learning impairment in APP/PS1 mice and possibly decreases Aβ deposition".

Beta-Sitosterol may be considered a remedy for the prevention and treatment of AD, pending the confirmation of the larger sample size and multicenter human study.

Intake of beta-Sitosterol in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) β-Sitosterol treatment attenuates cognitive deficits and prevents amyloid plaque deposition in amyloid protein precursor/presenilin 1 mice by Ye JY1, Li L1, Hao QM1, Qin Y1, Ma CS. (PubMed)

#Antioxidant Beta-Sitosterol Reduces the Risk and Onset of Tuberculosis

The lung is a vital organ of the human being, located near the backbone on either side of the heart with functions of inhaling oxygen from the air then transporting them to the bloodstream to nourish the body cells' needs and exhaling carbon dioxide from the bloodstream.



Chronic respiratory diseases are medical conditions related to abnormal function of the airways and other parts of the lung.

Tuberculosis (TB) is a disease caused by Mycobacterium tuberculosis. Commonly, the bacterium attacked the lung tissue but in some cases, it also can cause major damage to other parts of the body.

The disease is very contagious, as types of bacteria that cause TB can spread from person to person through microscopic droplets released into the air.

In other words, people can be infected by TB if they can to close contact with TB patients through tuberculosis coughs, speaks, sneezes, spits,.... and laughs.

The disease is rare in the Western world, however, according to the report of WHO of the region including 36 countries in the Western Pacific Region, approximately 1.4 million notified cases of all forms of TB in 2011 (75 per 100 000 population), corresponding to 23% of the total cases notified globally.

There were 0.6 million new smear-positive cases notified in 2011 (32 per 100 000 population), corresponding to 22% of the total smear-positive cases notified globally.


The most common TB complications has been recorded are spinal pain, back pain, and stiffness, joint damage.


Furthermore, depending on the diseases associated with the complication induced by tuberculous, patients may also experience hip and knee malformation, swelling of the membranes that cover the brain, liver or kidney problems, and heart disorders.


Beta-Sitosterol is a phytochemical in the class of Phytosterols, belongings to the group of Lipids, found abundantly in avocados, rice bran, wheat germ, corn oils, fennel, peanuts, soybeans, hawthorn, basil, and buckwheat. etc.

On finding a potential phytochemical for the prevention and treatment of infectious diseases, researchers examined the adjuvant effect of beta-sitosterol and its glucoside in the treatment of culture-proven pulmonary tuberculosis (PTB).

The blinded randomized placebo-controlled trial was conducted by using the culture-proven drug-sensitive PTBs from patients hospitalized for the duration of treatment.

According to the chemical analysis,
* Weight gain was significantly greater in the sitosterol group (mean weight gain 8.9 kg) compared to the placebo.

* However, the speed of achieving culture negativity, radiological improvement, and induration on Mantoux testing was similar in the two groups.

* Most importantly, the sitosterol treatment group demonstrated a significant increase in lymphocyte counts and eosinophil counts from baseline compared to the placebo.

Collectively, scientists suggested, "The study has shown significantly improved weight gain and higher lymphocyte and eosinophil counts in PTB patients receiving sitosterols in addition to an efficacious antituberculosis regimen".

Taken altogether, beta-Sitosterol may be considered a supplement for the prevention and treatment of tuberculosis, pending the confirmation of the larger sample size and multicenter human study.

Intake of beta-Sitosterol in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals' Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) A randomised placebo-controlled trial of the efficacy of beta-sitosterol and its glucoside as adjuvants in the treatment of pulmonary tuberculosis by Donald PR1, Lamprecht JH, Freestone M, Albrecht CF, Bouic PJ, Kotze D, van Jaarsveld PP. (PubMed)