The women's breasts are made up of specialized tissue that produces milk (glandular tissue) and fatty tissue. The size of a women's breast is totally determined by the amount of fat.
Breast cancer (malignant breast neoplasm) is cancer that starts in the tissues of the breast either from the inner lining of milk ducts (Ductal carcinoma) or the lobules (Lobular carcinoma) that supply the ducts with milk. There are also rare cases that breast cancer starts in other areas of the breast.
At the advanced stage, after colonizing the entire breast the adance stage, malignant cancers can travel a distance away to infect other healthy cells and tissue.
The exact causes of breast cancer are unknown.
In 2010, over 250,000 new cases of breast cancer were expected to be diagnosed in women in the U.S. alone and the risk of getting invasive breast cancer during the lifetime of women is 1/8.
Unlike general breast cancer which processes either receptors for estrogen or progesterone and/or receptors with a protein called HER2, triple-negative breast cancer is a form of breast cancer that does not share the aforementioned characteristics.
In other words, triple-negative breast cancer does not have receptors of estrogen or progesterone or genetic preposition.
More importantly, triple-negative breast cancer was found to infect women under the age of 40 and women of African or Asian ancestry in the US, compared to breast cancer in the White.
Particularly, according to the epidemiological study, younger women and in women of African ancestry are susceptible to a higher risk of basal-like triple-negative breast cancers.
Compared to the malignant nature, triple-negative and basal-like breast cancers are highly invasive which can grow and spread quickly to other tissues and organs through lymph and blood.
Also compared to other breast cancers, with decreased risk after 5 years, triple-negative breast cancers have a substantial higher recurrent rate within 5 years after treatment.
Fig is a species of F. Carica, belonging to the family Moraceae. It is a deciduous shrub, native to Southeast Asia. The tree can grow to a height of 33 ft and the fruit can be as large as 2.0 inches.
On finding a natural compound or whole food for the treatment of cancer, researchers investigated the effects of Ficus carica leaves on triple-negative breast cancer MDA-MB-231 cells.
According to the tested differentiation, the application of Ficus carica leaves promoted the gene expressions associated with apoptosis.
Furthermore, Ficus carica leaves also demonstrated significant activity in the induction of S phase cell cycle arrest by changing the expression of cyclin-dependent kinases involved in the cancer cell cycle division.
The cell mobility associated with metastasis. in the cells was also inhibited by the application.
Most importantly, 2 chemical compounds bergapten and psoralen found in the F. Carica leaves also had similar anticancer effects as F. Carica leaf extracts.
Based on the results, researchers wrote, "F. Carica leaves might be a good source to develop drugs for suppressing cancer-cell growth and migration to treat triple-negative breast cancers".
Taken altogether, common fig or fig (Ficus carica) may be considered a remedy for the prevention and treatment of triple-negative breast cancer, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Extracts and components of Ficus carica leaves suppress survival, cell cycle, and migration of triple-negative breast cancer MDA-MB-231 cells by Yu Zhang,1 Youzhong Wan,1,2 Bo Huo,1 Boyuan Li,1 Yue Jin,1 and Xin Hu. (PMC)
Ovarian Cyst Miracle (tm)
Permanently and Naturally, Eliminate All Types of Ovarian Cysts Within 2 Months
Sunday, May 30, 2021
Friday, May 28, 2021
Cruciferous Vegetables Inhibit the Risk of Gastric/Stomach Cancer
Gastric cancer is a medical condition characterized by irregular and uncontrollable cell growth in the stomach.
Most cases of gastric cancer start in the cells on the surface of the inner lining of stomach tissue.
Due to the small size at the early stage, gastric cancer is asymptomatic.
However, at the later stage, after penetrating into the deeper layers of the stomach, the cancer cell may travel a distance away to infect other healthy tissues and organs, leading to secondary metastasis.
Researchers do not know why some people with the same health condition are susceptible to the risk of gastric cancer, while others do not. The exact causes of gastric cancer are also unknown. However, some researchers suggested that Age, diet, and stomach disease, such as can increase the risk of developing gastric cancer.
The most common symptoms of gastric cancer are stomach pain, nausea and vomiting, loss of appetite,... and indigestion. However, common symptoms of unexpected weight loss and stomach ulcers can only be found in gastric cancer while iron-deficiency anemia.
According to the statistics provided by the American Cancer Society, in 2019, approximately, 27,510 cases of stomach cancer will be diagnosed (17,230 in men and 10,280 in women) and 11,140 people will die from gastric cancer (6,800 men and 4,340 women).
Overall, the 5-year survival rate for people with gastric cancer is 31%. Cancer diagnosed at the localized stage have a 5 years survival rate of 67%.
Out of many risk factors associated with the onset of cancer, aging may be one of the major risk factors that cause the disease onset as cancer has been found to have a peak incidence between 50 and 70 years of age.
On finding a potential plant that processes anti-invasive cancer activity researchers examined the relationship between consumption of cruciferous vegetables (CV) in the risk of gastric cancer.
According to the meta-analysis that summarize available evidence from epidemiological studies published reports of CV intake and gastric cancer were identified using MEDLINE (PubMed), EMBASE, and Web of Science databases through to the end of September 2012, including 16 case-control and 6 prospective studies,
* The pooled studies showed a significantly inverse association between CV (relative risk = 0.81; 95% confidence interval, 0.75-0.88) intake and gastric cancer risk, with little heterogeneity (Q = 27.27, P = 0.292, I(2) = 12.0%).
* In a separate analysis, the case-control studies of CV intake yielded significant results compared to the borderline statistical significance of CV intake yielded in the prospective studies.
* Moreover, significant results were consistent for high-quality studies, for North American, European, and Asian studies, for studies on males, and for studies on non-cardia gastric cancer.
Based on the findings, researchers said, "... this meta-analysis provides evidence that high intake of CV was inversely associated with the risk of gastric cancer and non-cardia gastric cancer in humans.
Taken altogether, CV with rich phytochemicals may be considered a functional food for the prevention and treatment of gastric cancer, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Cruciferous vegetable consumption and gastric cancer risk: a meta-analysis of epidemiological studies by Wu QJ1, Yang Y, Wang J, Han LH, Xiang YB. (PubMed)
Monday, May 24, 2021
Field Mustards Kill Lung Cancer Cells in Vitro
Cancer is a class of diseases caused by cell growth and multiplication disorderly and uncontrollably due to the alternation of the DNA.
After colonizing the entire tissues of the specific organ, the oversize tumor cell can travel a distance away from the originated site to invade other healthy tissues, via lymph or blood.
The most advanced stage of cancer may result in the death of the patients.
The lung is a vital organ of the human being, located near the backbone on either side of the heart with functions that inhale oxygen from the air then transport them to the bloodstream to nourish the body cells' need and to exhale carbon dioxide from the bloodstream.
Lung cancer is a condition of the abnormal growth of the cells in the lung tissue. The most common form of primary lung cancer is derived from epithelial cells.
The exact cause of lung cancer is not identified. However, epidemiologically, smoking, second smoke, exposure to certain chemicals, family history, people who have lung disease, and excessive drinking are some prevalent factors associated with lung cancer developing.
Current and past smoking account for most cases of lung cancer. The risk of developing lung cancer is about 23 times higher in male smokers compared to non-smokers, epidemiologically.
The most common glands and organs of lung cancer metastases are adrenal glands, bones, brain, and liver.
According to the statistics provided by the American cancer society, lung cancer accounts for 14% of all new cancers diagnosed in the US. In 2018, there were about 234,030 new cases of lung cancer (121,680 in men and 112,350 in women). Lung cancer also causes the death of 83,550 in men and 70,500 in women in the same year.
On finding a potential plant that processes anti-invasive tumor activity researchers compared the effects of an n-butanol subfraction of B. Rapa L. (BRBS) anti-tumor effect on A549 lung adenocarcinoma cell.
According to the experimental results,
* BRBS treatment in a dose- and time-dependent manner, significantly inhibited the proliferation of A549 cells.
* Furthermore, by activating the increased reactive oxygen species (ROS) production to induce cytotoxic effects, BRBS significantly induced cell cycle arrest and apoptosis in A549 cells.
