Cruciferous Vegetables Inhibit the Risk of Gastric/Stomach Cancer

Gastric cancer is a medical condition characterized by irregular and uncontrollable cell growth in the stomach.

Most cases of gastric cancer start in the cells on the surface of the inner lining of stomach tissue.
Due to the small size at the early stage, gastric cancer is asymptomatic.

However, at the later stage, after penetrating into the deeper layers of the stomach, the cancer cell may travel a distance away to infect other healthy tissues and organs, leading to secondary metastasis.

Researchers do not know why some people with the same health condition are susceptible to the risk of gastric cancer, while others do not. The exact causes of gastric cancer are also unknown. However, some researchers suggested that Age, diet, and stomach disease, such as can increase the risk of developing gastric cancer.

The most common symptoms of gastric cancer are stomach pain, nausea and vomiting, loss of appetite,... and indigestion. However, common symptoms of unexpected weight loss and stomach ulcers can only be found in gastric cancer while iron-deficiency anemia.

According to the statistics provided by the American Cancer Society, in 2019, approximately, 27,510 cases of stomach cancer will be diagnosed (17,230 in men and 10,280 in women) and 11,140 people will die from gastric cancer (6,800 men and 4,340 women).

Overall, the 5-year survival rate for people with gastric cancer is 31%. Cancer diagnosed at the localized stage have a 5 years survival rate of 67%.


Out of many risk factors associated with the onset of cancer, aging may be one of the major risk factors that cause the disease onset as cancer has been found to have a peak incidence between 50 and 70 years of age.

On finding a potential plant that processes anti-invasive cancer activity researchers examined the relationship between consumption of cruciferous vegetables (CV) in the risk of gastric cancer.


According to the meta-analysis that summarize available evidence from epidemiological studies published reports of CV intake and gastric cancer were identified using MEDLINE (PubMed), EMBASE, and Web of Science databases through to the end of September 2012, including 16 case-control and 6 prospective studies,

* The pooled studies showed a significantly inverse association between CV (relative risk = 0.81; 95% confidence interval, 0.75-0.88) intake and gastric cancer risk, with little heterogeneity (Q = 27.27, P = 0.292, I(2) = 12.0%).

* In a separate analysis, the case-control studies of CV intake yielded significant results compared to the borderline statistical significance of CV intake yielded in the prospective studies.


* Moreover, significant results were consistent for high-quality studies, for North American, European, and Asian studies, for studies on males, and for studies on non-cardia gastric cancer.

Based on the findings, researchers said, "... this meta-analysis provides evidence that high intake of CV was inversely associated with the risk of gastric cancer and non-cardia gastric cancer in humans.


Taken altogether, CV with rich phytochemicals may be considered a functional food for the prevention and treatment of gastric cancer, pending the confirmation of the larger sample size and multicenter human study.


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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Cruciferous vegetable consumption and gastric cancer risk: a meta-analysis of epidemiological studies by Wu QJ1, Yang Y, Wang J, Han LH, Xiang YB. (PubMed)