Socrates Said," Let foods be your medicine and let medicine be your foods". Let us all practice the values of the past wisdom to build a letter living and living health while we enjoy the delicious drinks

Ovarian Cyst Miracle (tm)

Ovarian Cyst Miracle (tm)
Permanently and Naturally, Eliminate All Types of Ovarian Cysts Within 2 Months

Friday, February 26, 2016

The Curable Smoothie of Green Tea, Cranberry and Carrot for Reduced Risk and Treatment of Pharynx (Throat) Cancer

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for reduced risk and treatment of Pharynx (Throat) Cancer
Yield: 2 servings (about 8 ounces each)
1 gram of formula RRF(you cam buy them in any Chinese herbal store)
1 1/4 cup cranberry
1/4 cup of carrot
1 cup green tea drink (Make from 4 grams of green tea, a slice of ginger and a cup of hot water lipped for 5 minutes, and let cool to room temperature)

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately

The finding the natural ingredients for reduced symptoms and treatment of Perimenopause is considered as a dream of many scientist to replace the long usage adverse effect of conventional medicine.
Unfortunately, many compounds found effective in initial studying failed to confirm the potentials in large sample size and multi center.

Recent studies suggested that scientist in some research centers have found the naturally potential ingredients of green tea(1), Cranberry(5 )and Carrot(8)  for reduced risk and treatment of Pharynx (Throat) Cancer.

Pharynx cvancer is the irregual cell growth in the curve area of the back of the mouth, located between esophagus and trachea connecting the nasal and oral cavities to the larynx. In the United States in 2010 alone, according to National cancer Institute, there were 12,660 new cases of pharyngeal cancer, resulting in deaths of 2,410 patients.

Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Because of their health benefits, they have been cultivated for commercial purposes all over the world. According to Dr, Tian M and colleagues, green tea polyphenol significantly inhibited cell proliferation, induced cell apoptosis and decreased the migration and invasion ability of NPC cells in vitro(1).
In the study of nasopharyngeal carcinoma(NPC) cells HONE1 and CNE2, green tea also expressed anti proliferation activity through suppression of the growth of xenografts(2).

In the review of literature from data bases before January 2014 in MEDLINE and EMBASE, tea intake is associated to decrease risk of Pharynx Cancer with no evidence of publication bias.according to the Begg's funnel plot and the Egger's test(3).The National Yang-Ming University study suggested, epigallocathechin gallate (EGCG), the major polyphenol in green tea inhibited sphere formation, eliminated the stem-like properties against nasopharyngeal carcinoma (NPC) through attenuaAT3 activation of cellular processes such as cell growth and apoptosis(4).

Cranberry is a species of Vaccinium oxycoccos, belong to the family Ericaceae found in the cooler part of Northern America. According to the Medical College of Wisconsin, phytochemicals found in cranberry inhibited esophageal adenocarcinoma in vitro assay and in vivo models(5).
Resveratrol, another major constituent found in cransberry, also inhibited proliferation and induced apoptosis of nasopharyngeal carcinoma cell line C666-1 through AMPK activation of cellular energy homeostasis(6) and activate caspase-3 in cell death and alter the Bax/Bcl-2 apoptotic signaling(6).

In nude mice, resveratrol induced more sensitive of on human hypopharyngeal carcinoma to radiation therapy(7). Combination of radiotherapy plus resveratrol treatment resulted in a tumor inhibition rate of 76.64%, according to the joint study lead by the First Affiliated of Xi'an Jiao Tong University(7).

Retinoic acid, a metabolite of vitamin A (retinol) found in a measure amount in carrot may also be a potential ingredient in prevention and treatment of Pharynx Cancer. According to the Hunan Cancer Hospital and The Affiliated Cancer Hospital of Xiangya School of Medicine, all-trans-retinoic acid-induced growth inhibition and differentiation in nasopharyngeal cancercells through suppression nasopharyngeal carcinoma (NPC) tumor formation by Human SPLUNC1 in expression in the upper airways and nasopharyngeal regions(8). In fact, plasma antioxidant vitamins like vitamin A were lower in oral cavity and oropharyngeal cancer patients than healthy controls, Dr. Marakala V and colleagues said(9).Use conjunction with cisplatin, all-trans retinoid acid (ATRA), the combination significantly inhibited the growth of both cell lines of (NPC-TW01 and NPC-TW04)(10).

The combination of Green Tea, Cranberry and Carrot smoothie may hold a key in further studies in production of an effective natural ingredients for prevention and treatment of Pharynx Cancer without inducing adverse effects.

People who are at higher risk of Pharynx Cancer due to family history,.......should take at least one serving daily. People with Pharynx Cancer should drink as much as they can depending to the digestive toleration.


