Gamma-linolenic Acid Reduces the Risk of Non-Ischemic Heart Failure

The heart is a four-chambered, hollow muscle and a double-acting pump located in the chest between the lungs is a muscular organ in the human body.

The heart formed an important part of the circulatory system that pumps blood through the blood vessels to nourish the body and assist in the removal of metabolic wastes.

Non-ischemic Heart Failure is a type of heart failure that is not associated with ischemic heart failure.

According to the statistic provided by the American Heart Foundation, on average, an American dies of CVD every 38 seconds. Cardiovascular disease (CVD) accounted for 840,678 deaths in the US in 2016 and the condition also claims more lives each year than all forms of cancer and chronic lower respiratory disease combined

In 2016, cardiovascular diseases cause the death of 2,303 deaths each day, in the US.
Cardiovascular disease is defined as medical conditions affecting the cardiovascular system, including heart, blood vessels(arteries and veins).


Ischemic heart disease is defined as a condition of reduced blood supply of the heart muscle, as a result of coronary artery disease caused by plaque building up in the arteries.

Heart failure is a medical condition characterized by insufficiently maintaining blood flow to meet the body's needs, inducing symptoms of
* Shortness of breath and excessive tiredness are caused by the congestion in your lungs in the process of inhaling oxygen and exhaling carbon dioxide.
And* Leg swelling is a condition caused by fluid to back up in your lungs and in other parts of your body such as your ankles.

Believe it or not, approximately 600, 000 Canadian are living with heart failure or 16% of the entire population.

Gamma-linolenic acid is a phytochemical in the group of Omega-3, 6,9 fatty acids, belongings to the class of Lipids, found abundantly in evening primrose, borage, blackcurrant, etc.

On finding a potential plant that processes anti-heart diseases activity researchers examined the effect of polyunsaturated fatty acids (PUFAs) on heart failure (HF).

The study included 50 patients with stable non-ischemic HF who underwent CPETs at our hospital.

According to the results of the analysis of the relationships between PUFAs and echocardiographic findings as well as CPET and other test parameters in patients' data.
* Correlations were significantly negative between dihomo-γ-linolenic acid (DGLA) + arachidonic acid (AA) and heart failure.

* Minute ventilation versus carbon dioxide production (VE/VCO2) slope, were positive between N-terminal pro-B-type natriuretic peptide (NT-proBNP) and VE/VCO2 slope in heart failure.

* More profoundly, eicosapentaenoic acid (EPA) + docosahexaenoic acid (DHA) were not significantly correlated with the CPET parameters.

Based on the evidence, researchers said, " Low levels of circulating DGLA+AA and AA among PUFAs were associated with decreased exercise responses in patients with stable non-ischemic HF".

Taken altogether, potato may be considered a functional food for the prevention and treatment of non-ischemic heart failure, pending to the confirmation of the larger sample size and multicenter human study.


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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) The Relationship between Circulating Polyunsaturated Fatty Acid Levels and Exercise Responses of Patients with Non-ischemic Heart Failure by Izumida S1, Kawano H1, Muroya T2, Motokawa T1, Akashi R1, Yonekura T1, Morimoto Y3, Yano Y3, Ikeda S1, Maemura K. (PubMed)