* Moreover, the inhibition was also found to exhibit cancer cell mitochondrial dysfunction characterized by a reduction in mitochondrial membrane potential and the release of cytochrome c, which promoted caspase-3 and poly(ADP-ribose) polymerase processing.
* Additionally, BRBS significantly suppressed the migration of A549 cells in vitro.
Collectively, scientists wrote, "BRBS inhibited A549 cell proliferation through increased ROS production and the mitochondria-dependent apoptosis pathway. Consequently, BRBS might be a potential candidate for the treatment of lung cancer".
Taken altogether, field mustard may be considered a functional food for the prevention and treatment of lung cancer, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) N-Butanol Subfraction of Brassica Rapa L. Promotes Reactive Oxygen Species Production and Induces Apoptosis of A549 Lung Adenocarcinoma Cells via Mitochondria-Dependent Pathway by Aipire A1, Chen Q2, Cai S3, Li J4, Fu C5, Ying T6, Lu J7, Li J. (PubMed)
After colonizing the entire tissues of the specific organ, the oversize tumor cell can travel a distance away from the originated site to invade other healthy tissues, via lymph or blood.
The most advanced stage of cancer may result in the death of the patients.
The lung is a vital organ of the human being, located near the backbone on either side of the heart with functions that inhale oxygen from the air then transport them to the bloodstream to nourish the body cells' need and to exhale carbon dioxide from the bloodstream.
Lung cancer is a condition of the abnormal growth of the cells in the lung tissue. The most common form of primary lung cancer is derived from epithelial cells.
The exact cause of lung cancer is not identified. However, epidemiologically, smoking, second smoke, exposure to certain chemicals, family history, people who have lung disease, and excessive drinking are some prevalent factors associated with lung cancer developing.
Current and past smoking account for most cases of lung cancer. The risk of developing lung cancer is about 23 times higher in male smokers compared to non-smokers, epidemiologically.
The most common glands and organs of lung cancer metastases are adrenal glands, bones, brain, and liver.
According to the statistics provided by the American cancer society, lung cancer accounts for 14% of all new cancers diagnosed in the US. In 2018, there were about 234,030 new cases of lung cancer (121,680 in men and 112,350 in women). Lung cancer also causes the death of 83,550 in men and 70,500 in women in the same year.
On finding a potential plant that processes anti-invasive tumor activity researchers compared the effects of an n-butanol subfraction of B. Rapa L. (BRBS) anti-tumor effect on A549 lung adenocarcinoma cell.
According to the experimental results,
* BRBS treatment in a dose- and time-dependent manner, significantly inhibited the proliferation of A549 cells.
* Furthermore, by activating the increased reactive oxygen species (ROS) production to induce cytotoxic effects, BRBS significantly induced cell cycle arrest and apoptosis in A549 cells.
* Moreover, the inhibition was also found to exhibit cancer cell mitochondrial dysfunction characterized by a reduction in mitochondrial membrane potential and the release of cytochrome c, which promoted caspase-3 and poly(ADP-ribose) polymerase processing.
* Additionally, BRBS significantly suppressed the migration of A549 cells in vitro.
Collectively, scientists wrote, "BRBS inhibited A549 cell proliferation through increased ROS production and the mitochondria-dependent apoptosis pathway. Consequently, BRBS might be a potential candidate for the treatment of lung cancer".
Taken altogether, field mustard may be considered a functional food for the prevention and treatment of lung cancer, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) N-Butanol Subfraction of Brassica Rapa L. Promotes Reactive Oxygen Species Production and Induces Apoptosis of A549 Lung Adenocarcinoma Cells via Mitochondria-Dependent Pathway by Aipire A1, Chen Q2, Cai S3, Li J4, Fu C5, Ying T6, Lu J7, Li J. (PubMed)
Friday, May 21, 2021
Herbal Devil's claw (Harpagophytum procumbens), the Anti-Inflammatory Remedy
Inflammation is the natural response of the immune system macrophages, the first line of defense in stimulating the production of inflammatory cytokines to protect our body against the infection caused by foreign microorganisms during the acute phase of body damage and injury.
Truly, the main focus of inflammation is to repair damage and injury.
Most cases of infection associated with inflammation are stopped at the acute phase. The wound or injury is slowly recovered.
However, overexpression of inflammatory cytokines in most cases can cause improper healing with scar formation or the death of nearby cells.
Any inflammation that lasts more than 8 weeks is considered chronic inflammation.
Believe it or not, worldwide, 3 of 5 death are results from chronic inflammatory diseases like stroke, chronic respiratory diseases, heart disorders, cancer, obesity, and diabetes.
In the US, chronic inflammatory diseases affect more than 50 million Americans each year.
Diseases associated with low-grade inflammation include diabetes and cardiovascular.
Conventionally, Nonsteroidal anti-inflammatory drugs (NSAIDs) are the most common medical drugs such as aspirin. ibuprofen in reducing inflammation associated with pain-relieving.
On finding a natural ingredient for the prevention and treatment of liver diseases, scientists investigated the prepared an extract of Euphrasia officinalis, a traditional folk medicine, to synthesize gold nanoparticles (EO-AuNPs) anti-inflammatory effects on lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophages.
Devil's claw also known as the wood spider, is a plant of genus Harpagophytum in the family of Pedaliaceae, native to South Africa.
The plant has been used as an herb in traditional and herbal medicine to treat fever, rheumatoid arthritis, skin, gallbladder, pancreas, stomach and kidney conditions, etc.
According to tested analysis, the successful synthesis of AuNPs by E. officinalis showed significant anti-inflammatory activities detected by a model of LPS-induced upregulation of inflammatory mediators and cytokines.
More precisely, AuNPs by E. officinalis inhibited the levels of nitric oxide (NO), nitric oxide synthase (iNOS), tumor necrosis factor-α (TNF-α), IL-1β, and IL-6 in RAW 264.7 cells.
Furthermore, EO-AuNPs exhibited little cytotoxicity in RAW 264.7 cells at 100 µg/mL concentration after 24 hours.
Pretreatment with EO-AuNPs also significantly reduced the phosphorylation and degradation of inhibitor kappa B-alpha and inhibited the nuclear translocation of NF-κB p65 involved the production of pro-inflammatory cytokines.
Additionally, EO-AuNPs suppressed LPS-stimulated inflammation by blocking the activation of JAK/STAT pathway associated with cytokines and growth factors.
Based on the results, researchers suggest, "The synthesized EO-AuNPs showed anti-inflammatory activity in LPS-induced RAW 264.7 cells, suggesting they may be potential candidates for treating inflammatory-mediated diseases".
Taken altogether, Dandelion may be considered an anti-inflammatory remedy, pending the confirmation of the larger sample size and multicenter human study.
Truly, the main focus of inflammation is to repair damage and injury.
Most cases of infection associated with inflammation are stopped at the acute phase. The wound or injury is slowly recovered.
However, overexpression of inflammatory cytokines in most cases can cause improper healing with scar formation or the death of nearby cells.
Any inflammation that lasts more than 8 weeks is considered chronic inflammation.
Believe it or not, worldwide, 3 of 5 death are results from chronic inflammatory diseases like stroke, chronic respiratory diseases, heart disorders, cancer, obesity, and diabetes.
In the US, chronic inflammatory diseases affect more than 50 million Americans each year.
Diseases associated with low-grade inflammation include diabetes and cardiovascular.
Conventionally, Nonsteroidal anti-inflammatory drugs (NSAIDs) are the most common medical drugs such as aspirin. ibuprofen in reducing inflammation associated with pain-relieving.
On finding a natural ingredient for the prevention and treatment of liver diseases, scientists investigated the prepared an extract of Euphrasia officinalis, a traditional folk medicine, to synthesize gold nanoparticles (EO-AuNPs) anti-inflammatory effects on lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophages.
Devil's claw also known as the wood spider, is a plant of genus Harpagophytum in the family of Pedaliaceae, native to South Africa.
The plant has been used as an herb in traditional and herbal medicine to treat fever, rheumatoid arthritis, skin, gallbladder, pancreas, stomach and kidney conditions, etc.
According to tested analysis, the successful synthesis of AuNPs by E. officinalis showed significant anti-inflammatory activities detected by a model of LPS-induced upregulation of inflammatory mediators and cytokines.
