Broccoli Protects the Neurons in Post Myocardial Infarction

Acute brain infarction is the severe and medical emergency characterized by the obstruction of the blood supply to the brain, causing the local death of the neurons in the brain. Prompt treatment can minimize brain damage and potential complications.

The occurrence and extent of brain infarction are associated with three basic factors, including the site of arterial occlusion, the rapidity of arterial occlusion, and the presence or absence of collateral circulation.

In other words, brain infarction can be classified into myocardial infarction due to plaque rupture and myocardial oxygen supply-demand imbalance secondary to other acute illnesses.

The exact causes of a blood clot that induce acute brain infarction are unknown. However, the trouble with speaking and understanding, confusion, sudden numbness, weakness or paralysis in your face, arm or leg, headache and the trouble with walking are some of the most common symptoms found in patients with post-myocardial infarction.

Depending on the severity of the acute infarction, in serious cases, patients may also experience symptoms, paralysis of the face, arm or leg, trouble with seeing in one or both eyes.

Although, there are many factors associated with the risk of acute infarction. some researchers suggested an unhealthy diet may have a strong and negative implication on the onset of the condition.

Dr. Guo J, the lead scientist at the Peking Union Medical College & Chinese Academy of Medical Sciences wrote, "Some dietary patterns are risk factors for acute myocardial infarction (AMI)".
And, "Several dietary frequencies (serves per week) including vegetables, fruits and tofu were closely associated with a decrease of AMI risk. Carbohydrate pattern showed a weak relationship with AMI. We observed a U-shaped association between frequencies of fat and protein pattern and AMI risk. Excessive fat intake increased the AMI risk.".

With an aim to find a natural food for the prevention and treatment of heart disease, researchers examined the effect of sulforaphane found in broccoli against myocardium from ischaemic reperfusion injury by comparing the fresh broccoli and cooked broccoli cardioprotection.

Broccoli is a mustard/cabbage plant, belong to the family Brassicaceae. The veggie has large flower heads, usually green in color and the mass of flower heads surrounded by leaves and evolved from a wild cabbage plant on the continent of Europe.

The study compared the two groups of rats that were fed with fresh (steamed) broccoli or cooked broccoli for 30 d, while a third group was given a vehicle only for the same period of time.

Based on the differentiation of isolated working hearts that were subjected to 30 min ischemia followed by 2 h of reperfusion. 30 min ischemia followed by 2 h of reperfusion, both cooked and steamed broccolis displayed significantly improved post-ischemic ventricular function and reduced myocardial infarction and cardiomyocyte apoptosis compared to control.

Additionally, both cooked and steamed broccolis demonstrated significantly enhanced the induction of the survival signaling proteins and inhibition of death signaling proteins associated with heart tissue damage.

Furthermore, both cooked and steamed broccoli also protected the heart cells against the overexpression of free radicals by enhancing the levels of antioxidants.

However, steamed broccoli was found to be more cardioprotective abilities compared to those of cooked broccoli.

Moreover, levels of Trx2 and Trx reductase associated with redox activity were only enhanced in the steamed broccoli group.

Based on the findings, researchers said, " The results of the present study documented superior cardioprotective properties of the steamed broccoli overcooked broccoli because of the ability of fresh broccoli to perform redox signaling of Trx".

Taken altogether, broccoli processed abundantly SFN may be considered supplements as a cardioprotective remedy, pending to the confirmation of the larger sample size and multicenter human study.
Intake of SFN in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Comparison of the protective effects of steamed and cooked broccolis on ischaemia-reperfusion-induced cardiac injury by Mukherjee S1, Lekli I, Ray D, Gangopadhyay H, Raychaudhuri U, Das DK. (PubMed)
(2) Influence of dietary patterns on the risk of acute myocardial infarction in China population: the INTERHEART China study by Guo J1, Li W, Wang Y, Chen T, Teo K, Liu LS, Yusuf S; INTERHEART China study investigators. (PubMed)