Diabetes is a chronic condition caused by insufficient insulin entering the bloodstream to regulate the glucose.
In other words, diabetes occurs when cells in the pancreas dying off or receptor sites clogged up by fat and cholesterol. In some cases, diabetes is also caused by allergic reactions of cells in the immune system.
Type 2 diabetes is a medical condition characterized by insufficient insulin entering the bloodstream to regulate glucose due to either cell in the pancreas dying off or receptor sites clogged up by fat and cholesterol.
Researchers do not know what causes the pancreas to die off or receptor sites clogged up. However, they do know obesity or overweight, gender, ethnicity, age, family history, gestation diabetes, are associated with an increased risk of type 2 diabetes.
Some researchers also suggested that people with certain medical conditions such as polycystic ovary syndrome. and high blood pressure is more prone to the onset of the disease.
The most common symptoms of diabetes are excessive thirst and hunger, frequent urination, unintended weight loss or gain, frequent fatigue, irritability and gastrointestinal symptoms such as nausea.
In severe cases, patients may also experience symptoms of blurred vision and slow wound healing or ulcer.
Hyperglycemia, a medical condition of abnormally high blood glucose, is a major concern, in people with both type 1 and type 2 diabetes.
Most cases of hyperglycemia occurred in patients who do not manage their diabetes properly.
Hyperglycemia, a hallmark of diabetes has been found to induce diabetics complications, including neuropathy, nephropathy, and retinopathy). ...
On finding a natural ingredient for the prevention and treatment of chronic diseases associated with oxidative stress, scientists examined the effects of bioactive peptide fractions from de-hulled hard-to-cook (HTC) bean on enzyme targets of type-2 diabetes and oxidative stress.
The tested Protein isolated from Pinto Durango and Negro 8025 beans were hydrolyzed (120min) with either alcalase® or bromelain and separated into five peptide fractions.
Pinto bean is also known as common bean, genus Phaseolus and the family Fabaceae. It has a mottled appearance of darker reddish-brown spots on a lighter brownish beige background, thus appearing painted or spotted.
According to tested analysis,
* The <1kDa pinto Durango-bromelain fraction showed the best inhibition of α-amylase (49.9±1.4%) associated with the causes of hyperglycemia and development of type 2 diabetes.
* Furthermore, the <1kDa pinto Durango-alcalase fraction inhibited both, α-glucosidase (76.4±0.5%), and dipeptidyl peptidase-IV (DPP-IV, 55.3±1.6%) involved in the elevated blood glucose levels.
* Hydrolysates and peptide fractions showed antioxidant capacity (ORAC: 159.6±2.9 to 932.6±1.1mmolTE/g) and nitric oxide inhibition (57.5±0.9 to 68.3±4.2%) that inhibit the overexpression of oxidative stress found in type 2 diabetics.
* Moreover, the hydrolysates and fractions <1 and 1-3kDa were able to increase glucose-stimulated insulin secretion from iNS-1E cells up to 57%, compared to glucose control.
Based on the results, researchers suggest, " Hydrolysates from HTC beans inhibited enzymes related to diabetes management, being the smallest peptides (<1kDa) the most potent. HTC bean could be a source of protein to produce bioactive peptides with potential antidiabetic properties".
Taken altogether, Pinto beans may process antioxidant and anti-diabetes properties, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Hard-to-cook bean (Phaseolus vulgaris L.) proteins hydrolyzed by alcalase and bromelain produced bioactive peptide fractions that inhibit targets of type-2 diabetes and oxidative stress by Oseguera-Toledo ME1, Gonzalez de Mejia E2, Amaya-Llano SL. (PubMed)
Ovarian Cyst Miracle (tm)
Permanently and Naturally, Eliminate All Types of Ovarian Cysts Within 2 Months
Monday, March 2, 2020
Sunday, March 1, 2020
Phytochemical Tocopherols, the Renal Protective Antioxidants
The kidneys are a pair of kidney-shaped organs located on either side of your spine with a function to filter out the wastes from the blood before passing the wastes through urinary secretion.
More than a detoxed organ, the kidneys also maintain the body fluid balance, regulate the production of red blood cells and high blood pressure.
Kidney damage can be acute such as an overdose of toxin or chronic. Acute kidney diseases can be cured if the underlying cause is found.
Chronic kidney disease (CKD) is a slow and progressive disease that can lead to kidney failure over time.
At the advanced of CKD can cause the dangerous levels of fluid, electrolytes and wastes build up in the body.
Renal protection is a strategy that protects the kidney against injury or damage. In other words, renal protection is a process that maintains the function of the kidneys.
Depending on the severity of renal damage, patients may experience symptoms of decreased urine output, fluid retention, that lead to swelling in the legs, ankles or feet, fatigue, nausea, and physical weakness
In severe cases, patients may also have symptoms of shortness of breath, confusion, and irregular heartbeat.
The worse cases of kidney damage can lead to renal failure, a condition that induces wastes and toxins accumulated in the blood. In this stage, dialysis and kidney transplant are the only options.
According to statistics, approximately 14 percent of the US general population suffer from CKD. Believe it or not, more than 661,000 Americans have kidney failure. Of these, 468,000 individuals are on dialysis, and roughly 193,000 live with a functioning kidney transplant.
Tocopherols are phytochemicals of which many have vitamin E activity, belonging to the group of Lipids, found abundantly in butter, egg yolk, milk fat, some vegetable, and seed or nut oils, etc.
