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Wednesday, June 17, 2020

Healthy Common Fig or Fig (Ficus carica) Protects the Risk of Pre-Diabetes in Health Individuals and Type 2 Diabetes

Glycemic response is a change in blood glucose after consuming carbohydrate-containing food compared to the Glycemic Index (GI) which is a ranking of carbohydrate-containing foods according to their effect on blood glucose levels.

Some researchers suggested that the glycemic response is the change of blood glucose after the intake of a food or meal.

Most healthy individuals have normal blood glucose and insulin levels that rise within the range after eating, then return to the fasting levels over a short period of time.

According to the epidemiological studies, controlling the glycaemic response with the healthy range, can reduce the risk of type 2 diabetes.

Including additional fiber into a meal or food may have a strong implication in reducing the levels of glucose shortly after intake.

Insulin resistance, a hallmark in patients with type II diabetes is the condition in which the cells in tissues that start to resist or ignore the signal of the hormone insulin.

In other words, the insulin produced by the body no longer can convert glucose to energy even with the presence of the hormone insulin, leading to high levels of glucose in the bloodstream.

According to the statistics provided by the CDC, approximately, 1 in 3 people in the United States have prediabetes, including half of those aged 60 and older.

People with insulin resistance have been found to increase the risk for prediabetes, type 2 diabetes, and other serious health problems, such as cardiovascular disease and cancer.

Although researchers do not know the exact cause of insulin resistance, they do not certain risk factors such as genetic preposition, aging, and ethnicity are associated with the onset of the condition.

However, an unhealthy lifestyle that causes excess body weight, too much belly fat, smoking, and lack of exercise are the most prevalent factors in the Western world.


Fig is a species of F. Carica, belonging to the family Moraceae. It is a deciduous shrub, native to Southeast Asia. The tree can grow to a height of 33 ft and the fruit can be as large as 2.0 inches.

On finding natural compounds for reducing the risk of diabetes researchers examined the effects of two fig fruit extracts (FFEs) on postprandial glycemic and insulinemic responses.

The standard glucose drink and randomized, double-blind crossover study included 10 healthy adults consumed 4 test beverages containing FFE with postprandial glucose and insulin assessed at regular intervals over 2 h to determine GI and II responses.

According to the experiemnetal reslultd, test beverages containing 200 mg FFE-50× and 1200 mg FFE-10× significantly reduced GI values by -25% tP = 0.001) and -24% (P = 0.002), respectively.
Furthermore, two lower doses of FFE also reduced GI values compared with the reference drink (by approximately -14%), with no statistical significance.
Moreover, addition of FFE to the glucose solution also was found to induce a significantly reduced values at all dosages and display a clear dose-response reduction: FFE-50× at 100 mg and 200 mg (-14% (P < 0.05) and -24% (P = 0.01), respectively) and FFE-10× at 600 mg and 1200 mg (-16% (P < 0.05) and -24% (P = 0.01), respectively).


Based on the evidence, researchers said, " FFE supplementation is a promising nutritional intervention for the management of acute postprandial glucose and insulin homeostasis, and it is a possible adjunctive treatment for glycemic management of chronic metabolic disorders such as prediabetes and type 2 diabetes mellitus"

Taken altogether, common fig or fig (Ficus carica) may be considered a remedy for the prevention and treatment of prediabetes, pending to the confirmation of the larger sample size and multicenter human study.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Abscisic Acid Standardized Fig (Ficus carica) Extracts Ameliorate Postprandial Glycemic and Insulinemic Responses in Healthy Adults by Atkinson FS1, Villar A2, Mulà A2, Zangara A3,4, Risco E2, Smidt CR5, Hontecillas R6, Leber A6, Bassaganya-Riera J. (PubMed)

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