Colitis is a medical condition of inflammation of the large intestine, including the colon, caecum, and rectum.
Types of colitis according to the Catholic University of the Sacred Heart, are including
microscopic colitis, ischemic colitis, segmental colitis associated with diverticula, radiation colitis, diversion colitis, eosinophilic colitis, and Behcet's colitis.
There is no exact cause of colitis. Certain risk factors such as colon infection, inflammatory bowel disease (Crohn's disease, ulcerative colitis), ischemic colitis, allergic reactions, and microscopic colitis have been found to increase the risk of the onset of the condition.
The most common symptoms of colitis are totally depending on the types, including abdominal pain, cramping, diarrhea, with or without blood in the stool.
The most common risk factors associated with the onset of colitis are Medical conditions such as hypertension, diabetes, hyperlipidemia, and atrial fibrillation aging, genders, smoking, depression, and psychosocial stress and family history.
Other risk factors may also contribute to the incidence of colitis, according to the study by Service d'Epidémiologie et de Santé Publique, in a multivariate model are familial history of inflammatory bowel disease (odds ratio (OR) 4.3 (95% confidence interval 2.3-8)), breastfeeding (OR 2.1 (1.3-3.4)), bacille Calmette-Guerin vaccination (OR 3.6 (1.1-11.9)), and history of eczema (OR 2.1 (1-4.5)), disease during pregnancy (OR 8.9 (1.5-52)), and bedroom sharing (OR 7.1 (1.9-27.4)).
Conventionally, besides treating colitis with antibiotics, certain medications also are prescribed to improve the symptoms and quality of life of the patients, including anti-diarrheal medications.
Broccoli is a mustard/cabbage plant, belongings to the family Brassicaceae. The vegetable has large flower heads, usually green in color and the mass of flower heads is surrounded by leaves and evolved from a wild cabbage plant on the continent of Europe.
On finding a potential plant that process anti-colitis activity researchers compared the effects of broccoli-derived nanoparticle (BDN) and SFN on three mouse colitis models.
According to the data collected from the experiment, orally given nanoparticles isolated from broccoli extracts protected mice against colitis by-mediating the activation of 5'-adenylic acid-activated protein kinase (AMPK) associated with cellular energy homeostasis.
In the immune analysis, BDN prevented the dendritic cells (DCs) to act as messengers between the innate and the adaptive immune systems in dextran sulfate sodium (DSS)-induced colitis in C57BL/6 (B6) mice by targeting dendritic cells (DCs) activation and inducing DC tolerance.
Compared to BND, DCs pre-pulsed with SFN also prevented DSS-induced colitis in B6 mice,, similar to those of BND.
Taken altogether, broccoli derived nanoparticle (BDN) or SFN isolated from broccoli may be considered a functional food for the prevention and treatment of colitis, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Broccoli-Derived Nanoparticle Inhibits Mouse Colitis by Activating Dendritic Cell AMP-Activated Protein Kinase by Deng Z1, Rong Y1, Teng Y1, Mu J1, Zhuang X1, Tseng M2, Samykutty A1, Zhang L1, Yan J1, Miller D1, Suttles J1, Zhang HG. (PubMed)
(2) Environmental risk factors in paediatric inflammatory bowel diseases: a population based case control study by Baron S1, Turck D, Leplat C, Merle V, Gower-Rousseau C, Marti R, Yzet T, Lerebours E, Dupas JL, Debeugny S, Salomez JL, Cortot A, Colombel JF. (PubMed)
Ovarian Cyst Miracle (tm)
Permanently and Naturally, Eliminate All Types of Ovarian Cysts Within 2 Months
Monday, February 24, 2020
Sunday, February 23, 2020
Cucumber's Cucurbitacin B (CuB) Blocks the Skin Cancer Proliferation in Vitro
Skin cancer is a chronic and medical caused cell growth disorderly and uncontrollably due to the alternation of DNA.
Most cases of skin cancer begin in the cells on the surface of the inner lining, before proliferating to other tissues through cell cycle division.
Compared to normal cells with a limit of cycle division, the cancer cell can divide indefinitely. Some tumors can also stimulate the production of the new vessels to provide them with additional energy from the preexist vessel.
Most common types of skin cancer are
* Basal cell cancer
It is the most common type of skin cancer as a result of abnormal growth of the cells in the lowest layer of the epidermis, accounting for more than 90% of all skin cancer in the U.S.
* Squamous cell cancer
Squamous cell cancer arises from the uncontrolled multiplication of transformed malignant cells in the middle layer of the epidermis.
* Melanoma
Melanoma is a result of malignancy of melanocytes, which are the cell produced dark pigment for your skin.
Most common symptoms of skin cancer are abnormal skin patches, such as flat, scaly, brown or flesh-colored patches, a white, waxy scar-like sore, scaly red skin lesion, skin bump or lump, sore that won't heal, unintentional weight loss and non-healing ulcer, especially on lip or ears.
If you are experiencing some of the above symptoms, please make sure you check with your doctor to rule out the possibility.
The cucumber plant is a species of Cucumis Sativus, belongings to the family Cucurbitaceae and native to Western Asia. It is a creeping vine with roots in the ground and grows up with the support of frames.
With an aim to find a natural compound that processes anti-skin cancer property, researchers investigated the cucurbitacin B (CuB) effect, a major compound found in cucumber on cutaneous squamous cell carcinoma (CSCC).
According to the tested analysis, CuB inhibited 50% growth (ED50) of the CSCC cell lines (SRB1, SRB12, SCC13, COLO16) in liquid culture at 4 x 10(-7)-10(-5) M.
At 10(-7) M, CuB inhibited nearly all of the CSCC clonogenic cells used in the study through cell cycle arrest.
Interestingly, the injection of Cub exerted cancer cell morphologic changes within 60 min. Moreover, Cub (10(-8)-10(-6) M, 3-24 h) was effective in inhibiting the proteins associated with SRB1 and SRB12 cell lines proliferation by disrupting the cell cycle division.
