Carotenoids Protect the Eyes Against Age Related Eye Disease

Age-related eye disease is a class of medical conditions associated with vision impairment due to aging.

Most common types of age-related eye disease are
* Age-related macular degeneration (AMD) is a medical condition that causes irreversible blurring of the central vision in people over age 60.

The most common symptoms of AMM are slightly blurred central vision. Most cases of the early stage of AMD were diagnosed during routine eye health examinations.

Over time, age-related macular degeneration may affect the vision including the reading as the blurred area increased in size.

The risk factor associated AMD is shadowy areas in your central vision or unusually fuzzy or distorted vision, particularly in seeing wavy or blurred, with some dark areas at the center.

* Cataract
A cataract occurred in one or both eyes is a condition characterized by the clouding of the lens in the eye that affects vision. Most cases of cataract are found in older adults.

Believe it or not, by age 80, more than half of all Americans either have a cataract or have had cataract surgery.

The risk factor associated cataracts are aging, a lifetime of exposure to ultraviolet radiation contained in sunlight, cigarette smoking, a poor diet, and alcohol consumption are some of the prevalent factors associated with cataract developing.


* Diabetic eye disease
Diabetic eye disease is a severe complication of diabetes, a leading cause of blindness as a result of damage to the tiny blood vessels inside the retina.

The risk factor associated with diabetic eye disease is an uncontrol diet and poor management of blood glucose.

* Glaucoma
Glaucoma is a medical condition of eye disease as a result of the damage of the nerve of the eye’s optic over time. If left untreated, it can lead to permanent vision impairment and blindness.

The risk factor associated AMD are abnormal intraocular pressure (IOP), history of coronary artery bypass or vascular surgery, moderate-to-high myopia, medical conditions such as diabetes, heart diseases, high blood pressure, and hypothyroidism and long-term use of certain medication such as a corticosteroid.

Conventionally, there is no cure of the diseases, treatment of age-related eye disease is focusing on the improvement of quality of life, reduce symptoms and slow down the progression.

Carotenoids are a class of mainly yellow, orange, or red fat-soluble pigments, including lycopene and carotene, found abundantly in ripe tomato, pumpkins, carrots, corn, and daffodils.

With an aim to find a natural ingredient for the prevention and treatment of eye diseases, researchers the antioxidant and anti-inflammatory activities of carotenoids and polyphenols.

The study included the search of medical literature on PubMed and Web of Science databases for original studies that investigate the benefits of different carotenoids and polyphenols in age-related ophthalmic diseases.


According to the differentiation of the selected studies, carotenoids (such as lutein, zeaxanthin, and neoxanthin) exerted significant preventive and therapeutic benefits against the aforementioned age-related eye diseases.

The efficacy of carotenoids in the protection of the age-related vision was attributed to the phytochemicals in
* Mitigating the production of reactive oxygen species, through its antioxidant activity.

* Inhibiting the tumor necrosis factor-α and vascular endothelial growth factor pathways involved in the stimulation of the formation of blood vessels in age-related ocular diseases.

*Protecting the cells in the eye against the overexpression of pro-inflammatory cytokines

* Suppressing the gene associated with cell apoptosis

Based on the finding, researchers wrote, "This review discusses the role and mechanisms of ...carotenoids and their possible synergistic effects on the prevention and treatment of age-related eye diseases that are induced or augmented by oxidative stress and inflammation".

Taken altogether, carotenoids may be considered a remedy for the prevention and treatment of age-related eye diseases, pending to the confirmation of the larger sample size and multicenter human study.

Intake of carotenoids in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Health Benefits of Polyphenols and Carotenoids in Age-Related Eye Diseases by Bungau S1, Abdel-Daim MM2,3, Tit DM1, Ghanem E4, Sato S3, Maruyama-Inoue M3, Yamane S3, Kadonosono K. (PubMed)
(2) The role of the carotenoids, lutein and zeaxanthin, in protecting against age-related macular degeneration: A review based on controversial evidence by Maneli Mozaffarieh,1 Stefan Sacu,1 and Andreas Wedrich. (PMC)