On finding a potential phytochemical for the treatment of kidney diseases, researchers examined the pretreatment effect of alpha-tocopherol against oxidative renal tubular damage and subsequent carcinogenesis by ferric nitrilotriacetate (Fe-NTA) in rats.
According to the tested analysis, injection of Fe-NTA in rats fed a standard diet showed an increase of renal mRNA levels of calnexin significantly in 3 hours of treatment-associated with the progression of chronic kidney disease (CKD) to end-stage renal disease.
After the injection of alpha-tocopherol, the levels of renal calnexin mRNA levels were decreased, without altering the protein levels.
In LLC-PK1 cells, the addition of alpha-tocopherol showed strong protective activity against oxidative stress induced by H2O2.
Furthermore, alpha-tocopherol induced N-acetylglucosaminyltransferase 3 involved in kidney cancer suppression.in the tested mice.
Moreover, alpha-tocopherol modifies glycoprotein metabolism partially induced cancer and inflammation by conferring mild ER stress in the protection against kidney cell damage.
Taken altogether, tocopherols may be considered a functional supplement for the prevention and treatment of kidney damage, pending to the confirmation of the larger sample size and multicenter human study.
Intake of tocopherols in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Alpha-tocopherol induces calnexin in renal tubular cells: another protective mechanism against free radical-induced cellular damage by Lee WH1, Akatsuka S, Shirase T, Dutta KK, Jiang L, Liu YT, Onuki J, Yamada Y, Okawa K, Wada Y, Watanabe A, Kohro T, Noguchi N, Toyokuni S. (PubMed)
More than a detoxed organ, the kidneys also maintain the body fluid balance, regulate the production of red blood cells and high blood pressure.
Kidney damage can be acute such as an overdose of toxin or chronic. Acute kidney diseases can be cured if the underlying cause is found.
Chronic kidney disease (CKD) is a slow and progressive disease that can lead to kidney failure over time.
At the advanced of CKD can cause the dangerous levels of fluid, electrolytes and wastes build up in the body.
Renal protection is a strategy that protects the kidney against injury or damage. In other words, renal protection is a process that maintains the function of the kidneys.
Depending on the severity of renal damage, patients may experience symptoms of decreased urine output, fluid retention, that lead to swelling in the legs, ankles or feet, fatigue, nausea, and physical weakness
In severe cases, patients may also have symptoms of shortness of breath, confusion, and irregular heartbeat.
The worse cases of kidney damage can lead to renal failure, a condition that induces wastes and toxins accumulated in the blood. In this stage, dialysis and kidney transplant are the only options.
According to statistics, approximately 14 percent of the US general population suffer from CKD. Believe it or not, more than 661,000 Americans have kidney failure. Of these, 468,000 individuals are on dialysis, and roughly 193,000 live with a functioning kidney transplant.
Tocopherols are phytochemicals of which many have vitamin E activity, belonging to the group of Lipids, found abundantly in butter, egg yolk, milk fat, some vegetable, and seed or nut oils, etc.
On finding a potential phytochemical for the treatment of kidney diseases, researchers examined the pretreatment effect of alpha-tocopherol against oxidative renal tubular damage and subsequent carcinogenesis by ferric nitrilotriacetate (Fe-NTA) in rats.
According to the tested analysis, injection of Fe-NTA in rats fed a standard diet showed an increase of renal mRNA levels of calnexin significantly in 3 hours of treatment-associated with the progression of chronic kidney disease (CKD) to end-stage renal disease.
After the injection of alpha-tocopherol, the levels of renal calnexin mRNA levels were decreased, without altering the protein levels.
In LLC-PK1 cells, the addition of alpha-tocopherol showed strong protective activity against oxidative stress induced by H2O2.
Furthermore, alpha-tocopherol induced N-acetylglucosaminyltransferase 3 involved in kidney cancer suppression.in the tested mice.
Moreover, alpha-tocopherol modifies glycoprotein metabolism partially induced cancer and inflammation by conferring mild ER stress in the protection against kidney cell damage.
Taken altogether, tocopherols may be considered a functional supplement for the prevention and treatment of kidney damage, pending to the confirmation of the larger sample size and multicenter human study.
Intake of tocopherols in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Alpha-tocopherol induces calnexin in renal tubular cells: another protective mechanism against free radical-induced cellular damage by Lee WH1, Akatsuka S, Shirase T, Dutta KK, Jiang L, Liu YT, Onuki J, Yamada Y, Okawa K, Wada Y, Watanabe A, Kohro T, Noguchi N, Toyokuni S. (PubMed)
Potatoes May Protect the Liver Cells Against the Development of Fibrosis, Researchers Say
Fibrosis is a condition characterized by overly exuberant wound healing causing excessive connective tissue builds up in the organ tissues In other words, hepatic fibrosis is a portion of the liver which was affected by scars formation.
The exact causes of fibrosis are unknown. However, certain risk factors such as repeated liver injury caused by a virus infection, and a blockage in the bile ducts are found to elaborate on the onset of fibrosis.
The 2 most common types of fibrosis in the human body are
* Renal fibrosis is a progressive condition caused by excessive accumulation of extracellular matrix including collagen, enzymes, and glycoproteins which provided structural and biochemical support of surrounding the renal cells during aging and chronic kidney disease (CKD).
According to the statistics, CKD and renal fibrosis affect approximately half of the adults age 70 and over and 10% of the world's population.
In other words, renal fibrosis is a direct consequence caused by the inability of the kidney to regenerate after injury, leading to the formation of renal scars that results in a progressive loss of renal function.