The migration of SRB1 and SRB12 cells was also suppression by the injection of 10(-7) M CuB.
Most importantly, CuB exerted the synergistic potentiation of the anti-proliferative effect of cisplatin in CSCC.
In other words, CuB suppressed the cancer cell progression linearly in a dose-dependent manner through its G2/M cell cycle arrest
Based on the findings, researchers wrote, "CuB has a prominent anti-proliferative activity on CSCC cells".
Taken altogether, cucumber processed a high amount of CuB may be used for the treatment of skin cancer, pending to the confirmation of the larger sample size and multicenter human study.
Intake of CuB in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Cucurbitacin B inhibits growth, arrests the cell cycle, and potentiates antiproliferative efficacy of cisplatin in cutaneous squamous cell carcinoma cell lines by Chen W1, Leiter A, Yin D, Meiring M, Louw VJ, Koeffler HP. (PubMed)
Most cases of skin cancer begin in the cells on the surface of the inner lining, before proliferating to other tissues through cell cycle division.
Compared to normal cells with a limit of cycle division, the cancer cell can divide indefinitely. Some tumors can also stimulate the production of the new vessels to provide them with additional energy from the preexist vessel.
Most common types of skin cancer are
* Basal cell cancer
It is the most common type of skin cancer as a result of abnormal growth of the cells in the lowest layer of the epidermis, accounting for more than 90% of all skin cancer in the U.S.
* Squamous cell cancer
Squamous cell cancer arises from the uncontrolled multiplication of transformed malignant cells in the middle layer of the epidermis.
* Melanoma
Melanoma is a result of malignancy of melanocytes, which are the cell produced dark pigment for your skin.
Most common symptoms of skin cancer are abnormal skin patches, such as flat, scaly, brown or flesh-colored patches, a white, waxy scar-like sore, scaly red skin lesion, skin bump or lump, sore that won't heal, unintentional weight loss and non-healing ulcer, especially on lip or ears.
If you are experiencing some of the above symptoms, please make sure you check with your doctor to rule out the possibility.
The cucumber plant is a species of Cucumis Sativus, belongings to the family Cucurbitaceae and native to Western Asia. It is a creeping vine with roots in the ground and grows up with the support of frames.
With an aim to find a natural compound that processes anti-skin cancer property, researchers investigated the cucurbitacin B (CuB) effect, a major compound found in cucumber on cutaneous squamous cell carcinoma (CSCC).
According to the tested analysis, CuB inhibited 50% growth (ED50) of the CSCC cell lines (SRB1, SRB12, SCC13, COLO16) in liquid culture at 4 x 10(-7)-10(-5) M.
At 10(-7) M, CuB inhibited nearly all of the CSCC clonogenic cells used in the study through cell cycle arrest.
Interestingly, the injection of Cub exerted cancer cell morphologic changes within 60 min. Moreover, Cub (10(-8)-10(-6) M, 3-24 h) was effective in inhibiting the proteins associated with SRB1 and SRB12 cell lines proliferation by disrupting the cell cycle division.
The migration of SRB1 and SRB12 cells was also suppression by the injection of 10(-7) M CuB.
Most importantly, CuB exerted the synergistic potentiation of the anti-proliferative effect of cisplatin in CSCC.
In other words, CuB suppressed the cancer cell progression linearly in a dose-dependent manner through its G2/M cell cycle arrest
Based on the findings, researchers wrote, "CuB has a prominent anti-proliferative activity on CSCC cells".
Taken altogether, cucumber processed a high amount of CuB may be used for the treatment of skin cancer, pending to the confirmation of the larger sample size and multicenter human study.
Intake of CuB in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Cucurbitacin B inhibits growth, arrests the cell cycle, and potentiates antiproliferative efficacy of cisplatin in cutaneous squamous cell carcinoma cell lines by Chen W1, Leiter A, Yin D, Meiring M, Louw VJ, Koeffler HP. (PubMed)
Cucumber's cucurbitacin B (CuB) Processes Immune Modulatory and Anti-Inflammatory Properties
Inflammation is a natural defense of the human body against the invasion of harmful microorganisms.
In other words, the immune response of the first line defense macrophages after receiving information about skin or tissue damage from the brain stimulates the production of blood palette to cover the wound and pro-inflammatory cytokines to kill off invaders which may enter the body.
Most cases of the small wound are stoped in the acute phase of infection and the wound starts to heal itself.
In a large wound, some stitches are needed accompanying by the injection of antibiotics.
However, if the inflammation persists due to overexpression of proinflammatory cytokines, it can lead to the death of nearby healthy cells, causing the formation of scars.
In some cases, immune system response may also be compromised with the presence of harmful bacteria or viruses due to its inability to kill off all pathogens in a set period of time, leading to chronic low-grade inflammation.
The continued production of pro-inflammatory cytokines over the long-term can result in protein, lipid and cell damage and alternation of cell DNA causing the onset of diabetes, cardiovascular disease, and cancer.
Some researchers suggested without knowing more of the nature of the chronic low-grade inflammatory disease, the use of NSAIDs may cause harm to the patients.
Dr. Adler UC in the concerns about the use of NSAIDs for the treatment of chronic low-grade inflammatory disease, explained, "Pro-inflammatory cytokines and their chronic effect - low-grade inflammation - have been associated with diverse chronic conditions".
And, "current data on the role of pro-inflammatory cytokines and that the use of NSAIDs to treat chronic low-grade inflammation can produce a contrary, rebound effect, as anticipated by Hahnemann. By diverting from the "palliative action-rebound effect" course".
The cucumber plant is a species of Cucumis Sativus, belongings to the family Cucurbitaceae and native to Western Asia. It is a creeping vine with roots in the ground and grows up with the support of frames.
With an aim to find a natural compound that processes anti-inflammatory property, researchers investigated cucurbitacin B (CuB) effect, a major compound found in cucumber on parameters related to antigen presentation and T-cell activation.
