Tocopherols Protect the Heart Against the Risk of Cardiovascular Diseases CVD

Cardiovascular disease (CVD) is a group of conditions associated with the heart and blood vessels.

In other words, anything that serves to damage the inner lining of blood vessels and impedes the transportation of oxygen and nutrition to the heart can be defined as a risk of heart disease.

The causes of cardiovascular diseases are associated with the accumulation of plaques in the arteries, impeding the blood flow which carries the nutrients and oxygen to the heart, which causes damage to the heart tissue and reduced function of the arteries.

In other words, high blood pressure, high blood cholesterol, smoking, diabetes, weight, depression, and family history associated with the early onset of plaques accumulated and impeding function of the arteries are the prevalent risk factors of cardiovascular diseases.

According to the statistics cardiovascular disease is the leading cause of death in women in the US with 90% of women having one risk factor.

Believe it or not, women are 4 times more likely to die from heart disease than breast cancer and 2/3 of women are not aware of heart disease is such a risk for them, according to the Jean Hailes for Women Health in the article cardiovascular health.

According to statistics, heart disease is the second leading cause of death, claiming more than 48,000 lives every year.in Canada.

Tocopherols are phytochemicals of which many have vitamin E activity, belonging to the group of Lipids, found abundantly in butter, egg yolk, milk fat, some vegetable, and seed or nut oils, etc.

On finding a potential phytochemical for the treatment of chronic diseases, researchers examined the effect of tocotrienol on oxidative stress and inflammation in the manifestation of aging-related cardiovascular disease.

According to the analysis, vitamin E supplement demonstrated significant activity in reducing the expression of oxidative stress induced by chronic inflammation.

More precisely, the efficacy of vitamin E that decreases the oxidative stress-induced cardiovascular disease was attributed to the presence of chemical compounds tocotrienols and tocopherols

More precisely, tocopherols, a class of Vitamin E compounds showed a lesser antioxidative and anti-inflammatory activity compared to those of tocotrienols (the other class of Vitamin E compounds), in ameliorating aging-related cardiovascular diseases and its associated morbidities.

Based on the results, researchers said, "the potential of tocotrienols in improving inflammation, dyslipidemia and mitochondrial dysfunction in aging-related cardiovascular diseases...".

Taken altogether, tocopherols may be considered a supplement for reducing the risk of cardiovascular diseases, pending to the confirmation of the larger sample size and multicenter human study.

Intake of tocopherols in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Tocotrienol is a cardioprotective agent against aging-associated cardiovascular disease and its associated morbidities by Ramanathan N1,2, Tan E3, Loh LJ3, Soh BS3,4,5, Yap WN. (PubMed)