Coffee Intake Daily and Regularly in Increased Risk Of Laryngeal Cancer?

Epidemiological studies do not agree that coffee and coffee caffeine may have potential in reduced risk and treatment of laryngeal cancer.

Laryngeal cancer is a medical condition of irregular cell growth in the tissues of the larynx. The cancer cells may spread to other tissues and organs in the late stage.

Coffee, a popular and social beverage all over the world, particularly in the West, is a drink made from roast bean from the Coffea plant, native to tropical Africa and Madagascar.

In the review literature of a total of 2,803 cases and 503,234 controls in 10 independent studies identified by searching electronic database (Medline and EMBASE) and reviewing the reference lists of relevant articles until Oct. 2013, researchers found that incidence of laryngeal cancer was associated to coffee consumption, in compared to nondrinkers. Intake of coffee showed a significant relative risk of RR = 1.47 in compared to baseline.

Interestingly, researchers found, no statistically significant association of cancer incident difference in comparison between moderate and low coffee drinking.

According to the study, there was evidence of statistically significant association of the dose of coffee consumption and the risk of laryngeal cancer.

Dr. Chen J, the lead researcher said, " A dose-response relationship between coffee intake and laryngeal carcinoma was detected" and "this meta-analysis of observational studies demonstrate that coffee consumption would increase the laryngeal cancer risk".

According to the result published, the study also identified that among the 6 studies that reported the association between coffee consumption and laryngeal carcinoma, only one study was a prospective population-based cohort study, while the rest 5 studies were retrospective hospital-based case-control studies using observation of returned survey from participants.

Contrastively, also in the searching of database PubMed, Web of Knowledge and Wan Fang Med Online, identified 8 studies including 2167 laryngeal cancer cases, researchers insisted that there was an insignificant association between coffee and coffee caffeine intake and risk of laryngeal cancer, regardless to volumes intake.

Taking together, coffee and coffee caffeine intake may have a negative effect on increased risk and laryngeal cancer but researchers suggested that genetic and environmental factors such as alcohol intake, human papillomaviruses infection, and silica exposure should be also taken into account. which were excluded in some studies before expressing.


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Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Tea and coffee consumption and risk of laryngeal cancer: a systematic review meta-analysis by Chen J1, Long S1.(PMC)
(2) Association between tea and coffee consumption and risk of laryngeal cancer: a meta-analysis by Ouyang Z1, Wang Z2, Jin J1.(PubMed)