On basal and lipopolysaccharide (LPS)-induced inflammation, CuB inhibited significantly the LPS-a expression of MHC II (antigen-presenting cells), CD40, CD54, and CD80 associated with immunodeficiency with hyper-IgM.
Furthermore, the injection of CuB also suppressed the production of intracellular reactive oxygen species and blocked the activation of pro-inflammatory mediators, such as nitric oxide (NO), prostaglandin E2, tumor necrosis factor-α, interleukin (IL)-6, IL-12, and IL-1β, without inducing any cytotoxicity.
The finding suggested that CuB possesses immunomodulatory and anti-inflammatory effects against disease involved in inflammation.
In other to reveal more information anti-inflammatory activity of CuB, researchers evaluated the chemical ability to scavenge free radicals such as hydroxyl radical, superoxide anions and singlet oxygen.
According to the tested assays, CuB exerted a broad spectrum radical-scavenging capacity surpasses those of grape-seed extract, wheat, alfalfa, and ginkgo Biloba extracts.
Cucurbitacins not only inhibited lipid peroxidation and oxidation but also exhibited the anti-inflammatory and analgesic properties through their derivatives 23, 24 dihydrocucurbitacin and cucurbitacin.
In other words, CuB inhibited the expression of TNF in macrophages and lymphocytes involved in immune response and the expression of pro-inflammatory mediators such as nitric-oxide synthase-2 and cyclooxygenase-2.
Dr. Olayinka Oridupa, the lead scientist said, "It is general knowledge among researchers working with natural medicinal products that any of the cucurbitacins have the attributes or the potential to become fully patented as an anti-inflammatory...drug".
Taken altogether, cucumber processed a high amount of CuB may be used for the treatment of inflammation, pending to the confirmation of the larger sample size and multicenter human study.
Intake of CuB in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Cucurbitacin B inhibits immunomodulatory function and the inflammatory response in macrophages by Kim M1, Park SY1, Jin ML1, Park G1,2, Son HJ. (PubMed)
(2) Search for a novel antioxidant, anti- inflammatory/analgesic or anti-proliferative drug: Cucurbitacins hold the ace by Adebowale Bernard Saba, and Olayinka Oridupa. (Research Gate)
(3) Low-grade inflammation in chronic diseases: an integrative pathophysiology anticipated by homeopathy? by Adler UC. (PubMed)
In other words, the immune response of the first line defense macrophages after receiving information about skin or tissue damage from the brain stimulates the production of blood palette to cover the wound and pro-inflammatory cytokines to kill off invaders which may enter the body.
Most cases of the small wound are stoped in the acute phase of infection and the wound starts to heal itself.
In a large wound, some stitches are needed accompanying by the injection of antibiotics.
However, if the inflammation persists due to overexpression of proinflammatory cytokines, it can lead to the death of nearby healthy cells, causing the formation of scars.
In some cases, immune system response may also be compromised with the presence of harmful bacteria or viruses due to its inability to kill off all pathogens in a set period of time, leading to chronic low-grade inflammation.
The continued production of pro-inflammatory cytokines over the long-term can result in protein, lipid and cell damage and alternation of cell DNA causing the onset of diabetes, cardiovascular disease, and cancer.
Some researchers suggested without knowing more of the nature of the chronic low-grade inflammatory disease, the use of NSAIDs may cause harm to the patients.
Dr. Adler UC in the concerns about the use of NSAIDs for the treatment of chronic low-grade inflammatory disease, explained, "Pro-inflammatory cytokines and their chronic effect - low-grade inflammation - have been associated with diverse chronic conditions".
And, "current data on the role of pro-inflammatory cytokines and that the use of NSAIDs to treat chronic low-grade inflammation can produce a contrary, rebound effect, as anticipated by Hahnemann. By diverting from the "palliative action-rebound effect" course".
The cucumber plant is a species of Cucumis Sativus, belongings to the family Cucurbitaceae and native to Western Asia. It is a creeping vine with roots in the ground and grows up with the support of frames.
With an aim to find a natural compound that processes anti-inflammatory property, researchers investigated cucurbitacin B (CuB) effect, a major compound found in cucumber on parameters related to antigen presentation and T-cell activation.
On basal and lipopolysaccharide (LPS)-induced inflammation, CuB inhibited significantly the LPS-a expression of MHC II (antigen-presenting cells), CD40, CD54, and CD80 associated with immunodeficiency with hyper-IgM.
Furthermore, the injection of CuB also suppressed the production of intracellular reactive oxygen species and blocked the activation of pro-inflammatory mediators, such as nitric oxide (NO), prostaglandin E2, tumor necrosis factor-α, interleukin (IL)-6, IL-12, and IL-1β, without inducing any cytotoxicity.
The finding suggested that CuB possesses immunomodulatory and anti-inflammatory effects against disease involved in inflammation.
In other to reveal more information anti-inflammatory activity of CuB, researchers evaluated the chemical ability to scavenge free radicals such as hydroxyl radical, superoxide anions and singlet oxygen.
According to the tested assays, CuB exerted a broad spectrum radical-scavenging capacity surpasses those of grape-seed extract, wheat, alfalfa, and ginkgo Biloba extracts.
Cucurbitacins not only inhibited lipid peroxidation and oxidation but also exhibited the anti-inflammatory and analgesic properties through their derivatives 23, 24 dihydrocucurbitacin and cucurbitacin.
In other words, CuB inhibited the expression of TNF in macrophages and lymphocytes involved in immune response and the expression of pro-inflammatory mediators such as nitric-oxide synthase-2 and cyclooxygenase-2.
Dr. Olayinka Oridupa, the lead scientist said, "It is general knowledge among researchers working with natural medicinal products that any of the cucurbitacins have the attributes or the potential to become fully patented as an anti-inflammatory...drug".
Taken altogether, cucumber processed a high amount of CuB may be used for the treatment of inflammation, pending to the confirmation of the larger sample size and multicenter human study.