Most cases of renal fibrosis ultimately lead to end-stage renal failure and a need for dialysis or kidney transplantation.
* Liver fibrosis is a chronic liver disease due to liver scars overwhelmingly building up in the connective tissue in the liver.
The severe case of hepatic fibrosis can lead to cirrhosis, affecting the liver function in filtering the blood. In the US, over 4.5 million people are affected by liver cirrhosis, leading to the death of 12/100,000 of the population every year.
The most common causes of liver fibrosis are excessive alcohol drinking and infected by the hepatitis virus.
Long-term untreated liver fibrosis can lead to cirrhosis, a condition of the severe scarring of the liver and life-threatening liver disease.
Potato is a genus Solanum, belongs to the family Solanaceae. the root veggie is a good source of protein.
According to the statistic, the annual diet of an average global citizen is about 33 kg (72.6 Lbs) of potato. Potato now is growing worldwide in a suitable climate for commercial profits and health benefits, thus its consumption is extremely variable and rapidly changing.
On finding a potential plant that processes anti-fibrotic activity researchers examined the effect of APPH, a potato protein hydrolysate on a high-fat diet (HFD) associated liver damages.
The study included six-week-old male hamsters that were randomly separated to six groups (n = 8) as control, HFD (HFD fed obese), L-APPH (HFD + 15 mg/kg/day of APPH), M-APPH (HFD + 30 mg/kg/day), H-APPH (HFD + 75 mg/kg/day of APPH) and PB (HFD + 500 mg/kg/day of probucol) with HFD fed hamsters were administered with APPH 50 days through oral gavage.
According to the results of the analysis,* Hamsters fed with a high-fat diet showed symptoms of liver damage as measured from serum stress markers like alanine aminotransferase and aspartate aminotransferase levels.
* Furthermore, HFD also modulated the expression of survival and apoptosis proteins in the hamster liver.
* Moreover, the HFD groups showed elevated levels of fibrosis markers in the liver correlated with the increase in the levels of phosphorylated extracellular signal-regulated kinases (pERK1/2) induced liver cell differentiation in the HFD mediated liver damage.
* The administration of a 50-day long supplementation of APPH effectively ameliorated the effects of HFD.
* APPH treatment reduced the effect of HFD on the apoptosis and fibrosis markers considerably and provided hepato-protection.
Collectively, researchers said, "APPH can, therefore, be considered as an efficient therapeutic agent to ameliorate high-fat diet-related liver damages".
Taken altogether, potato may be considered a functional food for the prevention and treatment of liver fibrosis and damage induced fibrosis, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Protein hydrolysate from potato confers hepatic-protection in hamsters against high fat diet induced apoptosis and fibrosis by suppressing Caspase-3 and MMP2/9 and by enhancing Akt-survival pathway by Asokan SM1,2, Hung TH3, Li ZY3, Chiang WD4, Lin WT. (PubMed)
The exact causes of fibrosis are unknown. However, certain risk factors such as repeated liver injury caused by a virus infection, and a blockage in the bile ducts are found to elaborate on the onset of fibrosis.
The 2 most common types of fibrosis in the human body are
* Renal fibrosis is a progressive condition caused by excessive accumulation of extracellular matrix including collagen, enzymes, and glycoproteins which provided structural and biochemical support of surrounding the renal cells during aging and chronic kidney disease (CKD).
According to the statistics, CKD and renal fibrosis affect approximately half of the adults age 70 and over and 10% of the world's population.
In other words, renal fibrosis is a direct consequence caused by the inability of the kidney to regenerate after injury, leading to the formation of renal scars that results in a progressive loss of renal function.
Most cases of renal fibrosis ultimately lead to end-stage renal failure and a need for dialysis or kidney transplantation.
* Liver fibrosis is a chronic liver disease due to liver scars overwhelmingly building up in the connective tissue in the liver.
The severe case of hepatic fibrosis can lead to cirrhosis, affecting the liver function in filtering the blood. In the US, over 4.5 million people are affected by liver cirrhosis, leading to the death of 12/100,000 of the population every year.
The most common causes of liver fibrosis are excessive alcohol drinking and infected by the hepatitis virus.
Long-term untreated liver fibrosis can lead to cirrhosis, a condition of the severe scarring of the liver and life-threatening liver disease.
Potato is a genus Solanum, belongs to the family Solanaceae. the root veggie is a good source of protein.
According to the statistic, the annual diet of an average global citizen is about 33 kg (72.6 Lbs) of potato. Potato now is growing worldwide in a suitable climate for commercial profits and health benefits, thus its consumption is extremely variable and rapidly changing.
On finding a potential plant that processes anti-fibrotic activity researchers examined the effect of APPH, a potato protein hydrolysate on a high-fat diet (HFD) associated liver damages.
The study included six-week-old male hamsters that were randomly separated to six groups (n = 8) as control, HFD (HFD fed obese), L-APPH (HFD + 15 mg/kg/day of APPH), M-APPH (HFD + 30 mg/kg/day), H-APPH (HFD + 75 mg/kg/day of APPH) and PB (HFD + 500 mg/kg/day of probucol) with HFD fed hamsters were administered with APPH 50 days through oral gavage.
According to the results of the analysis,* Hamsters fed with a high-fat diet showed symptoms of liver damage as measured from serum stress markers like alanine aminotransferase and aspartate aminotransferase levels.
* Furthermore, HFD also modulated the expression of survival and apoptosis proteins in the hamster liver.