All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/p/general-health.html

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca






References
(1) [Tumor suppressive effect and relative mechanisms of tea polyphenol on nasopharyngeal carcinoma cells].[Article in Chinese] by Tian M, Yuan D, Zheng S, Li Q, Shi S, Xu Z.(PubMed)
(2) [The effects of tea polyphenols and Laminaria japonica polysaccharides on nasopharyngeal carcinoma cell HONE1 and CNE2].[Article in Chinese]by Sun W1, Wei Y, Zeng M, Zheng S, Xu Z.(PubMed)
(3) Tea intake and risk of oral, pharyngeal, and laryngeal carcinoma: a meta-analysis by Zhang W1, Geng T2, Han W1, Dou H3.(PubMed)
(4) EGCG inhibits the growth and tumorigenicity of nasopharyngeal tumor-initiating cells through attenuation of STAT3 activation by Lin CH1, Chao LK2, Hung PH3, Chen YJ4.(PubMed)
(5) Upper esophageal and pharyngeal cancers by Bock JM1, Howell AB, Johnston N, Kresty LA, Lew D.(PubMed)
(6) Resveratrol inhibits proliferation and induces apoptosis of nasopharyngeal carcinoma cell line C666-1 through AMPK activation by Cai Y, Zhao L, Qin Y, Zhang M, He Y.(PubMed)
(7) [Resveratrol enhances radiosensitivity of human hypopharyngeal carcinoma cell line in nude mice].[Article in Chinese] by Quan F1, Zhao Q, Shao Y, Li H, Zhao R.(PubMed)
(8) SPLUNC1 is associated with nasopharyngeal carcinoma prognosis and plays an important role in all-trans-retinoic acid-induced growth inhibition and differentiation in nasopharyngeal cancercells by Zhang W1, Zeng Z, Wei F, Chen P, Schmitt DC, Fan S, Guo X, Liang F, Shi L, Liu Z, Zhang Z, Xiang B, Zhou M, Huang D, Tang K, Li X,Xiong W, Tan M, Li G, Li X.(PubMed)
(9) Lipid peroxidation and antioxidant vitamin status in oral cavity and oropharyngeal cancerpatients. by Marakala V1, Malathi M, Shivashankara AR.(PubMed)
(10) Effect of all-trans retinoic acid on the growth of two nasopharyngeal cancer cell lines and its treatment potential in combination with cisplatin. by Hung SH1, Lee FP, Su CH, Tseng H.(PubMed)

The Curable Smoothie of Green Tea, Blueberry and Strawberry for reduced Risk and Treatment of Mouth (Oral) cancer



Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


The smoothie for reduced risk and treatment of Oral cancer

Yield: 2 serving (about 8 ounce each)
3/4 cup blueberry
3/4 cup strawberry
1 cup green tea drink (Make from 4 grams of green tea, a slice of ginger and a cup of hot water lipped for 5 minutes, and let cool to room temperature)

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately

The finding the natural ingredients for treatment of Mouth (Oral) cancer is considered as a dream of many scientist to replace the long term usage adverse effect of conventional medicine. Unfortunately, many compounds found effective in initial studying failed to confirm the potential in large sample size and multi center.

Oral cancer is any malignant cell growth in the tissue located in the oral cavity, including the tissue of the lips or the tongue, cheek lining, floor of the mouth, gums (gingiva) and the roof of the mouth (palate).

Recent studies conducted by some renowned institutions, expressed the interest of formula containing green tea, blueberry and strawberry in reduced risk and treatment of oral cancer.

Green tea contains more amount of antioxidants than any drinks or food with the same volume, and is the leaves of Camellia sinensis, undergone minimal oxidation during processing, originated from China. Its phytochemicals have been found to process anti cancer effects through different mechanisms. Epigallocatechin-3-gallate, a major bioactive component of green tea, suppressed SSC-4 human oral squamous cell carcinoma (OSCC) cell line proliferation, through activation of apoptosis and autophagy(2) and depending on the differential prooxidant effects in cancer and normal cells(4).

According of he Fujian Medical University,said, "Tea consumption, age of tea drinking initiation, duration of tea consumption, average daily tea consumed, concentration of teaconsumed, types of tea and temperature of tea might have impact on the incidence of oral cancer"(1).

Dr. Zhang W and the colleagues at the Qilu Hospital of Shandong University in the review of literature conducted before January 2014 in MEDLINE and EMBASE databases suggested, tea consumption was associated with decreased risk of oral cancer(3).

Polyphenols found abundantly in blue berry, which is a flower plant, belongings to the family Eriaceae, native to Northern America, is a phytochemical in the class of Stilbenoids also exhibited anti oral cancer effects through suppressed the proliferation and induced G2/M cell cycle arrest and apoptosis of oral cancer KB cells in dose-depend manner(5).

Dr. Iriti M and Dr. Varoni EM. said, " the chemopreventive potential of flavonoids and flavonoid-rich foods, (including blue barry) in human oral carcinogenesis" base on "data from clinical trials and epidemiological studies, in comparison to in vitro/in vivo investigations"(6).

