Herbal Comfrey(Symphytum officinale L.) Promotes Bone Density in Vivo

Bone is a hard whitish tissue making up the skeleton in humans which provides a framework for the attachment of muscles and other tissues.

Bone density is the amount of bone mineral in bone tissue. Loss of bone density is found to induce osteoporosis.

Bone density is measured by the young adult bone density mean within 1 standard deviation (+1 or −1). The negative T-score is an indication of loss or lower bone density and the T-score of −2.5 or lower is an indication of osteoporosis.

Risk factors of losing bone density include gender, (women are more likely to develop osteoporosis compared to men) the increase in age, race, (African Americans have both lower rates of bone density loss and osteoporosis), family history.

People with low bone mass accompanied by progressive bone density loss over time are associated with an increased risk of developing osteoporosis.

Low bone mass is a risk factor of osteoporosis, The condition may also increase the incidence of bone fracture if it is accompanied by other risk factors.

Osteoporosis is a condition of thinning of bone and bone tissues as a result of the loss of bone density over a long period of time.

It is a widespread degenerative disease of skeletal joints and often associated with senescence in the vertebrates due to excessive or abnormal mechanical loading of weight-bearing joints, arising from heavy long-term use or specific injuries.

If you experience symptoms of lower back pain, loss of height over time, a stooped posture, easy bone fracture, neck and back pain,..., you may have osteoporosis.

Truly, bone diseases in children have been found to affect normal growth and development that can lead to weakness and/or deformity.

Comfrey is a perennial plant in the genus of Symphytum, belonging to the family Boraginaceae, native to Europe. It has been used in herbal and traditional medicine to ease excessive bleeding or on open wounds, relieve pain and swollen, treat circulation issues, reduce cholesterol, etc.

On finding a potential compound for the treatment of osteoporosis, researchers investigated the effect of Symphytum officinale (Comfrey) in homeopathic potency (6cH), on the removal torque and radiographic bone density around titanium implants, inserted in rats tibiae.

Selected rats induced loss of bone density in the study were randomized into a group of control and group treated by S. officinale 6cH.

According to the evaluation at 7, 14, 28, and 56 days post-implantation, removal torque of the implants rats treated the S. Officinale 6cH showed to enhance bone formation around the micro-implants at 14 days.

At 56 days, the radiographic bone density was higher in the treated group, compared to control.

Based on the findings, researchers said, " S. Officinale 6cH enhances, principally at the early stages of osseointegration, bone formation around titanium implants in rats' tibiae, based on the radiographic and mechanical analysis.".

Taken altogether, Comfrey combined with other herbal medicine may be considered a remedy for the promotion of bone density, pending to the confirmation of the larger sample size and multicenter human study.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Homeopathic Symphytum officinale increases removal torque and radiographic bone density around titanium implants in rats by Spin-Neto R1, Belluci MM, Sakakura CE, Scaf G, Pepato MT, Marcantonio E Jr. (PubMed)