Coffee and Coffee Caffeine In Reduced Risk and Progression of Multiple Sclerosis

Good news for coffee loves, high consumption of coffee is associated with decreased risk and progression of Multiple Sclerosis through neuroprotective properties of caffeine, a recent study suggested.

Coffee, second to green tea is one of most popular and social beverage all over the world, particularly in the West, made from roasted bean from the Coffea plant, native to tropical Africa and Madagascar.

Multiple sclerosis (MS) is a neuro disease associated with the brain and spinal cord (central nervous system), caused by immune system attacks the protective sheath.

According to the Swedish study comprising 1620 cases and 2788 controls, and a US study comprising 1159 cases and 1172 controls), participants with different habits of coffee consumption based on retrospective data collection, returned questionnaire from participants showed a significant reduced risk of MS developing for those consuming coffee exceeding 900 mL daily with a relative odd ratio of 0.69 in the Swedish study.


The risk of MS reduced was correlated to cups of coffee consumed daily, regardless to coffee consuming duration prior to disease onset. For every additional intake, the risk of MS is decreased proportionally.


In the animal model, researchers found that the efficacy of coffee in the attenuated risk of MS developing may be attributed to the presence of ingredient of caffeine activity in suppressed production of proinflammatory cytokines.



Additionally, in the investigated of a cross-sectional survey amongst 1372 individuals with MS, registered by the Flemish MS society in Belgium, coffee drinkers showed an improvement of the walk for a distance of 100 m with a cane observed by the Expanded Disability Status Scale (EDSS), compared to those who never consumed coffee.

Dr. D'hooghe MB, the lead author said, "Consumption of...... coffee .......were inversely associated with progression of disability in relapsing onset MS, but not in progressive onset MS".

Other, in a study of dietary intake of 75 women with relapsing/remitting MS (RRMS) and 75 healthy controls conducted by the Shefa Neuroscience Research Center, to support coffee caffeine in reduced risk of MS proposed that food frequency questionnaire consisting of 168 food items returned by participants expressed a significant inverse relationship between MS risk and coffee consumption.



The findings reconfirmed that intake of coffee caffeine in high amount, regardless of numbers years of consumption, is associated with a reduced risk of MS developing and ameliorated the progression of the disease.


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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) High consumption of coffee is associated with decreased multiple sclerosis risk; results from two independent studies by Hedström AK1, Mowry EM2, Gianfrancesco MA3, Shao X3, Schaefer CA4, Shen L4, Olsson T5, Barcellos LF3, Alfredsson L1.(PubMed)
(2) Alcohol, coffee, fish, smoking and disease progression in multiple sclerosis by D'hooghe MB1, Haentjens P, Nagels G, De Keyser J.(PubMed)