The #CurableSmoothie of Green Tea, Olive and Blueberry for prevention and Treatment of Glomerulonephritis

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.

Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.

Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post

Nominated for shorty award over last 4 years

Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for prevention and treatment of  glomerulonephritis or Diffuse proliferative nephritis

Yield: 2 servings (about 8 ounces each)

1/2 cup olive
1 cup blueberry
1 cup green tea drink (Make from 4 grams of green tea, a slice of ginger and a cup of hot water lipped for 5 minutes, and let cool to room temperature)

1. Place all ingredients in a blender and puree about 1 minute

2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.

3. Serve immediately

The finding of a natural source for treatment of glomerulonephritis has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in large sample size and mutli centers human trials.

Glomerulonephritis is an inflammation of the kidneys caused by the caused by an immune response.

Recent studies back by well known institutions proposed, Green tea, Olive and Blueberry may be the next generation of natural ingredients for prevention and treatment of glomerulonephritis.

Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Due to its commercial values and health effects, green tea now has been cultivated all over the world in suitable climate. According to Dr.Turner JE, green tea component (-)-epigallocatechin-3-gallate (EGCG) mediated glomerulonephritis through ameliorates renal inflammation, tissue damage, and loss of renal function(1).
The Shanghai Tenth People's Hospital of Tongji University study, suggested, EGCG pretreatment period significantly attenuated mortality and renal dysfunction in the progression of immune-mediated glomerulonephritis (GN) by targeting redox and inflammatory pathways(2).

Furthermore, the phytochmical also reversed the progression of crescentic GN by targeting multiple signaling and inflammatory pathways and countering oxidative stress(3).

Resveratrol, a phytochemical in the class of Stilbenoids, found abundantly in grape and blueberry reduced the production of reactive oxygen species (ROS), reduced cell apoptosis, and upregulated heme oxygenase 1 (HO1) in patients with Idiopathic membranous nephropathy (MN)(4).

The Peking Union Medical College and Chinese Academy study said, "resveratrol attenuated proteinuria, immunoglobuin depositon in kidney, and glomerulonephritis as well as immunoglobulins IgG1 and IgG2a in serum in pristane-induced lupus mice"(5).

Omega 3 fatty acids found abundantly in olive might be beneficial for patients with glomerulonephritis through its effects on lipid metabolism, platelet/vessel wall interactions and proteinuria(6) as well as functional status of erythrocyte membrane and probably proximal tubule function(7).

The effectiveness of  Green tea, Olive and Blueberry may serve as cornerstones of pharmaceutical target for further studies in production of a potential medication for reduced risk, complications and treatment of Glomerulonephritis with little or no adverse effects.

People who are at high risk of Glomerulonephritis due to aging, weaken reno function... should drink at least one serving daily and people with Glomerulonephritis should drink no more than 4 servings daily, depending to digestive toleration.
Life style and diet pattern change are necessary.

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References
(1) Glomerulonephritis therapy: is there a role for green tea? by Turner JE1.(PubMed)
(2) The green tea polyphenol (-)-epigallocatechin-3-gallate ameliorates experimental immune-mediated glomerulonephritis by Peng A1, Ye T, Rakheja D, Tu Y, Wang T, Du Y, Zhou JK, Vaziri ND, Hu Z, Mohan C, Zhou XJ.(PubMed)
(3) Green tea polyphenol (-)-epigallocatechin-3-gallate restores Nrf2 activity and ameliorates crescentic glomerulonephritis by Ye T1, Zhen J2, Du Y3, Zhou JK4, Peng A5, Vaziri ND6, Mohan C3, Xu Y7, Zhou XJ8.(PubMed)
(4) Resveratrol ameliorates renal damage, increases expression of heme oxygenase-1, and has anti-complement, anti-oxidative, and anti-apoptotic effects in a murine model of membranous nephropathy by Wu CC1, Huang YS2, Chen JS3, Huang CF4, Su SL5, Lu KC6, Lin YF7, Chu P3, Lin SH3, Sytwu HK8.(PubMed)
(5) Resveratrol possesses protective effects in a pristane-induced lupus mouse model by Wang ZL1, Luo XF1, Li MT1, Xu D1, Zhou S1, Chen HZ2, Gao N1, Chen Z1, Zhang LL1, Zeng XF1.(PubMed)
(6) [Effect of treating glomerulonephritis with omega 3 fatty acids for selected parameters of hemostasis, blood platelet function and lipid metabolism].[Article in Polish] by Małyszko JS1, Małyszko J, Pawlak K, Myśliwiec M.(PubMed)
(7) [The effect of administering Omega-3 acids on lipids in serum, functional state of erythrocyte membrane and function of the kidneys in patients with primary glomerulonephritis].[Article in Polish] by Fox J1, Manitius J, Debska-Slizień A, Rutkowski B, Nowak J, Bautembach S, Owczarzak A.(PubMed)

The #CurableSmoothie of Avocado, Banana, Yogurt, Plain Chocolate and Vitamin D fortified low fat milk for Treatment of Gitelman syndrome

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.

Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.

Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post

Nominated for shorty award over last 4 years

Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for treatment of Gitelman syndrome

Yield: 2 servings (about 8 ounces each)

1/2 cup avocado
1/2 cup banana
1/4  cup yogurt
1/4 plain chocolate
1 cup vitamin D fortified low fat milk

1. Place all ingredients in a blender and puree about 1 minute

2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.

3. Serve immediately

The finding of a natural source for treatment of Gitelman syndrome has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in large sample size and mutli centers human trials.

Gitelman syndrome is an autosomal recessive distal renal tubular disorder caused by defective sodium chloride transporters inducing hypokalaemic metabolic alkalosis, hypomagnesaemia and hypocalciuria(1). In other words it is a kidney disease caused by an imbalance of ions of potassium, magnesium, and calcium. Recent study lead by the University of Padova suggested that patients with Gitelman syndrome are associated to increase existence of reactive oxygen species (ROS) and oxidative stress of that status could offer chances for new therapeutic targets in disease characterized by high levels of reactive oxygen species(2).
According to the Royal Liverpool and Broadgreen University Hospitals NHS Trust. treatment of Gitelman syndrome may include oral potassium supplement, weekly intravenous potassium and magnesium infusion, correction of vitamin D level and the offering of appropriate dietary advice(3).

Avocado and banana rich in potassium and yogurt and  plain chocolate may be used a daily dietary sources for treatment of Gitelman syndrome in replacement of oral potassium and magnesium supplements.

In take of vitamin D fortified low fat milk should also be necessary for increased absorption of calcium according to study. Furthermore dietary change plays an important role to maintain right levels of potassium, magnesium, and calcium in the blood for prevention of the syndrome induced complications.

The combination of  Avocado, Banana, Yogurt, Plain Chocolate and Vitamin D fortified low fat milk  smoothie may hold a key in further studies in production of an effective natural ingredients for  treatment of Gitelman syndrome without inducing adverse effects.
People with Gitelman syndrome should drink as much as they can depending to the digestive toleration.

Dietary change with lot of vegetables, fruits and deep sea fish will be helpful in reduced risk of muti nutrients deficiency case of syndrome exaggeration.


All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

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References
(1) Management of a severe case of Gitelman syndrome with poor response to standard treatment b Koudsi L1, Nikolova S1, Mishra V1.(PubMed)
(2) Bartter/Gitelman syndromes as a model to study systemic oxidative stress in humans by Maiolino G1, Azzolini M1, Rossi GP1, Davis PA2, Calò LA3(PubMed)
(3) Management of a severe case of Gitelman syndrome with poor response to standard treatment by Koudsi L1, Nikolova S1, Mishra V1.(PubMed)

The #CurableGmoothie of Green Tea and Grape for reduced risk and Treatment of Impetigo

Kyle J. Norton(Scholar, master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


The smoothie for Reduced risk and Treatment of Impetigo
Yield: 2 serving (about 8 ounce each)
1 cup Blueberry
1/4 cup avocado
1/4 cup raw flax seed
1 cup of rice milk


1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately


The dream of finding the natural ingredient for prevention and treatment of infectious skin diseases, such as  Impetigo, without adverse effects in replacement of conventional medication has not been abated. Some ingredients have to discard because of not achieving the same potent results in human trials.
Scientist community may have found the smoothie(combined ingredients of garlic, olive and coconut oils) with potential and therapeutic value for reduced risk and treatment of Impetigo without adverse effects.

Impetigo is a contagious skin disease infection affecting mostly children and infants.

According to the recent studies by the well known institutions, green tea(3) and Grapes(1) , may hold a key for potential and therapeutic values for attenuated symptoms and treatment of Impetigo.

Green tea contains more amount of antioxidants than any drinks or food with the same volume, and is the leaves of Camellia sinensis, undergone minimal oxidation during processing, originated from China. According to the, it extract has exhibited weak antibacterial effect of amoxicillin in methicillin-resistant Staphylococcus aureus infected mice(3). But its polyphenols (TPP), showed a significant effects in the same methicillin-resistant Staphylococcus aureus (MRSA, the bacteria also responsible for induction of Impetigo in children and infants) through regulating the expression of various proteins in Staphylococcus aureus (MRSA)(4).

Against streptococcus pyogenes, one of bacteria induced contagious skin infection, Epigallocatechin Gallate (EGCG) isolated from green tea, displayed antimicrobial properties at various concentrations, through effectively reduced GAS bacteria cellular attachment and induced GAS cell death(5).

