All About Vitamins: Vitamin B5 (Pantothenic acid) in Reduced Risk and Treatment of Acne

By Kyle J. Norton.

Vitamin B5 is also known as pantothenic acid, played an important role in the forming of co-enzyme A and critical in the metabolism and synthesis of carbohydrates, proteins and fat. Vitamin B5 has a chemical structure formula of C9H17NO5.

Pantothenic acid may have a profound effect in reduced risk and treatment in acne, according to the renowned institute study.

In a randomized, double-blind, placebo-controlled study of adults previously diagnosed with mild to moderate acne vulgaris randomized to application of pantothenic acid-based dietary supplement, or a placebo for 12 weeks (endpoint), group treated pantothenic acid-based dietary supplement with showed a significant mean reduction in total lesion count in compared to placebo at week 12.

According to the Global Assessment and Dermatology Life Quality Index (DLQI) scores, pantothenic acid-based dietary supplement group scored a higher expression in a reduced effect in facial skin inflammation as well.

In fact and more precisely, the application showed a significantly reduced area-specific with acne and inflammatory blemishes.

Dr. Yang M, the lead researchers said, "Administration of a pantothenic acid-based dietary supplement in healthy adults with facial acne lesions is safe, well tolerated and reduced total facial lesion count versus placebo after 12 weeks of administration".

Other researchers also expressed  a concern of acne besides caused by hormone factors, it may also be induced in person with vitamin B5 deficiency.

Dr. Leung LH, said, "a radically different theory for its pathogenesis and relate its basic pathology to a deficiency in pantothenic acid, a vitamin hitherto not known to cause any deficiency syndrome in humans. Hence, the effect of hormonal factors in this disease entity becomes secondary to that of the availability of pantothenic acid".

Taking altogether, there is no doubt that vitamin B5 have a therapeutic effect in reduced risk and treatment of acne vulgaris, particular in patients with pantothenic acid deficiency.

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Biography
Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) A randomized, double-blind, placebo-controlled study of a novel pantothenic Acid-based dietary supplement in subjects with mild to moderate facial acne by Yang M1, Moclair B, Hatcher V, Kaminetsky J, Mekas M, Chapas A, Capodice J.(PubMed)
(2) Pantothenic acid deficiency as the pathogenesis of acne vulgaris by Leung LH1.(PubMed)