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Tuesday, August 6, 2019

Coffee and Coffee Caffeine in Reduced Risk and Treatment of impaired fasting glucose



Intake of coffee and coffee caffeine daily and regularly is associated with reduced risk and treatment of abnormal fasting glucose levels, epidemiological studies suggested.

Impaired fasting glucose is a condition characterized by abnormally high blood glucose after a meal and considered as an indication of prediabetes or symptoms of diabetics.

Coffee, a popular and social beverage all over the world, particularly in the West, is a drink made from roasted bean from the Coffea plant, native to tropical Africa and Madagascar.

In a prospective study, 910 adults aged >/=50 years without diabetes at baseline in 1984-1987 followed to 1992-1996, an average of 8 years after the assessment of coffee intake, researchers found that
past and current coffee drinkers not only had a reduced risk of incident diabetes but also improved impaired glucose compared with those who never drank coffee.

In 317 participants who are past or, current coffee drinkers showed a significantly reduced level of fasting blood glucose compared to the baseline.


Based on an oral glucose tolerance test (OGTT), Dr. Smith B, the lead author said, "This study confirms a striking protective effect of caffeinated coffee against incident diabetes".


Interestingly, in a study comprised 7949 healthy Swedish subjects aged 35-56 years residing within five municipalities of Stockholm. An oral glucose tolerance test identified 55 men and 52 women with previously undiagnosed type 2 diabetes and 172 men and 167 women with impaired glucose tolerance, researchers at the Karolinska Institutet, file the following results
1. The relative risks when drinking >/=5 cups of coffee per day compared with </=2 cups per day in men were 0.45 and 0.63, respectively, and after adjustment of type 2 diabetes and impaired glucose tolerance but in women, the relative risk was reduced substantially to 0.27.

2. Coffee and coffee caffeine intake was associated with inversely in patients with type 2 diabetes.
3. Women, but not in men, with impaired glucose tolerance, also benefit from the improvement of beta-cell function
4. Both gender with normal glucose tolerance, coffee consumption also displayed a strong effect in reduced risk of insulin resistance.



Dr. Agardh EE, the led author said, "high consumers of coffee have a reduced risk of type 2 diabetes and impaired glucose tolerance. The beneficial effects may involve both improved insulin sensitivity and enhanced insulin response".


Additionally, in a study of subsample of subjects aged 45 to 64 years in 1987 and in 1992 from the population-based FINRISK study (12,287 individuals) invited to receive the standard oral glucose tolerance test at baseline, the fasting and two-hour plasma glucose and insulin measured in 2434 subjects, researchers postulated that according to the data, coffee demonstrated a significantly and inversely associated with fasting glucose, two-hour plasma glucose, and fasting insulin in both men and women.

In fact, intake of coffee in the sample also showed a profound effect in ameliorated impaired fasting glucose, improved impaired glucose regulation, and hyperinsulinemia in both gender, particularly in several glycemia markers.


Conclusively, Coffee, not only is a source of chemical compounds such as chlorogenic acids and lignans in improved glucose metabolism but also may be considered as a novel mechanisms for effects of diet on Reduced Risk and Treatment of impaired fasting glucose and prevent the development of type 2 diabetes.




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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Coffee consumption, type 2 diabetes and impaired glucose tolerance in Swedish men and women by Agardh EE1, Carlsson S, Ahlbom A, Efendic S, Grill V, Hammar N, Hilding A, Ostenson CG.(PubMed)
(2) Effects of coffee consumption on glucose tolerance, serum glucose and insulin levels--a cross-sectional analysis by Bidel S1, Hu G, Sundvall J, Kaprio J, Tuomilehto J.(PubMed)
(3) Coffee and type 2 diabetes: from beans to beta-cells by van Dam RM1.(PubMed)

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