All About Vitamins: Vitamin B6 for Treatment of Nausea and Vomiting in Early Stage of Pregnancy

By Kyle J. Norton.


Intake of vitamin B6 in the early stage of pregnancy may have a profound effect in reduced symptoms of nausea and vomiting, a renowned study suggested.

Vitamin B6, also known as pyridoxine, is a water soluble vitamin found abundantly in green peas, yams, broccoli, asparagus and turnip greens,Peanuts, sunflower seeds, cashews and hazelnuts, meat, fish etc., with functions of amino acid, carbohydrate metabolism, brain health, and liver detoxification, etc.

In a comparison of the effects of quince fruit and vitamin B6 intake on symptoms of mild-to-moderate nausea and vomiting (NVP) of 76 pregnant women with a gestational age of 6-14 weeks presented (40 in the quince and 36 in the B6 group), researchers found that
1. The score of the PUQE was decreased from 8.4 at baseline to 7.3 and 7.7 on the 14th day (p < .001) in the vitamin B6 group, respectively
2. Symptoms of mild-to-moderate nausea and vomiting (NVP) also decreased in both groups, according to assay

Although vitamin B6 intake group showed a significantly reduced symptoms of mild-to-moderate nausea and vomiting in lesser effective in compared to quince (Cydonia oblonga) fruit group.
Dr. Jafari-Dehkordi E, the led researchers, due to the nature of stage of pregnancy said," Pregnancy-induced nausea and vomiting (NVP) is one of the most common problems during gestation. Treatment is mainly symptomatic, ranging from dietary changes and oral pharmacological treatment to hospitalization in severe forms. In early pregnancy, the use of chemical drugs is avoided, so there is an increasing tendency to use alternative therapies".

Additionally, in a triple blind clinical trial on pregnant women suffering mild to moderate NVP between 6 and 16 weeks of pregnancy randomized assign to ginger, 500 mg twice daily, vitamin B6 40 mg twice daily and placebo twice daily for 4 days, according to the returned questionnaire, researchers filed the following results
1. All 3 groups pisplayed a significant improvement of nausea
2. All 3 group expressed a similar reduction of vomiting but lesser effective in placebo
3. Both Ginger and vitamin B6 groups reduced the severity of all items of Rhodes questionnaire significantly but less effective in frequency of nausea, intensity of vomiting and frequency of retching in compared to placebo.
4. Ginger and vitamin B6 groups did not show significant difference in total score in Rhodes

Dr. Sharifzadeh F, after taking into account of other factors, such as age, gestational age, parity, and severity of each symptom, said, "Ginger is more effective than placebo for the treatment of mild to moderate NVP and comparable to vitamin B6".

In support of the above differentiation, the study a 126 pregnant women, with a gestational age of < or = 16 weeks who had nausea and vomiting, required anti-emetics, had no medical complication, and not hospitalized, randomly allocated to receive either 650 mg of ginger or 25 mg of vitamin B6 conducted by the Bangkok Metropolitan Administration Medical College and Vajira Hospital, researchers illustrated that
1. Ginger and vitamin B6 significantly reduced scores
2. Vitamin B6 even thought improved symptoms of nausea and vomiting,but lesser effective in compared to ginger group.
3. Side effect of both group are well tolerated.

Taking altogether, there is no doubt that vitamin B6 may be used as therateutic treatment in reduced symptoms of nausea and vomiting in early stage of pregnancy

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Sources


Biography
Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Comparison of quince with vitamin B6 for treatment of nausea and vomiting in pregnancy: a randomised clinical trial by Jafari-Dehkordi E1, Hashem-Dabaghian F1, Aliasl F2, Aliasl J1, Taghavi-Shirazi M1, Sadeghpour O1, Sohrabvand F3, Minaei B4, Ghods R1.(PubMed)
(2) A comparison between the effects of ginger, pyridoxine (vitamin B6) and placebo for the treatment of the first trimester nausea and vomiting of pregnancy (NVP) by Sharifzadeh F1, Kashanian M1, Koohpayehzadeh J2, Rezaian F1, Sheikhansari N3, Eshraghi N1.(PubMed)
(3) Comparison of the effectiveness of ginger and vitamin B6 for treatment of nausea and vomiting in early pregnancy: a randomized double-blind controlled trial by Chittumma P1, Kaewkiattikun K, Wiriyasiriwach B.(PubMed)