Scientists may have found a natural ingredient for the prevention and treatment of pituitary adenomas with no side effects, according to studies.
Anacardic acids are phenolic lipids, phytochemicals of the organic acid found abundantly in cashews, mangoes, etc.
Pituitary adenomas are noncancerous tumors occurred in the pituitary gland.
A pituitary tumor has a negative and strong implication of the production of the thyroid-stimulating hormone, leading to a rare case of hyperthyroidism which normally induces the unintentional weight loss.
Most cases of the pituitary adenomas start in the cell of the inner lining of the tissue of the pituitary gland, due to the alternation of DNA. The tumor is well contained in the gland with no tendency of spreading.
At the early stage, patients with benign tumor do not experience any symptoms. However, when the tumor is growing larger, it may suppress the healthy tissue in the gland or nearby nerve cells, leading to symptoms of a headache, vision loss, and severe pain.
Epidemiological studies suggested that depending on the stage of the pituitary tumor, patients can experience hormone overproduction and hormone deficiency, leading to certain hormonal related diseases.
Depending on the size of the tumor and its effect on the patient's health, surgery may be the only option, if the tumor is pressing on the optic nerves or overproducing certain hormones.
In the concern of morbidity and complication of therapy in patients with pituitary adenomas, researchers examined the effect of Anacardic acids, a natural histone acetyltransferase inhibitor, on pituitary adenoma cells.
Epidemiological studies suggested that the progression of the benign pituitary tumor, if not treated, is a prevalent risk factor of the onset of malignant tumor pathogenesis.
Injection of anacardic acid exerted a significant anti antiproliferative and cytotoxic effect on pituitary adenoma cells.
According to the flow cytometry and Western blotting assays, anacardic acid inhibition of the tested cell line was associated with an increase the functions of the protein involved in a number of cellular processes in programming cell death and through cell cycle arrest on the G1 phase.
The marker used to detect cancer cell apoptosis, Annexin A5 (or annexin V), a cellular protein in the annexin group also increased after injecting the cancer cell with Anacardic acids.
In vitro and in vivo researchers found that administration of a pan-caspase inhibitor that irreversibly inhibits enzymatic function and effective in blocking apoptosis in a variety of cell types under normal condition has failed to reverse anacardic acid-induced cell death.
These results suggested that the bioactive induced cancer cell apoptosis through a possible nonclassical mechanism.
Furthermore, Anacardic acid the anti-cancer effect also suppressed the function of the survivin protein functions to exhibit negative regulation of apoptosis or programmed cell death and X-linked inhibitor of apoptosis protein (XIAP) associated with the anti-apoptotic function.
More importantly, the bioactive compound was found to deactivate the antiapoptotic proteins associated with cellular survival and radioresistance and radiosensitized pituitary adenoma cells.
The findings indicated that the chemical compound inhibited the onset and progression of pituitary adenomas through promoting cell cycle arrest, cancer apoptosis, programming cell death through some known and unknown mechanisms.
Taken all together, Anacardic acids may be used for the prevention and treatment of pituitary adenomas with no side effects, pending to the result of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blog, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Reference
(1) Anacardic acid induces caspase-independent apoptosis and radiosensitizes pituitary adenoma cells by Sukumari-Ramesh S, Singh N, Jensen MA, Dhandapani KM, Vender JR.(PubMed)
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Permanently and Naturally, Eliminate All Types of Ovarian Cysts Within 2 Months
Thursday, February 20, 2020
Healthy Food Broccoli, the Potential Tumor Suppressor
Tumor suppressor proteins are types of genetic materials that protect the body against cell proliferation by regulating the activity of a variety of cellular genes involved in growth and cell cycle progression.
In other words, tumor-suppressor genes encode proteins that slow or inhibit progression through a range of mechanisms to protect the cell integrity against mutation including inhibiting proliferation, programming cell death and involving cell cycle arrest.
Proteins found in the cells of organisms are large, complex molecules that play many critical roles in maintaining the structure, function, and regulation of the body’s tissues and organs.
Proteins are made up of hundreds or thousands of smaller units called amino acids, attaching one to another in long chains.
The most common types of tumor-suppressor proteins are
* The retinoblastoma protein (Rb) is a tumor suppressor protein that has been found to induce dysfunction in several major cancers by preventing excessive cell growth and inhibiting cell cycle.
* p53 is also a tumor suppressor protein that plays a critical role in the regulation of cell division through its anti-proliferative activity.
In many cancer, the loss or inactivation of the tumor suppressor genes has shown to contribute to the abnormal proliferation of tumor cells.
Broccoli is a mustard/cabbage plant, belongings to the family Brassicaceae. The veggie has large flower heads, usually green in color with a mass of flower heads surrounded by leaves and evolved from a wild cabbage plant from the continent of Europe.
On finding a potential wholefood for the treatment of cancer, researchers examined the effect of Indole-3-Carbinol (I3C), a dietary compound found naturally in cruciferous vegetables, including broccoli and brussels sprouts on cell arrest of human reproductive cancer cells.
According to the I3C treatment on the tested cancer cell line, the bioactive compound increased both the transcripts and protein levels of the CDK2 inhibitor p21 associated with a tumor-suppressive gene linking to DNA damage cell cycle arrest through tumor protein p53, another tumor suppressor.
In other words, ablating p53 production prevented the I3C function to induce G1 arrest and p21 expression.
In cell division assays, the anti-proliferative activity of I3C was attributed to p53 protein stability and greater transactivation of p21 potential.
Based on the finding, researchers said, " I3C induced G1 arrest of human prostate cancer cells requires the induced production of the activated phosphorylated forms of p53, which stimulate transcription of the CDK2 inhibitor p21".
Taken altogether, broccoli processed a high amount of Indole-3-Carbinol may be considered a functional food for the prevention and treatment of prostate cancer, pending to the confirmation of the larger sample size and multicenter human study.
