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Friday, February 21, 2020

Omega-3 Fatty Acids May Process Anti Chronic Diseases and Cardiovascular Disease (CVD Activity

Chronic diseases are medical conditions that last more than 3 months depending on the type of diseases.

In other words, chronic diseases generally cannot be prevented or cured by medication, nor do they just disappear.

According to the statistics, chronic diseases affect millions of people worldwide, leading to the death of 35 million people in 2005, including many young people and those in middle age.
Cardiovascular disease (CVD) is a group of conditions associated with the heart and blood vessels.

Heart disease is a class of diseases associated with interruption of blood flow in the blood vessel or damage of the heart tissue, including coronary artery diseases (CAD) such as angina and myocardial infarction.

According to the statistics, heart disease is a leading cause of death in the US. Approximately 2000 people in the general population die of heart disease every day.

Coronary heart disease (CHD) is the most common type of heart disease, that kills over 370,000 people annually.

The causes of cardiovascular diseases are associated with the accumulation of plaques in the arteries, impeding the blood flow which carries the nutrients and oxygen to the heart, causing damage to the heart tissue and reduced function of the arteries.

In other words, high blood pressure, high blood cholesterol, smoking, diabetes, weight, depression and family history associated with the early onset of plaques accumulated and impeding function of the arteries are the prevalent risk factors of cardiovascular diseases.

According to the statistic cardiovascular disease is the leading cause of death in women in the US with 90% of women having one risk factor.

Believe it or not, women are 4 times more likely to die from heart disease than breast cancer and 2/3 of women are not aware of heart disease is such a risk for them, according to the Jean Hailes for Women Health in the article cardiovascular health.

Many people know that tobacco use is associated with an increased risk of bladder cancer, but most of them do not know that smoking is one of the leading causes of cardiovascular diseases.

Omega-3 fatty acids are phytochemicals in the class of lipids, found abundantly in deepsea fisk, dark-green leafy vegetables, grains, legumes, nuts, etc.


The three main components of Omega-3 fatty acids are alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).

On finding a potential phytochemical for the treatment of chronic diseases, researchers examined the
importance of the omega-6/omega-3 fatty acid ratio in patients with cardiovascular disease and other chronic diseases.

According to the results of the experiment, excessive amounts of omega-6 polyunsaturated fatty acids (PUFA) and a very high omega-6/omega-3 ratio has been found to induce the pathogenesis of many diseases, including cardiovascular disease, cancer, and inflammatory and autoimmune disease.

Increased levels of omega-3 PUFA with the lower of omega-6 PUFA (a lower omega-6/omega-3 ratio), exerted the protective effects.

The ratio of omega-3 and omega-6 PUFA of 1/4 are associated with a reduced risk of cardiovascular diseases.

A ratio of 2.5/1 showed strong activity in reducing rectal cell proliferation in patients with colorectal cancer.

Furthermore, the lower omega-6/omega-3 ratio was associated with a decreased risk of CVD in women with breast cancer.

Most importantly, a ratio of 2-3/1 suppressed inflammation in patients with rheumatoid arthritis and a ratio of 5/1 had a beneficial effect on patients with asthma, whereas a ratio of 10/1 had adverse consequences.

Based on the findings, researchers said, " it is quite possible that the therapeutic dose of omega-3 fatty acids will depend on the degree of severity of disease resulting from the genetic predisposition".

And " A lower ratio of omega-6/omega-3 fatty acids is more desirable in reducing the risk of many of the chronic diseases of high prevalence in Western societies, as well as in the developing countries".


Taken altogether, Omega-3 fatty acids together with low levels of omega-6 fatty acid may be considered a functional food for the prevention and treatment of chronic diseases and CVD, pending to the confirmation of the larger sample size and multicenter human study.

Intake of Omega-3 fatty acids in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) The importance of the omega-6/omega-3 fatty acid ratio in cardiovascular disease and other chronic diseases by Simopoulos AP. (PubMed)

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