Resveratrol is a phytochemical in the class of Stilbenoids, found abundantly in grape inhibited also methicillin-resistant Staphylococcus aureus through disturbing the expression of genes related to QS in bacterial density(6), through its antioxidant activity(1). According to the joint study by the Capital Medical University, resveratrol of the polyphenols, inhibited the methicillin-resistant Staphylococcus aureus (MRSA), determined by the checkerboard agar dilution method(7).

Dr. Sakagami Y and colleagues at the Kinki University said" Two resveratrol trimers, gnemonol B isolated from Gnetum gnemon and gnetin E,....exhibit strong antibacterial activities against vancomycin-resistant Enterococci (VRE) and methicillin-resistant Staphylococcus aureus (MRSA)" and ",(may be used) alone or in combination with antibiotics might be useful in controlling and treating VRE and MRSA infections"(2).

Taking altogether, intake of combination of green tea and grape may as a cornerstone for further investigation of the validation.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

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References

(1) New stilbene derivatives from Calligonum leucocladum by Okasaka M1, Takaishi Y, Kogure K, Fukuzawa K, Shibata H, Higuti T, Honda G, Ito M, Kodzhimatov OK, Ashurmetov O.(PubMed)

(2) Antibacterial activity of stilbene oligomers against vancomycin-resistant Enterococci (VRE) and methicillin-resistant Staphylococcus aureus (MRSA) and their synergism with antibiotics by Sakagami Y1, Sawabe A, Komemushi S, All Z, Tanaka T, Iliya I, Iinuma M.(PubMed)

(3) Green tea extract weakens the antibacterial effect of amoxicillin in methicillin-resistant Staphylococcus aureus infected mice by Peng Q1, Huang Y, Hou B, Hua D, Yao F, Qian Y.(PubMed)

(4) Antibacterial effects of green tea polyphenols on clinical isolates of methicillin-resistant Staphylococcus aureus by Cho YS1, Schiller NL, Oh KH.(PubMed)

(5) Evaluation of the antimicrobial efficacy of green tea extract (egcg) against streptococcus pyogenes in vitro - biomed 2011 by Hull Vance S1, Tucci M, Benghuzzi H.(PubMed)

(6) RNA-Seq-based transcriptome analysis of methicillin-resistant Staphylococcus aureus biofilm inhibition by ursolic acid and resveratrol by Qin N1, Tan X2, Jiao Y3, Liu L4, Zhao W5, Yang S6, Jia A7.(PubMed)

(7) Studies of the in vitro antibacterial activities of several polyphenols against clinical isolates of methicillin-resistant Staphylococcus aureus by Su Y1, Ma L2, Wen Y3, Wang H4, Zhang S5.(PubMed)

All About #CurableVitamins: The effect of Vitamin D on Asthma

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Vitamins are organic compounds and vital nutrients needed by your body to grow and develop in a profound way.

Vitamin D
Vitamin D is a fat-soluble secosteroids found in small amount in few foods, including salmon, mackerel, sardines and tuna. The vitamin plays an important role in modulation of cellular proliferation, apoptosis induction, tumor growth suppression and promotion in absorption of minerals, including calcium, iron, magnesium, phosphate and zinc.

    The Effect of Vitamin D on Asthma

The widespread of incidence of asthma over large 20 years in South East Asian population, specially in children and aging group has caused some concerns to the government and scientific community. It may be due to over intake in artificial ingredients, polluted environment as well as intake foods triggering the inflammatory allergens.


1. Serum of vitamin D
Epidemiological studies, linking the levels of serum 25-OH vitamin D with asthma may be inconclusive. The study of included 4,999 adults aged 30-60 years in 1999-2001. 3,032 of those included at baseline also participated at a follow-up examination 5 years later and 3,727 answered a 10 year follow-up questionnaire, showed no association of serum serum 25-OH vitamin D and the risk of asthma in Danish adults(1)(1a). Some researchers in the study of general Korean population suggested that vitamin D-insufficiency may have an increased likelihood of atopic dermatitis, but not asthma, allergic rhinitis, or IgE sensitization(2)(2a). But the study by Royal Brompton Hospital, London indicated otherwise of relationships between serum vitamin D, lung function, and pathology in children with severe, therapy-resistant asthma (STRA)(3)(4) and 25 hydroxy vitamin D insufficiency wass associated with bronchial asthma(4a) On the other hand, the study of iMayo Clinic indicated the correlation between serum 25(OH)D concentrations and positive pneumococcal antibody levels in all subjects regardless of asthma(5).