Intake of I3C in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Indole-3-carbinol mediated cell cycle arrest of LNCaP human prostate cancer cells requires the induced production of activated p53 tumor suppressor protein by Hsu JC1, Dev A, Wing A, Brew CT, Bjeldanes LF, Firestone GL. (PubMed)
In other words, tumor-suppressor genes encode proteins that slow or inhibit progression through a range of mechanisms to protect the cell integrity against mutation including inhibiting proliferation, programming cell death and involving cell cycle arrest.
Proteins found in the cells of organisms are large, complex molecules that play many critical roles in maintaining the structure, function, and regulation of the body’s tissues and organs.
Proteins are made up of hundreds or thousands of smaller units called amino acids, attaching one to another in long chains.
The most common types of tumor-suppressor proteins are
* The retinoblastoma protein (Rb) is a tumor suppressor protein that has been found to induce dysfunction in several major cancers by preventing excessive cell growth and inhibiting cell cycle.
* p53 is also a tumor suppressor protein that plays a critical role in the regulation of cell division through its anti-proliferative activity.
In many cancer, the loss or inactivation of the tumor suppressor genes has shown to contribute to the abnormal proliferation of tumor cells.
Broccoli is a mustard/cabbage plant, belongings to the family Brassicaceae. The veggie has large flower heads, usually green in color with a mass of flower heads surrounded by leaves and evolved from a wild cabbage plant from the continent of Europe.
On finding a potential wholefood for the treatment of cancer, researchers examined the effect of Indole-3-Carbinol (I3C), a dietary compound found naturally in cruciferous vegetables, including broccoli and brussels sprouts on cell arrest of human reproductive cancer cells.
According to the I3C treatment on the tested cancer cell line, the bioactive compound increased both the transcripts and protein levels of the CDK2 inhibitor p21 associated with a tumor-suppressive gene linking to DNA damage cell cycle arrest through tumor protein p53, another tumor suppressor.
In other words, ablating p53 production prevented the I3C function to induce G1 arrest and p21 expression.
In cell division assays, the anti-proliferative activity of I3C was attributed to p53 protein stability and greater transactivation of p21 potential.
Based on the finding, researchers said, " I3C induced G1 arrest of human prostate cancer cells requires the induced production of the activated phosphorylated forms of p53, which stimulate transcription of the CDK2 inhibitor p21".
Taken altogether, broccoli processed a high amount of Indole-3-Carbinol may be considered a functional food for the prevention and treatment of prostate cancer, pending to the confirmation of the larger sample size and multicenter human study.
Intake of I3C in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Indole-3-carbinol mediated cell cycle arrest of LNCaP human prostate cancer cells requires the induced production of activated p53 tumor suppressor protein by Hsu JC1, Dev A, Wing A, Brew CT, Bjeldanes LF, Firestone GL. (PubMed)
Wednesday, February 19, 2020
Healthy Food Broccoli's Sulforaphane (SFN) Inhibits Urologic Cancer Cells in Vitro
Urologic cancers are a class of medical conditions including
*Prostate cancer is a condition in which the cells of the prostate have become cancerous, causing abnormal cell growth with the possibility of spreading to the distant parts of the body.
Most prostate cancers are slow-growing and enlarged prostate and prostate cancer may be detected during physical (rectum) exams.
* Kidney cancer is a medical condition characterized by irregular cell growth in the tissue of kidneys.
At the later stage, the cancerous cells may travel a distance way to infect other organs' tissues.
For example, if kidney cancer spreads to the lung is called kidney cancer with lung metastases.
* Bladder cancer
The bladder is a hollow elastic organ in the center of the lower abdomen that collects urine from the kidneys and excreted them through the urethra.
Bladder cancer is the most common type of cancer that affects men twice as frequently as it affects women.
* Cancer of the renal pelvis and ureter is a cancer of renal pelvis on the top part of the ureter and the ureter which is a long tube that connects the kidney to the bladder
* Testicle cancer
Testicular Cancer is cancer that arises in the testicles (testes), located inside the scrotum. testicles form part of the male reproductive system, responding to the production and reproduction of male sex hormones and sperm.
* Cancer of the penis
Penis cancer is a type of irregular cell growth formed in the tissues of the penis.
* Urethra cancer
Urethral cancer is a type of medical condition caused by the growth of malignant cells in tissues of the urethra, the tube that carries urine from the bladder and out of the body.
The most common symptoms of urologic cancers are the difficulty starting to urinate or difficulty holding urine back, weak urine stream or interruption of stream, painful urination, pelvic discomfort, bone pain, erectile dysfunction (ED), painful ejaculation, blood in the urine and blood in the semen.
The joint study led by the National Cancer Center, Goyang, Korea, wrote, "During 1999-2012 (In Korean), urological cancer occurred in 155,991 patients (Table 1). The most common cancer was prostate cancer (66,812 patients) followed by bladder cancer (41,549 patients), kidney cancer (36,836 patients), renal pelvis and ureter cancer (7,537 patients), testis cancer (2,439 patients), and penile cancer (818 patients)".
Broccoli is a mustard/cabbage plant, belongings to the family Brassicaceae. The veggie has large flower heads, usually green in color and the mass of flower heads surrounded by leaves and evolved from a wild cabbage plant on the continent of Europe.
On finding a potential plant that processes anticarcinogenic activity, researchers examined the effects sulforaphane (SF), a natural compound sulforaphane (SFN) anti-urologic cancer effects.
According to the tested analysis, the application of SFN shows a remarkable anti-tumor effect in vitro and in vivo without exerting toxicity.
Furthermore, based on available evidence from epidemiological, in vitro, preclinical and early phase trials, SFN was not only available in standardized formulations, bioavailable- both systemically and in the bladder but also exerted a significant anti bladder cancer through multiple mechanisms.