Strawberries is a genius of Fragaria × ananassa belongs to the family Roseaceae. They have been grown all over the world with suitable climate for commercial profits and for health benefits. According to the The Ohio State University, the fruits can inhibit tumor formation in an animal model of oral cancer(7).Dr. Seeram NP and colleagues at the University of California in the study of the effects of berries against cancers found that, berry, including strawberry phenolics anthocyanins, flavonols, flavanols, ellagitannins, gallotannins, proanthocyanidins, and phenolic acids, ameliorated the growth of human oral (KB, CAL-27), with a significant pro-apoptotic effects(8).

The combination of Green Tea, Blueberry and Strawberry smoothie may hold a key in further studies in production of an effective natural ingredients for prevention and treatment of Mouth (Oral) cancer without inducing adverse effects.

People who are at higher risk of mouth (oral) cancer due to family history,.......should take at least one serving daily. People with mouth (oral) cancer should drink as much as they can depending to the digestive toleration.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/p/general-health.html

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

References
(1) [Effect of tea on oral cancer in nonsmokers and nondrinkers: a case-control study].[Article in Chinese] by Chen F1, He B2, Huang J, Liu F, Yan L, Hu Z, Lin L, He F.(PubMed)
(2) Epigallocatechin-3-gallate suppresses cell proliferation and promotes apoptosis and autophagy in oral cancerSSC-4 cells by Irimie AI1, Braicu C2, Zanoaga O2, Pileczki V3, Gherman C4, Berindan-Neagoe I5, Campian RS6.(PubMed)
(3) Tea intake and risk of oral, pharyngeal, and laryngeal carcinoma: a meta-analysis by Zhang W1, Geng T2, Han W1, Dou H3.(PubMed)
(4) Differential prooxidative effects of the green tea polyphenol, (-)-epigallocatechin-3-gallate, in normal and oral cancer cells are related to differences in sirtuin 3 signaling by Tao L1, Park JY, Lambert JD.(PubMed)
(5) Blueberry anthocyanins induce G2/M cell cycle arrest and apoptosis of oral cancer KB cells through down-regulation methylation of p53].[Article in Chinese] by Qi C1, Li S1, Jia Y1, Wang L1.(PubMed)
(6) Chemopreventive potential of flavonoids in oral squamous cell carcinoma in human studies. by Iriti M1, Varoni EM.(PubMed)
(7) Chemoprevention of oral cancer by lyophilized strawberries by Casto BC1, Knobloch TJ, Galioto RL, Yu Z, Accurso BT, Warner BM.(PubMed)
(8) Blackberry, black raspberry, blueberry, cranberry, red raspberry, and strawberry extracts inhibit growth and stimulate apoptosis of human cancer cells in vitro by Seeram NP1, Adams LS, Zhang Y, Lee R, Sand D, Scheuller HS, Heber D.(PubMed)

Thursday, February 25, 2016

The Curable Smoothie Green Tea, Grape and Curcumin for Reduced Risk and Treatment of Hidradenitis Suppurativa (HS)

Kyle J. Norton (Scholar, and Master of nutrients) All right reserved
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for reduced risk and treatment of Hidradenitis suppurativa (HS)

Yield: 2 servings (about 8 ounces each)
1 1/2 cups grape
1 tsp curcumin
1 cup green tea drink (Make from 4 grams(2 tea bags) of green tea, a slice of ginger and a cup of hot water lipped for 5 minutes, and set aside for cooling to room temperature)

1. Place the all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately


The dream of finding the natural ingredient for prevention and treatment of Hidradenitis suppurativa (HS) without adverse effects in replacement of conventional medicine has not been abated. Some ingredients have to discard because of not achieving the same potent results in human trials.

Hidradenitis suppurativa (HS) is a condition of skin disease with the development of pimple-like bumps mostly on areas of armpits, groin, inducing long-term skin inflammation and pain.

Recent studies reported by numerous well known institution, green tea, grape and may process anti skin inflammatory diseases properties(1) in reduced risk and treatment of chronic hidradenitis suppurativa (HS) without persuaded adverse effects.

Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Due to its commercial values and health effects, green tea now has been cultivated all over the world in suitable climate.According to the Institute of Information Technology, green tea exerted its therapeutic properties of anti skin infectious effects through inhibition of adhesion at its minimal inhibitory concentration (MIC) value(2).

Dr. Lee JH and colleagues at the Korea University, said, "Green tea extract-4 (CSI-4) exert a selective anti-adhesive effect against certain pathogenic bacteria with no adverse effects against beneficial or commensal bacteria."(3).

Resveratrol, a phytochemical in the class of Stilbenoids, found abundantly in grape also displays antioxidant, anti-inflammatory, antimicrobial activities in reduced risk and treatment of skin diseases(4).

