Diabetes is a chronic condition caused by insufficient insulin entering the bloodstream to regulate the glucose.
In other words, diabetes occurs when cells in the pancreas dying off or receptor sites clogged up by fat and cholesterol. In some cases, diabetes is also caused by allergic reactions of cells in the immune system.
The pancreas is an oblong flattened gland in the digestive and endocrine system located in the abdomen. By secreting pancreatic juice to the small intestine, the pancreas helps to break down carbohydrates, proteins, and lipids.
Traditional Chinese medicine views the pancreas as a vital organ that is responsible for the absorption of foods' qi and nutrients before passing them to other organs to nourish our bodies.
According to statistics, diabetes is one of the most common diseases in the US. Approximately 10% or 29.1 million people in the United States have diabetes, accompanied by 8.1 million that are undiagnosed and unaware of their condition.
About 1.4 million new cases of diabetes are diagnosed in the United States every year. More than one in every 10 adults who are 20 years or older has diabetes.
Hyperglycemia, a medical condition of abnormally high blood glucose, is a major concern, in people with both type 1 and type 2 diabetes.
Most cases of hyperglycemia occurred in patients who do not manage their diabetes properly.
Hyperglycemia, a hallmark of diabetes has been found to induce diabetics complications, including neuropathy, nephropathy, and retinopathy). ...
Oleanolic acid is a phytochemical in the subclass of triterpenoid, belongings to the group of Terpenes found abundantly in honey mesquite, garlic, java apple, clove, etc.
On finding a potential plant that processes anti-chronic disease activity researchers examined the hematological effects of oleanolic acid (OA) in streptozotocin- (STZ-) induced diabetic rats.
The study included animals that were separated into five groups; the nondiabetic group (ND), the diabetic control group (DC), and the treatment groups of insulin (170 μg/kg, s.c), metformin (500 mg/kg, p.o), and OA (80 mg/kg, p.o). OA was administered orally twice a day.
According to the results of the analysis,
* Untreated diabetic rats exhibited hyperglycemia, elevated glycated hemoglobin (HbA1c), oxidative stress, and a reduced erythropoietin (EPO) concentration when compared to ND rats.
* The administration of OA attenuated hyperglycemia, HbA1c, and EPO concentrations compared to DC rats.
* Furthermore, OA also decreased the blood glucose concentration, HbA1c, and improved EPO concentrations associated with a notable increase in red blood cell (RBC) count and other RBC indices.
* Moreover, OA increased the antioxidant status of the RBCs with a concomitant decrease in oxidative stress.
Collectively, researchers said, "These findings suggest that OA improves diabetes-induced hematological changes caused by hyperglycemia and attenuates the progression of cardiovascular complications in DM individuals".
Taken altogether, oleanolic acid may be considered a remedy for the prevention and treatment of diabetes, pending to the confirmation of the larger sample size and multicenter human study.
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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) The Haematological Effects of Oleanolic Acid in Streptozotocin-Induced Diabetic Rats: Effects on Selected Markers by Baloyi CM1, Khathi A1, Sibiya NH2, Ngubane PS. (PubMed)
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