Endometriosis also reacts to hormone signals of the monthly menstrual cycle, by building and breaking up tissues and eliminating them through the menstrual period.
According to the statistics provided by the Clinical Center of Niš,
* About 20% of reproductive age women with endometriosis are assymptomatic
* About 55% of women have developed the new onset of severe menstrual cramps
* About 25% of women with sub-fertility (less fertile than a normal couple), depending on the stages of endometriosis.
Endometriosis can be classified into 4 stages
* Minimal stage
The top surface, few in number. Commonly they are found in the inside wall of uterus, ligaments, and ovary, causing a significant reduction in both progesterone and its ratio with 17 beta-oestradiol, luteal dysfunction and abnormal secretory patterns(3). Minimal stage endometriosis may lead to unexplained causes of infertility(2).
* Mild stage
Deeper implants, greater numbers are presented. Commonly found in the same area as a minimal stage, causing worsening of oocyte quality. Mild stage of endometriosis may lead to infertility(4).
* Moderate stage:
Many implants, endometrial cysts are presented, affecting ovary function, and causing scar tissues and adhesion.
* Severe stage:
Intensive peritoneal implants, large endometriomas are presented with dense adhesion.
Conventionally, most cases of endometriosis are treated by pain medicines such as NSAIDs (non-steroidal anti-inflammatory drugs) and hormone therapy such as birth control pills with an aim to reduce pain and improve quality of life, including daily activity.
Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.
The root has been used in traditional and Chinese medicine for the treatment of dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
Researchers in the urgency to find natural compounds for the treatment of endometriosis with no side effects evaluated the efficacy and safety of acupuncture-moxibustion combined with modified Mojie tablet containing ginger in the prevention of the recurrence of endometriosis (EMS) after laparoscopic surgery.
The study included 120 cases of EMS after laparoscopic surgery, randomly assigned into an acupuncture-moxibustion group, a western medication group, a Chinese medication group and a combined therapy of acupuncture-moxibustion and Chinese medication group (combined therapy group).
Each group containing 30 participants was separated, before treatment, after treatment, in 3 months after treatment and in 6 months after treatment.
In the acupuncture-moxibustion group, acupuncture was applied at Xuehai (SP 10), Sanyinjiao (SP 6) and Guanyuan (CV 4); the isolated moxibustion with ginger was used at Guanyuan (CV 4), once a day, twice a week.
In the western medication group, gestrinone was prescribed for oral administration, 2.5 mg, once a day, twice a week.
In the Chinese medication group, the self-prepared Mojie tablet was prescribed for oral administration.
And, in the combined therapy group, acupuncture, moxibustion and modified Mojie tablet for oral administration were used in combination.
In 3 and 6 months after treatment, the positive rates of EHP-5 score were 0% (0/30) in the combined therapy group and 0% (0/30) in the acupuncture-moxibustion group, compared to the lower significantly than 13.3% (4/30) in the western medication group.
In follow-up stage of 6 months after treatment, according to the abdominal ultrasound examination, there was no recurrence case in the combined therapy group, compared to the lower than 13.3% (4/30) in the western medication group.
According to assays, the serum CA125 detection in the combined therapy group did not find any abnormal case, compared to the lower than 16.7% (5/30) in the western medication group (P < 0.05).
Based on the results, researchers wrote in the final report, "Acupuncture and moxibustion combined with modified Mojie tablet effectively prevent the recurrence of EMS after laparoscopic surgery and improve the life quality of the patients".
Take all together, ginger may be used combined with other traditional medicine and therapies for the prevention and treatment of endometriosis and recurrent endometriosis, pending to the confirmation of large sample size and multicenter human study.
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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.
Sources
(1) [Efficacy observation on the combination of acupuncture and Chinese medication in prevention of the recurrence of endometriosis after laparoscopic surgery] [Article in Chinese] by Zhang XY, Zhang CY. (PubMed)
(2) Mid to late luteal phase steroids in minimal stage endometriosis and unexplained infertility.
Barry-Kinsella C1, Sharma SC, Cottell E, Harrison RF(PubMed)
(3) Cyclical gonadotrophin and progesterone secretion in women with minimal endometriosis by Williams CA, Oak MK, Elstein M.(PubMed)
(4) Follicular fluid from infertile women with mild endometriosis may compromise the meiotic spindles of bovine metaphase II oocytes by Da Broi MG1, Malvezzi H, Paz CC, Ferriani RA, Navarro PA(PubMed)
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