2. The benefits
According to the study by Universitätsmedizin Berlin, oral administration of vitamin D in vitamin D deficiency induced asthma, showed an increased expression of CD38 on B cells and a decreased T-cell-dependent proinflammatory cytokine production(6). In support to above study, Vitamin D found to decreased inflammatory cytokine production from T-cell subsets implicated in asthma, according to Florida Atlantic University(7). In patient with steroid-resistant (SR) and steroid-sensitive (SS) asthma, oral administration of vitamin D, although exerted its anti-inflammatory and corticosteroid-enhancing effects in monocytes of patients with SR asthma and patients with SS asthma, the responses to corticosteroids in patients with SR asthma remained significantly lower than those in patients with SS asthma(8). Other in the study of the effect of vitamin D in severe therapy-resistant asthma (STRA) patients, showed an positive effect of 1α,25-dihydroxyvitamin D3, the active form of vitamin D in culture enhanced dexamethasone-induced IL-10 (Defective IL-10 expression causes a significantly diminished levels of anti-inflammatory interleukin (IL)-10))without marked effects on IL-13 or IL-17A production(9). Patients with severe asthma exhibited increased levels of TH17 cytokines.The study of King's College London, also suggested that 1,25(OH)2D3 inhibits TH17 cytokine production in all patients with moderate-to-severe asthma(10), enhances the frequency of Treg cells(11)and upregulates CD200 on peripheral human CD4+ T cells(12).

Taken altogether, without going into reviews, vitamin D used conjunction with other anti asthma medicine and its the active form 1α,25-dihydroxyvitamin D3, may be associated to reduced risk and treatment of asthmatic diseases. Over doses of vitamin D supplement may cause excessive calcium absorption, calcification, Urinary stones etc. please make sure to follow the guideline of the Institute of Medicine of the National Academies.


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References
(1) The association of serum 25-OH vitamin D with atopy, asthma, and lung function in a prospective study of Danish adults by Thuesen BH1, Skaaby T, Husemoen LL, Fenger M, Jørgensen T, Linneberg A.(PubMed)
(1a) Vitamin d in pediatric inpatients with respiratory illnesses by Iqbal S1, Mosenkis EV, Jain P, Wiles A, Lerner J, Benton AS, Chamberlain JM, Freishtat RJ, Teach SJ.(PubMed)
(2) Low vitamin D levels are associated with atopic dermatitis, but not allergic rhinitis, asthma, or IgE sensitization, in the adult Korean population by Cheng HM1, Kim S2, Park GH3, Chang SE4, Bang S5, Won CH4, Lee MW4, Choi JH4, Moon KC(PubMed)
(2a) Vitamin D with asthma and COPD: not a false hope? A systematic review and meta-analysis By Zhang LL1, Gong J2, Liu CT3.(PubMed)
(3) Childhood asthma and vitamin D deficiency in Turkey: is there cause and effect relationship between them? Uysalol M1, Mutlu LC, Saracoglu GV, Karasu E, Guzel S, Kayaoglu S, Uzel N.(PubMed)
(4) Relationship between serum vitamin D, disease severity, and airway remodeling in children with asthma by Gupta A1, Sjoukes A, Richards D, Banya W, Hawrylowicz C, Bush A, Saglani S.(PubMed)
(4a) Serum 25 Hydroxy Vitamin D Insufficiency Associated with Bronchial Asthmain Lucknow, India by Awasthi S1, Vikram K.(PubMed)
(5) Serum 25-hydroxyvitamin D is associated with enhanced pneumococcal antibody levels in individuals with asthma by Lee J1, Zhao H, Fenta Y, Kita H, Kumar R, Juhn YJ.(PubMed)
(6) Oral vitamin D increases the frequencies of CD38+ human B cells and ameliorates IL-17-producing T cells by Drozdenko G1, Heine G, Worm M.(PubMed)
(7) Effect of vitamin D on T-helper type 9 polarized human memory cells in chronic persistent asthma by Keating P1, Munim A2, Hartmann JX2.(PubMed)
(8) Anti-inflammatory and corticosteroid-enhancing actions of vitamin D in monocytes of patients with steroid-resistant and those with steroid-sensitiveasthma by Zhang Y1, Leung DY2, Goleva E3.(PubMed)
(9) Defective IL-10 expression and in vitro steroid-induced IL-17A in paediatric severe therapy-resistant asthma by Gupta A1, Dimeloe S, Richards DF, Chambers ES, Black C, Urry Z, Ryanna K, Xystrakis E, Bush A, Saglani S, Hawrylowicz CM.(PubMed)
(10) Enhanced production of IL-17A in patients with severe asthma is inhibited by 1α,25-dihydroxyvitamin D3 in a glucocorticoid-independent fashion by Nanzer AM1, Chambers ES, Ryanna K, Richards DF, Black C, Timms PM, Martineau AR, Griffiths CJ, Corrigan CJ, Hawrylowicz CM.(PubMed)
(11) The role of 1α,25-dihydroxyvitamin D3 and cytokines in the promotion of distinct Foxp3+ and IL-10+ CD4+ T cells by Urry Z1, Chambers ES, Xystrakis E, Dimeloe S, Richards DF, Gabryšová L, Christensen J, Gupta A, Saglani S, Bush A, O'Garra A, Brown Z, Hawrylowicz CM.(PubMed)
(12) 1α,25-dihydroxyvitamin D3 promotes CD200 expression by human peripheral and airway-resident T cells by Dimeloe S1, Richards DF, Urry ZL, Gupta A, Stratigou V, Farooque S, Saglani S, Bush A, Hawrylowicz CM.(PubMed)