In skin inflammatory in mice, resveratrol exerted strongly anti-inflammatory effects in various cells, tissues, animals and human settings of low-grade inflammation, through anti proinflammatory patways, su as IL-17A and IL-19(5).
With its anti-inflammation associated with immune responses, resveratrol also attenuated atopic dermatitis (AD) mouse model by modulating the HMGB1 protein expression, in targeting skin inflammation(6).

Turmeric is a perennial plant in the genus Curcuma, belongings to the family Zingiberaceae, native to tropical South Asia used in traditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.

Its major phytochemical constituent curcumin used conjunction with resveratrol were excellent candidates for skin treatment, according to joint study lead by the Saarland University(4).
Dr. Sun J and colleagues at the General Hospital of Jinan Military Command, said, " Curcumin has been confirmed to have anti-inflammatory properties in addition to the ability to decrease the expression of pro-inflammatory cytokines in keratinocytes"(7).Furthermore, according to the, topical administration of curcumin may effectively use for treatment of skin-related disorders. due to its property of directly deliver to the affected tissue(8).

The discovery of combined ingredients of green tea, grape, and turmeric may act as a cornerstone for induction of further investigation of the effectiveness of natural smoothie in reduced risk and treatment of Hidradenitis suppurativa (HS).

People who are at increased risk of Hidradenitis suppurativa (HS) due to family history, aging,... may drink one or 2 servings a day, people with Hidradenitis suppurativa (HS) should drink as much as they can depending to the digestive alternation.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/p/general-health.html

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca


References
(1) A new function of green tea: prevention of lifestyle-related diseases by Sueoka N1, Suganuma M, Sueoka E, Okabe S, Matsuyama S, Imai K, Nakachi K, Fujiki H.(PubMed)
(2) Green tea extract: possible mechanism and antibacterial activity on skin pathogens By Sharma A1, Gupta S, Sarethy IP, Dang S, Gabrani R.(PubMed)
(3) In vitro anti-adhesive activity of green tea extract against pathogen adhesion by Lee JH1, Shim JS, Chung MS, Lim ST, Kim KH.(PubMed
(4) Skin penetration behavior of lipid-core nanocapsules for simultaneous delivery of resveratroland curcumin. by Friedrich RB1, Kann B2, Coradini K1, Offerhaus HL3, Beck RC4, Windbergs M5.(PubMed)
(5) Resveratrol ameliorates imiquimod-induced psoriasis-like skin inflammation in mice. by Kjær TN1, Thorsen K2, Jessen N2, Stenderup K3, Pedersen SB1.(PubMed)
(6) Resveratrol attenuates HMGB1 signaling and inflammation in house dust mite-induced atopic dermatitis in mice. by Karuppagounder V, Arumugam S, Thandavarayan RA, Pitchaimani V, Sreedhar R, Afrin R, Harima M, Suzuki H, Nomoto M, Miyashita S,Suzuki K, Watanabe K.(PubMed)
(7) Curcumin relieves TPA-induced Th1 inflammation in K14-VEGF transgenic mice. by Sun J1, Zhao Y2, Jin H3, Hu J4.(PubMed)

The Curable Green Tea, Grape and Walnut Smoothie for Reduced Risk and Treatment of Keloid

Kyle J. Norton(Scholar, Master of Nutrient, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


The smoothie for reduced risk and treatment of Keloid
Yield: 2 serving (about 8 ounce each)
1 3/4 cup grape
14 cup of walnut
1 cup green tea drink (Make from 4 grams of green tea, a slice of ginger and a cup of hot water lipped for 5 minutes, and let cool to room temperature)


1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately

Keloid is a condition of forming of f irregular fibrous tissue at the site of a scar or injury.

Green tea containing more amount of antioxidants than any drinks or food with the same volume, and is the leaves of Camellia sinensis, undergone minimal oxidation during processing, originated from China. According to the Southwest Jiaotong University, may be effective for treatment of keloid and safety to the skin through its capabilities of maintaining a moist environment, resisting bacterial infection and controlling the drug release when co-delivery with dexamethasone(1).

Other green tea phytochemical, polyphenol epigallocatechin-3-gallate, also processed anti collagen accumulation and hyperproliferation of fibroblasts, through regulation of the cytokines and growth factors of gene Signal transducer and activator of transcription 3(STAT-3)(2)in promoting collagen production, cell proliferation and migration(3).

Dr. Zhang Q and colleagues at the University of Southern California said, " interaction between mast cells (MCs), and keloid fibroblasts may contribute to excessive collagen accumulation in keloids and imply a therapeutic potential of green tea for the intervention and prevention of keloids and other fibrotic diseases"(4).


Grape is a woody vines of the genus Vitis, belongings to the family Vitaceae, native to southern Turkey. Recent study suggested that its antioxidant resveratrol may be the next generation natural food source used for reduced risk and treatment in patients with Keloid(5), through expression of inhibited fibrogenesis and induced apoptosis.

