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Wednesday, October 25, 2017

All About Vitamins: Vitamin B6 in Iron Deficiency Anemia Pregnancy

By Kyle J. Norton.

Administration of vitamin B6 in pregnancy of women with iron deficiency may improve iron status, a National Center for Child Health and Development, Tokyo study suggested.

Vitamin B6, also known as pyridoxine, is a water soluble vitamin found abundantly in green peas, yams, broccoli, asparagus and turnip greens,Peanuts, sunflower seeds, cashews and hazelnuts, meat, fish etc., with functions of amino acid, carbohydrate metabolism, brain health, and liver detoxification, etc.

According to the study, generally, pregnant women with iron anemia are exclusively treated with iron supplementation, but in several women who were nonresponsive to iron supplementation may require injection of high dose of vitamin B6.

The study also found that ecen healthy pregnant women may also experience lower levels of blood levels of iron, ferritin and vitamin B6 by the third trimester in compared the nonpregnant reference range.

Dr. Hisano M, the led author said, " it is important to take into account the deficiency of vitamin B6 besides iron in the evaluation of anemiaduring pregnancy".

Other, in the study of most common form of inherited sideroblastic anemia, X-linked sideroblastic anemia (XLSA) caused by a novel mutation on the ALAS2 gene, in pregnant women suggested that in prevent side effect of high-dose vitamin B6 intake in pregnancy, low dose of pyridoxine may be necessary in the beginning than increased gradually in post-partum

Further observation, researchers also indicated  that pyridoxine supplementation injected over 3 months in iron deficient pregnancy women also displayed
1. An decreased levels of serum ferritin and
2  Normalized transferrin saturation, hemoglobin content and serum hepcidin level, and
3. Improved morphologic red cell abnormalities remarkably.

However, in the study 250 women with chronic post hemorrhagic iron deficiency anemia diagnosed in 175 patients, and 75 iron deficiency anemia, group treated with addition of iron, vitamins B12 and B6, copper sulfate and the combination of iron with the vitamin B group and copper sulfate did not show any improvement in the rate of hemoglobin, erythrocytes and serum iron in compared to non treatment groups.

Taking altogether, Vitamin B6 may play an important role in reduced complications of iron deficiency anemia pregnancy, but a large sample size and cohost study are necessary to clarify these inconclusion.

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Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

(1) Vitamin B6 deficiency and anemia in pregnancy by Hisano M1, Suzuki R, Sago H, Murashima A, Yamaguchi K.(PubMed)
(2) Microcytic anemia in a pregnant woman: beyond iron deficiency by Rollón N1, Fernández-Jiménez MC, Moreno-Carralero MI, Murga-Fernández MJ, Morán-Jiménez MJ.(PubMed)
(3) [Are any drug admixtures except iron preparations required in the treatment of iron deficiencyanemia?].[Article in Russian] by Mandel'baum AIa(PubMed)

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