More precisely, AuNPs by E. officinalis inhibited the levels of nitric oxide (NO), nitric oxide synthase (iNOS), tumor necrosis factor-α (TNF-α), IL-1β, and IL-6 in RAW 264.7 cells.
Furthermore, EO-AuNPs exhibited little cytotoxicity in RAW 264.7 cells at 100 µg/mL concentration after 24 hours.
Pretreatment with EO-AuNPs also significantly reduced the phosphorylation and degradation of inhibitor kappa B-alpha and inhibited the nuclear translocation of NF-κB p65 involved the production of pro-inflammatory cytokines.
Additionally, EO-AuNPs suppressed LPS-stimulated inflammation by blocking the activation of JAK/STAT pathway associated with cytokines and growth factors.
Based on the results, researchers suggest, "The synthesized EO-AuNPs showed anti-inflammatory activity in LPS-induced RAW 264.7 cells, suggesting they may be potential candidates for treating inflammatory-mediated diseases".
Taken altogether, Dandelion may be considered an anti-inflammatory remedy, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Green synthesis of gold nanoparticles using Euphrasia officinalisleaf extract to inhibit lipopolysaccharide-induced inflammation through NF-κB and JAK/STAT pathways in RAW 264.7 macrophages by Liu Y1, Kim S2, Kim YJ1,2, Perumalsamy H2, Lee S3, Hwang E4, Yi TH. (PubMed)
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Green synthesis of gold nanoparticles using Euphrasia officinalisleaf extract to inhibit lipopolysaccharide-induced inflammation through NF-κB and JAK/STAT pathways in RAW 264.7 macrophages by Liu Y1, Kim S2, Kim YJ1,2, Perumalsamy H2, Lee S3, Hwang E4, Yi TH. (PubMed)
Sunday, May 16, 2021
Lycopene Inhibited the Parameters Associated with Onset of Liver Cancer
The liver is the largest internal organ located in the upper right portion of the abdomen, beneath your diaphragm and above your stomach.
The liver not only plays an essential role that filters the blood from the digestive system but also produces bile to build strong cell membranes, produce vitamin D and steroid hormones.
Furthermore, the liver also aids digestive function to absorb nutrients from food intake, and protect the body against free radicals in the body through its antioxidant capacity.
Liver cancer is chronic a condition characterized by out of controlled growth of hepatocellular cells in the liver due to DNA alternation.
Since the organ is a soft tissue with less nerve, most liver cancer patients are diagnosed in the later stage of cancer.
Liver cancer remains the fifth most common malignancy in men and the eighth in women worldwide. According to the statistic, in the US, approximately, 42,030 new cases of liver cancer will be diagnosed in 2019, including 29,480 in men and 12,550 in women.
Sadly, liver cancer also will cause the death of approximately 31,780 people, including 21,600 men and 10,180 women in 2019. Believe it or not, liver cancer death rates have increased by over 2% per year since 2007
Hepatocellular carcinoma (HCC) is a common form of primary liver cancer.
The grade of liver cancer is depending on the tendency of spreading. Low-grade cancers usually grow more slowly and are less likely to spread while high-grade cancers indicate otherwise.
Out of many risks associated with the onset of liver cancer, some researchers that long-term excessive alcohol drinking may be the culprit which causes the rise of liver cancer in the US.
Linda Carroll wrote on the NBC news." Severe alcohol-related liver disease is on the rise, a new study suggests. Experts say the increase may be due to heavy binge drinking, especially in young adults.
And, "...while there has been little change in the rate of people developing alcoholic fatty liver disease, there appears to be an increase in those who are at greater risk of cirrhosis, liver cancer, and death, according to the study published in JAMA"
Lycopene is a phytochemical in the class of carotenoid, a natural pigment with no vitamin A activity found abundantly in tomatoes and other red fruits and vegetables, such as red carrots, watermelons, and papayas,
Tomatoes provide about 80% of the lycopene in the world's diet. In plants, lycopene protects the host against excessive photodamage and performs various functions in photosynthesis.
On finding a potential compound for the prevention of liver cancer, researchers examined the effects of lycopene extracted from tomatoes (LycT) on N-Nitrosodiethylamine (NDEA)-induced hepatocarcinogenesis.
In a study of female BALB/c mice randomly divided into four groups, the Control, NDEA (200 mg NDEA/kg b.w. given i.p.), LycT (5 mg/kg b.w. given orally on alternate days), and LycT + NDEA group, researchers found that* Lycopene treatment inhibited the uncontrolled proliferation in the liver of NDEA associated with the high expression of cell-proliferation (P ≤ 0.001) in NDEA mice observed by the increased expression of genes (PCNA, Cyclin D1, and p21) associated with tumorigenesis compared to control.
* Furthermore, elevated expression of parameters associated with cancer expression in NDEA mice was also inhibited by the injection of lycopene extract compared to control.
* The aforementioned parameters correlated to the alterations in hepatic ultrastructure in the NDEA group were also inhibited by the lycopene extract.
* Moreover, according to the hepatic electron micrographs, LycT + NDEA group showed also increased macrophages, apoptotic bodies and well-differentiated hepatocellular carcinoma (HCC), compared to undifferentiated HCC observed in the NDEA treated group.
Based on the findings, researchers said, "This study demonstrates that dietary supplementation with LycT has a multidimensional role in preventing HCC development".
Taken altogether, lycopene found in tomato may be considered supplements for the prevention of liver cancer pending on the confirmation of the larger sample size and multicenter human study.
Intake of lycopene in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Dietary Tomato Powder Inhibits High-Fat Diet-Promoted Hepatocellular Carcinomawith Alteration of Gut Microbiota in Mice Lacking Carotenoid Cleavage Enzymes by Xia H#1, Liu C#1, Li CC#1, Fu M2, Takahashi S2, Hu KQ1, Aizawa K1,2, Hiroyuki S2, Wu G3, Zhao L3, Wang XD. (PubMed)
(2) Lycopene modulates cellular proliferation, glycolysis and hepatic ultrastructure during hepatocellular carcinoma by Gupta P1, Bhatia N1, Bansal MP1, Koul A. (PubMed)
(3) Severe alcohol-related liver disease on the rise, study finds by Linda Carroll (NBC News)
The liver not only plays an essential role that filters the blood from the digestive system but also produces bile to build strong cell membranes, produce vitamin D and steroid hormones.
Furthermore, the liver also aids digestive function to absorb nutrients from food intake, and protect the body against free radicals in the body through its antioxidant capacity.
Liver cancer is chronic a condition characterized by out of controlled growth of hepatocellular cells in the liver due to DNA alternation.
Since the organ is a soft tissue with less nerve, most liver cancer patients are diagnosed in the later stage of cancer.
Liver cancer remains the fifth most common malignancy in men and the eighth in women worldwide. According to the statistic, in the US, approximately, 42,030 new cases of liver cancer will be diagnosed in 2019, including 29,480 in men and 12,550 in women.
Sadly, liver cancer also will cause the death of approximately 31,780 people, including 21,600 men and 10,180 women in 2019. Believe it or not, liver cancer death rates have increased by over 2% per year since 2007
Hepatocellular carcinoma (HCC) is a common form of primary liver cancer.
The grade of liver cancer is depending on the tendency of spreading. Low-grade cancers usually grow more slowly and are less likely to spread while high-grade cancers indicate otherwise.
Out of many risks associated with the onset of liver cancer, some researchers that long-term excessive alcohol drinking may be the culprit which causes the rise of liver cancer in the US.
Linda Carroll wrote on the NBC news." Severe alcohol-related liver disease is on the rise, a new study suggests. Experts say the increase may be due to heavy binge drinking, especially in young adults.
And, "...while there has been little change in the rate of people developing alcoholic fatty liver disease, there appears to be an increase in those who are at greater risk of cirrhosis, liver cancer, and death, according to the study published in JAMA"
Lycopene is a phytochemical in the class of carotenoid, a natural pigment with no vitamin A activity found abundantly in tomatoes and other red fruits and vegetables, such as red carrots, watermelons, and papayas,
Tomatoes provide about 80% of the lycopene in the world's diet. In plants, lycopene protects the host against excessive photodamage and performs various functions in photosynthesis.