Intake of CuB in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Cucurbitacin B inhibits immunomodulatory function and the inflammatory response in macrophages by Kim M1, Park SY1, Jin ML1, Park G1,2, Son HJ. (PubMed)
(2) Search for a novel antioxidant, anti- inflammatory/analgesic or anti-proliferative drug: Cucurbitacins hold the ace by Adebowale Bernard Saba, and Olayinka Oridupa. (Research Gate)
(3) Low-grade inflammation in chronic diseases: an integrative pathophysiology anticipated by homeopathy? by Adler UC. (PubMed)
Saturday, February 22, 2020
Phytochemical Alliin Protects The Heart Against the Risk Heart Attack (Myocardial Infarction)
Myocardial infarction or heart attack is a medical emergency caused by a reduced and stopped blood flow to the heart.
The most common symptoms of heart attacks are chest pain or discomfort that affects the shoulder, arm, back, neck, or jaw accompanied by shortness of breath, dizziness, faintness, or nausea.
Epidemiologically, episodes of angina are considered an early warning sign that a heart attack may be coming.
In angina, blood flow is stopped than restored, pain recedes within minutes, and the heart is not permanently damaged. However, in some cases, angina may cause some heart muscles to damage without affecting the heart functioning.
Unfortunately, heart attacks without any early warning signs were found in proximately 25% of the patients.
According to statistics, in the US, every year, approximately 790,000 Americans have a heart attack, including 580,000 cases of a first heart attack and 210,000 cases of a recurrent heart attack.
Dr. Fatemeh Kiani, the lead scientist in the examination of the risk factors involved in myocardial infarction said, "Results showed that 70% of patients were women and only 30% were men. 48% of them were illiterate and patients' mean age was 58.3".
And, "17% of patients (coronary artery diseases history), 25.5% (hypertension history), 26% (diabetes history), 15.5% (cholesterol history), 13% (smoking) and 3% have reported CABG history. The majority of people who referred had inferior MI (40.4%). 67.1% normal rhythm, 2.8% atrial fibrillation and 16% had ventricular tachycardia".
In other words, gender, aging, smoking and medical conditions associated with increased risk of heart disease are some of the most common risk factors found in patients with myocardial infarction.
Alliin (S-allyl-L-cysteine-S-oxide) is a phytochemical compound sulfoxide,. a derivative of the amino acid cysteine, belonging to the class of sulfur compounds, found abundantly in fresh garlic and onion.
On finding a potential compound for the prevention of heart attack, researchers examined S-allyl cysteine sulfoxide (SACS, alliin) preventive effect in isoproterenol (ISO)-induced myocardial ischemia in an animal model.
The study included male Wistar rats pretreated with SACS (40 and 80 mg kg(-1)) orally for 5 weeks followed by ISO (150 mg kg(-1)) administered subcutaneously at an interval of 24 h for 2 days.
The activities of beta-D-N-acetyl-glucosaminidase, beta-galactosidase, beta-glucosidase, and acid phosphatase in serum and the heart of ISO-induced rats.associated with mitochondrial dysfunction in the heart were increased substantially.
Furthermore, the declined of Na(+)K(+)-ATPase and increased Ca(2+)- and Mg(2+)-ATPases activity significantly (p < 0.05) associated with association of the risk of myocardial infarction were also found ISO-induced rats.
However, pretreatment of alliin 40 and 80 mg kg(-1)) showed a significant (p < 0.05) effect in all the aforementioned biochemical parameters.
In other words, alliin inhibited all risk factors involved in the onset of a heart attack.
In order to reveal more information about alliin anti hear attack activity, researchers investigated the preventive role of SACS on some biochemical parameters, glycoproteins, and hematology in experimentally induced myocardial infarction in rats.
Treatment of alliin followed by myocardial infarction induced in rats by subcutaneous injection of isoproterenol (ISO) (150 mg kg(-1)) at an interval of 24 h for 2 days, not only inhibited all parameters aforementioned study but also inhibited the levels/concentrations of glycoproteins in the heart.
Moreover, levels of pro-inflammation associated with immune response caused by ISO associated with the risk heart attacks were also significantly reduced by pretreatment of alliin.
Based on the results, Dr. Sangeetha T, the lead scientist said, "Oral pretreatment with SACS (40 and 80 mg kg(-1)) daily for a period of 35 days showed a positive effect on all the biochemical parameters studied in ISO-induced rats".
Taken altogether, alliin may be considered supplements for the prevention and treatment of myocardial infarction,, depending on the confirmation of the larger sample size and multicenter human study.
Intake of alliin in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Preventive effect of S-allyl cysteine sulfoxide (alliin) on lysosomal hydrolases and membrane-bound ATPases in isoproterenol-induced myocardial infarction in Wistar rats by Sangeetha T1, Darlin Quine S. (PubMed)
(2) Protective effect of S-allyl cysteine sulphoxide (alliin) on glycoproteins and hematology in isoproterenol induced myocardial infarction in male Wistar rats by Sangeetha T1, Quine SD. (PubMed)
(3) Assessment of Risk Factors in Patients With Myocardial Infarction by Fatemeh Kiani,1 Nasrin Hesabi,1 and Azizollah Arbabisarjou. (PMC)
The most common symptoms of heart attacks are chest pain or discomfort that affects the shoulder, arm, back, neck, or jaw accompanied by shortness of breath, dizziness, faintness, or nausea.
Epidemiologically, episodes of angina are considered an early warning sign that a heart attack may be coming.
In angina, blood flow is stopped than restored, pain recedes within minutes, and the heart is not permanently damaged. However, in some cases, angina may cause some heart muscles to damage without affecting the heart functioning.
Unfortunately, heart attacks without any early warning signs were found in proximately 25% of the patients.
According to statistics, in the US, every year, approximately 790,000 Americans have a heart attack, including 580,000 cases of a first heart attack and 210,000 cases of a recurrent heart attack.