Additionally, similar to its effects on urological cancer, SFN induced cancer apoptosis without causing cytotoxicity.
Collectively, researchers said, "sulforaphane (SFN) represents a promising potential chemopreventative agent in bladder cancer".
Taken altogether, Broccoli processed abundant bioactive compound SFN, which may be considered a functional food for the prevention and treatment of urologic tumors, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) The relevance of the natural HDAC inhibitor sulforaphane as a chemopreventive agent in urologic tumors by Juengel E1, Erb HHH2, Haferkamp A2, Rutz J3, Chun FK3, Blaheta RA. (PubMed)
(2) Current Trends in the Incidence and Survival Rate of Urological Cancers in Korea by Jae Young Joung, MD, Ph.D.,1 Jiwon Lim, MS,2 Chang-Mo Oh, MD, Ph.D.,2 Kyu-Won Jung, MS,2 Hyunsoon Cho, Ph.D.,2 Sung Han Kim, MD, Ph.D.,1 Ho Kyung Seo, MD, Ph.D.,1Weon Seo Park, MD, Ph.D.,1 Jinsoo Chung, MD, Ph.D.,1 Kang Hyun Lee, MD, Ph.D.,1 andYoung-Joo Won, Ph.D. (PMC)
(3) Sulforaphane for the chemoprevention of bladder cancer: molecular mechanism targeted approach by Andrew Leone,1 Gregory Diorio,1 Wade Sexton,1 Michael Schell,2 Mark Alexandrow,3Jed W. Fahey,4 and Nagi B. Kumar. (PubMed)
*Prostate cancer is a condition in which the cells of the prostate have become cancerous, causing abnormal cell growth with the possibility of spreading to the distant parts of the body.
Most prostate cancers are slow-growing and enlarged prostate and prostate cancer may be detected during physical (rectum) exams.
* Kidney cancer is a medical condition characterized by irregular cell growth in the tissue of kidneys.
At the later stage, the cancerous cells may travel a distance way to infect other organs' tissues.
For example, if kidney cancer spreads to the lung is called kidney cancer with lung metastases.
* Bladder cancer
The bladder is a hollow elastic organ in the center of the lower abdomen that collects urine from the kidneys and excreted them through the urethra.
Bladder cancer is the most common type of cancer that affects men twice as frequently as it affects women.
* Cancer of the renal pelvis and ureter is a cancer of renal pelvis on the top part of the ureter and the ureter which is a long tube that connects the kidney to the bladder
* Testicle cancer
Testicular Cancer is cancer that arises in the testicles (testes), located inside the scrotum. testicles form part of the male reproductive system, responding to the production and reproduction of male sex hormones and sperm.
* Cancer of the penis
Penis cancer is a type of irregular cell growth formed in the tissues of the penis.
* Urethra cancer
Urethral cancer is a type of medical condition caused by the growth of malignant cells in tissues of the urethra, the tube that carries urine from the bladder and out of the body.
The most common symptoms of urologic cancers are the difficulty starting to urinate or difficulty holding urine back, weak urine stream or interruption of stream, painful urination, pelvic discomfort, bone pain, erectile dysfunction (ED), painful ejaculation, blood in the urine and blood in the semen.
The joint study led by the National Cancer Center, Goyang, Korea, wrote, "During 1999-2012 (In Korean), urological cancer occurred in 155,991 patients (Table 1). The most common cancer was prostate cancer (66,812 patients) followed by bladder cancer (41,549 patients), kidney cancer (36,836 patients), renal pelvis and ureter cancer (7,537 patients), testis cancer (2,439 patients), and penile cancer (818 patients)".
Broccoli is a mustard/cabbage plant, belongings to the family Brassicaceae. The veggie has large flower heads, usually green in color and the mass of flower heads surrounded by leaves and evolved from a wild cabbage plant on the continent of Europe.
On finding a potential plant that processes anticarcinogenic activity, researchers examined the effects sulforaphane (SF), a natural compound sulforaphane (SFN) anti-urologic cancer effects.
According to the tested analysis, the application of SFN shows a remarkable anti-tumor effect in vitro and in vivo without exerting toxicity.
Furthermore, based on available evidence from epidemiological, in vitro, preclinical and early phase trials, SFN was not only available in standardized formulations, bioavailable- both systemically and in the bladder but also exerted a significant anti bladder cancer through multiple mechanisms.
Additionally, similar to its effects on urological cancer, SFN induced cancer apoptosis without causing cytotoxicity.
Collectively, researchers said, "sulforaphane (SFN) represents a promising potential chemopreventative agent in bladder cancer".
Taken altogether, Broccoli processed abundant bioactive compound SFN, which may be considered a functional food for the prevention and treatment of urologic tumors, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) The relevance of the natural HDAC inhibitor sulforaphane as a chemopreventive agent in urologic tumors by Juengel E1, Erb HHH2, Haferkamp A2, Rutz J3, Chun FK3, Blaheta RA. (PubMed)
(2) Current Trends in the Incidence and Survival Rate of Urological Cancers in Korea by Jae Young Joung, MD, Ph.D.,1 Jiwon Lim, MS,2 Chang-Mo Oh, MD, Ph.D.,2 Kyu-Won Jung, MS,2 Hyunsoon Cho, Ph.D.,2 Sung Han Kim, MD, Ph.D.,1 Ho Kyung Seo, MD, Ph.D.,1Weon Seo Park, MD, Ph.D.,1 Jinsoo Chung, MD, Ph.D.,1 Kang Hyun Lee, MD, Ph.D.,1 andYoung-Joo Won, Ph.D. (PMC)
(3) Sulforaphane for the chemoprevention of bladder cancer: molecular mechanism targeted approach by Andrew Leone,1 Gregory Diorio,1 Wade Sexton,1 Michael Schell,2 Mark Alexandrow,3Jed W. Fahey,4 and Nagi B. Kumar. (PubMed)
Herbal Angelica Processes Anti-diabetes and Immunomodulatory Activities
Diabetes is a chronic condition caused by insufficient insulin entering the bloodstream to regulate the glucose.
