Environment natural occurring compounds such as lead; mercury; radon, formaldehyde; benzene; and cadmium. and man-made compounds such as BPA phthalates and pesticides accumulated without notices by the host also can cause endocrine disruption and organs failure.
Toxins can also be accumulated due to long-term intake of certain conventional medicine such as Amiodarone (Cordarone), antibiotics, diuresis,.... and beta-blockers, anti-depressants and cytotoxic drugs or cytostatics used for the treatment of cancers.
These types of harmful substances are toxic. In order to protect and maintain normal function of our body, every day, our body's detoxifying organs must work overtime to get rid of them.
However, if they fail, these toxins may cause a disruption of hormone production, damage of our body's detoxification organs and weakening of our immune system, resulting in hormone imbalance and development of chronic illness.
Herbal medicine has a strong effect in colon cleansing, including
1. Flaxseed
Flaxseed containing high amounts of omega 3 fatty acid, fiber and lignan not only helps in controlling cholesterol in the bloodstream and provides essential nutrition to our body, but its fiber also softens the stool and promote bowel movements for the relief of constipation by removing all toxins accumulated in the colon.
According to the study by the Mercer University, Atlanta, flax seed with abundant Omega-3 fatty acids, such as α-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA), exerted a significant effect in protect the colon health through heightening colonic free fatty acid receptor 4 (FFAR4) and actin expression with function in mobility and contraction of cells during cell division, and reducing expression of the pro-inflammatory cytokine TNF-α compared to animals fed control diets(1).
Dr. Gomides AF, at the Federal University of Juiz de Fora in the investigation of the effect in
defatted flaxseed meal and risk precancerous colon lesions in C57BL/6 mice said, 'The rats consuming defatted flaxseed meals showed lesions with lower multiplicity and a reduced incidence of lesions".
Some researchers also suggested that adding a portion of flaxseed (Linum usitatissimum L.) and its total non-digestible fraction may have a strong effect in the inhibited azoxymethane (AOM)-induced colon (toxicity) cancer in Sprague Dawley rats(3).
2. Psyllium Psyllium
Psyllium contains about 70% soluble fiber and 30% insoluble fiber.
Besides having a proven record in Chinese medicine in treating high levels of cholesterol, its fiber portion also is used to treat constipation by softening stools and easing bowel movements.
According to the joint study led by the Institute for Genomics and Multiscale Biology, in the investigation of interactions between dietary ingredients, nutrients, and the microbiota in specific pathogen-free (SPF) and germ-free (GF) mice showed that application of all tested fibers reduces the severity of colitis in SPF mice, but not in GF mice or mice were given antibiotics.
In compared to other tested fiber, psyllium fiber reduced the severity of colitis effects through improvement of microbiota-dependent and microbiota-independent mechanisms.
If used combinatorial perturbations to dietary casein protein, psyllium fiber exerted a significant effect in reduced intestinal permeability, gut microbial density, and development of intestinal inflammation.
Truly, higher intakes of dietary fiber are linked to improvement of gut health.
Some researchers also suggested, "fiber undergoes partial or total fermentation in the distal small bowel and colon leading to the production of short-chain fatty acids and gas, thereby affecting gastrointestinal function and sensation"(5).
3. Bentonite clay or liquid clay
Bentonite clay is a natural clay that comes from volcanic ash.
Taken internally, the adsorbent action of bentonite eliminates and removes toxic material from the intestine.
According to the study by Shiraz University of Medical Sciences, bentonite clay may be used as a detoxifying agent because of its poly-cationic nature(6),
In T-2 is a trichothecene mycotoxin, injection of bentonite for 2 weeks before T-2 toxicosis, showed a significant increase in fecal excretion of this toxin(6)
Furthermore, bentonite may be used in humans as a dietary intervention to prevent and cure aflatoxin toxicity. if it does not affect the serum concentrations of important vitamins and nutrient minerals in humans(6).
4. Buckthorn Bark
Buckthorn bark is native to Europe and parts of western Asia.
The herb contains anthraquinones that stimulate intestinal movement by easing water to the intestines. These results suggested that buckthorn bark may have a strong impact in softened stool and removed toxins accumulated in the intestine.
In the article posted at the Whole Health Chicago, the author wrote, "(anthraquinones) ease constipation. The compounds in buckthorn bark increase the colon’s ability to spontaneously contract. They also reduce water absorption by the intestines, which means more liquid is left in the colon. This produces larger volume and softer stools, which in turn eases constipation"(7)
5. Cascara sagrada
Cascara sagrada is known to tone the relaxed intestinal muscles in the digestive system.
Intake of cascara sagrada promotes the digestive process in the prevention of digestive dysfunction such as chronic constipation.
In the study to assess aloe-emodin anthrone (AEA), the major compound found in cascara sagrada in the rat colonic mucosa using a Using-type chamber, researcher showed that AEA is effective in absorption of enhancers such as pyrilamine, histamine H(1) receptor antagonist and ketotifen without damage of the colon membrane and causing cytotoxicity(8).
Dr. Kai M, the lead scientist, after taking into account of other co and confounders, said, " AEA stimulates mast cells within the colonic mucosa to release histamine, which probably binds to the H(1) receptor. The intracellular PKC route activated by H(1) receptor activation enhances the permeability of water-soluble and poorly permeable drugs via the opening of tight junctions in rat colonic membrane"(8).
Finally, intake of herbal supplements should be taken with extreme care as acute liver toxicity has been reported in a number of cases. Please consult with your herbalist before applying.
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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Fish oil and flax seed oil supplemented diets increase FFAR4 expression in the rat colon by Cheshmehkani A#1, Senatorov IS#1, Kandi P1, Singh M1, Britt A1, Hayslett R1, Moniri NH(PubMed)
(2) Use of defatted flaxseed meal reduces precancerous colon lesions in C57BL/6 mice by Gomides AF1, Paula SO, Rosa DD, Oliveira LL, Comastri DS, Peluzio Mdo C(PubMed)
(3) Flaxseed (Linum usitatissimum L.) and its total non-digestible fraction influence the expression of genes involved in azoxymethane-induced colon cancer in rats by Hernández-Salazar M1, Guevara-González RG, Cruz-Hernández A, Guevara-Olvera L, Bello-Pérez LA, Castaño-Tostado E, Loarca-Piña G(PubMed).
(4) Interactions Between Diet and the Intestinal Microbiota Alter Intestinal Permeability and Colitis Severity in Mice by Llewellyn SR1, Britton GJ1, Contijoch EJ1, Vennaro OH1, Mortha A2, Colombel JF3, Grinspan A3, Clemente JC1, Merad M4, Faith JJ(PubMed)
(5) Fiber and functional gastrointestinal disorders by Eswaran S1, Muir J, Chey WD(PubMed)
(6) Bentonite Clay as a Natural Remedy: A Brief Review by Maryam MOOSAVI(PMC)
(7) Buckthorn Bark, Whole Health Chicago
(8) Permeation-enhancing effect of aloe-emodin anthrone on water-soluble and poorly permeable compounds in rat colonic mucosa by Kai M1, Hayashi K, Kaida I, Aki H, Yamamoto M(PubMed)
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