Herbal Enchinanea, A Promising Antioxidant and Anti-inflammatory Agent

Infection is a condition caused by a harmful microbial invasion of the body tissues

Most cases of bacterial infection are treated with antibiotics. However, bacterias are very adaptable, overuse of antibiotics has been found to make them resistant to antibiotics.

Out of trillions of strains of bacteria in the world, only a few cause diseases in humans. Believe it or not, our gut contains trillion microorganisms, most of them are bacteria.

The most common symptoms of bacterial infection are redness and heat, swelling, fever, pain at the site of infection.

In severe cases, the patient may also experience symptoms of swollen lymph glands.

Most cases of bacterial infection are treated successfully if the types of bacteria that cause the infection are identified.

Antioxidants are stable atom that plays a critical role in protecting the body against the attack of free radicals.

In other words, antioxidants inhibited the onset of free radical before they can cause a chain reaction in facilitating the protein, lipid, and cell damage.

Antioxidants can either produced by the liver or intake from dietary sources. Under normal conditions, antioxidant enzymes produced by the body in a healthy individual are good enough to counter the bombardment of free radical attacks.

However, in people with a weakened immune system, the intake of dietary sources of antioxidants may be necessary.

Echinacea also is known as purple coneflowers, is a flowering plant of the genus Echinacea, belongings to the family Asteraceae, native to eastern and central North America. The herb has been used in traditional and herbal medicine to treat or prevent colds, flu, infections by stimulating the immune function, etc.

On finding a potential phytochemical for the treatment of chronic infectious diseases, researchers examined Echinacea extracts anti antioxidant activities.

According to the analysis of the three Echinacea extracts which were labeled as A, B, and C (A, roots of Echinacea purpurea L. Moench; B, roots, leaves, flowers, and seeds of Echinacea purpurea; C, aerial parts and roots of Echinacea purpurea and roots of Echinacea Angustifolia DC),

* Extract C showed higher density (0.97 g/mL), dry matter (0.23 g/mL), phenols (137.5 ± 2.3 mEAG/mL), flavonoids (0.62 ± 0.02 mEQ/mL), and caffeic acid (0.048 mg/L) compared to A and B.

* A, B presented 11 alkylamides, whereas C presented those 11 and three more.

* B decreased edema (40%) on day 2 similar to indomethacin. A and C showed hypoglycaemic activity similar to glibenclamide.


* The antiproliferative effect was only detected for C (IC50 270 μg/mL; 8171 μg/mL; 9338 μg/mL in HeLa, MCF-7, HCT-15, respectively).

In other words, the roots of Enchinanea showed the highest antioxidant profiles and capacity compared to the other parts of the plant.

After talking about other factors into account, researchers said, "The difference in the chemical and pharmacological properties among extracts highlights the need to consider strategies and policies for standardization of commercial herbal extracts in order to guarantee the safety and identity of this type of products".

Taken altogether, herbal echinacea may be considered adjunct therapies in the treatment of diseases associated with chronic inflammatory diseases, pending to the confirmation of the larger sample size and multicenter human study.

Intake of tocopherols in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Echinacea plants as antioxidant and antibacterial agents: From traditional medicine to biotechnological applications by Sharifi-Rad M1, Mnayer D2, Morais-Braga MFB3, Carneiro JNP3, Bezerra CF3, Coutinho HDM3, Salehi B4,5, Martorell M6, Del Mar Contreras M7, Soltani-Nejad A8, Uribe YAH9, Yousaf Z10, Iriti M11, Sharifi-Rad J. (PubMed)