The stomach located between the esophagus and the small intestine is a muscular, hollow and important organ of the digestive tract.
The stomach plays a critical role to assist the digestive system in digesting foods by secreting acid and enzymes.
Cancer is a class of chronic diseases associated with irregular cell growth in the tissues of the affected organ.
Stomach cancer is a condition of abnormal growth of the mucus-producing cells of the inside lining of the stomach. Adenocarcinoma is the most common type of stomach cancer.
According to the statistics, most cases of gastric/stomach cancer are found in older people. The average age of people when they are diagnosed is 68. The risk of developing gastric/stomach cancer in a man lifetime is about 1 in 95.
Most patients with stomach cancer in the early stage are asymptomatic.
However, at the later stage, patients may experience symptoms of pain and/or discomfort in the stomach area, mild ache in the upper part of the body, difficulty swallowing, feeling full or bloated after a small mealy, and vomiting blood or having blood in the stool accompanied by general symptoms shared by other types of cancer, including unintentional weight, loss, loss of energy, tiredness, nausea, and vomiting and loss of appetite.
The causes of gastric cancer are debatable, but some researchers suggested that people with chronic
gastrointestinal reflux disease (GERD), a condition caused by the frequent backflow of stomach acid into the esophagus, is the most likely to develop the disease.
Other diseases associated with the early onset of gastric cancer are obesity and smoking.
According to the Universidad de Salamanca, bacteria and viruses, including Helicobacter pylori are strongly associated with chronic gastritis, clinical syndromes, precancerous lesions, and pathogenesis of gastric cancer development.
Dandelion is a herbaceous perennial plant, genus Taraxacum, belongings to the family Asteraceae, native to temperate regions of the world. It has been used in traditional and herbal medicine to treat gout, eczema, acne, gall bladder, kidney, liver and urinary disorders, hypoglycemia, dyspepsia with constipation, edema, blood pressure, and heart weakness, chronic joint, skin diseases, etc.
On finding a natural ingredient for the prevention and treatment of chronic diseases, scientists examined the effects of dandelion root extract (DRE) on gastric cancer.
According to the tested assays,
* Dandelion root extract (DRE) specifically and effectively suppresses proliferation and migration in human gastric cells without inducing toxicity in noncancerous cells.
* Long noncoding RNAs (lncRNAs) are known to promote tumorigenesis in many cancer types are downregulated by the injection of DRE, including the lncRNA colon cancer-associated transcript-1 (CCAT1) in the promotion of tumor progression.
* More importantly, the downregulation of CCAT1 was found to inhibit the proliferation and migration of gastric cells.
Based on the results, researchers suggest, "DRE exerted its function in GC cells partially through targeting CCAT1. This data will provide a basis on which further research in cancer treatment through DRE can be executed".
Taken altogether, Dandelion may be considered an antioxidant remedy for the treatment of gastric cancer, pending to the confirmation of the larger sample size and multicenter human study.
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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Dandelion root extract suppressed gastric cancer cells proliferation and migration through targeting lncRNA-CCAT1 by Zhu H1, Zhao H2, Zhang L1, Xu J1, Zhu C1, Zhao H1, Lv G. (PubMed)
(2) Stomach cancer by Mayo Clinic
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