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Sunday, November 18, 2018

Lifelong Use of 8 Types of Conventional Drugs May Cause Cognitive Dysfunction(Dementia and Dementia Like Symptoms) as We Age, Researchers Revealed


About 5-8% of all people over the age of 65 have some form of dementia, and this number doubles every 5 years.

Dementia is the loss of mental and physical ability that is severe enough to interfere with people's daily life and Alzheimer's disease is the most common type of dementia in the aging population.

The western diet contains a high amount of saturated and trans fat, artificial ingredients with fewer fruits and vegetable that can lead to dementia and other kinds of diseases

Types of medication Can Cause Dementia or Dementia Like Symptoms
As the aging progress, accumulation of toxins of certain medication used to treat certain diseases, such as antidepressants, sedatives, cardiovascular drugs, and anti-anxiety medications may induce the increased risk of cognitive dysfunction, leading to dementia and dementia-like symptoms(1).

1. Antidepressants, (selective serotonin reuptake inhibitors, antipsychotics, and benzodiazepines)
An Antidepressant is a psychiatric medication used to treat mood disorders, such as major depression and dysthymia and anxiety disorders.

In a study conducted by Johns Hopkins Bayview Medical Center of total of 230 participants followed for a mean of 3.7 years with use of persistency index (PI) to calculate all antidepressants, selective serotonin reuptake inhibitors (SSRIs), antipsychotics (atypical and typical), and benzodiazepines as the proportion of observed time of medication exposure, researchers found that psychotropic medication used is associated with more rapid cognitive and functional decline in AD, expressed by symptoms scale.

Clinicians may tend to prescribe psychotropic medications to AD patients at risk of poorer outcomes, but one cannot rule out the possibility of poorer outcomes being caused by psychotropic medications(2)

2. Anti-inflammatory drugs (NSAIDs)
Nonsteroidal anti-inflammatory drugs (NSAIDs) are a pain reliever, used often to treat pain caused by overexpression of inflammatory cytokines, such as arthritis.

There was a weak association between any NSAIDs and the risk of cognitively impaired, no dementia (CIND)(3)

3. Cannabis
Cannabis has been used for the treatment of a number of conditions, including neuropathic pain, spasticity associated with multiple sclerosis, and chemotherapy-induced nausea, etc,.

The study conducted by the University of Western Australia showed that chronic use of cannabis may impair intellectual abilities but data on this topic remain sparse and difficult to interpret.

There is evidence that some drugs contribute to the causal pathway that leads to the development of cognitive impairment but currently available data do not support the introduction of a separate diagnostic category of drug-induced dementia (such as alcohol-related dementia)(4).

4. Hallucinogens
Hallucinogens, psychedelic drugs, used primary action to alter cognition and perception may cause distortion of sensory perception, and other psychic and somatic effects, including sweating, heart palpitations, blurring of vision, memory loss, trembling, and itching(5)

5. Corticosteroids
Corticosteroids are synthetic drugs closely resemble cortisol, a steroid hormone produced by the adrenal glands to assist the physiologic processes, including stress response, immune response, and regulation of inflammation, carbohydrate metabolism, behavior, etc.

An excess can cause agitation and even dementia-like symptoms(6).

6. Fluoroquinolone antibiotics
Fluoroquinolone antibiotics is medication taken to treat a variety of infections.
However, the drugs are associated to exhibit delirium in elderly patients(7).

7. H2-receptor antagonists
H2-receptor antagonists are medicines taken to reduce the amount of acid in the stomach by blocking one important producer of histamine2. These drugs are associated to induce delirium in elderly patients(8).

8. Anticonvulsants
Anticonvulsants are types of medication used to treat epileptic seizure act on the brain through different mechanisms. Intake of anticonvulsants can precipitate drowsiness and difficulty thinking, some more common than others(9).

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blog, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
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