* Moreover, the HFD groups showed elevated levels of fibrosis markers in the liver correlated with the increase in the levels of phosphorylated extracellular signal-regulated kinases (pERK1/2) induced liver cell differentiation in the HFD mediated liver damage.
* The administration of a 50-day long supplementation of APPH effectively ameliorated the effects of HFD.
* APPH treatment reduced the effect of HFD on the apoptosis and fibrosis markers considerably and provided hepato-protection.
Collectively, researchers said, "APPH can, therefore, be considered as an efficient therapeutic agent to ameliorate high-fat diet-related liver damages".
Taken altogether, potato may be considered a functional food for the prevention and treatment of liver fibrosis and damage induced fibrosis, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Protein hydrolysate from potato confers hepatic-protection in hamsters against high fat diet induced apoptosis and fibrosis by suppressing Caspase-3 and MMP2/9 and by enhancing Akt-survival pathway by Asokan SM1,2, Hung TH3, Li ZY3, Chiang WD4, Lin WT. (PubMed)
Saturday, February 29, 2020
Phytochemical Tocopherols Promotes Bone Collagen Formation Against Osteoporosis
Osteoporosis is a condition associated with low bone mass and deterioration of bone tissue.
The disease is most common in older adults as the result of the bone made by the body can not cover the bone loss due to an increased serum of osteoclast mediator involved in bone resorption.
Consequently, the bone in osteoporotic patients become weak and breaking easily from a fall.
Believe it or not, in serious cases, bone can also be broken due to sneezings or minor bumps.
According to the statistics provided by the International Osteoporosis Foundation, approximately 44 million U.S. women and men aged 50 and older suffer from osteoporosis and low bone mass.
There are over 200 million women worldwide affected by osteoporosis, including one-tenth of women aged 60, one-fifth of women aged 70, two-fifths of women aged 80 and two-thirds of women aged 90.
Mature bone is composed of proteins and 60% of the weight of the bone is mineral, minerals. Approximately 60% of the weight of the bone is mineral, mainly calcium and phosphate. ... and 90% of collagen/
The function of bone collagen only provides strength and structure but holds the bone together to make the bone stronger.
Dr. Daniel König, the lead scientist in examing bone collagen formation in the risk of osteoporosis, wrote, " the intake of SCP increased BMD in postmenopausal women with a primary, age-related reduction of BMD. In addition, SCP supplementation was associated with a favorable shift in bone markers, indicating increased bone formation and reduced bone degradation".
In other words, the intake of specific collagen supplements may increase collagen's bioavailability and reduce the risk of osteoporosis.
Tocopherols are phytochemicals of which many have vitamin E activity, belonging to the group of Lipids, found abundantly in butter, egg yolk, milk fat, some vegetable, and seed or nut oils, etc.
On finding a potential phytochemical for the treatment of osteoporosis, researchers examined the effect of Tocotrienol-Rich Fraction (TRF), the δ-T3 rich oil extracted from Annatto on bone collagen formation.
According to the analysis, the δ-T3 rich oil extracted from Annatto was the most effective and significantly increased LOX expression which is required for the formation of bone collagen cross-links.
Furthermore, TRF treatment decreased the expression of de-novomethyltransferases (DNMTs), DNMT3A and DNMT3B in the induction of bone loss.
Moreover, TRF significantly inhibited JAK2 activation and decreased expression of Fli1, a transcription factor of DNMTs in the induction of impaired osteoclastogenesis against the promotion of osteoblast differentiation in the formation of bone.
Taken altogether, tocopherols may be considered a supplement or improvement of bone collagen formation against the risk of osteoporosis, pending to the confirmation of the larger sample size and multicenter human study.
Intake of tocopherols in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Tocotrienol-rich fraction from annatto ameliorates expression of lysyl oxidase in human osteoblastic MG-63 cells by Kohno K1, Yamada W2, Ishitsuka A2, Sekine M2, Virgona N2, Ota M1,2, Yano T. (PubMed)
(2) Specific Collagen Peptides Improve Bone Mineral Density and Bone Markers in Postmenopausal Women—A Randomized Controlled Study by Daniel König,1,* Steffen Oesser,2 Stephan Scharla,3 Denise Zdzieblik,1 and Albert Gollhofer. (PMC)
The disease is most common in older adults as the result of the bone made by the body can not cover the bone loss due to an increased serum of osteoclast mediator involved in bone resorption.
Consequently, the bone in osteoporotic patients become weak and breaking easily from a fall.
Believe it or not, in serious cases, bone can also be broken due to sneezings or minor bumps.
According to the statistics provided by the International Osteoporosis Foundation, approximately 44 million U.S. women and men aged 50 and older suffer from osteoporosis and low bone mass.
There are over 200 million women worldwide affected by osteoporosis, including one-tenth of women aged 60, one-fifth of women aged 70, two-fifths of women aged 80 and two-thirds of women aged 90.
Mature bone is composed of proteins and 60% of the weight of the bone is mineral, minerals. Approximately 60% of the weight of the bone is mineral, mainly calcium and phosphate. ... and 90% of collagen/
The function of bone collagen only provides strength and structure but holds the bone together to make the bone stronger.
Dr. Daniel König, the lead scientist in examing bone collagen formation in the risk of osteoporosis, wrote, " the intake of SCP increased BMD in postmenopausal women with a primary, age-related reduction of BMD. In addition, SCP supplementation was associated with a favorable shift in bone markers, indicating increased bone formation and reduced bone degradation".