In other words, diabetes occurs when cells in the pancreas dying off or receptor sites clogged up by fat and cholesterol. In some cases, diabetes is also caused by allergic reactions of cells in the immune system.
The most common symptoms of diabetes are excessive thirst and hunger, frequent urination, unintended weight loss or gain, frequent fatigue, irritability and gastrointestinal symptoms such as nausea.
Some patients may also experience symptoms of blurred vision and slow wound healing or ulcer.
Prediabetes is caused by unhealthy diets with high saturated fat, smoking, and excessive alcohol drinking. Therefore, understanding prediabetes is a very important issue for prediabetics, because with proper diets, quit smoking, controlled alcohol intake and exercises, prediabetes can be reversed or delayed.
People with the glucose level between 111mg/dl-125 mg/dl are considered pre-diabetics.
Hyperglycemia, a medical condition of abnormally high blood glucose, is a major concern, in people with both type 1 and type 2 diabetes.
Most cases of hyperglycemia occurred in patients who do not manage their diabetes properly.
Hyperglycemia, a hallmark of diabetes has been found to induce diabetics complications, including neuropathy, nephropathy, and retinopathy).
According to statistics, diabetes is one of the most common diseases in the US. Approximately 10% or 29.1 million people in the United States have diabetes, accompanied by 8.1 million that are undiagnosed and unaware of their condition.
About 1.4 million new cases of diabetes are diagnosed in the United States every year. More than one in every 10 adults who are 20 years or older has diabetes.
The immune system is the set of cells and their activity against antigens or infectious agents that comprise the body's defense system against diseases.
Immunomodulatory activity is an action that improves the underactive immune function that is susceptible to the invasion of the foreign microorganism and inhibits the overactive immune system that causes autoimmune diseases.
Angelica or Dang Qui is a herb of Genus Angelica from the family Apiaceae, indigenous to China.
The herb has been used as a Queen herb in traditional Chinese medicine antispasmodic and vasodilatory agent, and to balance the hormones in women for a normal menstrual cycle and menstruation and strengthen heart, spleen, kidneys, and liver for both men and women, etc. In other words, it is used to treat gynecological ailments, fatigue, mild anemia, and high blood pressure. It has analgesic, anti-inflammatory, etc.
On finding a herbal medicine for the prevention and treatment of diabetes, researchers investigated the effects of the decoction HemoHIM on hyperglycemia and the immune response in diabetic mice.
Mice selected to the study were divided into nondiabetic and diabetic mice induced by a single injection of streptozotocin (STZ, 200 mg/kg, i.p.) orally administered HemoHIM (100 mg/kg) once a day for 4 weeks.
Diabetic mice with HemoHIM showed improved hyperglycemia and glucose tolerance as well as elevated plasma insulin levels with the preservation of insulin staining in pancreatic β-cells, compared to the diabetic control group.
Furthermore, HemoHIM treatment restored parameters associated with the onset of diabetes including thymus weight, white blood cells, lymphocyte numbers, and splenic lymphocyte populations (CD4(+) T and CD8(+) T), which were reduced in diabetic mice.
Moreover, HemoHIM also animalized the IFN-γ production associated with innate and adaptive immunity in response to Con A stimulation in facilitating mediated T cell proliferation.
Based on the results, researchers said, "HemoHIM may have potential as a glucose-lowering and immunomodulatory agent by enhancing the immune function of pancreatic β-cells in STZ-induced diabetic mice".
Taken altogether, Herbal Angelica used in the combination with other herbal medicines for the treatment of diabetes, pending to larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Immunomodulatory and Antidiabetic Effects of a New Herbal Preparation (HemoHIM) on Streptozotocin-Induced Diabetic Mice by Kim JJ1, Choi J1, Lee MK2, Kang KY3, Paik MJ3, Jo SK4, Jung U4, Park HR4, Yee ST. (PubMed)
In other words, diabetes occurs when cells in the pancreas dying off or receptor sites clogged up by fat and cholesterol. In some cases, diabetes is also caused by allergic reactions of cells in the immune system.
The most common symptoms of diabetes are excessive thirst and hunger, frequent urination, unintended weight loss or gain, frequent fatigue, irritability and gastrointestinal symptoms such as nausea.
Some patients may also experience symptoms of blurred vision and slow wound healing or ulcer.
Prediabetes is caused by unhealthy diets with high saturated fat, smoking, and excessive alcohol drinking. Therefore, understanding prediabetes is a very important issue for prediabetics, because with proper diets, quit smoking, controlled alcohol intake and exercises, prediabetes can be reversed or delayed.
People with the glucose level between 111mg/dl-125 mg/dl are considered pre-diabetics.
Hyperglycemia, a medical condition of abnormally high blood glucose, is a major concern, in people with both type 1 and type 2 diabetes.
Most cases of hyperglycemia occurred in patients who do not manage their diabetes properly.
Hyperglycemia, a hallmark of diabetes has been found to induce diabetics complications, including neuropathy, nephropathy, and retinopathy).
According to statistics, diabetes is one of the most common diseases in the US. Approximately 10% or 29.1 million people in the United States have diabetes, accompanied by 8.1 million that are undiagnosed and unaware of their condition.
About 1.4 million new cases of diabetes are diagnosed in the United States every year. More than one in every 10 adults who are 20 years or older has diabetes.
The immune system is the set of cells and their activity against antigens or infectious agents that comprise the body's defense system against diseases.
Immunomodulatory activity is an action that improves the underactive immune function that is susceptible to the invasion of the foreign microorganism and inhibits the overactive immune system that causes autoimmune diseases.
Angelica or Dang Qui is a herb of Genus Angelica from the family Apiaceae, indigenous to China.