On finding a potential compound for the prevention of liver cancer, researchers examined the effects of lycopene extracted from tomatoes (LycT) on N-Nitrosodiethylamine (NDEA)-induced hepatocarcinogenesis.
In a study of female BALB/c mice randomly divided into four groups, the Control, NDEA (200 mg NDEA/kg b.w. given i.p.), LycT (5 mg/kg b.w. given orally on alternate days), and LycT + NDEA group, researchers found that* Lycopene treatment inhibited the uncontrolled proliferation in the liver of NDEA associated with the high expression of cell-proliferation (P ≤ 0.001) in NDEA mice observed by the increased expression of genes (PCNA, Cyclin D1, and p21) associated with tumorigenesis compared to control.
* Furthermore, elevated expression of parameters associated with cancer expression in NDEA mice was also inhibited by the injection of lycopene extract compared to control.
* The aforementioned parameters correlated to the alterations in hepatic ultrastructure in the NDEA group were also inhibited by the lycopene extract.
* Moreover, according to the hepatic electron micrographs, LycT + NDEA group showed also increased macrophages, apoptotic bodies and well-differentiated hepatocellular carcinoma (HCC), compared to undifferentiated HCC observed in the NDEA treated group.
Based on the findings, researchers said, "This study demonstrates that dietary supplementation with LycT has a multidimensional role in preventing HCC development".
Taken altogether, lycopene found in tomato may be considered supplements for the prevention of liver cancer pending on the confirmation of the larger sample size and multicenter human study.
Intake of lycopene in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Dietary Tomato Powder Inhibits High-Fat Diet-Promoted Hepatocellular Carcinomawith Alteration of Gut Microbiota in Mice Lacking Carotenoid Cleavage Enzymes by Xia H#1, Liu C#1, Li CC#1, Fu M2, Takahashi S2, Hu KQ1, Aizawa K1,2, Hiroyuki S2, Wu G3, Zhao L3, Wang XD. (PubMed)
(2) Lycopene modulates cellular proliferation, glycolysis and hepatic ultrastructure during hepatocellular carcinoma by Gupta P1, Bhatia N1, Bansal MP1, Koul A. (PubMed)
(3) Severe alcohol-related liver disease on the rise, study finds by Linda Carroll (NBC News)
Saturday, May 15, 2021
Brassica Oleracea Vegetables Kills Colorectal cancer Cells in Vitro
The colon-rectum formed a part of the digestive system is involved in the absorption of water from the small bowel contents and broken down certain materials in the feces into substances of which some of them to be reabsorbed and reused by the body.
Cancer is a class of diseases characterized by irregular cell growth on the body tissue, due to the alternation of cell DNA.
Colorectal cancer is a medical condition caused by cell growth irregularly in the tissue of the colon or rectum due to the alternation of cell's DNA.
According to the statistics provided by the American Cancer Society, in the US, colorectal cancer is the third most common cancer diagnosed in both men and women compared to other types of cancer.
The lifetime risk of colorectal cancer is 1 in 22 (4.49%) for men and 1 in 24 (4.15%) for women.
Approximately, 140,000 cases of colorectal cancer were diagnosed in the US in 2018. Colorectal Cancer also causes the death of over 50, 000 people, representing 8.3% of total cancer death.
Being overweight or obese. smoking, physical inactivity, excessive alcohol drinking, the increase in age, family and personal history, genetic preposition are some of the prevalent risks of the disease.
Overall, the lifetime risk of colorectal cancer developing is 1 in 22 (4.49%) in men and 1 in 24 (4.15%) in women.
On finding a potential wholefood for the treatment of cancer, researchers examined the effect of principle bioactive compounds, isothiocyanates (ITCs) on a colorectal cancer cell line (HT-29).
According to the chemicals analysis, purple cabbage extract showed the highest ITC concentration per gram, fresh weight, followed by black cabbage and Romanesco cauliflower.
ITC at the concentrations of 7.08 microg/mL decreased cancer cell viability by inducing the caspase-3 associated with cell death and DNA fragmentation at 48h.
Brussels sprouts showed the strongest effects on cell viability and caspase-3 activity.
Furthermore, all varieties of Brassica Oleracea with rich sources of ITCs potently inhibit the growth of colon cancer cells by inducing apoptosis.
All the extracts showed anticancer activity at ITC concentrations of between 3.54 to 7.08 mug/mL,
Based on the finding, researchers said, " ITC concentration and the chemopreventive responses of plant extracts vary among the varieties of Brassica Oleracea studied and among their cultivars".
Taken altogether, Brassica Oleracea vegetables may be considered functional foods for the prevention and treatment of colorectal cancer, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Induction of apoptosis in HT-29 cells by extracts from isothiocyanates-rich varieties of Brassica oleracea by Mas S1, Crescenti A, Gassó P, Deulofeu R, Molina R, Ballesta A, Kensler TW, Lafuente A. (PubMed)
Cancer is a class of diseases characterized by irregular cell growth on the body tissue, due to the alternation of cell DNA.
Colorectal cancer is a medical condition caused by cell growth irregularly in the tissue of the colon or rectum due to the alternation of cell's DNA.
According to the statistics provided by the American Cancer Society, in the US, colorectal cancer is the third most common cancer diagnosed in both men and women compared to other types of cancer.
The lifetime risk of colorectal cancer is 1 in 22 (4.49%) for men and 1 in 24 (4.15%) for women.
Approximately, 140,000 cases of colorectal cancer were diagnosed in the US in 2018. Colorectal Cancer also causes the death of over 50, 000 people, representing 8.3% of total cancer death.
Being overweight or obese. smoking, physical inactivity, excessive alcohol drinking, the increase in age, family and personal history, genetic preposition are some of the prevalent risks of the disease.
Overall, the lifetime risk of colorectal cancer developing is 1 in 22 (4.49%) in men and 1 in 24 (4.15%) in women.
On finding a potential wholefood for the treatment of cancer, researchers examined the effect of principle bioactive compounds, isothiocyanates (ITCs) on a colorectal cancer cell line (HT-29).
According to the chemicals analysis, purple cabbage extract showed the highest ITC concentration per gram, fresh weight, followed by black cabbage and Romanesco cauliflower.
ITC at the concentrations of 7.08 microg/mL decreased cancer cell viability by inducing the caspase-3 associated with cell death and DNA fragmentation at 48h.
Brussels sprouts showed the strongest effects on cell viability and caspase-3 activity.
Furthermore, all varieties of Brassica Oleracea with rich sources of ITCs potently inhibit the growth of colon cancer cells by inducing apoptosis.
All the extracts showed anticancer activity at ITC concentrations of between 3.54 to 7.08 mug/mL,
Based on the finding, researchers said, " ITC concentration and the chemopreventive responses of plant extracts vary among the varieties of Brassica Oleracea studied and among their cultivars".
Taken altogether, Brassica Oleracea vegetables may be considered functional foods for the prevention and treatment of colorectal cancer, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Induction of apoptosis in HT-29 cells by extracts from isothiocyanates-rich varieties of Brassica oleracea by Mas S1, Crescenti A, Gassó P, Deulofeu R, Molina R, Ballesta A, Kensler TW, Lafuente A. (PubMed)
Friday, May 14, 2021
Omega-3 Fatty Acid Demonstrates a Neuro-Protective Effect in Vivo
The brain formed part of the central nervous system is the most complex organ made up of more than billions of nerve cells or neurons.
The functions of the brain are associated with the communication of trillions of connections called synapses in many specialized regions.
A neuron or nerve cell formed part of the central nervous system, made of a cell body (also called soma), dendrites, and an axon is a cell in the nervous system that carries electrical impulses.
Neurons are core components of the brain, spinal cord, and peripheral nerves that play an essential role in the process and transmit information.
Neurological diseases are the medical conditions of brain disorders. Anything that involves the structural, biochemical or electrical abnormalities in the brain, spinal cord or other nerves, including brain damage are considered as neuro diseases.
The most common neurodegenerative diseases in the elderly are dementia. Depending on the brain regions that are damaged or dysfunctional, dementia can be Parkinson's, Alzheimer's, and Huntington's disease.