In other words, the intake of specific collagen supplements may increase collagen's bioavailability and reduce the risk of osteoporosis.
Tocopherols are phytochemicals of which many have vitamin E activity, belonging to the group of Lipids, found abundantly in butter, egg yolk, milk fat, some vegetable, and seed or nut oils, etc.
On finding a potential phytochemical for the treatment of osteoporosis, researchers examined the effect of Tocotrienol-Rich Fraction (TRF), the δ-T3 rich oil extracted from Annatto on bone collagen formation.
According to the analysis, the δ-T3 rich oil extracted from Annatto was the most effective and significantly increased LOX expression which is required for the formation of bone collagen cross-links.
Furthermore, TRF treatment decreased the expression of de-novomethyltransferases (DNMTs), DNMT3A and DNMT3B in the induction of bone loss.
Moreover, TRF significantly inhibited JAK2 activation and decreased expression of Fli1, a transcription factor of DNMTs in the induction of impaired osteoclastogenesis against the promotion of osteoblast differentiation in the formation of bone.
Taken altogether, tocopherols may be considered a supplement or improvement of bone collagen formation against the risk of osteoporosis, pending to the confirmation of the larger sample size and multicenter human study.
Intake of tocopherols in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Tocotrienol-rich fraction from annatto ameliorates expression of lysyl oxidase in human osteoblastic MG-63 cells by Kohno K1, Yamada W2, Ishitsuka A2, Sekine M2, Virgona N2, Ota M1,2, Yano T. (PubMed)
(2) Specific Collagen Peptides Improve Bone Mineral Density and Bone Markers in Postmenopausal Women—A Randomized Controlled Study by Daniel König,1,* Steffen Oesser,2 Stephan Scharla,3 Denise Zdzieblik,1 and Albert Gollhofer. (PMC)
Herbal Angelica sinensis, the Potential Anti-Oxidative Stress Remedy
The expression of oxidative stress is a medical condition characterized by the imbalance of the ratio of free radicals and antioxidant enzymes produced by the host tissue.
In some cases, this reaction also is caused long-term accumulation of toxic substances in the body, such as lead, cadmium, mercury, and arsenic.
There is no single cause of oxidative stress. Some researchers suggested that a number of factors can facilitate the onset of oxidative stress, including cigarette smoke, oxidative burst from activated macrophages, particularly, the free radicals chain reaction.
Sadly, a prolonged period of oxidative stress presented in the human body can cause oxidative damage to biomolecules, (lipids, proteins, DNA) and the death of healthy cells through cytotoxicity including atherosclerosis, cancer, diabetics, rheumatoid arthritis, post-ischemic perfusion injury, myocardial infarction, cardiovascular diseases, chronic inflammation, and stroke.
Free radicals are highly reactive molecules with an unpaired electron on the outer ring of the atom.
Due to its nature to become stable, free radicals readily to donate or steal an electron from other molecules, leading to the chain of domino's effect that can not be stopped until either the electrons are paired or inhibited by antioxidants.
This chain of reaction is the cause of oxidative stress, a condition is associated with either overexpression of free radicals or depletion of antioxidant enzymes produced by the host organs.
Antioxidants are stable atom that plays a critical role in protecting the body against the attack of free radicals.
In other words, antioxidants inhibited the onset of free radical before they can cause a chain reaction in facilitating the protein, lipid and cell damage.
Apoptosis refers to the death of cells which occurs as a normal and controlled part of an organism's growth or development associated with the limited cycle division.
Anti-apoptotic activity found in the cancer is associated with the proliferation and unlimited cell cycle division for the growth of cancer.
Chemo drugs used for the treatment of cancer can also cause cancer cell death through inducing toxicity. However, the treatment also leads to the death of healthy cells and weakened immune functioning.
Angelica or Dang Qui is a herb of Genus Angelica from the family Apiaceae, indigenous to China.
The herb has been used as a Queen herb in traditional Chinese medicine antispasmodic and vasodilatory agent, and to balance the hormones in women for a normal menstrual cycle and menstruation and strengthen heart, spleen, kidneys, and liver for both men and women, etc. In other words, it is used to treat gynecological ailments, fatigue, mild anemia, and high blood pressure. It has analgesic, anti-inflammatory, etc.
On finding a natural compound for the treatment of malignant tumors, the researchers examined the effects of Angelica Sinensis' polysaccharide (ASP) anti-apoptotic activity.
Based on the experimental differentiation, IN H9c2 cell, treated with hydrogen peroxide (H2O2), A. Sinensis exerted protective effects against oxidative injury through its various active ingredients on the regulation of multiple pathways associated with pro-inflammatory cytokines induced by oxidative stress.
Furthermore, ASP pretreatment significantly decreased H2O2-induced cytotoxicity and apoptosis in H9c2 cells.
Moreover, H2O2-induced oxidative stress observed by the expression of oxidative stress and ER stress markers such as malondialdehyde production and lactic dehydrogenase release was also inhibited by the antioxidant activity of ASP.
Collectively, researchers said, " Conclusions Our findings indicate that ASP, a major water-soluble component of A. Sinensis, exerts protective effects against H2O2-induced injury in H9c2 cells by activating the ATF6 pathway, thus ameliorating ER and oxidative stress".