Dr. Fatemeh Kiani, the lead scientist in the examination of the risk factors involved in myocardial infarction said, "Results showed that 70% of patients were women and only 30% were men. 48% of them were illiterate and patients' mean age was 58.3".
And, "17% of patients (coronary artery diseases history), 25.5% (hypertension history), 26% (diabetes history), 15.5% (cholesterol history), 13% (smoking) and 3% have reported CABG history. The majority of people who referred had inferior MI (40.4%). 67.1% normal rhythm, 2.8% atrial fibrillation and 16% had ventricular tachycardia".
In other words, gender, aging, smoking and medical conditions associated with increased risk of heart disease are some of the most common risk factors found in patients with myocardial infarction.
Alliin (S-allyl-L-cysteine-S-oxide) is a phytochemical compound sulfoxide,. a derivative of the amino acid cysteine, belonging to the class of sulfur compounds, found abundantly in fresh garlic and onion.
On finding a potential compound for the prevention of heart attack, researchers examined S-allyl cysteine sulfoxide (SACS, alliin) preventive effect in isoproterenol (ISO)-induced myocardial ischemia in an animal model.
The study included male Wistar rats pretreated with SACS (40 and 80 mg kg(-1)) orally for 5 weeks followed by ISO (150 mg kg(-1)) administered subcutaneously at an interval of 24 h for 2 days.
The activities of beta-D-N-acetyl-glucosaminidase, beta-galactosidase, beta-glucosidase, and acid phosphatase in serum and the heart of ISO-induced rats.associated with mitochondrial dysfunction in the heart were increased substantially.
Furthermore, the declined of Na(+)K(+)-ATPase and increased Ca(2+)- and Mg(2+)-ATPases activity significantly (p < 0.05) associated with association of the risk of myocardial infarction were also found ISO-induced rats.
However, pretreatment of alliin 40 and 80 mg kg(-1)) showed a significant (p < 0.05) effect in all the aforementioned biochemical parameters.
In other words, alliin inhibited all risk factors involved in the onset of a heart attack.
In order to reveal more information about alliin anti hear attack activity, researchers investigated the preventive role of SACS on some biochemical parameters, glycoproteins, and hematology in experimentally induced myocardial infarction in rats.
Treatment of alliin followed by myocardial infarction induced in rats by subcutaneous injection of isoproterenol (ISO) (150 mg kg(-1)) at an interval of 24 h for 2 days, not only inhibited all parameters aforementioned study but also inhibited the levels/concentrations of glycoproteins in the heart.
Moreover, levels of pro-inflammation associated with immune response caused by ISO associated with the risk heart attacks were also significantly reduced by pretreatment of alliin.
Based on the results, Dr. Sangeetha T, the lead scientist said, "Oral pretreatment with SACS (40 and 80 mg kg(-1)) daily for a period of 35 days showed a positive effect on all the biochemical parameters studied in ISO-induced rats".
Taken altogether, alliin may be considered supplements for the prevention and treatment of myocardial infarction,, depending on the confirmation of the larger sample size and multicenter human study.
Intake of alliin in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Preventive effect of S-allyl cysteine sulfoxide (alliin) on lysosomal hydrolases and membrane-bound ATPases in isoproterenol-induced myocardial infarction in Wistar rats by Sangeetha T1, Darlin Quine S. (PubMed)
(2) Protective effect of S-allyl cysteine sulphoxide (alliin) on glycoproteins and hematology in isoproterenol induced myocardial infarction in male Wistar rats by Sangeetha T1, Quine SD. (PubMed)
(3) Assessment of Risk Factors in Patients With Myocardial Infarction by Fatemeh Kiani,1 Nasrin Hesabi,1 and Azizollah Arbabisarjou. (PMC)
3,3'-Diindolylmethane May Induce immune-Toxicity if Overdosed
The immune system is the set of cells and their activity against antigens or infectious agents that comprises the body's defense system against diseases. The immune system does a great job of keeping people healthy and preventing infections.
It is one of the body's defense system against diseases.
Immune dysfunction is a chronic condition, depending on the parts of the immune system affected.
There are 2 types of immune dysfunction
* The underactive immune system is also known as the weakened immune system. People with the underactive immune system are susceptible to infection, recurrent infections.
The most common symptoms of the underactive immune system are infection including frequent and recurrent pneumonia, bronchitis, sinus infections, ear infections, meningitis or skin infections and Inflammation and infection of internal organs.
However, blood disorders, such as low platelet counts or anemia and digestive dysfunction are also some of the common symptoms found in patients with the underactive immune system.
* The overactive immune system is also known as autoimmune diseases. In this case, patients suffer diseases associated with the immune system that attacks the body tissues.
Immunomodulation is an action with a profound and positive effect in regulated immune response and function through activation of antibody formation or the inhibition of white blood cell activity.
On finding a potential plant that enhances immune functioning, researchers compared the effects of 3,3'-Diindolylmethane (DIM), a major product of indole-3-Carbinol isolated from genus Brassica, on various immune-modulatory activity in animal models and in vitro studies.
3,3'-Diindolylmethane or DIM are phytochemicals derived from the digestion of indole-3-carbinol, belonging to the group of Indoles, found abundantly in broccoli, Brussels sprouts, cabbage, and kale, etc.
According to the tested analysis, the DIM treatment showed multiple immunotoxic effects in decreasing in various immune cells (F4/80(+), CD11c(+), CD19(+), and CD3(+) cells) in the spleen.
Furthermore, the DIM treatment also induced the expression of splenic white pulp atrophy, an increase in immune cell apoptosis, and decreased expression of various toll-like receptors (TLRs), a class of proteins that play a key role in the innate immune system.
The action of 3,3'-Diindolylmethane that modulates the immune functioning was attributed to the promotion of the caspase-3 activity and ratio of proteins associated with cell deaths and survivals in regulating programmed cell death or apoptosis.