The herb has been used as a Queen herb in traditional Chinese medicine antispasmodic and vasodilatory agent, and to balance the hormones in women for a normal menstrual cycle and menstruation and strengthen heart, spleen, kidneys, and liver for both men and women, etc. In other words, it is used to treat gynecological ailments, fatigue, mild anemia, and high blood pressure. It has analgesic, anti-inflammatory, etc.
On finding a herbal medicine for the prevention and treatment of diabetes, researchers investigated the effects of the decoction HemoHIM on hyperglycemia and the immune response in diabetic mice.
Mice selected to the study were divided into nondiabetic and diabetic mice induced by a single injection of streptozotocin (STZ, 200 mg/kg, i.p.) orally administered HemoHIM (100 mg/kg) once a day for 4 weeks.
Diabetic mice with HemoHIM showed improved hyperglycemia and glucose tolerance as well as elevated plasma insulin levels with the preservation of insulin staining in pancreatic β-cells, compared to the diabetic control group.
Furthermore, HemoHIM treatment restored parameters associated with the onset of diabetes including thymus weight, white blood cells, lymphocyte numbers, and splenic lymphocyte populations (CD4(+) T and CD8(+) T), which were reduced in diabetic mice.
Moreover, HemoHIM also animalized the IFN-γ production associated with innate and adaptive immunity in response to Con A stimulation in facilitating mediated T cell proliferation.
Based on the results, researchers said, "HemoHIM may have potential as a glucose-lowering and immunomodulatory agent by enhancing the immune function of pancreatic β-cells in STZ-induced diabetic mice".
Taken altogether, Herbal Angelica used in the combination with other herbal medicines for the treatment of diabetes, pending to larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Immunomodulatory and Antidiabetic Effects of a New Herbal Preparation (HemoHIM) on Streptozotocin-Induced Diabetic Mice by Kim JJ1, Choi J1, Lee MK2, Kang KY3, Paik MJ3, Jo SK4, Jung U4, Park HR4, Yee ST. (PubMed)
Tuesday, February 18, 2020
Beta-sitosterol Oxidation Products (SOPs) Exerts the Similar Side Effects as of Cholesterol Oxidation
Antioxidants are stable atom that plays a critical role in protecting the body against the attack of free radicals.
In other words, antioxidants inhibited the onset of free radical before they can cause a chain reaction in facilitating the protein, lipid and cell damage.
Antioxidants can either produced by the liver or intake from dietary sources. Under normal conditions, antioxidant enzymes produced by the body in a healthy individual are good enough to counter the bombardment of free radical attacks.
There are 3 main types of antioxidants found in nature, including
* Antioxidant enzymes produced by the host, including superoxide dismutase (SOD), glutathione peroxidase, glutathione reductase, and catalases.
* Antioxidants vitamins, that may be injected from the dietary sources such as fruits and vegetables, including vitamins A, C, D, and E. Most antioxidant vitamins are considered free radical scavengers that gobble up free radicals before they can induce a cascade of damage.
* Antioxidant Phytochemicals found in the plant including second metabolites.
Antioxidants keep our bodies functioning properly by reducing the risk of diseases associated with oxidative stress.
Oxidative stress is a result of an imbalance of the ratio of free radicals and antioxidants in the body.
Free radicals are highly reactive molecules with an unpaired electron on the outer ring of the atom.
Due to its nature to become stable, free radicals readily to donate or steal an electron from other molecules, leading to the chain of domino's effect that can not be stopped until either the electrons are paired or inhibited by antioxidants.
This chain of reaction is the cause of oxidative stress, a condition is associated with either overexpression of free radicals or depletion of antioxidant enzymes produced by the host organs.
Beta-Sitosterol is a phytochemical in the class of Phytosterols, belongings to the group of Lipids, found abundantly in avocados, rice bran, wheat germ, corn oils, fennel, peanuts, soybeans, hawthorn, basil, buckwheat. etc.
On finding a potential phytochemical for the prevention and treatment of diseases associated with oxidative stress, researchers examined the beta-sitosterol oxidation products (SOPs) negative health effects.
SOPs were found to elevate the level of reactive oxygen species in rat aortic endothelial cells, and the effects were reversed by antioxidants tempol, tiron, or diphenylene iodonium
In other words, SOPs elevated the levels of cholesterol have a strong implication on the risk of atherosclerosis, cardiovascular diseases.
According to the experimental analysis,
* Both cholesterol and beta-sitosterol were thermally unstable with 75% of cholesterol and beta-sitosterol being oxidized at 180 degrees C for 2 h.
* The oxidation behavior of beta-sitosterol was similar to that of cholesterol in terms of oxidative rate and oxidation products.
* Both cholesterol and beta-sitosterol were oxidized more slowly in corn oil, lard, and olive oil,
More precisely, the slowed oxidation of cholesterol and beta-sitosterol was attributable to the unsaponified antioxidants present in these fat and oils.
* However, GTC, alpha-tocopherol, and quercetin were more effective than green tea catechins (GTC) in preventing the oxidation of cholesterol and beta-sitosterol.
Taken altogether, beta-sitosterol oxidation products (SOPs) used as a supplement should be taken with care as they exerted similar and negative health benefits, pending to the confirmation of the larger sample size and multicenter human study.
Intake of beta-Sitosterol in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Oxidation of cholesterol and beta-sitosterol and prevention by natural antioxidants by Xu G1, Guan L, Sun J, Chen ZY. (PubMed)
In other words, antioxidants inhibited the onset of free radical before they can cause a chain reaction in facilitating the protein, lipid and cell damage.
Antioxidants can either produced by the liver or intake from dietary sources. Under normal conditions, antioxidant enzymes produced by the body in a healthy individual are good enough to counter the bombardment of free radical attacks.
There are 3 main types of antioxidants found in nature, including
* Antioxidant enzymes produced by the host, including superoxide dismutase (SOD), glutathione peroxidase, glutathione reductase, and catalases.
