Coffee, A Potent and Functional Food in Reduced Risk of Endometrial Cancer

Intake of caffeinated coffee may have reduced risk and treatment of Endometrial cancer, an Asian joint study supposed.

Coffee, becoming a popular and social beverage all over the world, particularly in the West, is a drink made from roast bean from the Coffea plant, native to tropical Africa and Madagascar.

Endometrial cancer is a medical condition characterized by cell growth disorderly and uncontrollably in the endometriosis. In the later stage, cancer can spread to distant parts of tissues or organs.

In the review of published data of a total 1,534,039 participants from 13 published articles added in this meta-analysis, researchers found that reduced risk of endometrial cancers incidence is associated to coffee intake to patients never treated with any forms hormone therapies and either overweight or obese.

The relative odd ratio in these group of people were 0.66 and 0.77, respectively, correlated to decaffeinate and caffeine coffee intake.

In fact, the risk of endometrial cancer decreased by 5% for every additional cup of coffee consumed.

In compared to decaffeinate coffee, caffeinated coffee showed a stronger in the attenuated risk of 7% instead of 4% in decaffeinated intake,

The study also addressed that caffeine found in coffee may have potential in enhanced coffee effects in ameliorated endometrial cancer expression. Risk of cancer is reduced by 4% for every 100mg caffeine intake per day.


In a 26 years follow-up study of 67,470 female participants aged 34 to 59 in 1980 of the Nurses' Health Study (NHS), returned questionnaires by the participants indicated that
1. Women drinking less than 4 cups of coffee per day were not associated with endometrial cancer risk.
2. Women drinking more than 4 cups coffee per day displayed a 25% decreased risk of endometrial cancer compared to women who drank fewer than 1 cup per day.

Dr. Je Y, the lead author said, "For decaffeinated coffee consumption, a suggestive inverse association was found among women who consumed 2 or more cups per day versus <1 cup/mo."


Interestingly, the menopause women, the primary analyses included 45,696 women and 427 incident endometrial cancer cases, diagnosed over a total of 342,927 person-years of follow-up, suggested that
1. No association of endometrial cancer risk in coffee consumption in compared to non-daily drinkers (none or <1 cup/day),
2. Women who drank ≥4 cups/day have a relative odd ration of were 0.86. 0.63, for total coffee with 0.89 for caffeinated coffee, and 0.51 (95% CI 0.25, 1.03) for decaf coffee.
3. In obese women, compared to control group (none or <1 cup/day), women who drank ≥2 cups/day had a relative odd ratio of 0.72 for total coffee, 0.66 for caffeinated coffee. and 0.67 decaffeinated coffee drinkers.


Taking together, the intake of coffee is associated with a reduced risk of endometrial cancer in healthy and menopause women regardless of weight mass.


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Author Biography
Kyle J. Norton, Master of Nutrition
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Coffee consumption and risk of endometrial cancer: a dose-response meta-analysis of prospective cohort studies by Zhou Q1, Luo ML2, Li H3, Li M4, Zhou JG5.(PubMed)
(2) A prospective cohort study of coffee consumption and risk of endometrial cancer over a 26-year follow-up by Je Y1, Hankinson SE, Tworoger SS, De Vivo I, Giovannucci E.(PubMed)