The #Curablesmoothie of Green Tea, Strawberry and Grape for Prevention and Treatment of Syphilis

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for prevention and treatment of Syphilis
Yield: 2 servings (about 8 ounces each)
1 cup grape
1/2 cup mango or strawberry
1 cup green tea drink (Make from 4 grams of green tea, a slice of ginger and a cup of hot water lipped for 5 minutes, and let cool to room temperature)
1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately

The dream of finding the natural ingredient for prevention and treatment of Syphilis without adverse effects in replacement of conventional medication has not been abated. Some ingredients have to discard because of not achieving the same potent results in human trials.

Scientist community may have found the smoothie(combined ingredients of garlic, olive and coconut oils) with potential and therapeutic value for reduced risk and treatment of  Syphilis without adverse effects.

Syphilis is an chronic sexual transmission infectious disease caused by baterium Treponema pallidum subspecies pallidum. In some cases, the infection also affect the developing fetus, according to the CDC Fact Sheet.

Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Due to its commercial values and health effects, green tea now has been cultivated all over the world in suitable climate. According to the Creighton University, epigallocatechin gallate, theaflavins isolated from green tea may have a potential to prevent sexually transmitted infections caused by infectious virus)(1).
The Int J Antimicrob Agents. 2006 Feb;27(2):181. insisted that green tea major chemical constituent (-)-epigallocatechin gallate inhibit cytoplasmic membrane function, and that licochalcones A and C inhibit energy metabolism of that exhibited anti microbial induced infectious disease(3)

Flavonoids, found abundantly in apple and from the leaves of Oncoba spinosa Forssk. (Salicaceae) used to treat human diseases, anti-infective research due to its antifungal, antiviral and antibacterial activity, epidemiological studies suggested(3), exhibited strong radical-scavenging activities against bacteria through anti microbial and enhanced immune effects(2) for treatment of syphilis, wounds and sexual impotence(2).

 Phenolic acids, found abundantly in tea, mango, strawberries, rhubarb, soy, etc. according to epidemiological studies expressed strongly anti viral and microbial and antifungal activities and cytotoxicity(4), including bacteria induced Syphilis. According to the University of KwaZulu-Natal Pietermaritzburg, Phenolic Acids extraced from certain herbal medicine exhibited anti Bacillus subtilis and Staphylococcus aureus, Escherichia coli and Klebsiella pneumoniae, a filamentus yeast-like fungus (Candida albicans) and a free-living nematode (Caenorhabditis elegans), through their good antibacterial, antifungal and anthelmintic activity (5).
The Instituto de Fermentaciones Industriales/CIAL (CSIC) study of Phenolic acids, also showed a significant inhibited effects against the growth of lactobacilli (Lactobacillus paraplantarum LCH7, Lactobacillus plantarum LCH17, Lactobacillus fermentum LPH1, L. fermentum CECT 5716, Lactobacillus brevis LCH23, and Lactobacillus coryniformis CECT 5711) and pathogens (S. aureus EP167 and C. albicans MY1055)(6).

Resveratrol a phytochemical in the class of Stilbenoids, found abundantly in skins and seed of grape wine, nuts, peanuts, etc. also exhibited anti microbial and viral effect includiing Helicobacter pylori, according to joint study conducted by University of Anhui Science and Technology, Bengbu 233100, China(7).

In the study of Microbial metabolism, Dr. Herath W and colleagues at the The University of Mississippi, said, "resveratrol tends to lose its anti-inflammatory, cytotoxic and anti-oxidant activities with the substitution of its hydroxyl groups"(8) even the phytochemical has shown significant anti viral and microbial activities against infection and inflammation(9).

The Smoothie of Green Tea, Strawberry and Grape  may hold a key for further studies in production of a curable natural remedy for prevention and treatment of Syphilis.