* Antioxidants vitamins, that may be injected from the dietary sources such as fruits and vegetables, including vitamins A, C, D, and E. Most antioxidant vitamins are considered free radical scavengers that gobble up free radicals before they can induce a cascade of damage.
* Antioxidant Phytochemicals found in the plant including second metabolites.
Antioxidants keep our bodies functioning properly by reducing the risk of diseases associated with oxidative stress.
Oxidative stress is a result of an imbalance of the ratio of free radicals and antioxidants in the body.
Free radicals are highly reactive molecules with an unpaired electron on the outer ring of the atom.
Due to its nature to become stable, free radicals readily to donate or steal an electron from other molecules, leading to the chain of domino's effect that can not be stopped until either the electrons are paired or inhibited by antioxidants.
This chain of reaction is the cause of oxidative stress, a condition is associated with either overexpression of free radicals or depletion of antioxidant enzymes produced by the host organs.
Beta-Sitosterol is a phytochemical in the class of Phytosterols, belongings to the group of Lipids, found abundantly in avocados, rice bran, wheat germ, corn oils, fennel, peanuts, soybeans, hawthorn, basil, buckwheat. etc.
On finding a potential phytochemical for the prevention and treatment of diseases associated with oxidative stress, researchers examined the beta-sitosterol oxidation products (SOPs) negative health effects.
SOPs were found to elevate the level of reactive oxygen species in rat aortic endothelial cells, and the effects were reversed by antioxidants tempol, tiron, or diphenylene iodonium
In other words, SOPs elevated the levels of cholesterol have a strong implication on the risk of atherosclerosis, cardiovascular diseases.
According to the experimental analysis,
* Both cholesterol and beta-sitosterol were thermally unstable with 75% of cholesterol and beta-sitosterol being oxidized at 180 degrees C for 2 h.
* The oxidation behavior of beta-sitosterol was similar to that of cholesterol in terms of oxidative rate and oxidation products.
* Both cholesterol and beta-sitosterol were oxidized more slowly in corn oil, lard, and olive oil,
More precisely, the slowed oxidation of cholesterol and beta-sitosterol was attributable to the unsaponified antioxidants present in these fat and oils.
* However, GTC, alpha-tocopherol, and quercetin were more effective than green tea catechins (GTC) in preventing the oxidation of cholesterol and beta-sitosterol.
Taken altogether, beta-sitosterol oxidation products (SOPs) used as a supplement should be taken with care as they exerted similar and negative health benefits, pending to the confirmation of the larger sample size and multicenter human study.
Intake of beta-Sitosterol in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Oxidation of cholesterol and beta-sitosterol and prevention by natural antioxidants by Xu G1, Guan L, Sun J, Chen ZY. (PubMed)
Common Fig or Fig (Ficus carica), the Anti-Cardiovascular Diseases Whole Food
Cardiovascular disease (CVD) is a group of conditions associated with the heart and blood vessels.
The heart formed part of the circulatory system is a muscular organ that pumps blood through the blood vessels to nourish the body tissues and organs.
Most cases of heart dysfunction are associated with the reduced function of the heart muscle, leading to reduce blood flow that facilitates heart failure and the backup of blood into the lungs or rest of the body.
Heart disease is a class of diseases associated with interruption of blood flow in the blood vessel or damage of the heart tissue, including coronary artery diseases (CAD) such as angina and myocardial infarction.
According to the statistics provided by the US government, heart disease is a leading cause of death in the US. Over 600,000 died of heart disease, every year including 370,000 people died of coronary heart disease (CHD), accounting for 1 in 4 deaths.
Believe it or not, women are 4 times more likely to die from heart disease than breast cancer and 2/3 of women are not aware of heart disease is such a risk for them, according to the Jean Hailes for Women Health in the article cardiovascular health.
The most common symptoms of heart disease are poor appetite, weight loss, shortness of breath, sudden collapse, blood clots and stunted growth found in children.
Coronary heart disease (CHD) is the most common type of heart disease, that kills over 370,000 people annually.
The causes of cardiovascular diseases are associated with the accumulation of plaques in the arteries, impeding the blood flow which carries the nutrients and oxygen to the heart, causing damage to the heart tissue and reduced function of the arteries.
In other words, high blood pressure, high blood cholesterol, smoking, diabetes, weight, depression and family history associated with the early onset of plaques accumulated and impeding function of the arteries are the prevalent risk factors of cardiovascular diseases.
Many people know that tobacco use is associated with an increased risk of bladder cancer, but most of them do not know that smoking is one of the leading causes of cardiovascular diseases.
Fig is a species of F. Carica, belonging to the family Moraceae. It is a deciduous shrub, native to Southeast Asia. The tree can grow to a height of 33 ft and the fruit can be as large as 2.0 inches.
On finding a natural whole food for the treatment of diseases associated with oxidative stress, researchers examined the cardioprotective effects of the aqueous extracts of Cydonia oblonga Mill. fruit (ACO) and Ficus carica L. fruit (AFC) against DOX-induced cardiotoxicity.
In cardiomyocytes toxicity that was induced in male Sprague Dawley rats by intraperitoneal (ip) injections of 2.5 mg/kg DOX 3 times per week for a period of 2 weeks induced heart failure,
* The injection of the extracts showed a strong effect on mitochondrial oxidative stress that inhibits the damage the mitochondria and dysfunction.
More precisely, ACO and AFC ameliorated mitochondrial dysfunction induced by the DOX3 in the isolated mitochondria and prevented mitochondrial reactive oxygen species formation.
* ACO and AFC ameliorated mitochondrial dysfunction in the isolated mitochondria and prevented mitochondrial reactive oxygen species formation associated with membrane lipid peroxidation, mitochondrial swelling, mitochondrial membrane potential collapse (%ΔΨm), and cytochrome c release.
