Infection is an inflammatory condition caused by a microbial invasion on body tissues
Most cases of bacterial infection are treated with antibiotics. However, bacteria are very adaptable, overuse of antibiotics has been found to make them resistant to antibiotics.
The most common symptoms of bacterial infection include redness and heat, swelling, fever, pain at the site of infection.
Out of trillions of strains of bacteria in the world, only a few cause diseases in humans. Believe it or not, our gut contains trillion microorganisms, most of them are bacteria.
Infection can be acute or chronic. In the acute phase of infection. The immune macrophages in the first line of defense stimulate the production of blood palette to cover the wound and pro-inflammatory cytokines to the site of the infection to kill off pathogens.
However, overproduction of pro-inflammatory cytokines in the acute phase of infection has also killed off or damage to the nearby healthy cells, leading to the formation of scars.
Symptoms of the acute infection include gastrointestinal discomforts, such as congestion vomiting or nausea, and diarrhea, short term joint or muscle pain, fever, headache, skin rash and cough, Some patients with acute infection also experience symptoms of swollen lymph nodes, an indication of the body is fighting infection.
In most cases in a healthy individual, depending on the size of the wound, the immune system can easily eradicate all foreign invaders and the wound is recovered within days and weeks.
In chronic infection, the symptoms are most vague or no specific symptoms, including bronchitis and asthma, persistent low-grade chronic joint and muscle pain, or swelling and the alternations between diarrhea and constipation, bloating, or heartburn, In other words, the symptoms are totally depended on the location of the low-grade inflammation.
Beta-Sitosterol is a phytochemical in the class of Phytosterols, belongings to the group of Lipids, found abundantly in avocados, rice bran, wheat germ, corn oils, fennel, peanuts, soybeans, hawthorn, basil, buckwheat. etc.
On finding a potential phytochemical for the prevention and treatment of infectious diseases, researchers examined the antibacterial activity of compounds from the powder of root bark of Malva parviflora (Malvaceae).
According to the chemical analysis of the extracts with petroleum ether (b.p. 60–80 °C), chloroform and ethanol, the chloroform extract showed antibacterial activity against Staphylococcus aureus and Escherichia coli compared to the effect of the ethanolic extract against only S. aureus.
The chloroform extract inhibited the bacterial strain properties were characterized as β-sitosterol by physical properties, chemical test, spectral analysis (FTIR, NMR, and MS) and compared the data obtained from the literature.
In other words, phytochemical β-sitosterol prompted a strong anti-bacterial activity of root bark of Malva parviflora (Malvaceae)
Taken altogether, beta-Sitosterol may be considered a supplement for the prevention and treatment of bacterial infectious diseases, pending to the confirmation of the larger sample size and multicenter human study.
Intake of beta-Sitosterol in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Souces
(1) Structure elucidation of β-sitosterol with antibacterial activity from the root bark of Malvaparviflora by Mesfin Medihin Ododo,
1 Manash Kumar Choudhury,2 and Ahmed Hussen Dekebo. (PMC)
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