The Pungent Spice That Inhibits Breast Cancer Cells, Scientists Reveal

The finding of whole food medication by scientists all over the world to replace the single ingredient of the Western medicine for treatment of breast cancer with little or no side effect has been difficult due to no commercial benefits and patent right to producers.

Breast cancer is a medical and chronic condition characterized by irregular cells growth in the breast tissue.

In most cases, breast cancer (malignant breast neoplasm) starts in the tissues of the breast either from the inner lining of milk ducts (Ductal carcinoma) or the lobules (Lobular carcinoma) that supply the ducts with milk.

There are also rare cases that breast cancer starts in other areas of the breast.

According to statistic, in 2010, over 250,000 new cases of breast cancer were expected to be diagnosed in women in the U.S. alone and the risk of getting invasive breast cancer during the lifetime of a woman is 1/8.

Depending to the stage of cancer, women in the very early stage (increased risk of breast cancer) may only experience rusting at the nipple, bloody nipple drainage, a retracted, flattened nipple, particularly in those symptoms that do not go away in 2 weeks.


In the early stage of breast cancer, the tumor is smaller than the approximate size of a peanut (2 centimeters or smaller) and localized.

The survival rate of women diagnosed at this early stage is 100%.

In the breast cancer stage, according to the American Cancer Society, any of the following unusual changes in the breast can be a symptom of breast cancer such as swelling of all or part of the breast, skin irritation or dimpling. breast pain, nipple pain or the nipple turning inward. redness, scaliness, or thickening of the nipple or breast skin.

Therefore, regardless of breast cancer risk, self-examination is one of the best method to detect early breast cancer. All woman should be herself looking at and feeling each breast for possible lumps, distortions or swelling monthly,

Some researchers suggested that women with alternated genes and family history of breast cancers might be required to have their mammogram taken annually.


Garlic (Allium sativum) is a species in the onion genus, belonging to family Amaryllidaceae, native to central Asia.

The food or herb has been used popularly in traditional and Chinese medicine in treating common cold and flu to the Plague, blood pressure cholesterol levels, natural antibiotic, etc.

According to the study, administration of fresh Garlic Extract only exerted a significant effect in the inhibited colon and gastric cancer, but also stimulated cancer cell cycle arrest and alternated the morphology of MCF7 breast cancer cells.

In MCF7 human breast cancer cells, garlic constituent diallyl trisulfide have highly effective antitumor effects by suppressing viability of cultured MCF-7 and MCF-12a cells, through decreased the percent of cells in G(2)/M and induced apoptotic cell death.

According to the study by 201 South University Street, diallyl trisulfide, inhibited the expression of MDA-MB-231 and MCF-7 breast cancer cells, regardless of the state of estrogen in the tumors.

In a total of in 285 women (aged 25-65 years old) newly diagnosed with histopathologically confirmed breast cancer, dietary Allium Vegetables has a negative association between the consumption of raw onion and risk of breast cancer.


Dr. Roy N., the lead author at the Kerala Agricultural University, said, "Docking studies and ADMET evaluation revealed twelve compounds (isolated from garlic) to be active against the targets(breast cancer cell lines). All the compounds displayed highly negative dock scores which indicated good interactions".

These results suggested that the effectiveness of garlic in reduced risk and treatment of breast cancer is probably due to the existence of many phytochemicals found in the herb.

Adding garlic intake to your daily diet can ameliorate the risk of breast cancer substantially.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.


Sources
(1) Fresh Garlic Extract Induces Growth Arrest and Morphological Differentiation of MCF7 Breast Cancer Cells by Modem S1, Dicarlo SE, Reddy TR. (PubMed)
(2) Garlic constituent diallyl trisulfide induced apoptosis in MCF7 human breast cancer cells by Malki A1, El-Saadani M, Sultan AS.(PubMed)
(3) Diallyl trisulfide, a chemopreventive agent from Allium vegetables, inhibits alpha-secretases in breast cancer cells by Kiesel VA1, Stan SD2. (PubMed)