Healthy Food Cabbage Processes Anti-Proliferative Activities in Vitro

Cancers are the class of diseases caused by alteration of DNA that initiates healthy cells to grow disorderly and uncontrollably.

At the later stage, the cancerous cells may travel a distance away from the original site to infect healthy cells of other tissue and organs.

Cancers are the second leading cause of death worldwide besides heart diseases.

According to a statistic from the Canada Government, approximately 1 in 2 Canadians will be diagnosed with cancer during their lifetime, and 1 in 4 will die from the disease.

The most common types of cancer in Canada include lung, colorectal, breast and prostate cancers. And these 4 cancers are account for half of all cancers diagnosed in Canada.

Believe or not, 1/4 of cancers death are due to lung cancer.

Depending on types of cancer, people with cancers may experience general and specific symptoms.

The American Cancer Society wrote, "Cancer may also cause symptoms like fever, extreme tiredness (fatigue), or weight loss. Because cancer cells use up much of the body’s energy supply, or they may release substances that change the way the body makes energy from food. Cancer can also cause the immune system to react in ways that produce these signs and symptoms" and " Sometimes, cancer cells release substances into the bloodstream that cause symptoms that are not usually linked to cancer. For example, some cancers of the pancreas can release substances that cause blood clots in veins of the legs".

DNA alternation is the major cause of diseases.

Proliferation is a condition of rapid cell multiplication used by the cancer cells to grow indefinitely.

Normal cycle multiplication has a limited cell cycle division before replacing by the new cell.

In cancer cells, the cell cycle division is unlimited


In cancer, antiproliferative activities is a process to inhibit the growth of cancer cells

Cabbage is a species of Brassica oleracea belongings to the family Brassicaceae (or Cruciferae), native to the Mediterranean region along the seacoast. The veggie has a short stem with a crowded mass of leaves, usually green but in some varieties, it may be red or purplish.

On findings a natural wholefood for the treatment of cancer, researchers examined the heterodimeric 13.8 kDa napin-like polypeptide that has previously been isolated from Chinese cabbage (Brassica parachinensis) seed on leukemia (L1210) cells.

According to the tested analysis, the selected compound stimulated nitrite production by mouse peritoneal macrophages against the tested cells.

In other words, polypeptide blocks the cell cycle division activity by inhibiting cancer cell proliferation.

Furthermore, the tested compound also stimulated the immune macrophages to reduce the viability of leukemia (L1210) cells through its immunomodulatory activity.


More precisely, the heterodimeric 13.8 kDa napin-like polypeptide processes a strong anti-cancer cell proliferative property.

Taken altogether, cabbage contains high levels of phytochemicals which process anticancer cell proliferative activities, pending to the confirmation of the larger sample size and multicenter human study.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) The trypsin-inhibitory, immunostimulatory and antiproliferative activities of a napin-like polypeptide from Chinese cabbage seeds by Ng TB1, Ngai PH. (PubMed)