All About Vitamins: Vitamin B5(Pantothenic acid) Deficiency in Risk Of Osteoarthritis

By Kyle J. Norton.

Vitamin B5 is also known as pantothenic acid, played an important role in the forming of co-enzyme A and critical in the metabolism and synthesis of carbohydrates, proteins and fat. Vitamin B5 has a chemical structure formula of C9H17NO5.

Pantothenic acid deficiency may be associated to risk of osteoarthritis, a study by renowned institute suggested.

In the study of 77 osteoarthritis patients assessed biweekly for 12 weeks as part of a multidisciplinary approach to the management of osteoarthritis, nutrient information and food frequency questionnaire returned by patients, showed a significantly correlated between obesity pain from osteoarthritis and vitamins deficiency, particularly vitamin B5.

According to the study, obese osteoarthritis patients may benefit from weight loss if meal were chosen with care to include nutrients in which they are deficient.

Dr. White-O'Connor B, the lead author said, " In addition to providing nutritional recommendations to avoid dietary deficiencies, a registered dietitian can assist in the multidisciplinary treatment of osteoarthritis by providing weight-control counseling and follow-up".

In deed, further differentiation showed that  dietary intake of these group of patients were below 80% of pantothenic acid, the recommended dietary allowance daily. 

Other, in the study of vitamin therapy in the absence of obvious deficiency opinionated that deficiency of vitamin may lead to a specific deficiency syndrome, which may be primary (due to inadequate diet) or secondary (due to malabsorption or to increased metabolic need), and it is rational to use high-dose vitamin supplementation in situations where these clinical conditions exist and vitamin B5 deficiency is associated to increased risk and progression of osteoarthritis.

Dr. Ovesen L. said, "Most of the vitamins have been reported to cause adverse effects when ingested in excessive doses" and "therefore worthwhile to consider the risk-benefit ratio before embarking upon the use of high-dose vitamin supplementation for disorders were proof of efficacy is lacking".

Taking altogether, vitamin B5 deficiency may be one of major factor in increased incidence and progression of osteoarthritis, therefore intake of supplement may be necessary but please consult with your doctor before applying in large doses.

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Sources


Biography
Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Nutrient intake and obesity in a multidisciplinary assessment of osteoarthritis by White-O'Connor B, Sobal J.(PubMed)