Based on the findings, researchers said, "This new information about the immunotoxic roles of DIM in a newborn mouse model may provide valuable clues for the development of a safe supplement, especially one designed for human infants".
Taken altogether, DIM supplements may process immune toxic activity if overdosed.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) 3,3'-Diindolylmethane induces immunotoxicity via splenocyte apoptosis in neonatal mice by Roh YS1, Cho A, Islam MR, Cho SD, Kim J, Kim JH, Lee JW, Lim CW, Kim B. (PubMed)
It is one of the body's defense system against diseases.
Immune dysfunction is a chronic condition, depending on the parts of the immune system affected.
There are 2 types of immune dysfunction
* The underactive immune system is also known as the weakened immune system. People with the underactive immune system are susceptible to infection, recurrent infections.
The most common symptoms of the underactive immune system are infection including frequent and recurrent pneumonia, bronchitis, sinus infections, ear infections, meningitis or skin infections and Inflammation and infection of internal organs.
However, blood disorders, such as low platelet counts or anemia and digestive dysfunction are also some of the common symptoms found in patients with the underactive immune system.
* The overactive immune system is also known as autoimmune diseases. In this case, patients suffer diseases associated with the immune system that attacks the body tissues.
Immunomodulation is an action with a profound and positive effect in regulated immune response and function through activation of antibody formation or the inhibition of white blood cell activity.
On finding a potential plant that enhances immune functioning, researchers compared the effects of 3,3'-Diindolylmethane (DIM), a major product of indole-3-Carbinol isolated from genus Brassica, on various immune-modulatory activity in animal models and in vitro studies.
3,3'-Diindolylmethane or DIM are phytochemicals derived from the digestion of indole-3-carbinol, belonging to the group of Indoles, found abundantly in broccoli, Brussels sprouts, cabbage, and kale, etc.
According to the tested analysis, the DIM treatment showed multiple immunotoxic effects in decreasing in various immune cells (F4/80(+), CD11c(+), CD19(+), and CD3(+) cells) in the spleen.
Furthermore, the DIM treatment also induced the expression of splenic white pulp atrophy, an increase in immune cell apoptosis, and decreased expression of various toll-like receptors (TLRs), a class of proteins that play a key role in the innate immune system.
The action of 3,3'-Diindolylmethane that modulates the immune functioning was attributed to the promotion of the caspase-3 activity and ratio of proteins associated with cell deaths and survivals in regulating programmed cell death or apoptosis.
Based on the findings, researchers said, "This new information about the immunotoxic roles of DIM in a newborn mouse model may provide valuable clues for the development of a safe supplement, especially one designed for human infants".
Taken altogether, DIM supplements may process immune toxic activity if overdosed.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) 3,3'-Diindolylmethane induces immunotoxicity via splenocyte apoptosis in neonatal mice by Roh YS1, Cho A, Islam MR, Cho SD, Kim J, Kim JH, Lee JW, Lim CW, Kim B. (PubMed)
Friday, February 21, 2020
Omega-3 Fatty Acids May Process Anti Chronic Diseases and Cardiovascular Disease (CVD Activity
Chronic diseases are medical conditions that last more than 3 months depending on the type of diseases.
In other words, chronic diseases generally cannot be prevented or cured by medication, nor do they just disappear.
According to the statistics, chronic diseases affect millions of people worldwide, leading to the death of 35 million people in 2005, including many young people and those in middle age.
Cardiovascular disease (CVD) is a group of conditions associated with the heart and blood vessels.
Heart disease is a class of diseases associated with interruption of blood flow in the blood vessel or damage of the heart tissue, including coronary artery diseases (CAD) such as angina and myocardial infarction.
According to the statistics, heart disease is a leading cause of death in the US. Approximately 2000 people in the general population die of heart disease every day.
Coronary heart disease (CHD) is the most common type of heart disease, that kills over 370,000 people annually.
The causes of cardiovascular diseases are associated with the accumulation of plaques in the arteries, impeding the blood flow which carries the nutrients and oxygen to the heart, causing damage to the heart tissue and reduced function of the arteries.
In other words, high blood pressure, high blood cholesterol, smoking, diabetes, weight, depression and family history associated with the early onset of plaques accumulated and impeding function of the arteries are the prevalent risk factors of cardiovascular diseases.
According to the statistic cardiovascular disease is the leading cause of death in women in the US with 90% of women having one risk factor.
Believe it or not, women are 4 times more likely to die from heart disease than breast cancer and 2/3 of women are not aware of heart disease is such a risk for them, according to the Jean Hailes for Women Health in the article cardiovascular health.
Many people know that tobacco use is associated with an increased risk of bladder cancer, but most of them do not know that smoking is one of the leading causes of cardiovascular diseases.
Omega-3 fatty acids are phytochemicals in the class of lipids, found abundantly in deepsea fisk, dark-green leafy vegetables, grains, legumes, nuts, etc.
The three main components of Omega-3 fatty acids are alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).
On finding a potential phytochemical for the treatment of chronic diseases, researchers examined the
importance of the omega-6/omega-3 fatty acid ratio in patients with cardiovascular disease and other chronic diseases.
According to the results of the experiment, excessive amounts of omega-6 polyunsaturated fatty acids (PUFA) and a very high omega-6/omega-3 ratio has been found to induce the pathogenesis of many diseases, including cardiovascular disease, cancer, and inflammatory and autoimmune disease.
Increased levels of omega-3 PUFA with the lower of omega-6 PUFA (a lower omega-6/omega-3 ratio), exerted the protective effects.
The ratio of omega-3 and omega-6 PUFA of 1/4 are associated with a reduced risk of cardiovascular diseases.
A ratio of 2.5/1 showed strong activity in reducing rectal cell proliferation in patients with colorectal cancer.
Furthermore, the lower omega-6/omega-3 ratio was associated with a decreased risk of CVD in women with breast cancer.