* The antioxidant enzymes produced by the host such as glutathione levels and succinate dehydrogenase activity were significantly increased by the extracts.
In other words, ACO and AFC have beneficial effects against DOX cardiotoxicity which mediated by attenuating mitochondrial dysfunction.
Based on the results, researchers wrote, " (...The results) can be suggested that quince and fig may increase the therapeutic index of DOX".
Taken altogether, common fig may be considered a natural anti-CVD, pending to the confirmation of the larger sample size and multicenter human study.
Intake of SFN in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1)Mitochondria as a Target for the Cardioprotective Effects of Cydonia oblonga Mill. and Ficus carica L. in Doxorubicin-Induced Cardiotoxicity by Gholami S1, Hosseini MJ2, Jafari L1, Omidvar F1, Kamalinejad M3, Mashayekhi V1, Hosseini SH4, Kardan A1, Pourahmad J3, Eskandari MR. (PubMed)
The heart formed part of the circulatory system is a muscular organ that pumps blood through the blood vessels to nourish the body tissues and organs.
Most cases of heart dysfunction are associated with the reduced function of the heart muscle, leading to reduce blood flow that facilitates heart failure and the backup of blood into the lungs or rest of the body.
Heart disease is a class of diseases associated with interruption of blood flow in the blood vessel or damage of the heart tissue, including coronary artery diseases (CAD) such as angina and myocardial infarction.
According to the statistics provided by the US government, heart disease is a leading cause of death in the US. Over 600,000 died of heart disease, every year including 370,000 people died of coronary heart disease (CHD), accounting for 1 in 4 deaths.
Believe it or not, women are 4 times more likely to die from heart disease than breast cancer and 2/3 of women are not aware of heart disease is such a risk for them, according to the Jean Hailes for Women Health in the article cardiovascular health.
The most common symptoms of heart disease are poor appetite, weight loss, shortness of breath, sudden collapse, blood clots and stunted growth found in children.
Coronary heart disease (CHD) is the most common type of heart disease, that kills over 370,000 people annually.
The causes of cardiovascular diseases are associated with the accumulation of plaques in the arteries, impeding the blood flow which carries the nutrients and oxygen to the heart, causing damage to the heart tissue and reduced function of the arteries.
In other words, high blood pressure, high blood cholesterol, smoking, diabetes, weight, depression and family history associated with the early onset of plaques accumulated and impeding function of the arteries are the prevalent risk factors of cardiovascular diseases.
Many people know that tobacco use is associated with an increased risk of bladder cancer, but most of them do not know that smoking is one of the leading causes of cardiovascular diseases.
Fig is a species of F. Carica, belonging to the family Moraceae. It is a deciduous shrub, native to Southeast Asia. The tree can grow to a height of 33 ft and the fruit can be as large as 2.0 inches.
On finding a natural whole food for the treatment of diseases associated with oxidative stress, researchers examined the cardioprotective effects of the aqueous extracts of Cydonia oblonga Mill. fruit (ACO) and Ficus carica L. fruit (AFC) against DOX-induced cardiotoxicity.
In cardiomyocytes toxicity that was induced in male Sprague Dawley rats by intraperitoneal (ip) injections of 2.5 mg/kg DOX 3 times per week for a period of 2 weeks induced heart failure,
* The injection of the extracts showed a strong effect on mitochondrial oxidative stress that inhibits the damage the mitochondria and dysfunction.
More precisely, ACO and AFC ameliorated mitochondrial dysfunction induced by the DOX3 in the isolated mitochondria and prevented mitochondrial reactive oxygen species formation.
* ACO and AFC ameliorated mitochondrial dysfunction in the isolated mitochondria and prevented mitochondrial reactive oxygen species formation associated with membrane lipid peroxidation, mitochondrial swelling, mitochondrial membrane potential collapse (%ΔΨm), and cytochrome c release.
* The antioxidant enzymes produced by the host such as glutathione levels and succinate dehydrogenase activity were significantly increased by the extracts.
In other words, ACO and AFC have beneficial effects against DOX cardiotoxicity which mediated by attenuating mitochondrial dysfunction.
Based on the results, researchers wrote, " (...The results) can be suggested that quince and fig may increase the therapeutic index of DOX".
Taken altogether, common fig may be considered a natural anti-CVD, pending to the confirmation of the larger sample size and multicenter human study.
Intake of SFN in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1)Mitochondria as a Target for the Cardioprotective Effects of Cydonia oblonga Mill. and Ficus carica L. in Doxorubicin-Induced Cardiotoxicity by Gholami S1, Hosseini MJ2, Jafari L1, Omidvar F1, Kamalinejad M3, Mashayekhi V1, Hosseini SH4, Kardan A1, Pourahmad J3, Eskandari MR. (PubMed)
Monday, February 17, 2020
Cranberry, a Natural Antioxidant Whole Food
Antioxidants are stable molecules that inhibited free radicals that cause oxidative stress if overexpressed.
Oxidative stress-related conditions are the class of diseases associated with cellular damage, including the alternation of cell DNA, and damage of lipid and protein.
Oxidative stress can be acute or chronic. Acute oxidative stress caused by suddenly burst of free radical due to stress or external sources, in most cases can be inhibited by increasing antioxidant enzymes by the lung.
Chronic oxidative stress is caused by the unbalanced ratio of free radicals and antioxidant enzymes produced by our body. The condition is either caused by oner expression of free radicals or depletion of antioxidant enzymes or both.
There are many risk factors that cause oxidative stress. However, in the concerns of the prevalence of chronic diseases associated with the Western diet, some researchers suggested that the link of the oxidative diseases in the Western world may be resulted by the promotion of the Western diet over the past few decades.
The list of chronic diseases caused by cell oxidation is very long, including atherosclerosis, cancer, diabetics, rheumatoid arthritis, post-ischemic perfusion injury, myocardial infarction, cardiovascular diseases, chronic inflammation, stroke.