People who are at  increased risk of  Syphilis due to family history, weaken immunity, sexual orientation, ....should drink at least one cup or more daily. People with  Syphilis may drink as much as they can, depending to the digestive toleration.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/p/general-health.html

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

References

(1) Natural polyphenols: potential in the prevention of sexually transmitted viral infections by Date AA1, Destache CJ2(PubMed)
(2) Antimicrobial and antioxidant flavonoids from the leaves of Oncoba spinosa Forssk. (Salicaceae) by Djouossi MG1, Tamokou JD2, Ngnokam D3, Kuiate JR4, Tapondjou LA5, Harakat D6, Voutquenne-Nazabadioko L7.(PubMed)
(3) Antimicrobial activity of flavonoids by Cushnie TP, Lamb AJ.(PubMed)
(4) Cytotoxicity, antiviral and antimicrobial activities of alkaloids, flavonoids, and phenolic acids by Ozçelik B1, Kartal M, Orhan I.(PubMed)
(5) Antimicrobial, Anthelmintic Activities and Characterisation of Functional Phenolic Acids of Achyranthes aspera Linn.: A Medicinal Plant Used for the Treatment of Wounds and Ringworm in East Africa by Ndhlala AR1, Ghebrehiwot HM2, Ncube B3, Aremu AO3, Gruz J4, Šubrtová M4, Doležal K4, du Plooy CP5, Abdelgadir HA1, Van Staden J3.(PubMed)
(6) Antimicrobial activity of phenolic acids against commensal, probiotic and pathogenic bacteria by Cueva C1, Moreno-Arribas MV, Martín-Alvarez PJ, Bills G, Vicente MF, Basilio A, Rivas CL, Requena T, Rodríguez JM, Bartolomé B.(PubMed)
(7) Resveratrol Protects against Helicobacter pylori-Associated Gastritis by Combating Oxidative Stress by Zhang X1, Jiang A2, Qi B3, Ma Z4, Xiong Y5, Dou J6, Wang J7,8.(PubMed)
(8) Microbial metabolism. Part 14. Isolation and bioactivity evaluation of microbial metabolites of resveratrol by Herath W1, Khan SI, Khan IA.(PubMed)
(9) Resveratrol is cidal to both classes of Haemophilus ducreyi by Nawrocki EM1, Bedell HW, Humphreys TL.(PubMed)

All About #CurableVitamins: The effect of Vitamin D on Skin Aging

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Vitamins are organic compounds and vital nutrients needed by your body to grow and develop in a profound way.

Vitamin D
Vitamin D is a fat-soluble secosteroids found in small amount in few foods, including salmon, mackerel, sardines and tuna. The vitamin plays an important role in modulation of cellular proliferation, apoptosis induction, tumor growth suppression and promotion in absorption of minerals, including calcium, iron, magnesium, phosphate and zinc.

    The Effect of Vitamin D on Skin Aging

Skin aging is one of most visible process which occurs constantly in our skin organ. According to the Clinical Centre of Nis, certain plant extracts may have the ability to scavenge free radicals, to protect the skin matrix through the inhibition of enzymatic degradation, or to promote collagen synthesis in the skin, affect skin elasticity and tightness(a). Other suggested that free radicals induced domino effects in production of reactive oxygen species, can react with DNA, proteins, and fatty acids, causing oxidative damage and impairment of antioxidant system, leading injuries damage regulation pathways of skin, including wrinkles, roughness, appearance of fine lines, lack of elasticity, and de- or hyperpigmentation marks(b).


1. Plasma of vitamin D
Levels of 25-hydroxyvitamin D levels [25(OH)D] was associated to risk of skin aging as the study at Universitätsklinikum des Saarlandes showed. UV-radiation exerts both skin aging -promoting and -inhibiting effects on skin aging. Altered mineral homeostasis caused by a high vitamin D activity, exhibited the premature agingthat include, such as short lifespan, retarded growth, ectopic calcification, immunological deficiency, osteoporosis, atherosclerosis, hypogonadism, skin and general organ atrophy but in laboratory investigations, vitamin D compounds protects the skin against the hazardous effects of various skin aging-inducing agents, including ultraviolet (UV) radiation(1). Therefore optimal serum concentration are necessary due to its U-shaped risk(2). The Stanford University School of Medicine study indicated that vitamin D deficiency enhanced low scores for specific photodamage parameters including erythema/telangiectasias, hyperpigmentation, and wrinkling(3), specially, the skin from aging subjects can decrease by greater than twofold the capacity of the skin to produce previtamin D3(4).

