Cancer is a class of diseases in which a group of cells growing and multiplying disorderly and uncontrollably in our body.
Most cases of cancer begin in the cells on the surface of the inner lining tissues of the organ or gland. At the early stage, most cancers are asymptomatic.
The digestive system included the gastrointestinal tract, the liver, pancreas, and gallbladder play a critical role to maintain the body normal function by providing nutrients and fluids to the body and remove waste through the secretary system.
The gastrointestinal tract formed part of the digestive system is a series of hollow organs that form a long continuous passage from our mouth to our anus, including our mouth, esophagus, stomach, small intestine, large intestine, and anus.
Gastrointestinal cancer is a medical and chronic condition caused by the alternation of cell DNA in the gastrointestinal tract including the esophagus, stomach, biliary system, pancreas, small intestine, large intestine, rectum, and anus.
The most common gastrointestinal cancer is gastric cancer, which is the fourth most commonly occurring cancer in men and the seventh most commonly occurring cancer in women.
According to worldwide statistics, over 1 million new cases were diagnosed in 2018 with the South Korean leading the map, second to Mongolia.
In other words, if you are Asian, you are at an increased risk of gastric cancer.
At the advanced stage, the cancer cell of the affected tissues can travel a distance away to infect the other tissues and organs, leading to secondary metastasis.
Epidemiologically, primary gastrointestinal cancer is more likely to spread to the stomach, esophageal cancer, breast cancer, renal cell carcinoma, and ovarian cancer.
The exact causes of gastrointestinal cancer are not identified. However, genetic preposition, unhealthy lifestyle, and medical conditions are some of the prevalent risks of the disease.
Some researchers suggested that a poor diet may have a strong implication on the incidence of gastrointestinal cancer.
Omega-3 fatty acids are phytochemicals in the class of lipids, found abundantly in deepsea fisk, dark-green leafy vegetables, grains, legumes, nuts, etc.
The three main components of Omega-3 fatty acids are alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).
On finding a potential phytochemical for the treatment of digestive diseases, researchers examined the effects of omega-3 polyunsaturated fatty acids (n-3 PUFAs), particularly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) on gastrointestinal (GI) cancer.
* n-3 PUFAs may exert their anticancer actions by influencing multiple targets implicated in various stages of cancer development.
* n-3 PUFAs especially imposed excellent actions of antiinflammation and antioxidation, as well as their restorative actions against gastrointestinal cancer developing by restoring or modifying the inflammation-associated lipid distortion and alteration of lipid rafts.
* However, the study of the effects of n-3 PUFAs against GI cancer is still limited.
Taken altogether, Omega-3 fatty acids found abundantly in fish oil and plant oil may be considered a functional food for the prevention and treatment of GI cancer, pending to the confirmation of the larger sample size and multicenter human study.
Intake of Omega-3 fatty acids in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Omega-3 polyunsaturated Fatty acids as potential chemopreventive agent for gastrointestinal cancer by Park JM1, Kwon SH1, Han YM2, Hahm KB3, Kim EH. (PubMed)
(2) Potential applications of fish oils rich in omega-3 polyunsaturated fatty acids in the management of gastrointestinal cancer by Eltweri AM1, Thomas AL2, Metcalfe M3, Calder PC4, Dennison AR3, Bowrey DJ. (PubMed)
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