The most common causes of oxidative stress are overexpression of free radicals in the induction of a chain reaction.
Due to the unstable nature of free radicals with unpaired electrons in the outer ring, free radicals are ready to donate or intercept the electrons from other atoms, leading to a chain reaction that can not be stopped until the outring electron are either paired or inhibited by antioxidants.
Contrast to the general belief, the damage caused by free radicals are overly exaggerated, under normal condition, free radicals produced by the internal or external source are needed by our body on cellular responses and immune function.
However, overexpression of free radicals also known as oxidative stress can be a danger to our health.
Cranberry is an evergreen dwarf shrub, genus Vaccinium, belongings to the family Ericaceae, native to Northern America and Southern Asia. Because of its health benefits, cranberry has been cultivated in some parts of the world for commercial profit and used in traditional and herbal medicine to treat wounds, urinary disorders, diarrhea, diabetes, stomach ailments, and liver problems.
On finding a potential compound for the treatment of diseases associated with oxidative stress, researchers examined the effect of cranberry juice (CJ) antioxidant activity.
According to the tested analysis on the consumption of high fructose corn syrup (HFCS) and ascorbate with CJ antioxidants or without CJ (control) given to 10 normal individuals after an overnight fast that was measured 6 times over 7 h after the consumption of a single 240 mL.
* People who consumed HFCS and ascorbate showed a slight decrease in plasma antioxidant capacity at all time points and an increase of oxidative stress.
* Compared to high fructose corn syrup (HFCS) and ascorbate, CJ increased the plasma antioxidant capacity significantly at all time points.
* Most importantly, levels of postprandial triglycerides associated with oxidative stress and antioxidant activity was significantly lower in the CJ group compared to.the high fructose corn syrup (HFCS) and ascorbate group.
Based on the findings, researchers aid, "Cranberries are an excellent source of high-quality antioxidants and should be examined in human supplementation studies".
Taken altogether, cranberry may be considered a remedy for the enhancement of the antioxidant activity, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Cranberries and cranberry products: powerful in vitro, ex vivo, and in vivo sources of antioxidants by Vinson JA1, Bose P, Proch J, Al Kharrat H, Samman N. (PubMed)
(2) Pure Polyphenols and Cranberry Juice High in Anthocyanins Increase Antioxidant Capacity in Animal Organs by Bariexca T1, Ezdebski J1, Redan BW2, Vinson J. (PubMed)
Oxidative stress-related conditions are the class of diseases associated with cellular damage, including the alternation of cell DNA, and damage of lipid and protein.
Oxidative stress can be acute or chronic. Acute oxidative stress caused by suddenly burst of free radical due to stress or external sources, in most cases can be inhibited by increasing antioxidant enzymes by the lung.
Chronic oxidative stress is caused by the unbalanced ratio of free radicals and antioxidant enzymes produced by our body. The condition is either caused by oner expression of free radicals or depletion of antioxidant enzymes or both.
There are many risk factors that cause oxidative stress. However, in the concerns of the prevalence of chronic diseases associated with the Western diet, some researchers suggested that the link of the oxidative diseases in the Western world may be resulted by the promotion of the Western diet over the past few decades.
The list of chronic diseases caused by cell oxidation is very long, including atherosclerosis, cancer, diabetics, rheumatoid arthritis, post-ischemic perfusion injury, myocardial infarction, cardiovascular diseases, chronic inflammation, stroke.
The most common causes of oxidative stress are overexpression of free radicals in the induction of a chain reaction.
Due to the unstable nature of free radicals with unpaired electrons in the outer ring, free radicals are ready to donate or intercept the electrons from other atoms, leading to a chain reaction that can not be stopped until the outring electron are either paired or inhibited by antioxidants.
Contrast to the general belief, the damage caused by free radicals are overly exaggerated, under normal condition, free radicals produced by the internal or external source are needed by our body on cellular responses and immune function.
However, overexpression of free radicals also known as oxidative stress can be a danger to our health.
Cranberry is an evergreen dwarf shrub, genus Vaccinium, belongings to the family Ericaceae, native to Northern America and Southern Asia. Because of its health benefits, cranberry has been cultivated in some parts of the world for commercial profit and used in traditional and herbal medicine to treat wounds, urinary disorders, diarrhea, diabetes, stomach ailments, and liver problems.
On finding a potential compound for the treatment of diseases associated with oxidative stress, researchers examined the effect of cranberry juice (CJ) antioxidant activity.
According to the tested analysis on the consumption of high fructose corn syrup (HFCS) and ascorbate with CJ antioxidants or without CJ (control) given to 10 normal individuals after an overnight fast that was measured 6 times over 7 h after the consumption of a single 240 mL.
* People who consumed HFCS and ascorbate showed a slight decrease in plasma antioxidant capacity at all time points and an increase of oxidative stress.
* Compared to high fructose corn syrup (HFCS) and ascorbate, CJ increased the plasma antioxidant capacity significantly at all time points.
* Most importantly, levels of postprandial triglycerides associated with oxidative stress and antioxidant activity was significantly lower in the CJ group compared to.the high fructose corn syrup (HFCS) and ascorbate group.
Based on the findings, researchers aid, "Cranberries are an excellent source of high-quality antioxidants and should be examined in human supplementation studies".
Taken altogether, cranberry may be considered a remedy for the enhancement of the antioxidant activity, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Cranberries and cranberry products: powerful in vitro, ex vivo, and in vivo sources of antioxidants by Vinson JA1, Bose P, Proch J, Al Kharrat H, Samman N. (PubMed)
(2) Pure Polyphenols and Cranberry Juice High in Anthocyanins Increase Antioxidant Capacity in Animal Organs by Bariexca T1, Ezdebski J1, Redan BW2, Vinson J. (PubMed)
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