Taken altogether, Herbal Angelica may be considered a remedy that protects the cell against oxidative stress, pending to larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Polysaccharide from Angelica sinensis protects H9c2 cells against oxidative injury and endoplasmic reticulum stress by activating the ATF6 pathway by Niu X1, Zhang J2, Ling C3, Bai M4,5, Peng Y4,5, Sun S6, Li Y6, Zhang Z. (PubMed)
(2) Apoptosis in cancer: from pathogenesis to treatment by Rebecca SY Wong. (PMC)
In some cases, this reaction also is caused long-term accumulation of toxic substances in the body, such as lead, cadmium, mercury, and arsenic.
There is no single cause of oxidative stress. Some researchers suggested that a number of factors can facilitate the onset of oxidative stress, including cigarette smoke, oxidative burst from activated macrophages, particularly, the free radicals chain reaction.
Sadly, a prolonged period of oxidative stress presented in the human body can cause oxidative damage to biomolecules, (lipids, proteins, DNA) and the death of healthy cells through cytotoxicity including atherosclerosis, cancer, diabetics, rheumatoid arthritis, post-ischemic perfusion injury, myocardial infarction, cardiovascular diseases, chronic inflammation, and stroke.
Free radicals are highly reactive molecules with an unpaired electron on the outer ring of the atom.
Due to its nature to become stable, free radicals readily to donate or steal an electron from other molecules, leading to the chain of domino's effect that can not be stopped until either the electrons are paired or inhibited by antioxidants.
This chain of reaction is the cause of oxidative stress, a condition is associated with either overexpression of free radicals or depletion of antioxidant enzymes produced by the host organs.
Antioxidants are stable atom that plays a critical role in protecting the body against the attack of free radicals.
In other words, antioxidants inhibited the onset of free radical before they can cause a chain reaction in facilitating the protein, lipid and cell damage.
Apoptosis refers to the death of cells which occurs as a normal and controlled part of an organism's growth or development associated with the limited cycle division.
Anti-apoptotic activity found in the cancer is associated with the proliferation and unlimited cell cycle division for the growth of cancer.
Chemo drugs used for the treatment of cancer can also cause cancer cell death through inducing toxicity. However, the treatment also leads to the death of healthy cells and weakened immune functioning.
Angelica or Dang Qui is a herb of Genus Angelica from the family Apiaceae, indigenous to China.
The herb has been used as a Queen herb in traditional Chinese medicine antispasmodic and vasodilatory agent, and to balance the hormones in women for a normal menstrual cycle and menstruation and strengthen heart, spleen, kidneys, and liver for both men and women, etc. In other words, it is used to treat gynecological ailments, fatigue, mild anemia, and high blood pressure. It has analgesic, anti-inflammatory, etc.
On finding a natural compound for the treatment of malignant tumors, the researchers examined the effects of Angelica Sinensis' polysaccharide (ASP) anti-apoptotic activity.
Based on the experimental differentiation, IN H9c2 cell, treated with hydrogen peroxide (H2O2), A. Sinensis exerted protective effects against oxidative injury through its various active ingredients on the regulation of multiple pathways associated with pro-inflammatory cytokines induced by oxidative stress.
Furthermore, ASP pretreatment significantly decreased H2O2-induced cytotoxicity and apoptosis in H9c2 cells.
Moreover, H2O2-induced oxidative stress observed by the expression of oxidative stress and ER stress markers such as malondialdehyde production and lactic dehydrogenase release was also inhibited by the antioxidant activity of ASP.
Collectively, researchers said, " Conclusions Our findings indicate that ASP, a major water-soluble component of A. Sinensis, exerts protective effects against H2O2-induced injury in H9c2 cells by activating the ATF6 pathway, thus ameliorating ER and oxidative stress".
Taken altogether, Herbal Angelica may be considered a remedy that protects the cell against oxidative stress, pending to larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Polysaccharide from Angelica sinensis protects H9c2 cells against oxidative injury and endoplasmic reticulum stress by activating the ATF6 pathway by Niu X1, Zhang J2, Ling C3, Bai M4,5, Peng Y4,5, Sun S6, Li Y6, Zhang Z. (PubMed)
(2) Apoptosis in cancer: from pathogenesis to treatment by Rebecca SY Wong. (PMC)
Friday, February 28, 2020
Beta-Sitosterol May Alleviates the Progression of Fatty Liver
The liver is the largest internal organ found in the human which plays an essential role in filtering the blood from the digestive system before passing them to other parts of the body.
The liver also produces cholesterol, a waxy substance which aids digestion, builds cell membranes and produces vitamin D and steroid hormones.
Liver disease is a class of medical conditions characterized by reducing partly or completely the function of the liver, including liver failure.
A fatty liver is a liver condition associated with the accumulation of excess fat in the liver.
There are two main types of fatty liver disease:
* Nonalcoholic fatty liver disease is a medical condition characterized by fat accumulated in the liver tissue other than excessive consumption of alcohol.
According to the American liver foundation, Nonalcoholic Fatty Liver Disease is one of the most common causes of liver disease and approximately 30% (100 million) individuals in the United States are estimated to have nonalcoholic fatty liver disease.
The causes of Nonalcoholic Fatty Liver Disease are unknown. Also, as of today researchers do not understand why some people are susceptible to liver fat accumulation while others are not.
The disease can be classified into the types of non-inflammatory fatty liver (NAFL) and inflammatory nonalcoholic steatohepatitis (NASH) and acute fatty liver of pregnancy (AFLP), a relatively rare disorder that happens only during pregnancy.
* Alcoholic fatty liver diseases is a condition caused by lifelong heavy alcohol use.