Walnut tree is one of the Genus plant belongings to the family Juglandaceae cultivated for its nut and kernel and for commercial purpose all over the world. Its Omega 3 fatty acids is associated in reducing actively proliferating keloid fibroblasts, according to the Ladoke Akintola University of Technology Teaching Hospital(6).
Dr. Louw L, professor at the University of the Orange Free State said,"...the omega-3 series (a-linolenic acid (ALA) and eicosapentaenoic acid (EPA)) prevent the prevalent in keloid formations through regulation of fibroblast membrane EFAD of arachidonic acid (AA) precursors and inflammatory competitors(7).


The finding of the effectiveness of Green Tea, Grape and Walnut for Protection against formation of Keloid, through theirs phytochemicals may serve as cornerstones of pharmaceutical target for further studies as well as a potential medication for treatment of Keloid.

People who are at high risk of Keloid formation. such as aging, genetic mutation genes,.....should drink at least one cup daily and people with Keloid should drink the juices as much as they can depending to digestive toleration.


All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/p/general-health.html

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca



References
(1) Co-delivery of dexamethasone and green tea polyphenols using electrospun ultrafine fibers for effective treatment of keloid by Li J1, Fu R, Li L, Yang G, Ding S, Zhong Z, Zhou S.(PubMed)
(2) Green tea polyphenol epigallocatechin-3-gallate suppresses collagen production and proliferation in keloidfibroblasts via inhibition of the STAT3-signaling pathway by Park G1, Yoon BS, Moon JH, Kim B, Jun EK, Oh S, Kim H, Song HJ, Noh JY, Oh C, You S.(PubMed)
(3) Stat3 contributes to keloid pathogenesis via promoting collagen production, cell proliferation and migration by Lim CP1, Phan TT, Lim IJ, Cao X.(PubMed)
(4) Green tea extract and (-)-epigallocatechin-3-gallate inhibit mast cell-stimulated type I collagen expression inkeloid fibroblasts via blocking PI-3K/AkT signaling pathways by Zhang Q1, Kelly AP, Wang L, French SW, Tang X, Duong HS, Messadi DV, Le AD.(PubMed)
(5) Resveratrol inhibits fibrogenesis and induces apoptosis in keloid fibroblasts by Ikeda K1, Torigoe T, Matsumoto Y, Fujita T, Sato N, Yotsuyanagi T.(PubMed)
(6) Inhibitory activities of omega-3 Fatty acids and traditional african remedies on keloid fibroblasts by Olaitan PB1, Chen IP2, Norris JE3, Feinn R4, Oluwatosin OM5, Reichenberger EJ2.(PubMed)
(7) Keloids in rural black South Africans. Part 3: a lipid model for the prevention and treatment of keloid formations by Louw L1.(PubMed)

Wednesday, February 24, 2016

The Curable Smoothie of Green Tea, Grape and Tomato for Reduced Risk and Treatment of Larynx (Voice Box) Cancer/Laryngeal Cancer

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


The smoothie for reduced risk and treatment of Larynx (Voice Box) Cancer/Laryngeal Cancer
Yield: 2 serving (about 8 ounce each)

3/4 cup grape
3/4 cup tomato
1 cup green tea drink (Make from 4 grams(2 tea bags) of green tea, a slice of ginger and a cup of hot water lipped for 5 minutes, and set aside for cooling to room temperature)

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately


Back by well known institution, according to the recent studies, green tea(1), may be next potential therapeutic target for producing a curable medication for reduced risk and treatment of larynx (voice box) cancer/laryngeal cancer

Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Due to its commercial values and health effects, green tea now has been cultivated all over the world in suitable climate.

Larynx cancer is also known as cancer of the larynx or laryngeal carcinoma, developed in any part of the larynx. Most larynx cancers are squamous cell carcinomas as a result of uncontrolled multiplication of transformed malignant cells in the laryngeal epithelium originated in the glottis.

According to The Food Technology and Biotechnology, flavonoid constituents of gree tea epigallocatechin gallate (EGCG) and epicatechin gallate (ECG) on human laryngeal carcinoma cell line (HEp2) through exhibition of scavenge free radicals, and induce pro-oxidative reactions in the cell(1).The portion of phytochemical Epigallocatechin-3-gallate (EGCG), inhibited the progression of aryngealsquamous cell carcinoma (LSCC) through induced apoptosis via inhibiting the telomerase activity in stopping the divide indefinitely of cells incancer forming(2) as well as induced apoptosis through cell cycle arrest(3).
Flavonoids found abundantly in grape may also exert the potential effect in preventing and treating Laryngeal Cancer. Dr. Garavello W and the research team at the Istituto di Ricerche Farmacologiche Mario Negri suggested(4).

Resveratrol, another phytochemical found in grape also strongly depress cell growth and inhibit cell proliferation in human Hep-2 cell in a time- and dose-dependent manner(5).

