Inflammation is a natural defense of the immune system that protects the body against the invasion of the foreign pathogens.
Acute inflammation occurs quickly or within the hours and lasts a few days or weeks.
In the acute phase of inflammation, damage tissues are healed itself after all pathogens are killed off.
However, if the immune system can not completely destroy all invaders in the acute phase of infection within 3 to 8weeks, it will compromise, leading to chronic low-grade inflammation, a major cause of cardiovascular disease, arthritis, and diabetes.
In most cases, depending on the types of injury, overproduction of pro-inflammatory cytokines in the acute phase of infection can cause damage to the nearby healthy tissues, leading to the formation of scars.
Anti-inflammatory is a process that inhibits the inflammatory symptoms without affecting the pro-inflammatory function of killing microorganisms.
Conventionally, the most common use of anti-inflammatory medicine for the treatment of symptoms induced by pro-inflammatory cytokines are Nonsteroidal anti-inflammatory drugs (NSAIDs) focusing on pain relief, inclduing aspirin, ibuprofen (Advil, Motrin, Midol) and naproxen (Aleve, Naprosyn).
If you are planning to take them in a long-term, please make sure that you know all the side effects.
Tomato is red, edible fruit, genus Solanum, belonging to family Solanaceae, native to South America. Because of its health benefits, the tomato is grown worldwide for the commercial purpose
and often in the greenhouse.
On finding healthy food for the treatment of diseases associated with inflammation, researchers examined the tomato effects on the inflammation that causes intestinal dysbiosis associated with the onset of inflammatory bowel diseases (IBD).
The study included Winnie mice, a model of spontaneous ulcerative colitis received chows enriched with 1% Bronze tomato.
According to the tested assays, at week 2, the Bronze-enriched chow administered showed no macroscopic effect on the IBD symptoms. However, at the molecular level, the Bronze-enriched chow demonstrated significant activity in the activation of anti-inflammatory genes.
According to the intracellular staining of T cells, proteins associated with the production of pro-inflammatory cytokines ( IL17A, IFNγ) were significantly inhibited by the injection of Bronez tomato.
Based on the analysis of the microbial composition, researchers also found that two weeks of Bronze enriched diet was sufficient to alter positively the microbial composition of the tested subjects.
In other words, polyphenols found in the Bronze tomato has created unfavorable conditions for bad bacterial species in the gastrointestinal tract to stimulate the progression of IBD.
Dr. Liso M, the lead scientist wrote, after taking other factors into account, "dietary regimes enriched in polyphenols may efficiently support IBD remission affecting the intestinal dysbiosis:.
Taken altogether, tomato may be considered a dietary supplements for the prevention and treatment of IBD, pending to large sample size and multicenter human study.
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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) A Bronze-Tomato Enriched Diet Affects the Intestinal Microbiome under Homeostatic and Inflammatory Conditions by Liso M1, De Santis S2, Scarano A3, Verna G4, Dicarlo M5, Galleggiante V6, Campiglia P7, Mastronardi M8, Lippolis A9, Vacca M10, Sobolewski A11, Serino G12, Butelli E13, De Angelis M14, Martin C15, Santino A16, Chieppa M. (PubMed)
(2) Impact of Dietary Tomato Juice on Changes in Pulmonary Oxidative Stress, Inflammation and Structure Induced by Neonatal Hyperoxia in Mice (Mus musculus) by Bouch S1, Harding R1, O'Reilly M1, Wood LG2, Sozo F. (PubMed)
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