In other words, substances found in the alcohol damage liver cells, promote inflammation and weaken your body's natural defenses. More precisely, the more alcohol that you drink, the more you damage your liver.
Alcoholic fatty liver disease is the earliest stage of alcohol-related liver disease.
Beta-Sitosterol is a phytochemical in the class of Phytosterols, belongings to the group of Lipids, found abundantly in avocados, rice bran, wheat germ, corn oils, fennel, peanuts, soybeans, hawthorn, basil, buckwheat. etc.
On finding a potential phytochemical for the prevention and treatment of liver diseases, researchers elucidated the effects of stigmasterol and β-sitosterol on a high-fat Western diet (HFWD)-induced nonalcoholic fatty liver disease (NAFLD).
According to the results after 33 weeks of treatment* stigmasterol and β-sitosterol were effective in protecting the liver against HFWD-induced NAFLD.
* The parameters that contributed to the onset of NAFLD are triacylglycerols (TGs), phosphatidylcholines, cholesteryl esters, diacylglycerols, and free fatty acids (FFAs).
* The efficacy of stigmasterol and β-sitosterol int he alleviation of NAFLD was mainly associated with decreases in hepatic cholesterol, TGs with polyunsaturated fatty acids, and alterations of free hepatic FFA.
Based on the findings, researchers said, "phytosterols, at a dose comparable to that suggested for humans by the FDA for the reduction of plasma cholesterol levels, are shown to protect against NAFLD in this long-term (33-week) study".
Beta-Sitosterol may be considered a remedy for the prevention and treatment of NAFLD, pending to the confirmation of the larger sample size and multicenter human study.
Intake of beta-Sitosterol in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Effects of Stigmasterol and β-Sitosterol on Nonalcoholic Fatty Liver Disease in a Mouse Model: A Lipidomic Analysis by Feng S1,2,3, Gan L1, Yang CS2, Liu AB2, Lu W4, Shao P1, Dai Z5, Sun P1, Luo Z. (PubMed)
The liver also produces cholesterol, a waxy substance which aids digestion, builds cell membranes and produces vitamin D and steroid hormones.
Liver disease is a class of medical conditions characterized by reducing partly or completely the function of the liver, including liver failure.
A fatty liver is a liver condition associated with the accumulation of excess fat in the liver.
There are two main types of fatty liver disease:
* Nonalcoholic fatty liver disease is a medical condition characterized by fat accumulated in the liver tissue other than excessive consumption of alcohol.
According to the American liver foundation, Nonalcoholic Fatty Liver Disease is one of the most common causes of liver disease and approximately 30% (100 million) individuals in the United States are estimated to have nonalcoholic fatty liver disease.
The causes of Nonalcoholic Fatty Liver Disease are unknown. Also, as of today researchers do not understand why some people are susceptible to liver fat accumulation while others are not.
The disease can be classified into the types of non-inflammatory fatty liver (NAFL) and inflammatory nonalcoholic steatohepatitis (NASH) and acute fatty liver of pregnancy (AFLP), a relatively rare disorder that happens only during pregnancy.
* Alcoholic fatty liver diseases is a condition caused by lifelong heavy alcohol use.
In other words, substances found in the alcohol damage liver cells, promote inflammation and weaken your body's natural defenses. More precisely, the more alcohol that you drink, the more you damage your liver.
Alcoholic fatty liver disease is the earliest stage of alcohol-related liver disease.
Beta-Sitosterol is a phytochemical in the class of Phytosterols, belongings to the group of Lipids, found abundantly in avocados, rice bran, wheat germ, corn oils, fennel, peanuts, soybeans, hawthorn, basil, buckwheat. etc.
On finding a potential phytochemical for the prevention and treatment of liver diseases, researchers elucidated the effects of stigmasterol and β-sitosterol on a high-fat Western diet (HFWD)-induced nonalcoholic fatty liver disease (NAFLD).
According to the results after 33 weeks of treatment* stigmasterol and β-sitosterol were effective in protecting the liver against HFWD-induced NAFLD.
* The parameters that contributed to the onset of NAFLD are triacylglycerols (TGs), phosphatidylcholines, cholesteryl esters, diacylglycerols, and free fatty acids (FFAs).
* The efficacy of stigmasterol and β-sitosterol int he alleviation of NAFLD was mainly associated with decreases in hepatic cholesterol, TGs with polyunsaturated fatty acids, and alterations of free hepatic FFA.
Based on the findings, researchers said, "phytosterols, at a dose comparable to that suggested for humans by the FDA for the reduction of plasma cholesterol levels, are shown to protect against NAFLD in this long-term (33-week) study".
Beta-Sitosterol may be considered a remedy for the prevention and treatment of NAFLD, pending to the confirmation of the larger sample size and multicenter human study.
Intake of beta-Sitosterol in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Effects of Stigmasterol and β-Sitosterol on Nonalcoholic Fatty Liver Disease in a Mouse Model: A Lipidomic Analysis by Feng S1,2,3, Gan L1, Yang CS2, Liu AB2, Lu W4, Shao P1, Dai Z5, Sun P1, Luo Z. (PubMed)
Green Peas (Pisum Sativum) Inhibits the Risk of Atherosclerosis induced Heart Diseases
Atherosclerosis is a medical condition caused by plaques accumulated on the wall of the arteries, leading to narrowing the arteries in transporting oxygenated blood to the heart and other parts of the body.
Depending on the location of blood obstruction, atherosclerosis can induce different types of heart disease and stroke.