Most importantly, a ratio of 2-3/1 suppressed inflammation in patients with rheumatoid arthritis and a ratio of 5/1 had a beneficial effect on patients with asthma, whereas a ratio of 10/1 had adverse consequences.
Based on the findings, researchers said, " it is quite possible that the therapeutic dose of omega-3 fatty acids will depend on the degree of severity of disease resulting from the genetic predisposition".
And " A lower ratio of omega-6/omega-3 fatty acids is more desirable in reducing the risk of many of the chronic diseases of high prevalence in Western societies, as well as in the developing countries".
Taken altogether, Omega-3 fatty acids together with low levels of omega-6 fatty acid may be considered a functional food for the prevention and treatment of chronic diseases and CVD, pending to the confirmation of the larger sample size and multicenter human study.
Intake of Omega-3 fatty acids in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) The importance of the omega-6/omega-3 fatty acid ratio in cardiovascular disease and other chronic diseases by Simopoulos AP. (PubMed)
In other words, chronic diseases generally cannot be prevented or cured by medication, nor do they just disappear.
According to the statistics, chronic diseases affect millions of people worldwide, leading to the death of 35 million people in 2005, including many young people and those in middle age.
Cardiovascular disease (CVD) is a group of conditions associated with the heart and blood vessels.
Heart disease is a class of diseases associated with interruption of blood flow in the blood vessel or damage of the heart tissue, including coronary artery diseases (CAD) such as angina and myocardial infarction.
According to the statistics, heart disease is a leading cause of death in the US. Approximately 2000 people in the general population die of heart disease every day.
Coronary heart disease (CHD) is the most common type of heart disease, that kills over 370,000 people annually.
The causes of cardiovascular diseases are associated with the accumulation of plaques in the arteries, impeding the blood flow which carries the nutrients and oxygen to the heart, causing damage to the heart tissue and reduced function of the arteries.
In other words, high blood pressure, high blood cholesterol, smoking, diabetes, weight, depression and family history associated with the early onset of plaques accumulated and impeding function of the arteries are the prevalent risk factors of cardiovascular diseases.
According to the statistic cardiovascular disease is the leading cause of death in women in the US with 90% of women having one risk factor.
Believe it or not, women are 4 times more likely to die from heart disease than breast cancer and 2/3 of women are not aware of heart disease is such a risk for them, according to the Jean Hailes for Women Health in the article cardiovascular health.
Many people know that tobacco use is associated with an increased risk of bladder cancer, but most of them do not know that smoking is one of the leading causes of cardiovascular diseases.
Omega-3 fatty acids are phytochemicals in the class of lipids, found abundantly in deepsea fisk, dark-green leafy vegetables, grains, legumes, nuts, etc.
The three main components of Omega-3 fatty acids are alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).
On finding a potential phytochemical for the treatment of chronic diseases, researchers examined the
importance of the omega-6/omega-3 fatty acid ratio in patients with cardiovascular disease and other chronic diseases.
According to the results of the experiment, excessive amounts of omega-6 polyunsaturated fatty acids (PUFA) and a very high omega-6/omega-3 ratio has been found to induce the pathogenesis of many diseases, including cardiovascular disease, cancer, and inflammatory and autoimmune disease.
Increased levels of omega-3 PUFA with the lower of omega-6 PUFA (a lower omega-6/omega-3 ratio), exerted the protective effects.
The ratio of omega-3 and omega-6 PUFA of 1/4 are associated with a reduced risk of cardiovascular diseases.
A ratio of 2.5/1 showed strong activity in reducing rectal cell proliferation in patients with colorectal cancer.
Furthermore, the lower omega-6/omega-3 ratio was associated with a decreased risk of CVD in women with breast cancer.
Most importantly, a ratio of 2-3/1 suppressed inflammation in patients with rheumatoid arthritis and a ratio of 5/1 had a beneficial effect on patients with asthma, whereas a ratio of 10/1 had adverse consequences.
Based on the findings, researchers said, " it is quite possible that the therapeutic dose of omega-3 fatty acids will depend on the degree of severity of disease resulting from the genetic predisposition".
And " A lower ratio of omega-6/omega-3 fatty acids is more desirable in reducing the risk of many of the chronic diseases of high prevalence in Western societies, as well as in the developing countries".
Taken altogether, Omega-3 fatty acids together with low levels of omega-6 fatty acid may be considered a functional food for the prevention and treatment of chronic diseases and CVD, pending to the confirmation of the larger sample size and multicenter human study.
Intake of Omega-3 fatty acids in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) The importance of the omega-6/omega-3 fatty acid ratio in cardiovascular disease and other chronic diseases by Simopoulos AP. (PubMed)
Cruciferous Vegetables Inhibit the Expression of Oxidative Stress in Parkinson's disease (PD)
Antioxidants are stable molecules with a unique function in the inhibition of oxidation.
Oxidative stress is a condition caused by an imbalance of the ratio of free radicals and antioxidants in the body.
In other words, oxidative stress is either caused by overexpression of free radical or depletion of antioxidant enzymes in the body.
Some researchers suggested that oxidative stress may also arise due to the chain reaction of free radicals in which free radicals donate or intercept an electron from other stable molecules.
This chain of reaction is the cause of oxidative stress, a condition is associated with either overexpression of free radicals or depletion of antioxidant enzymes produced by the host organs.
Overexpression of free radicals is known to cause damage in contributing to the etiology of many chronic health problems such as cardiovascular and inflammatory disease, cataracts, and cancer.
Long-term oxidative stress presented in the body can cause protein and lipid damage and alternation of cell DNA, leading to the onset of chronic diseases, including cardiovascular disease, diabetes, and cancer.
More precisely, exogenous factors, such as cigarette smoke, and endogenous factors, such as the oxidative burst from activated macrophages are some of the factors involved in the risk of oxidative stress.
Free radicals are highly reactive molecules with an unpaired electron on the outer ring of the atom.
Due to its nature to become stable, free radicals readily to donate or steal an electron from other molecules, leading to the chain of domino's effect that can not be stopped until either the electrons are paired or inhibited by antioxidants.