Dr. Li T and colleagues at the Medical School of Xi'an Jiaotong University said, "resveratrol could strengthen anti-tumor immunoresponse, accommodating lymphocyte to secrete cytokine, through which it exerted the efficiency of anti-laryngocarcinoma"(6) and "improved function of T, B lymphocytes, killing activity of NK cells, release of antibodies, and the total complement activity in serum"(7).

Tomato is a red, edible fruit, genus Solanum, belongings to family Solanaceae, native to South America. Because of its health benefits, tomato is grown world wide for commercial purpose
and often in green house. As a diet rich in carotenoids has shown to protect against head and neck cancer(10).

Tomato major chemical constituents, retinol, alpha-tocopherol, and carotenoids
offer protection from oxidative damage and potentiate the immune system against the forming of
cancer of the larynx(8).
According to the Yale University School of Medicine, plasma lycopene was significantly associated (inversely) with total mortality in the full study population with oral, pharynx or larynx cancers(9).

The identification of combined ingredients of green tea(1), grape(4) and tomato(7) may act as a cornerstone for induction of further investigation of the effectiveness of natural smoothie in reduced risk and treatment of laryngeal Cancer
People who are at increased risk of laryngeal Cancer due to family history, gene mutation, obesity.....should drink at least one serving daily and people with laryngeal Cancer should drink no more than 4 serving a day, depending to digestive toleration.
Change of life style and diet pattern are also recommended.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/p/general-health.html





Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca




References
(1) Genotoxic effects of green tea extract on human laryngeal carcinoma cells in vitro by Durgo K1, Kostić S, Gradiški K, Komes D, Osmak M, Franekić J.(PubMed)
(2) Apoptosis induction effects of EGCG in laryngeal squamous cell carcinoma cells through telomerase repression by Wang X1, Hao MW, Dong K, Lin F, Ren JH, Zhang HZ.(PubMed)
(3) EGCG induces apoptosis in human laryngeal epidermoid carcinoma Hep2 cells via mitochondria with the release of apoptosis-inducing factor and endonuclease G. by Lee JH1, Jeong YJ, Lee SW, Kim D, Oh SJ, Lim HS, Oh HK, Kim SH, Kim WJ, Jung JY.(PubMed)
(4) Flavonoids and laryngeal cancer risk in Italy by Garavello W1, Rossi M, McLaughlin JK, Bosetti C, Negri E, Lagiou P, Talamini R, Franceschi S, Parpinel M, Dal Maso L, La Vecchia C.(PubMed)
(5) [Inhibit affection of resveratrol on the growth of Hep-2 cell line].[Article in Chinese] by Li Y1, Xu Y, Huang D, Jiang L, Li K.(PubMed)
(6) [Research of a new kind of biological response modifier to anti-laryngocarcinoma].[Article in Chinese] by Li T1, Fan G, Li T, Yuan Y, Shi L.(PubMed)
(7) [Preliminary study on anti-tumor function of resveratrol and its immunological mechanism].[Article in Chinese] by Li T1, Sheng L, Fan GX, Yuan YK, Li T.(PubMed)
(8) Evaluation of retinol, alpha-tocopherol, and carotenoids in serum of men with cancer of the larynx before and after commercial enteral formula feeding by Olmedilla B1, Granado F, Blanco I, Rojas-Hidalgo E.(PubMed)
(9) Low plasma lycopene concentration is associated with increased mortality in a cohort of patients with prior oral, pharynx or larynx cancers by Mayne ST1, Cartmel B, Lin H, Zheng T, Goodwin WJ Jr.(PubMed)
(10) Carotenoid intake and head and neck cancer: a pooled analysis in the International Head and Neck CancerEpidemiology Consortium by Leoncini E1, Edefonti V, Hashibe M, Parpinel M, Cadoni G, Ferraroni M, Serraino D, Matsuo K, Olshan AF, Zevallos JP, Winn DM, Moysich K, Zhang ZF,Morgenstern H, Levi F, Kelsey K, McClean M, Bosetti C, Schantz S, Yu GP, Boffetta P, Lee YC, Chuang SC, Decarli A, La Vecchia C, Boccia S.(PubMed)

The Curable smoothie of Green Tea, apple and Tomato for reduced Risk and Treatment of Kaposi's sarcoma back by Respectable Institutions

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for reduced risk and Treatment of Kaposi's sarcoma
Yield: 2 serving (about 8 ounce each)
3/4 cup apple
3/4 cup tomato
1 cup green tea drink (Make from 4 grams of green tea, and a cup of hot water lipped for 5 minutes. Set aside for cooling to room temperature)

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately

The finding the natural ingredients for treatment of Kaposi's sarcoma is considered as a dream of many scientist to replace the chemotherapy adverse effect of conventional medicine. Unfortunately, many compounds found effective in initial studying failed to confirm the potential in large sample size and multi center.

Recent studies suggested that scientist in some research centers have found the naturally potential ingredients, such as Green tea(1), Turmeric(3) and Olive(7) for reduced risk and treatment for
Kaposi's sarcoma.

