Kidneys formed part of the secretory system, are bean-shaped organs located below the rib cage, one on each side of your spine with a function to filter out blood and remove waste through urinary secretion.
The kidney also plays a critical in maintaining the levels of fluids in the body, by removing extra fluids to make urine.
Furthermore, the kidney also regulates electrolytes, blood pressure, maintains acid-base balance, produces hormone calcitriol, renin, and erythropoietin.
Kidney diseases are a class of medical conditions associated with reduced function of the kidney, in cases, complete loss of kidney function such as kidney failure.
Chronic kidney disease, also known as chronic kidney failure, is a condition of a gradual loss of kidney function.
According to the observation of patients' data associated with the diseases, diabetes and high blood pressure are responsible for up to two-thirds of the cases.
According to the statistic, approximately, 30 million American adults have chronic kidney disease, and a large percentage of these people aren't aware of it. 1 in 3 American adults is at risk for kidney disease.
In other words, approximately 14 percent of the US population suffers some form of chronic kidney disease (CKD), including 661,000 cases of kidney failure.
Believe it or not, almost half of the individuals with CKD also have diabetes and/or self-reported cardiovascular disease (CVD).
Diabetes is a medical condition caused by long-term abnormally high blood glucose, leading to the damage of other tissue and organs, including the kidneys.
Another cause of chronic kidney disease is kidney disease. Early diagnosis of chronic kidney disease can often keep chronic kidney disease from getting worse.
Late diagnosis of chronic kidney disease may eventually lead to kidney failure, leading to dialysis or a kidney transplant to maintain life.
Omega-3 fatty acids are phytochemicals in the class of lipids, found abundantly in deepsea fisk, dark-green leafy vegetables, grains, legumes, nuts, etc.
The three main components of Omega-3 fatty acids are alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).
On finding a potential phytochemical for the treatment of kidneys, researchers evaluated the effects of the anti-inflammatory effect of omega-3 fatty acids on patients with chronic kidney disease(CKD).
By searching the medical literature on the database from inception to August 2016, including randomized controlled trials (RCTs) derived from multiple databases, and the effect of omega-3 fatty acids supplementation compared to control cohorts, researchers identified a total of 12 RCTs involving 487 patients were included in the meta-analysis.
Among 254 patients receiving omega-3 fatty acids and 233 patients served as controls who received placebo, there is
* There is no statistical significance in serum levels of C-reactive protein (CRP) (SMD, -0.20; 95% CI, -0.44 to 0.05; P = 0.11),
* The levels of pro-inflammatory cytokine IL-6 associated with the CKD showed insignificant change in both omega 3 and control groups.
* Additionally, chronic kidney disease (CKD) in the constitution of chronic inflammation through the expression of elevated levels of tumor necrosis factor-alpha (TNF-α) also showed insignificant changes in both groups.
Based on the findings, researchers suggested, "there is insufficient evidence to conclude the benefit of omega-3 fatty acids oral supplementation in reducing serum levels of CRP, IL-6, and TNF-α in patients with CKD".
In other words, omega-3 fatty acids may not be used for reducing complications of patients with CKD, pending the confirmation of the larger sample size and multicenter human study.
Intake of Omega-3 fatty acids in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Effects of Omega-3 Fatty Acids on Markers of Inflammation in Patients With Chronic Kidney Disease: A Controversial Issue by Hu C1, Yang M1, Zhu X1, Gao P1, Yang S1,2, Han Y1, Chen X1, Xiao L1, Yuan S1, Liu F1, Kanwar YS3,4, Sun L. (PubMed)
(2) Omega-3 fatty acids for dialysis vascular access outcomes in patients with chronic kidney disease by Tam KW1, Wu MY, Siddiqui FJ, Chan ES, Zhu Y, Jafar TH. (PubMed)
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