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In the study of " Vitamin K, circulating cytokines, and bone mineral density in older men and women" by Shea MK, Dallal GE, Dawson-Hughes B, Ordovas JM, O'Donnell CJ, Gundberg CM, Peterson JW, Booth SL., posted in US National Library of Medicine National Institutes of Health, found that Poor vitamin K status was associated with high concentrations of cytokines involved in bone turnover, but vitamin K supplementation did not confer a decrease in cytokine concentrations. The healthy status of this cohort may explain a lack of effect of vitamin K supplementation on cytokine concentrations.
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(1) Vitamin K intake and bone mineral density in women and men by Booth SL1, Broe KE, Gagnon DR, Tucker KL, Hannan MT, McLean RR, Dawson-Hughes B, Wilson PW, Cupples LA, Kiel DP.(PubMed)