Kaposi's sarcoma is a cancerous tumor of the connective tissue caused by human herpesvirus 8 (HHV8), and is often associated with AIDS, leading to red or purple bumps of abnormal tissue to grow under the skin, in the lining of the mouth, face, torso or limb in a short rime
Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Due to its commercial values and health effects, green tea now has been cultivated all over the world in suitable climate. According to Università dell'Insubria, green tea flavonoid EGCG inhibited inflammatory cells, mostly neutrophils, and inflammation-associated angiogenesis in modulating the early onset and progression of tumor(1).

In KS-IMM and endothelial cell growth, epigallocatechin-3-gallate (EGCG), the most abundant polyphenol found in green tea expressed an chemopreventive effect in KS tumor growth through its anti-angiogenic activity(2).Furthermore, the study by the University of Hokkaido, suggested, the inhibition of angiogenesis of tumor growth on tumor-associated endothelial progenitor cells (EPC) by green tea epigallocatechin-3-gallate (EGCG) may be as a result of downregulating vascular endothelial growth factor-induced mobilization of endothelial progenitor cells (EPC)(3)

Oleanolic acid triterpenoid, is a group of phytochemical found abundantly in Apples also inhibited the angiogenesis in the Matrigel sponge assay and in KS-Imm (an immortalized Kaposi's sarcoma cell line) tumor growth(4).
According to the Multimedica IRCCS, synthetic oleanane triterpenoid, CDDO-methyl ester (CDDO-Me; methyl 2-cyano-3,12-dioxoolean-1,9-dien-28-oate) also suppressed angiogenesis of of Kaposi's sarcoma cells through pro inflammatory nuclear factor-kappaB, cell and DNA-binding proteins signalling(5).

β-Carotene, a phytochemincal in the class of Carotenes, belongings to the group of Carotenoids (tetraterpenoids), found abundantly in tomato also reduced infections and expressed an inhibition of Kaposi sarcoma diffusion(6).

Alitretinoin gel 0.1 %, or 9-cis-retinoic acid, a form of vitamin A, is approved for the treatment of cutaneous lesions of AIDS-associated Kaposi's sarcoma(7). In fact, all -trans retinoic acid (ATRA), an active metabolite of vitamin A under the family retinoid also exhibited strongly anti-tumour therapeutical schemes for the treatment of various tumoral diseases such as Kaposi's sarcoma(8).

The combined epigallocatechin-3-gallate (EGCG), Oleanolic acid triterpenoid and carotenoids found in green tea, apple and tomato respectively may contribute to further investigation of therapeutic natural ingredients for reduced risk and treatment of Kaposi's sarcoma.
People who are at increased risk of Kaposi's sarcoma due to weaken immunity or chronic illness should drink at least one serving daily and people with Kaposi's sarcoma should drink as much as they can, depending to digestive toleration.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/p/general-health.html

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

References
(1) Angiogenesis and cancer prevention: a vision by Noonan DM1, Benelli R, Albini A.(PubMed)
(2) Mechanisms of inhibition of tumor angiogenesis and vascular tumor growth by epigallocatechin-3-gallate by Fassina G1, Venè R, Morini M, Minghelli S, Benelli R, Noonan DM, Albini A.(PubMed)
(3) Inhibitory effects of epigallocatechin-3 gallate, a polyphenol in green tea, on tumor-associated endothelial cells and endothelial progenitor cells by Ohga N1, Hida K, Hida Y, Muraki C, Tsuchiya K, Matsuda K, Ohiro Y, Totsuka Y, Shindoh M.(PubMed)
(4) Anti-angiogenic activity of a novel class of chemopreventive compounds: oleanic acid terpenoids.Sogno I1, Vannini N, Lorusso G, Cammarota R, Noonan DM, Generoso L, Sporn MB, Albini A.(PubMed)

(5) The synthetic oleanane triterpenoid, CDDO-methyl ester, is a potent antiangiogenic agent by Vannini N1, Lorusso G, Cammarota R, Barberis M, Noonan DM, Sporn MB, Albini A(PubMed)
(6) Short communication: possible activity of beta-carotene in patients with the AIDS related complex. A pilot study by Bianchi-Santamaria A1, Fedeli S, Santamaria L.(PubMed)
(7) Alitretinoin: a comprehensive review by Cheng C1, Michaels J, Scheinfeld N.(PubMed)
(8) All trans retinoic acid and cancer by Siddikuzzaman1, Guruvayoorappan C, Berlin Grace VM.(PubMed)

Tuesday, February 23, 2016

The Curable smoothie of Green Tea, Carrot and Almond for reduced Risk and Treatment of Retinitis pigmentosa back by Respectable Institutions

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for reduced risk and Treatment of Retinitis pigmentosa

Yield: 2 servings (about 8 ounces each)
1 cup olive juice or 1 1/2 cups of olive
1 tsp of curcumin
1 cup green tea drink (Make from 4 grams of green tea, and a cup of hot water lipped for 5 minutes. Set aside for cooling to room temperature)

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately

The finding the natural ingredients for treatment of Retinitis pigmentosa is considered as a dream of many scientist to replace the long term usage adverse effect of conventional medicine to other organs in the body. Unfortunately, many compounds found effective in initial studying failed to confirm the potential in large sample size and multi center.

