All About Vitamins: Vitamin A deficiency induces Xerophthalmia

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Vitamin A, a bi-polar molecule formed by bonds between carbon and hydrogen, is a fat soluble vitamin which can not be stored in the liver but it can be converted from beta-carotene, a powerful antioxidant. The vitamin is best known fir its strong effects in improving vision and enhancing bone growth.

Xerophthalmia is a abnormal dryness of the conjunctiva and cornea of the eye as a result of vitamin A deficiency induced of inflammation. The disease can lead to blindness in patient with vitamin A deficiency.(1).

Even though the disease is rare in Western World, but in children of a developed country, vitamin A deficiency is common. In a fifty-two of the 146 children had VAD, with average age was 8.4 years (range 11 days to 18 years old) joint study lead by The University of Sydney, suggested that Vitamin A deficiency and xerophthalmia do exist in children of developed country(2).

Dr. Sommer A said, "Treatment(included xerophthalmia) is practical and inexpensive, based upon the oral administration of 200,000 IU vitamin A on two successive days, at a cost of 10 cents"(3).

In fact, according to both UNICEF and the World Health Organization (WHO), Control of vitamin A deficiency induceing xerophthalmia is now a major health challenge and goal in develop world and considered as a late manifestation of severe deficiency rather than of early, mild deficiency(4)

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Sources
(1) Epidemiology of vitamin A deficiency and xerophthalmia in at-risk populations by Sherwin JC1, Reacher MH, Dean WH, Ngondi J.(PubMed)
(2) Vitamin A deficiency and xerophthalmia in children of a developed country by Chiu M1, Dillon A2, Watson S1,3.(PubMed)
(3) Xerophthalmia, keratomalacia and nutritional blindness by Sommer A1(PubMed)
(4) Xerophthalmia and vitamin A status by Sommer A1(PubMed)