Genetic mutation inherited from parents such as the NOTCH3 gene is the most common autosomal dominant inherited cause of stroke and vascular dementia.
Poor lifestyle choices, such as smoking, overuse of alcohol, lack of physical activity and inadequate relief of chronic stress, and poor diet with high in saturated and trans fat, red meat, processed foods, and less in fruits and vegetable and whole-grain are some of the key contributors in the development and progression of chronic diseases, including neurological diseases.
Neuroprotection is a process to preserve the neuronal structure and/or function against the death or gradual death of neurons, including the use of medicines and herbs.
In other words, neuroprotection protects the neuronal integrity against the reduction in the rate of neuronal loss over time inducing neurological disease, including neurodegenerative disease.
Omega-3 fatty acids are phytochemicals in the class of lipids, found abundantly in deepsea fisk, dark-green leafy vegetables, grains, legumes, nuts, etc.
The three main components of Omega-3 fatty acids are alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).
On finding a potential phytochemical for the treatment of neuro-diseases, researchers examined the effects of omega-3 polyunsaturated fatty acids (ω-3 PUFAs) on alleviating microinfarct burdens and functional deficits.
According to the results of Fat-1 transgenic mice and fish oil supplements, ω-3 PUFAs showed strong protective activity against microinfarcts in a multiple diffuse microinfarcts model.
In other words, ω-3 PUFAs significantly attenuated cell apoptosis.
Furthermore, ω-3 PUFAs alleviated the diffuse microinfarct burdens and remarkably improved the functional deficits by reducing spontaneous anxiety, increased preference for the novel object, and improved hippocampal-based learning and short-term memory.
Collectively, researchers said, " enriched brain ω-3 PUFAs are effective for reducing microinfarct burdens and improving the function deficits, which support the clinical research and application of ω-3 PUFAs in the treatment or prophylaxis in vascular dementia".
Taken altogether, Omega-3 fatty acids found abundantly in fish oil and plant oil may be considered a neuro-protective functional food, pending the confirmation of the larger sample size and multicenter human study.
Intake of Omega-3 fatty acids in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Enriched Brain Omega-3 Polyunsaturated Fatty Acids Confer Neuroprotection against Microinfarction by Luo C1, Ren H2, Yao X3, Shi Z2, Liang F3, Kang JX4, Wan JB2, Pei Z3, Su KP5, Su H. (PubMed)
(2) Enriched Brain Omega-3 Polyunsaturated Fatty Acids Confer Neuroprotection against Microinfarction by Luo C1, Ren H2, Yao X3, Shi Z2, Liang F3, Kang JX4, Wan JB2, Pei Z3, Su KP5, Su H. (PubMed)
The functions of the brain are associated with the communication of trillions of connections called synapses in many specialized regions.
A neuron or nerve cell formed part of the central nervous system, made of a cell body (also called soma), dendrites, and an axon is a cell in the nervous system that carries electrical impulses.
Neurons are core components of the brain, spinal cord, and peripheral nerves that play an essential role in the process and transmit information.
Neurological diseases are the medical conditions of brain disorders. Anything that involves the structural, biochemical or electrical abnormalities in the brain, spinal cord or other nerves, including brain damage are considered as neuro diseases.
The most common neurodegenerative diseases in the elderly are dementia. Depending on the brain regions that are damaged or dysfunctional, dementia can be Parkinson's, Alzheimer's, and Huntington's disease.
Genetic mutation inherited from parents such as the NOTCH3 gene is the most common autosomal dominant inherited cause of stroke and vascular dementia.
Poor lifestyle choices, such as smoking, overuse of alcohol, lack of physical activity and inadequate relief of chronic stress, and poor diet with high in saturated and trans fat, red meat, processed foods, and less in fruits and vegetable and whole-grain are some of the key contributors in the development and progression of chronic diseases, including neurological diseases.
Neuroprotection is a process to preserve the neuronal structure and/or function against the death or gradual death of neurons, including the use of medicines and herbs.
In other words, neuroprotection protects the neuronal integrity against the reduction in the rate of neuronal loss over time inducing neurological disease, including neurodegenerative disease.
Omega-3 fatty acids are phytochemicals in the class of lipids, found abundantly in deepsea fisk, dark-green leafy vegetables, grains, legumes, nuts, etc.
The three main components of Omega-3 fatty acids are alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).
On finding a potential phytochemical for the treatment of neuro-diseases, researchers examined the effects of omega-3 polyunsaturated fatty acids (ω-3 PUFAs) on alleviating microinfarct burdens and functional deficits.
According to the results of Fat-1 transgenic mice and fish oil supplements, ω-3 PUFAs showed strong protective activity against microinfarcts in a multiple diffuse microinfarcts model.
In other words, ω-3 PUFAs significantly attenuated cell apoptosis.
Furthermore, ω-3 PUFAs alleviated the diffuse microinfarct burdens and remarkably improved the functional deficits by reducing spontaneous anxiety, increased preference for the novel object, and improved hippocampal-based learning and short-term memory.
Collectively, researchers said, " enriched brain ω-3 PUFAs are effective for reducing microinfarct burdens and improving the function deficits, which support the clinical research and application of ω-3 PUFAs in the treatment or prophylaxis in vascular dementia".
Taken altogether, Omega-3 fatty acids found abundantly in fish oil and plant oil may be considered a neuro-protective functional food, pending the confirmation of the larger sample size and multicenter human study.
Intake of Omega-3 fatty acids in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Enriched Brain Omega-3 Polyunsaturated Fatty Acids Confer Neuroprotection against Microinfarction by Luo C1, Ren H2, Yao X3, Shi Z2, Liang F3, Kang JX4, Wan JB2, Pei Z3, Su KP5, Su H. (PubMed)
(2) Enriched Brain Omega-3 Polyunsaturated Fatty Acids Confer Neuroprotection against Microinfarction by Luo C1, Ren H2, Yao X3, Shi Z2, Liang F3, Kang JX4, Wan JB2, Pei Z3, Su KP5, Su H. (PubMed)
Monday, May 10, 2021
Tocopherols Inhibits the Onset of Colorectal Cancer in Men ONLY
The colon-rectum formed a part of the digestive system is involved in the absorption of water from the small bowel contents and broken down of certain materials in the feces and into substances of which some of them to be reabsorbed and reused by the body.
Colorectal cancer is a medical condition caused by cell growth irregularly in the tissue of the colon or rectum due to the alternation of cells' DNA.
Colorectal cancer is relatively very common and slowly growing and progressing cancer.
The disease is also the third most commonly diagnosed cancer in developed countries, including the US and Canada.
According to the statistics provided by the American Cancer Society, in the US, colorectal cancer is the third most common cancer diagnosed in both men and women compared to other types of cancer.
The lifetime risk of colorectal cancer is 1 in 22 (4.49%) for men and 1 in 24 (4.15%) for women.
Approximately, 140,000 cases of colorectal cancer were diagnosed in the US in 2018. Cancer also causes the death of over 50, 000 people, representing 8.3% of total cancer death.
Being overweight or obese. smoking, physical inactivity, excessive alcohol drinking, the increase in age, family and personal history, genetic preposition are some of the prevalent risks of the disease.
Tocopherols are phytochemicals of which many have vitamin E activity, belonging to the group of Lipids, found abundantly in butter, egg yolk, milk fat, some vegetable, and seed or nut oils, etc.
On finding a potential phytochemical for the treatment of cancers, researchers examined the associations of serum carotenoids, retinol, and tocopherols with colorectal cancer risk.
According to the case-control study nested within the Japan Collaborative Cohort Study, including micronutrients measured in prediagnostic serum samples from 116 men and women who developed colorectal cancer during an 8-yr follow-up period and from 298 matched controls,* In men, the higher level of serum total carotenoids was associated with a decreased risk with the multivariate-adjusted odds ratio (OR) for the highest vs. the lowest tertile of 0.34.
* The increased serum retinol in all subjects and alpha-tocopherol also associated with a decreasing risk of cancer with the ORs for the highest tertiles were 0.29 and 0.29, respectively.
* In women, the higher levels of alpha- and total carotenoids were instead related to increased risk: with the corresponding ORs of 4.72 (95% CI = 1.29-17.3), 2.00 (0.70-5.73), and 2.47 (0.73-8.34), respectively.