Parkinson's disease is a progressive neurodegenerative disease that affects movement caused by the gradual death of neurons that produce a chemical messenger in the brain called dopamine.
Cruciferous vegetables are a group of vegetables, belongings to the family Brassicaceae (also called Cruciferae) with many genera, species, and cultivated all over the world in suitable climate for commercial profits, including cauliflower, cabbage, kale, garden cress, bok choy, broccoli, Brussels sprouts, and green leafy vegetables.
On finding a potential herbal medicine for the prevention and treatment of chronic diseases, researchers examined the antioxidant Dithiolethiones, a group of sulfur-containing heterocyclic compounds found in cruciferous vegetables protective effects against oxidative stress.
According to the tested analysis, in 6-hydroxydopamine (6-OHDA) Parkinson's disease (PD) model
* Before treatment of ACDT, cells treated by 6-OHDA showed to induce cell death, reduce the cell respiration, elevate the caspase associated with apoptosis, and increase of the levels of reactive oxygen species.
In other words, 6-hydroxydopamine (6-OHDA) reduces neuron integrity and promotes neuron apoptosis to induce PD neurodegenerative disease.
* Pretreatment of SH-SY5Y cells with dithiole-4-carboxylic acid ethyl ester (ACDT), a derivative of Dithiolethiones induced the production of the levels of the antioxidant glutathione (GSH) in a time-concentration-dependent manner by inhibiting the GSH-synthesizing enzyme glutamate-cysteine ligase catalytic subunit (GCLC).
* Furthermore, the application of ACDT also promoted the expression of antioxidant through the activity of nuclear factor erythroid-2 related factor (Nrf2), that protect the cells against oxidative damage triggered by injury and inflammation.
Based on the findings, researchers wrote, "Collectively, the data demonstrated ACDT to be a promising new dithiolethione for the treatment of PD, with two modifiable functional groups offering additional avenues for enhanced pharmacological application",
Taken altogether, Cruciferous vegetables processed abundantly phytochemical dithiolethionede may be considered a functional herb for the prevention and treatment of PD, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Disubstituted Dithiolethione ACDT Exerts Neuroprotective Effects Against 6-Hydroxydopamine-Induced Oxidative Stress in SH-SY5Y Cells by Betharia S1, Rondόn-Ortiz AN2, Brown DA. (PubMed)
Oxidative stress is a condition caused by an imbalance of the ratio of free radicals and antioxidants in the body.
In other words, oxidative stress is either caused by overexpression of free radical or depletion of antioxidant enzymes in the body.
Some researchers suggested that oxidative stress may also arise due to the chain reaction of free radicals in which free radicals donate or intercept an electron from other stable molecules.
This chain of reaction is the cause of oxidative stress, a condition is associated with either overexpression of free radicals or depletion of antioxidant enzymes produced by the host organs.
Overexpression of free radicals is known to cause damage in contributing to the etiology of many chronic health problems such as cardiovascular and inflammatory disease, cataracts, and cancer.
Long-term oxidative stress presented in the body can cause protein and lipid damage and alternation of cell DNA, leading to the onset of chronic diseases, including cardiovascular disease, diabetes, and cancer.
More precisely, exogenous factors, such as cigarette smoke, and endogenous factors, such as the oxidative burst from activated macrophages are some of the factors involved in the risk of oxidative stress.
Free radicals are highly reactive molecules with an unpaired electron on the outer ring of the atom.
Due to its nature to become stable, free radicals readily to donate or steal an electron from other molecules, leading to the chain of domino's effect that can not be stopped until either the electrons are paired or inhibited by antioxidants.
Parkinson's disease is a progressive neurodegenerative disease that affects movement caused by the gradual death of neurons that produce a chemical messenger in the brain called dopamine.
Cruciferous vegetables are a group of vegetables, belongings to the family Brassicaceae (also called Cruciferae) with many genera, species, and cultivated all over the world in suitable climate for commercial profits, including cauliflower, cabbage, kale, garden cress, bok choy, broccoli, Brussels sprouts, and green leafy vegetables.
On finding a potential herbal medicine for the prevention and treatment of chronic diseases, researchers examined the antioxidant Dithiolethiones, a group of sulfur-containing heterocyclic compounds found in cruciferous vegetables protective effects against oxidative stress.
According to the tested analysis, in 6-hydroxydopamine (6-OHDA) Parkinson's disease (PD) model
* Before treatment of ACDT, cells treated by 6-OHDA showed to induce cell death, reduce the cell respiration, elevate the caspase associated with apoptosis, and increase of the levels of reactive oxygen species.
In other words, 6-hydroxydopamine (6-OHDA) reduces neuron integrity and promotes neuron apoptosis to induce PD neurodegenerative disease.
* Pretreatment of SH-SY5Y cells with dithiole-4-carboxylic acid ethyl ester (ACDT), a derivative of Dithiolethiones induced the production of the levels of the antioxidant glutathione (GSH) in a time-concentration-dependent manner by inhibiting the GSH-synthesizing enzyme glutamate-cysteine ligase catalytic subunit (GCLC).
* Furthermore, the application of ACDT also promoted the expression of antioxidant through the activity of nuclear factor erythroid-2 related factor (Nrf2), that protect the cells against oxidative damage triggered by injury and inflammation.
Based on the findings, researchers wrote, "Collectively, the data demonstrated ACDT to be a promising new dithiolethione for the treatment of PD, with two modifiable functional groups offering additional avenues for enhanced pharmacological application",
Taken altogether, Cruciferous vegetables processed abundantly phytochemical dithiolethionede may be considered a functional herb for the prevention and treatment of PD, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Disubstituted Dithiolethione ACDT Exerts Neuroprotective Effects Against 6-Hydroxydopamine-Induced Oxidative Stress in SH-SY5Y Cells by Betharia S1, Rondόn-Ortiz AN2, Brown DA. (PubMed)
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