2. The effects
According to Treviglio-Caravaggio Hospital, daily supplementation of vitamin D indicated is about 800-1,000 IU/day but may increase up to a maximum dose of 2,000 IU/day in conditions of severe vitamin D deficiency with a concomitant reduced or no sun exposure, reduced dietary intake and reduced calcium absorption(5)(6). Some researchers suggested that intrinsic skin aging may reflects the reduction processes that are common in internal organs, as the reduced production of sex hormones influence skin morphology and functions, skinpermeability, wound healing, sebaceous lipogenesis, and the metabolism of skincells in both sex and Vitamin D administered and antioxidant treatment may be beneficial(7). In postmenopausal health, low levels of vitamin D may induce obesity, malabsorption syndromes, medication use (e.g. anticonvulsants, antiretrovirals),skin aging. According to Universidad de Zaragoza, Increased level of the vitamin D through regular sunlight exposure (without sunscreens) for 15 min, 3-4 times a week, in the middle of the day in summer may be beneficial, but supplementation intake of vitamin D2 (ergocalciferol) or vitamin D3 (cholecalciferol) should be monitored depending on the dose used and the presence of concomitant medical conditions such as renal disease(8). Dr Johnson MA at the University of Georgia, insisted " Diminished synthesis of vitamin D in theskin that occurs with aging and poor dietary intake contribute to the high prevalence of poor vitamin D status in older adults"(9). Cutaneous vitamin D3 synthesis declines with age, it would require input of an additional 2600 iu/d (65 microg/d) of oral vitamin D3 to ensure that 97.5% of older women have 25(OH)D values at or above desirable levels (10).

Taken altogether, optimal serum concentration was found to interact in enhancing production of sex hormones and reducing photodamage parameters including erythema/telangiectasias, hyperpigmentation, and wrinkling due to aging. As always, all articles written by Kyle J. Norton are for information & education only, please consult your Doctor & Related field specialist before applying



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References
(1) Unravelling of hidden secrets: The role of vitamin D in skin aging by Reichrath J.(PubMed)
(2) Vitamin D and aging by Tuohimaa P.(PubMed)
(3) Association of facial skin aging and vitamin D levels in middle-aged white women by Chang AL1, Fu T, Amir O, Tang JY.(PubMed)
(4) Aging decreases the capacity of human skin to produce vitamin D3 by MacLaughlin J, Holick MF.(PubMed)
(5) Vitamin D: role and opportunity to prescribe by Resmini G1, Tarantino U, Iolascon G.(PubMed)
(6) Vitamin D and aging by Gallagher JC.(PubMed)
(7) Hormonal therapy of intrinsic aging by Zouboulis CC1, Makrantonaki E.(PubMed)
(8) EMAS position statement: Vitamin D and postmenopausal health by Pérez-López FR1, Brincat M, Erel CT, Tremollieres F, Gambacciani M, Lambrinoudaki I, Moen MH, Schenck-Gustafsson K, Vujovic S, Rozenberg S, Rees M(PubMed)
(9) Nutrition and aging--practical advice for healthy eating by Johnson MA(PubMed)
(10) Barriers to optimizing vitamin D3 intake for the elderly by Heaney RP.(PubMed)

The #CurableSmoothie of Green Tea, Coffee and Tomato for Prevention and Treatment of Liver Cancer

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for prevention and treatment of  Liver cancer
Yield: 2 serving (about 8 ounce each)
3/4 cup tomato
1/2 cup coffee
1 cup green tea drink (Make from 4 grams of green tea and a cup of hot water lipped for 5 minutes, and let cool to room temperature)

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

The finding of a natural source for treatment of  Liver cancer has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in large sample size and mutli centers human trials.

Recent studies back by renowned institutions, conveyed that Green Tea(3), Coffee(4) and Tomato(7) may be holding a key for extracting natural ingredient for reduced early onset and treatment of Liver cancer.
Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Due to its commercial values and health effects, green tea now has been cultivated all over the world in suitable climate. According to the Tohoku University Graduate School of Medicine, Regular comsumption of green tea is associated with a reduced risk of liver cancer incidence(1).

Liver cancer is defined as a condition of out of controlled growth of hepatocellular cells in the liver. Since the organ is a soft tissue with less nerve, most liver cancer patient are diagnosed in the later stage of the cancer. According to the statistic, liver cancer remains the fifth most common malignancy in men and the eighth in women worldwide. Hepatocellular carcinoma (HCC) is a common form of primary liver cancer.

The Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University study in the review of nine prospective cohort articles involving 465,274 participants and 3694 cases of liver cancer from China, Japan, and Singapore, suggested that green tea exhibited a preventive effects on the risk for liver cancer in female Asian populations. However, additional studies are needed to make a convincing case for this association(2).

Epidemiologically, according to Dr. Fon Sing M and colleagues, consumption of green tea have an adverse relation with the onset of primary liver cancer(3).