Taken altogether, tocopherols may be considered a supplement for the treatment of colorectal cancer in MEN only, pending the confirmation of the larger sample size and multicenter human study.
Intake of tocopherols in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Serum carotenoids, retinol, and tocopherols, and colorectal cancer risk in a Japanese cohort: effect modification by sex for carotenoids by Wakai K1, Suzuki K, Ito Y, Kojima M, Tamakoshi K, Watanabe Y, Toyoshima H, Hayakawa N, Hashimoto S, Tokudome S, Suzuki S, Kawado M, Ozasa K, Tamakoshi A; Japan Collaborative Cohort Study Group. (PubMed)
Colorectal cancer is a medical condition caused by cell growth irregularly in the tissue of the colon or rectum due to the alternation of cells' DNA.
Colorectal cancer is relatively very common and slowly growing and progressing cancer.
The disease is also the third most commonly diagnosed cancer in developed countries, including the US and Canada.
According to the statistics provided by the American Cancer Society, in the US, colorectal cancer is the third most common cancer diagnosed in both men and women compared to other types of cancer.
The lifetime risk of colorectal cancer is 1 in 22 (4.49%) for men and 1 in 24 (4.15%) for women.
Approximately, 140,000 cases of colorectal cancer were diagnosed in the US in 2018. Cancer also causes the death of over 50, 000 people, representing 8.3% of total cancer death.
Being overweight or obese. smoking, physical inactivity, excessive alcohol drinking, the increase in age, family and personal history, genetic preposition are some of the prevalent risks of the disease.
Tocopherols are phytochemicals of which many have vitamin E activity, belonging to the group of Lipids, found abundantly in butter, egg yolk, milk fat, some vegetable, and seed or nut oils, etc.
On finding a potential phytochemical for the treatment of cancers, researchers examined the associations of serum carotenoids, retinol, and tocopherols with colorectal cancer risk.
According to the case-control study nested within the Japan Collaborative Cohort Study, including micronutrients measured in prediagnostic serum samples from 116 men and women who developed colorectal cancer during an 8-yr follow-up period and from 298 matched controls,* In men, the higher level of serum total carotenoids was associated with a decreased risk with the multivariate-adjusted odds ratio (OR) for the highest vs. the lowest tertile of 0.34.
* The increased serum retinol in all subjects and alpha-tocopherol also associated with a decreasing risk of cancer with the ORs for the highest tertiles were 0.29 and 0.29, respectively.
* In women, the higher levels of alpha- and total carotenoids were instead related to increased risk: with the corresponding ORs of 4.72 (95% CI = 1.29-17.3), 2.00 (0.70-5.73), and 2.47 (0.73-8.34), respectively.
Taken altogether, tocopherols may be considered a supplement for the treatment of colorectal cancer in MEN only, pending the confirmation of the larger sample size and multicenter human study.
Intake of tocopherols in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Serum carotenoids, retinol, and tocopherols, and colorectal cancer risk in a Japanese cohort: effect modification by sex for carotenoids by Wakai K1, Suzuki K, Ito Y, Kojima M, Tamakoshi K, Watanabe Y, Toyoshima H, Hayakawa N, Hashimoto S, Tokudome S, Suzuki S, Kawado M, Ozasa K, Tamakoshi A; Japan Collaborative Cohort Study Group. (PubMed)
Saturday, May 8, 2021
Green Peas (Pisum Sativum), the Potential Anti Colitis Health Food
Inflammatory bowel disease (IBD) refers to a set of disorders that involve chronic inflammation of your digestive tract, including the most common types such as
* Ulcerative colitis affects the innermost lining of your large intestine (colon) and rectum.
* Crohn's disease affects mostly the colon and the last part of the small intestine (ileum).
Colitis is a condition of inflammation of the large intestine, including the colon, caecum, and rectum.
There is no exact cause of colitis. Certain risk factors such as colon infection, inflammatory bowel disease (Crohn's disease, ulcerative colitis), ischemic colitis, allergic reactions, and microscopic colitis have been found to increase the risk of the condition.
The most common symptoms of colitis are totally depending on the types, including abdominal pain, cramping, diarrhea, with or without blood in the stool.
Conventionally, colitis caused by infection is treated by antibiotics. However, treatment of non-infection colitis is focusing on symptom relief, supportive care, and maintaining adequate hydration and pain control.
The most common tools used for the colitis diagnosis are X-rays of the colon, testing the stool for blood and pus, sigmoidoscopy, and colonoscopy.
The statistics provided by a study from the Medscape, suggested, "Internationally, the incidence of IBD is approximately 0.5-24.5 cases per 100,000 person-years for ulcerative colitis and 0.1-16 cases per 100,000 person-years for Crohn disease. Overall, the prevalence of IBD is 396 cases per 100,000 persons annually".
Green peas are species of Pisum Sativum belongings to the family Fabaceae and native to western Asia from the Mediterranean Sea to the Himalaya Mountains. The pea is a green, pod-shaped vegetable and a cool-season crop grown in many parts of the world.
On finding a potent ingredient for the treatment of diseases associated with colonic inflammation, researchers investigated the impact of green pea (GP) supplementation on the susceptibility of high-fat diet (HFD)-fed mice to dextran sulfate sodium (DSS)-induced colitis.
The study included 6-week-old C57BL/6J female mice induced colitis was induced by adding 2.5% DSS in drinking water for 7 days followed by a 7-day recovery period that was fed a 45% HFD or HFD supplemented with 10% GP, after 7-week dietary supplementation.
According to the tested analysis, the administration of GP supplementation ameliorated the disease activity index score in HFD-fed mice during the recovery stage, and reduced neutrophil infiltration-associated immune responses.
Furthermore, the production of pro-inflammatory cytokines involved in the mRNA expression of monocyte chemoattractant protein-1 (MCP-1) and inflammatory markers interleukin (IL)-6, cyclooxygenase-2 (COX-2), IL-17, interferon-γ (IFN-γ), and inducible nitric oxide synthase (iNOS) in HFD-fed mice was significantly decreased by the injection of GP.
Moreover, levels of mucin 2 produced from goblet cells in the epithelial lining into the lumen of the large intestine to protect the intestinal epithelium also increased in GP mice.
Additionally, GP ameliorated endoplasmic reticulum (ER) stress involved in the mediation of a pro-inflammatory synergy in the colon.
Based on the results, scientists said, " GP supplementation ameliorated the severity of DSS-induced colitis in HFD-fed mice, which was associated with the suppression of inflammation, mucin depletion, and ER stress in the colon".
Taken altogether, green peas may be considered a functional food for the prevention of colitis, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Dietary Green Pea Protects against DSS-Induced Colitis in Mice Challenged with High-Fat Diet by Shima Bibi, Luís Fernando de Sousa Moraes, Noelle Lebow, and Mei-Jun Zhu. (PMC)
(2) What is the global prevalence of inflammatory bowel disease (IBD)? by William A Rowe, MD; Chief Editor: BS Anand, MD. (Medscape)
* Ulcerative colitis affects the innermost lining of your large intestine (colon) and rectum.
* Crohn's disease affects mostly the colon and the last part of the small intestine (ileum).
Colitis is a condition of inflammation of the large intestine, including the colon, caecum, and rectum.
There is no exact cause of colitis. Certain risk factors such as colon infection, inflammatory bowel disease (Crohn's disease, ulcerative colitis), ischemic colitis, allergic reactions, and microscopic colitis have been found to increase the risk of the condition.
The most common symptoms of colitis are totally depending on the types, including abdominal pain, cramping, diarrhea, with or without blood in the stool.
Conventionally, colitis caused by infection is treated by antibiotics. However, treatment of non-infection colitis is focusing on symptom relief, supportive care, and maintaining adequate hydration and pain control.
The most common tools used for the colitis diagnosis are X-rays of the colon, testing the stool for blood and pus, sigmoidoscopy, and colonoscopy.
The statistics provided by a study from the Medscape, suggested, "Internationally, the incidence of IBD is approximately 0.5-24.5 cases per 100,000 person-years for ulcerative colitis and 0.1-16 cases per 100,000 person-years for Crohn disease. Overall, the prevalence of IBD is 396 cases per 100,000 persons annually".