Retinitis pigmentosa is an genetic degenerate eye disease, damaged to the retina of that can lead to severe vision impairment and blindness.
Recent studies suggested that scientist in some research centers have found the naturally potential ingredients, such as Carrot(1), green tea(3) and Almond(7) for reduced risk and treatment for Eczema.

Carrot is root vegetable with orange color normally, a sub spices of Daucus carota, belongings to the family Apiaceae, native to Asian and Europe. Its vitamin A, a nutritional intake showed to modify the rate of decline of visual acuity in retinitis pigmentosa(1).

According to the Harvard Medical School, in the study of retinal degeneration in subgroups of patients with retinitis pigmentosa, suggested, diet rich in vitamin A and omega-3 fatty acids found abundantly in almond for at least 2 years, slowed the decline in visual field sensitivity(2).In a randomized, controlled, double-masked trial of 225 nonsmoking patients, aged 18 to 60 years conducted by the Harvard Medical School, said, "Lutein supplementation of 12 mg/d slowed loss of midperipheral visual field on average among nonsmoking adults with retinitis pigmentosa taking vitamin A"(3).

Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Because of their health benefits, they have been cultivated for commercial purposes all over the world. Green tea extract is considered as one of most powerful antioxidant in common herbal supplement ameliorated the onset and progression of human RP through inhibited the photoreceptor apoptosis in animal model(4).
According to the study by the Evidence-Based Complementary and Alternative Medicine, catechin is a polyphenolic antioxidant commonly found in green tea, inhibited RP cell migration and adhesion, thereby providing potential preventive actions against Age-Related Macular Degeneration(AMD)(5).

Almond consists of an outer hull and a hard shell with the seed (nut) inside is native to the Middle East. It is most widely cultivated seed in the world for it economic and health benefit. Its phytochemical also exerted its antioxidant effect in inhibition of progression of retinitis pigmentos in many patients, according to the Harvard Medical School(6).

According to Dr. Hodge WG and colleagues at the University of Ottawa, in the review of 6 studies published between 1995 and 2004 met eligibility criteria, found that omega-3 fatty acids may slow the progression of retinitis pigmentosa, but definitive answers will require significantly more observational and interventional clinical research(7).

The combined green tea extract, vitamin A and omega 3 fatty acid found in green tea, carrot and almond respectively may contribute to further investigation of therapeutic natural ingredients for reduced risk and treatment of Retinitis pigmentosa.
People who are at increased risk of Retinitis pigmentosa due to aging or chronic illness should drink at least one serving daily and people with Retinitis pigmentosa should drink as much as they can, depending to digestive toleration.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/p/general-health.html

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca


References
(1) ω-3 intake and visual acuity in patients with retinitis pigmentosa receiving vitamin A by Berson EL1, Rosner B, Sandberg MA, Weigel-DiFranco C, Willett WC.(PubMed)
(2) Further evaluation of docosahexaenoic acid in patients with retinitis pigmentosa receiving vitamin A treatment: subgroup analyses by Berson EL1, Rosner B, Sandberg MA, Weigel-DiFranco C, Moser A, Brockhurst RJ, Hayes KC, Johnson CA, Anderson EJ, Gaudio AR, Willett WC, Schaefer EJ.(PubMed)
(3) Clinical trial of lutein in patients with retinitis pigmentosa receiving vitamin A by Berson EL1, Rosner B, Sandberg MA, Weigel-DiFranco C, Brockhurst RJ, Hayes KC, Johnson EJ, Anderson EJ, Johnson CA, Gaudio AR, Willett WC, Schaefer EJ.(PubMed)
(4) Green tea extract suppresses N-methyl-N-nitrosourea-induced photoreceptor apoptosis in Sprague-Dawley rats by Emoto Y1, Yoshizawa K, Kinoshita Y, Yuri T, Yuki M, Sayama K, Shikata N, Tsubura A.(PubMed)
(5) Botanical Compounds: Effects on Major Eye Diseases by Tuan-Phat Huynh,1,2,3 Shivani N. Mann,1,2 and Nawajes A. Mandal1,2,4,5(Hindawi Publishing Corporation)
(6) Retinitis pigmentosa by Hartong DT1, Berson EL, Dryja TP.(PubMed)
(7) The evidence for efficacy of omega-3 fatty acids in preventing or slowing the progression of retinitis pigmentosa: a systematic review by Hodge WG1, Barnes D, Schachter HM, Pan YI, Lowcock EC, Zhang L, Sampson M, Morrison A, Tran K, Miguelez M, Lewin G.(PubMed)