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Wednesday, October 18, 2017

All About Vitamins: Vitamin B5 Improved Intestinal Bacterial Expression

By Kyle J. Norton.

Vitamin B5 is also known as pantothenic acid, played an important role in the forming of co-enzyme A and critical in the metabolism and synthesis of carbohydrates, proteins and fat. Vitamin B5 has a chemical structure formula of C9H17NO5.

Vitamin B5 deficiecy may have a negative effect in balancing the gut bacterial expression, a recent study suggested.

And, long term PA deficiency may induced weight loss or reduced growth, hair loss and exudation around the eyes, then diarrhea and hindleg paralysis and splenomegaly, and finally death.

According to Dr. Tautt J. in the experiments carried out to test the length of time necessary to induce vitamin deficiency by removing vitamins from the diet or by giving the rabbits antibiotics of different activity spectrum when the animals kept on a diet without vitamins, said, "(observation by microbiological assay) the time after which changes in vitamin levels developed as well as the intensity of changes differ, depending on the experimental model used, but the sequence of vitamin disappearance from the organism is always the same. The first to disappear were vitamins B1, followed by vitamin B6 and pantothenic acid".

Truly, in the evaluated intestinal pantothenic acid (PA) uptake in mice fed diets with high, normal and deficient PA levels researchers found that
1, Treatment of antibitics have a positive effect to reduced intestinal pantothenic acid (PA)
2. Dietary PA levels had no effect on intestinal PA uptake at 5 microM

There fore, the study postulated, " intestinal transporters may be regulated only for vitamins absorbed predominantly by carrier-mediated transport and subject to natural deficiency states."

Taking altogether, there is no doubt that vitamin B5 deficiency caused by environment ethanol and intake of antibiotics may have a significant effect in over exhibition of bacterial expression in  inducing intestinal disorder,

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(1) Changes in the levels of certain vitamins from B group under conditions of vitamin deficiency by Tautt J.(PubMed)
(2) Do dietary levels of pantothenic acid regulate its intestinal uptake in mice?by Stein ED1, Diamond JM.(PubMed)

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

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