Green peas are species of Pisum Sativum belongings to the family Fabaceae and native to western Asia from the Mediterranean Sea to the Himalaya Mountains. The pea is a green, pod-shaped vegetable and a cool-season crop grown in many parts of the world.
On finding a potent ingredient for the treatment of diseases associated with colonic inflammation, researchers investigated the impact of green pea (GP) supplementation on the susceptibility of high-fat diet (HFD)-fed mice to dextran sulfate sodium (DSS)-induced colitis.
The study included 6-week-old C57BL/6J female mice induced colitis was induced by adding 2.5% DSS in drinking water for 7 days followed by a 7-day recovery period that was fed a 45% HFD or HFD supplemented with 10% GP, after 7-week dietary supplementation.
According to the tested analysis, the administration of GP supplementation ameliorated the disease activity index score in HFD-fed mice during the recovery stage, and reduced neutrophil infiltration-associated immune responses.
Furthermore, the production of pro-inflammatory cytokines involved in the mRNA expression of monocyte chemoattractant protein-1 (MCP-1) and inflammatory markers interleukin (IL)-6, cyclooxygenase-2 (COX-2), IL-17, interferon-γ (IFN-γ), and inducible nitric oxide synthase (iNOS) in HFD-fed mice was significantly decreased by the injection of GP.
Moreover, levels of mucin 2 produced from goblet cells in the epithelial lining into the lumen of the large intestine to protect the intestinal epithelium also increased in GP mice.
Additionally, GP ameliorated endoplasmic reticulum (ER) stress involved in the mediation of a pro-inflammatory synergy in the colon.
Based on the results, scientists said, " GP supplementation ameliorated the severity of DSS-induced colitis in HFD-fed mice, which was associated with the suppression of inflammation, mucin depletion, and ER stress in the colon".
Taken altogether, green peas may be considered a functional food for the prevention of colitis, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Dietary Green Pea Protects against DSS-Induced Colitis in Mice Challenged with High-Fat Diet by Shima Bibi, Luís Fernando de Sousa Moraes, Noelle Lebow, and Mei-Jun Zhu. (PMC)
(2) What is the global prevalence of inflammatory bowel disease (IBD)? by William A Rowe, MD; Chief Editor: BS Anand, MD. (Medscape)
Wednesday, May 5, 2021
Herbal Angelica May Reduce the Mortality Rate in Patients with Sepsis
Sepsis is a condition caused by chemicals released into the bloodstream to fight the infection that triggers inflammation throughout the body as a result of severe infection(a)(b). according to the study by the University of Utah, sepsis is the commonest cause of admission to medical ICUs across the world.
Mortality from sepsis continues to be high. Besides shock and multi-organ dysfunction occurring following the intense inflammatory reaction to sepsis, complications arising from sepsis-related immunoparalysis contribute to the morbidity and mortality from sepsis(c).
The most common risk factors associated with the prevalent factors of sepsis, term infants, while very low birth weight (VLBW) and preterm infants, obesity, operative vaginal delivery and age <25 years, elderly, patient in intensive care and with weakened immune system, invasive devices, and alcoholism.
Diseases associated with Sepsis are
* Staphylococcal infections
Preterm infants are especially susceptible to late-onset sepsis that is often due to Gram-positive bacterial infections resulting in substantial morbidity and mortality(24).
* Elevated central venous pressure
Elevated central venous pressure is associated with impairment of microcirculatory blood flow in sepsis(25).
* Neonatal cellulitis
There is a report of a case of late-onset neonatal invasive group A streptococcal disease characterized by rapidly progressing cellulitis and development of sepsis(26).
* Methicillin-resistant Staphylococcus aureus
There is a report of the spectrum of community-acquired S. aureus infections and to compare the patients infected with methicillin-susceptible or methicillin-resistant strains among patients aged <20 years. Overall, 90 cases of community-acquired S. aureus were detected in an 11-year period(27).
* Bladder infection
Bladder bacteria is a common but unique cause of sepsis(28).
* Urinary tract infection
In the study to evaluate the effectiveness of Lactobacillus GG supplementation in reducing the incidence of urinary tract infections (UTIs), bacterial sepsis, and necrotizing enterocolitis (NEC) in preterm infants, found that seven days of Lactobacillus GG supplementation starting with the first feed is not effective in reducing the incidence of UTIs, NEC, and sepsis in preterm infants. Further studies are required to confirm our results in lower birth weight populations(29).
On finding a natural ingredient for the prevention and treatment of infectious diseases, scientists examined the effects of Xuebijing injection (XBJ), a Chinese patent medicine on sepsis.
Angelica or Dang Qui is a herb of Genus Angelica from the family Apiaceae, indigenous to China.
The herb has been used as a Queen herb in traditional Chinese medicine antispasmodic and vasodilatory agent, and to balance the hormones in women for a normal menstrual cycle and menstruation and strengthen heart, spleen, kidneys, and liver for both men and women, etc. In other words, it is used to treat gynecological ailments, fatigue, mild anemia, and high blood pressure. It has analgesic, anti-inflammatory, etc.
According to the search of medical literature in Embase, PubMed, the Cochrane Central Register of Controlled Trials, China National Knowledge Infrastructure (CNKI), Chinese Science and Technology Journal Database (VIP), and the Wanfang database from inception to June 6, 2017, including relevant RCTs comparing XBJ combined with RT and RT alone for sepsis, * 1602 records and 16 RCTs (1144 patients) identified suggested that the combined therapy reduced 28-day mortality and body temperature.
* WBC count improved with combined medication at high dosages (one study included, 40/1144, MD -8.00, 95% CI -10.18 to -5.82) with no reduction at moderate dosages.
* However, moderate-quality evidence indicated positive results with low dosages.
Based on the results, researchers suggest, "This study suggested that supplementation with XBJ in addition to regular treatment may improve the 28-day mortality rate, APACHE Ⅱ scores, WBC count, and body temperature of sepsis patients without serious adverse events".
Taken altogether, angelica used combined with other herbal medicines may be considered a remedy for the treatment of sepsis, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Efficacy and safety of Xuebijing injection (a Chinese patent) for sepsis: A meta-analysis of randomized controlled trials by Li C1, Wang P2, Zhang L3, Li M4, Lei X5, Liu S6, Feng Z7, Yao Y8, Chang B9, Liu B10, Shang H. (PubMed)
(2) Thyroid disease: Euthyroid sick syndrome as a result of Sepsis - Diseases associated with Sepsis by Kyle J. Norton
Mortality from sepsis continues to be high. Besides shock and multi-organ dysfunction occurring following the intense inflammatory reaction to sepsis, complications arising from sepsis-related immunoparalysis contribute to the morbidity and mortality from sepsis(c).
The most common risk factors associated with the prevalent factors of sepsis, term infants, while very low birth weight (VLBW) and preterm infants, obesity, operative vaginal delivery and age <25 years, elderly, patient in intensive care and with weakened immune system, invasive devices, and alcoholism.
Diseases associated with Sepsis are
* Staphylococcal infections
Preterm infants are especially susceptible to late-onset sepsis that is often due to Gram-positive bacterial infections resulting in substantial morbidity and mortality(24).
* Elevated central venous pressure
Elevated central venous pressure is associated with impairment of microcirculatory blood flow in sepsis(25).
* Neonatal cellulitis
There is a report of a case of late-onset neonatal invasive group A streptococcal disease characterized by rapidly progressing cellulitis and development of sepsis(26).
* Methicillin-resistant Staphylococcus aureus
There is a report of the spectrum of community-acquired S. aureus infections and to compare the patients infected with methicillin-susceptible or methicillin-resistant strains among patients aged <20 years. Overall, 90 cases of community-acquired S. aureus were detected in an 11-year period(27).
* Bladder infection
Bladder bacteria is a common but unique cause of sepsis(28).
* Urinary tract infection
In the study to evaluate the effectiveness of Lactobacillus GG supplementation in reducing the incidence of urinary tract infections (UTIs), bacterial sepsis, and necrotizing enterocolitis (NEC) in preterm infants, found that seven days of Lactobacillus GG supplementation starting with the first feed is not effective in reducing the incidence of UTIs, NEC, and sepsis in preterm infants. Further studies are required to confirm our results in lower birth weight populations(29).
