How to Protect Your Inner Eye Pressure Against Early Onset of Glaucoma

Intake of fennel may have a potential and positive effect in reduced ocular hypertension, the early onset of glaucoma, some scientists suggested.

The results of this investigation were conducted by numbers of respectable research centers, including Delhi Institute of Pharmaceutical Sciences & Research and published on online medical literature.

Ocular hypertension is a condition characterized by elevated fluid pressure inside the eye (intraocular pressure), in most case, without inducing optic nerve damage or visual field loss.

Normal eye pressure is in ranges between 10-21 mm Hg. Eye pressure over 21mm Hg is considered as ocular hypertension.

People with ocular hypertension do not develop a peripheral vision and ocular disease. However, the condition may consider as a risk factor in the early onset of glaucoma.

Medication such as bisphosphonate, cyclosporine, tacrolimus,.... and minocycline used for treatment for osteoporosis, erectile dysfunction, and prostate conditions may increase pressure in the ocular.


The Glaucoma Research Foundation, patients with ocular hypertension may not experience any symptoms that affect the inner eye structure or vision abnormality, however untreated ocular hypertension may facilitate glaucoma, a multi-factorial, complex eye disease with specific characteristics such as optic nerve damage and visual field loss.

According to statistic, approximately, 3-6 million people in the United States have intraocular pressures of 21 mm Hg or higher, affecting 4%-10% of the population older than 40 years with no signs of glaucomatous damage.

Fennel (Foeniculum vulgare) is a plant species of the genus, belongings to Apiaceae (Umbelliferae), native to the Mediterranean.

The herb or foot has been used in traditional and herbal medicine as warming, carminative, antispasmodic, antidepressant agent and to stimulate the appetite, ease indigestion, soothe coughing, reduce intestinal spasms, to regulate the menstrual cycle and relieve PMS,...

In the evaluation of the effect of aqueous extract isolated from Foeniculum vulgare in experimental models of glaucoma, researchers at the Delhi Institute of Pharmaceutical Sciences & Research found that application of aqueous seed extract of Foeniculum vulgare exerted significant activities in reduced the intraocular pressure of tested model by 17.49, 21.16 and 22.03%.

In normotensive rabbits, application of the same doses induced an insignificant change of fluid pressure.

These result suggested that aqueous extract isolated from Foeniculum vulgare demonstrated an oculohypotensive activity only on infectious subjects without causing harm to normal eye pressure.
Aqueous extract of Foeniculum vulgare possesses significant oculohypotensive activity similar to those of timolol, a conventional medicine used as an eye drop to treat increased pressure inside the eye such as in ocular hypertension and glaucoma.

Further analysis, researchers also suggested that at a dose of 0.6%, the extract may have potential to treat acute and chronic models of glaucoma.


After taking into account co and confounders, Dr. Agarwal R, the lead scientist also found, "A maximum mean difference of 31.20% was observed between vehicle-treated and extract treated eyes in water loading model while a maximum mean IOP lowering of 31.29% was observed in a steroid-induced model of glaucoma".


Although aqueous extract isolated from Foeniculum vulgare demonstrated a strong efficacy against the oculohypotensive activity, scientists participated in the study were still worry about the existence of possible toxicity.

The study reconfirmed the use of Fennel seeds to benefit vision in traditional herbal medicine and the Romans viewed the fennel plant as the herb of eyesight.

However, due to the limitation of information findings, patients with hyper intraocular pressure should consult with related field specialists before applying fennel extract.

Moreover, intake of fennel extract should be taken extreme care, as overdoses may induce to prevent liver toxicity and damage to eyesight



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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.


Sources
(1) Oculohypotensive effects of foeniculum vulgare in experimental models of glaucoma by Agarwal R1, Gupta SK, Agrawal SS, Srivastava S, Saxena R.(PubMed)