Plaque is the make of cholesterols, calcium, and other toxic substances, including cadmium.
According to the statistics provided by Atherosclerosis Open Acess, 32% of deaths account for atherosclerosis. 13.8% prevalence is among adults of 20 years and above. In 2010, coronary heart disease mortality rate was about 60%.
Atherosclerosis is a slow, progressive disease that may begin as early as childhood, caused by damage to the inner lining of the artery. However, the actual causes of the condition are debatable.
Long term high blood pressure, high cholesterol and triglycerides (a type of fat) in the blood. Particularly, in high levels of insulin in the blood from diabetes and in exposure to chemicals from smoking tobacco.
Patients with early stages of atherosclerosis may not experience any symptoms. However, as the disease progress, patients may have the symptoms of chest pain if the blockage occurs in an artery of the heart (coronary artery) and leg cramps during exercise or walking if the blockage occurs in the legs.
In the advanced stage, if atherosclerosis can lead to a heart attack and stroke, respectively.
Green peas are species of Pisum Sativum belongings to the family Fabaceae and native to western Asia from the Mediterranean Sea to the Himalaya Mountains. The pea is a green, pod-shaped vegetable and a cool-season crop grown in many parts of the world.
On finding a potent ingredient for the treatment of diseases associated with arterial plaques accumulation, researchers investigated the impact of a diet rich in green and yellow vegetables on the development of atherosclerosis.
The study included a mouse model of atherosclerosis, randomized into 2 diet groups: 1) a vegetable-free control diet (n = 53) and 2) the same diet with 30% (w:w) replaced by an equal-parts mixture of freeze-dried peas, green beans, broccoli, corn, and carrots (n = 54), for 16 weeks.
According to the tested analysis,
* Aortic atherosclerosis estimated by cholesteryl ester content, was reduced 38% (P < 0.001) in mice fed the vegetable-rich diet.
* Plasma total cholesterol (-12%), VLDL + ILDL cholesterol (-32%), serum amyloid A (-37%), and body weight (-7%) (all P < 0.01) were also lower in vegetable-rich diet mice at the end of the treatment period. comapred to control.
* In a regression model, a vegetable-rich diet demonstrated antiatherogenic effects of the vegetable diet without explaining the levels of plasma lipoproteins or body weight.
Based on the results, scientists said, " ...a diet rich in green and yellow vegetables inhibits the development of atherosclerosis and may, therefore, lead to a reduction in the risk of coronary heart disease".
Taken altogether, green peas may be considered a functional food for the prevention of atherosclerosis induced heart diseases, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Green Peas (Pisum Sativum) atherosclerosis by Adams MR1, Golden DL, Chen H, Register TC, Gugger ET. (PubMed)
Depending on the location of blood obstruction, atherosclerosis can induce different types of heart disease and stroke.
Plaque is the make of cholesterols, calcium, and other toxic substances, including cadmium.
According to the statistics provided by Atherosclerosis Open Acess, 32% of deaths account for atherosclerosis. 13.8% prevalence is among adults of 20 years and above. In 2010, coronary heart disease mortality rate was about 60%.
Atherosclerosis is a slow, progressive disease that may begin as early as childhood, caused by damage to the inner lining of the artery. However, the actual causes of the condition are debatable.
Long term high blood pressure, high cholesterol and triglycerides (a type of fat) in the blood. Particularly, in high levels of insulin in the blood from diabetes and in exposure to chemicals from smoking tobacco.
Patients with early stages of atherosclerosis may not experience any symptoms. However, as the disease progress, patients may have the symptoms of chest pain if the blockage occurs in an artery of the heart (coronary artery) and leg cramps during exercise or walking if the blockage occurs in the legs.
In the advanced stage, if atherosclerosis can lead to a heart attack and stroke, respectively.
Green peas are species of Pisum Sativum belongings to the family Fabaceae and native to western Asia from the Mediterranean Sea to the Himalaya Mountains. The pea is a green, pod-shaped vegetable and a cool-season crop grown in many parts of the world.
On finding a potent ingredient for the treatment of diseases associated with arterial plaques accumulation, researchers investigated the impact of a diet rich in green and yellow vegetables on the development of atherosclerosis.
The study included a mouse model of atherosclerosis, randomized into 2 diet groups: 1) a vegetable-free control diet (n = 53) and 2) the same diet with 30% (w:w) replaced by an equal-parts mixture of freeze-dried peas, green beans, broccoli, corn, and carrots (n = 54), for 16 weeks.
According to the tested analysis,
* Aortic atherosclerosis estimated by cholesteryl ester content, was reduced 38% (P < 0.001) in mice fed the vegetable-rich diet.
* Plasma total cholesterol (-12%), VLDL + ILDL cholesterol (-32%), serum amyloid A (-37%), and body weight (-7%) (all P < 0.01) were also lower in vegetable-rich diet mice at the end of the treatment period. comapred to control.
* In a regression model, a vegetable-rich diet demonstrated antiatherogenic effects of the vegetable diet without explaining the levels of plasma lipoproteins or body weight.
Based on the results, scientists said, " ...a diet rich in green and yellow vegetables inhibits the development of atherosclerosis and may, therefore, lead to a reduction in the risk of coronary heart disease".
Taken altogether, green peas may be considered a functional food for the prevention of atherosclerosis induced heart diseases, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Green Peas (Pisum Sativum) atherosclerosis by Adams MR1, Golden DL, Chen H, Register TC, Gugger ET. (PubMed)
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