On finding a natural ingredient for the prevention and treatment of infectious diseases, scientists examined the effects of Xuebijing injection (XBJ), a Chinese patent medicine on sepsis.
Angelica or Dang Qui is a herb of Genus Angelica from the family Apiaceae, indigenous to China.
The herb has been used as a Queen herb in traditional Chinese medicine antispasmodic and vasodilatory agent, and to balance the hormones in women for a normal menstrual cycle and menstruation and strengthen heart, spleen, kidneys, and liver for both men and women, etc. In other words, it is used to treat gynecological ailments, fatigue, mild anemia, and high blood pressure. It has analgesic, anti-inflammatory, etc.
According to the search of medical literature in Embase, PubMed, the Cochrane Central Register of Controlled Trials, China National Knowledge Infrastructure (CNKI), Chinese Science and Technology Journal Database (VIP), and the Wanfang database from inception to June 6, 2017, including relevant RCTs comparing XBJ combined with RT and RT alone for sepsis, * 1602 records and 16 RCTs (1144 patients) identified suggested that the combined therapy reduced 28-day mortality and body temperature.
* WBC count improved with combined medication at high dosages (one study included, 40/1144, MD -8.00, 95% CI -10.18 to -5.82) with no reduction at moderate dosages.
* However, moderate-quality evidence indicated positive results with low dosages.
Based on the results, researchers suggest, "This study suggested that supplementation with XBJ in addition to regular treatment may improve the 28-day mortality rate, APACHE Ⅱ scores, WBC count, and body temperature of sepsis patients without serious adverse events".
Taken altogether, angelica used combined with other herbal medicines may be considered a remedy for the treatment of sepsis, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Efficacy and safety of Xuebijing injection (a Chinese patent) for sepsis: A meta-analysis of randomized controlled trials by Li C1, Wang P2, Zhang L3, Li M4, Lei X5, Liu S6, Feng Z7, Yao Y8, Chang B9, Liu B10, Shang H. (PubMed)
(2) Thyroid disease: Euthyroid sick syndrome as a result of Sepsis - Diseases associated with Sepsis by Kyle J. Norton
Saturday, May 1, 2021
Legumes May Be Considered the Natural Anti-Hypercholesterolemic Functional Foods
Hypercholesterolemia is a condition characterized by abnormally high levels of cholesterol in the bloodstream.
The cause of hypercholesterolemia is a result of overexpression of low-density lipoprotein with reduced levels of high-density lipoprotein in the blood.
In other words, the condition is a result caused by either overexpression of "bad" cholesterol (LDL) or low levels of "good" cholesterol (HDL).
Cholesterol, a waxy substance produced by the liver or the dietary in moderate amount source plays a critical to aid digestive function in absorbing nutrients, build strong cell membranes, produce steroid hormones and vitamin D. However, excessive amounts in the blood have been found to induce plaque built-up on the arterial wall, leading to heart disease and stroke.
Similar to high blood pressure, people with hypercholesterolemia are asymptomatic. Patients with familial hyper cholesterol may experience symptoms of chest pain with activity. xanthomas, and cholesterol deposits around the eyelids.
The most common complications associated with uncontrolled hypercholesterolemia are carotid artery disease, coronary heart disease, including angina or heart attack, peripheral artery disease, and stroke.
According to the statistics provided by the CDC, hypercholesterolemia is a major risk factor of heart disease, a leading cause of death in the US. In the US, approximately, 71 million American adults (33.5%) have high low-density lipoprotein (LDL), or “bad,” cholesterol, and only 1 out of every 3 adults with high LDL cholesterol has the condition under control.
Compared to hypercholesterolemia, the healthy levels of LDL/HDL are any numbers that are less than 4.
There is no single cause of hypercholesterolemia. Epidemiologically, diet, obesity, genetic preposition, and medical conditions such as diseases such as type 2 diabetes and an underactive thyroid are some of the prevalent factors associated with the risk of the condition.
Legume is a class of fruits or seeds of a plant group in the family Fabaceae (or Leguminosae), cultivated all over the world as foods for commercial profits.
On finding a potent ingredient for the treatment of diseases associated with high blood cholesterols, researchers investigated the impact of potential health benefits of legumes as a good source of dietary fiber such as cowpeas, mung beans, pole sitao, chickpeas, green peas, groundnuts, pigeon peas, kidney beans, lima beans and soybeans against hypercholesterolemia.
According to the tested analysis,
* In vitro, the legume showed a good glycaemic index (GI) in non-diabetic and diabetic human subjects.
*The legume exerted a cholesterol-lowering effect in human subjects with moderately raised serum cholesterol levels.
* Kidney beans showed significant reductions for both total (6 %) and LDL-cholesterol (9 %), and groundnuts for total cholesterol (7 %; P < 0.05), compared to other types of legume.
Based on the findings, researchers concluded, "legumes are considered low-GI foods and have shown potential hypocholesterolemic effects. The above studies can be a scientific basis for considering legumes as functional foods".
Taken altogether, legume may be considered a functional food for the prevention of hypercholesterolemia, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) The potential health benefits of legumes as a good source of dietary fibre by Trinidad TP1, Mallillin AC, Loyola AS, Sagum RS, Encabo RR. (PubMed)
The cause of hypercholesterolemia is a result of overexpression of low-density lipoprotein with reduced levels of high-density lipoprotein in the blood.
In other words, the condition is a result caused by either overexpression of "bad" cholesterol (LDL) or low levels of "good" cholesterol (HDL).
Cholesterol, a waxy substance produced by the liver or the dietary in moderate amount source plays a critical to aid digestive function in absorbing nutrients, build strong cell membranes, produce steroid hormones and vitamin D. However, excessive amounts in the blood have been found to induce plaque built-up on the arterial wall, leading to heart disease and stroke.
Similar to high blood pressure, people with hypercholesterolemia are asymptomatic. Patients with familial hyper cholesterol may experience symptoms of chest pain with activity. xanthomas, and cholesterol deposits around the eyelids.
The most common complications associated with uncontrolled hypercholesterolemia are carotid artery disease, coronary heart disease, including angina or heart attack, peripheral artery disease, and stroke.
According to the statistics provided by the CDC, hypercholesterolemia is a major risk factor of heart disease, a leading cause of death in the US. In the US, approximately, 71 million American adults (33.5%) have high low-density lipoprotein (LDL), or “bad,” cholesterol, and only 1 out of every 3 adults with high LDL cholesterol has the condition under control.
Compared to hypercholesterolemia, the healthy levels of LDL/HDL are any numbers that are less than 4.
There is no single cause of hypercholesterolemia. Epidemiologically, diet, obesity, genetic preposition, and medical conditions such as diseases such as type 2 diabetes and an underactive thyroid are some of the prevalent factors associated with the risk of the condition.
Legume is a class of fruits or seeds of a plant group in the family Fabaceae (or Leguminosae), cultivated all over the world as foods for commercial profits.
On finding a potent ingredient for the treatment of diseases associated with high blood cholesterols, researchers investigated the impact of potential health benefits of legumes as a good source of dietary fiber such as cowpeas, mung beans, pole sitao, chickpeas, green peas, groundnuts, pigeon peas, kidney beans, lima beans and soybeans against hypercholesterolemia.
According to the tested analysis,
* In vitro, the legume showed a good glycaemic index (GI) in non-diabetic and diabetic human subjects.
*The legume exerted a cholesterol-lowering effect in human subjects with moderately raised serum cholesterol levels.
* Kidney beans showed significant reductions for both total (6 %) and LDL-cholesterol (9 %), and groundnuts for total cholesterol (7 %; P < 0.05), compared to other types of legume.
Based on the findings, researchers concluded, "legumes are considered low-GI foods and have shown potential hypocholesterolemic effects. The above studies can be a scientific basis for considering legumes as functional foods".
Taken altogether, legume may be considered a functional food for the prevention of hypercholesterolemia, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) The potential health benefits of legumes as a good source of dietary fibre by Trinidad TP1, Mallillin AC, Loyola AS, Sagum RS, Encabo RR. (PubMed)
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