Coffee is a brewed drink prepared from roasted coffee beans from the Coffee plant. According to the Japan Public Health Center-Based Prospective Study Group, regardless to hepatitis C (HCV) and B virus (HBV) infection, regular consumption may reduce the risk of liver cancer(4).In a prospective study in Japan, consisting 90,452 middle-aged and elderly Japanese subjects (43,109 men and 47,343 women) found that habitual coffee drinking may be associated with reduced risk of hepatocellular carcinoma (HCC)(5).

Dr. Petrick JL and the researchers at the The Liver Cancer Pooling Project convinced, coffee consumption is associated with reduced risk of HCC, particular in women(6).

Tomato is a red, edible fruit, genus Solanum, belongs to family Solanaceae, native to South America. Because of its health benefits, tomato is grown world wide for commercial purpose
and often in green house. Its phytochemical lycopene is found to associated to liver prevention used conjunction with the formula Sho-saiko-to, the Kagawa Medical University confirmed(7).In Obese animal model, dietary lycopene can prevent (High fat diet) HFD-promoted hepatocellular carcinoma (HCC) incidence and multiplicity in mice, depending on antibody gene BCO2 expression in elicited different mechanisms(8).

Furthermore, Apo-10'-lycopenoic acid (apo-10-lycac), a metabolite of lycopene, ameliorated the HFD-promoted hepatic tumorigenesis by in stimulating the cell survival mechanism of SIRT1 gene(9).

The finding of the effectiveness of Green Tea, Coffee and Tomato may serve as cornerstones of pharmaceutical target for further studies as well as a potential medication for treatment of  Liver cancer 

People who are at increased risk of Liver cancer , due to family history, auto immunity,....should drink the juices at least one a day. People with Liver cancer  should drink the juice as much as  as they can depending to digestive toleration.

Life style and diet pattern change are recommended.

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By addressing the Underlying Causes through Clinical Trials and Studies

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Holistic System In Existence That Will Show You How To

Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

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References
(1) Green tea consumption and the risk of liver cancer in Japan: the Ohsaki Cohort study by Ui A1, Kuriyama S, Kakizaki M, Sone T, Nakaya N, Ohmori-Matsuda K, Hozawa A, Nishino Y, Tsuji I.(PubMed)
(2) Green tea and liver cancer risk: A meta-analysis of prospective cohort studies in Asian populations. by Huang YQ1, Lu X2, Min H1, Wu QQ1, Shi XT1, Bian KQ1, Zou XP3.(PubMed)
(3) Epidemiological studies of the association between tea drinking and primary liver cancer: a meta-analysis by Fon Sing M1, Yang WS, Gao S, Gao J, Xiang YB.(PubMed)
(4) Effect of coffee and green tea consumption on the risk of liver cancer: cohort analysis by hepatitis virus infection status by Inoue M, Kurahashi N, Iwasaki M, Shimazu T, Tanaka Y, Mizokami M, Tsugane S; Japan Public Health Center-Based Prospective Study Group(PubMed)
(5) Influence of coffee drinking on subsequent risk of hepatocellular carcinoma: a prospective study in Japan by Inoue M1, Yoshimi I, Sobue T, Tsugane S; JPHC Study Group(PubMed)
(6) Coffee Consumption and Risk of Hepatocellular Carcinoma and Intrahepatic Cholangiocarcinoma by Sex: TheLiver Cancer Pooling Project. by Petrick JL1, Freedman ND2, Graubard BI2, Sahasrabuddhe VV2, Lai GY3, Alavanja MC2, Beane-Freeman LE2, Boggs DA4, Buring JE5, Chan AT6, Chong DQ7,Fuchs CS8, Gapstur SM9, Gaziano JM10, Giovannucci EL11, Hollenbeck AR12, King LY6, Koshiol J2, Lee IM5, Linet MS2, Palmer JR4, Poynter JN13, Purdue MP14, Robien K15, Schairer C2, Sesso HD5, Sigurdson AJ2, Zeleniuch-Jacquotte A16, Wactawski-Wende J17, Campbell PT9, McGlynn KA2.(PubMed)
(7) Effects of lycopene and Sho-saiko-to on hepatocarcinogenesis in a rat model of spontaneous liver cancer by Watanabe S1, Kitade Y, Masaki T, Nishioka M, Satoh K, Nishino H.(PubMed)
(8) Lycopene attenuated hepatic tumorigenesis via differential mechanisms depending on carotenoid cleavage enzyme in mice by Ip BC1, Liu C2, Ausman LM1, von Lintig J3, Wang XD4.(PubMed)
(9) Lycopene metabolite, apo-10'-lycopenoic acid, inhibits diethylnitrosamine-initiated, high fat diet-promoted hepatic inflammation and tumorigenesis in mice by Ip BC1, Hu KQ, Liu C, Smith DE, Obin MS, Ausman LM, Wang XD.(PubMed)